What is the cheapest airline to fly from Panama City, Florida to Santa Ana round-trip?

Cheapflights users have booked flights from Panama City, Florida to Santa Ana round-trip from $654.

What is the cheapest day to fly from Panama City, Florida to Santa Ana?

Travelers seeking maximum savings on their Panama City, Florida to Santa Ana flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santa Ana ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santa Ana, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What is the cheapest day to fly round-trip from Panama City, Florida to Santa Ana?

Thursday flights are generally found to be more expensive for flights from Panama City, Florida to Santa Ana. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Santa Ana.

How far in advance should I book a flight from Panama City, Florida to Santa Ana?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 32 days in advance, which can save you up to 149% on flights from Panama City, Florida to Santa Ana compared to booking the week you need them. Waiting 32 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $659. For sooner than that we have options available in the next 3 days from $758.

What is the cheapest month to fly from Panama City, Florida to Santa Ana?

October can be a great time to fly to Santa Ana from Panama City, Florida with a flight ticket averaging about $436. Cheapflights users have found deals in the month of October for as cheap as $214. The most expensive prices can be found in the month of August.

What is the cheapest time of day to fly from ECP to SNA?

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Santa Ana at noon. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight in the morning.

Can I find deals for flights from Panama City to Santa Ana that include hotel bookings?

Yes. In addition to deals on Panama City to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santa Ana.

Can I find deals for business class flights from Panama City to Santa Ana?

Yes. Cheapflights offers flight deals from Panama City to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$259+ Flights from Panama City, FL to Santa Ana

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Cheap flight deals from Panama City to Santa Ana

Round-trip from	$654 (United Airlines)
One-way from	$259 (Delta)
Popular in	February
Cheapest in	January
Average price	$418

From Panama City NW Florida Beaches to Santa Ana J. Wayne/Orange Cnty

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One-way flight from Panama City NW Florida Beaches to Santa Ana J. Wayne/Orange Cnty

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Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($25 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Panama City to Santa Ana

Cheapest flights from Panama City to Santa Ana
Explore the most affordable flight options available from Panama City to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Thu 9/115:06 pmECP - SNA

1 stop6h 27mUnited Airlines

Sun 9/148:15 amSNA - ECP

1 stop6h 05mUnited Airlines

Deal found 7/29

$654

Best flights from Panama City to Santa Ana
Discover carefully curated flight deals from Panama City to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2025.

Thu 9/115:06 pmECP - SNA

1 stop6h 27mUnited Airlines

Sun 9/148:15 amSNA - ECP

1 stop6h 05mUnited Airlines

Deal found 7/29

$654

One-way flights from Panama City to Santa Ana
Search for one-way flight options from Panama City to Santa Ana. Find affordable one-way fares based on user searches. Data last updated July 30, 2025.

Sun 9/286:00 amECP - SNA

1 stop7h 03mDelta

Deal found 7/30

$259

Fri 8/156:30 amECP - SNA

1 stop6h 29mUnited Airlines

Deal found 7/30

$304

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Thu 9/11

5:06 pm-9:33 pm

1 stop6h 27m

Santa Ana J. Wayne/Orange Cnty

Sun 9/14

8:15 am-4:20 pm

1 stop6h 05m

$654

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Sun 9/28

6:00 am-11:03 am

1 stop7h 03m

$259

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 8/15

6:30 am-10:59 am

1 stop6h 29m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Panama City to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santa Ana

What is the cheapest month to book a flight from Panama City, Florida to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Santa Ana (average of $298). Flying from Panama City, Florida to Santa Ana in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Read through reviews of airlines operating flights from Panama City to Santa Ana, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,980 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,896 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What is the cheapest airline to fly from Panama City, Florida to Santa Ana round-trip?
Cheapflights users have booked flights from Panama City, Florida to Santa Ana round-trip from $654.
Can I find deals for flights from Panama City to Santa Ana that include hotel bookings?
Yes. In addition to deals on Panama City to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santa Ana.
Can I find deals for business class flights from Panama City to Santa Ana?
Yes. Cheapflights offers flight deals from Panama City to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to Santa Ana?
Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Santa Ana (average of $298). Flying from Panama City, Florida to Santa Ana in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Other flights to Santa Ana

Top airline flying from Panama City to Santa Ana

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$346	Average$632	FlexibilityNo cancel fee	On-time71%

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$259+ Cheap flights from Panama City, FL to Santa Ana (ECP - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Santa Ana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to Santa Ana

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Panama City to Santa Ana

Cheapest flights from Panama City to Santa AnaExplore the most affordable flight options available from Panama City to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Explore the most affordable flight options available from Panama City to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Santa Ana that are best for you.

Best time to book a flight from Panama City to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santa Ana

What is the cheapest month to book a flight from Panama City, Florida to Santa Ana?

Reviews of airlines servicing Santa Ana

Read through reviews of airlines operating flights from Panama City to Santa Ana, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What is the cheapest airline to fly from Panama City, Florida to Santa Ana round-trip?

Can I find deals for flights from Panama City to Santa Ana that include hotel bookings?

How can I find direct flights from Panama City to Santa Ana?

Can I find deals for business class flights from Panama City to Santa Ana?

What is the cheapest month to book a flight from Panama City, Florida to Santa Ana?

Traveling to a place near Santa Ana?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Panama City to Santa Ana

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Panama City to Santa Ana
Explore the most affordable flight options available from Panama City to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.