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$219+ Cheap flights from Panama City, FL to Santa Ana, CA (ECP - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SNA
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Find flight deals from Panama City to Santa Ana

Cheapest flights from Panama City to Santa Ana
Explore the most affordable flight options available from Panama City to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Southwest deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:30 pmECP - SNA
2 stops8h 10mSouthwest
Tue 1/66:40 pmSNA - ECP
2 stops13h 05mSouthwest
Deal found 11/16$487
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:18 pmECP - SNA
1 stop8h 52mAmerican Airlines
Sun 12/1412:43 pmSNA - ECP
1 stop6h 33mAmerican Airlines
Deal found 11/17$497
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 amECP - SNA
1 stop15h 27mAmerican Airlines
Tue 1/612:52 pmSNA - ECP
1 stop6h 27mAmerican Airlines
Deal found 11/16$611
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/244:26 pmECP - SNA
1 stop7h 53mDelta
Fri 11/286:45 amSNA - ECP
1 stop6h 36mDelta
Deal found 11/16$624
This Southwest deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:30 pmECP - SNA
2 stops8h 10mSouthwest
Sat 12/2711:55 amSNA - ECP
2 stops8h 40mSouthwest
Deal found 11/16$627
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:02 amECP - SNA
2 stops11h 22mDelta
Sat 11/2912:45 pmSNA - ECP
1 stop8h 22mDelta
Deal found 11/16$629
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/248:21 amECP - SNA
2 stops12h 03mAmerican Airlines
Sun 11/309:30 amSNA - ECP
1 stop8h 30mAmerican Airlines
Deal found 11/16$715

Cheap flight deals from Panama City to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$487
(Southwest)

One-way from

$219
(United Airlines)

Popular in

February

Cheapest in

July

Average price

$717
Provider with most accurate pricing for Panama City NW Florida Beaches-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Panama City NW Florida Beaches to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Panama City NW Florida Beaches to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($133 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Panama City to Santa Ana that are best for you.

Fly from

Panama City

Fly to

Santa Ana

Route

Depart

Return

Price

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 1/9

1:32 pm-8:04 pm

1 stop8h 32m

Santa Ana J. Wayne/Orange Cnty

Mon 1/12

7:30 am-10:51 pm

2 stops13h 21m

$442

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 1/9

10:30 am-7:35 pm

2 stops11h 05m

Santa Ana J. Wayne/Orange Cnty

Mon 1/12

8:30 am-6:10 pm

2 stops7h 40m

$447

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Tue 12/23

9:50 am-4:15 pm

2 stops8h 25m

Santa Ana J. Wayne/Orange Cnty

Tue 1/6

6:40 pm-9:45 am

2 stops13h 05m

$487

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Thu 12/11

6:30 am-1:57 pm

1 stop9h 27m

Santa Ana J. Wayne/Orange Cnty

Sun 12/14

12:43 pm-9:16 pm

1 stop6h 33m

$497

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 1/16

6:30 am-11:21 am

1 stop6h 51m

$219

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 1/16

3:27 pm-10:56 pm

1 stop9h 29m

$219

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Thu 12/18

5:00 pm-10:30 pm

1 stop7h 30m

$319

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 1/16

5:14 pm-9:27 pm

3 stops54h 13m

$673

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Compare providers for flights from Panama City to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Santa Ana in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santa Ana

What is the cheapest month to book a flight from Panama City, Florida to Santa Ana, California?

Currently, November is the cheapest month in which you can book a flight from Panama City, Florida to Santa Ana, California (average of $103). Flying from Panama City, Florida to Santa Ana, California in August is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated November 17, 2025.
Read through reviews of airlines operating flights from Panama City to Santa Ana, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,048 reviews

Food

6.4

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,048 reviews
American Airlines
7.2
Good
11,048 reviews

Food

6.4

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Santa Ana, California?

    Departing from Panama City, Florida to Santa Ana, California will take you 8h 32m. The distance from Panama City, Florida to Santa Ana, California is about 1884 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City, Florida to Santa Ana, California round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Santa Ana, California round-trip from $339. American Airlines is 36% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Panama City, Florida to Santa Ana, California one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $219. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Panama City, Florida to Santa Ana, California for a low price.

  • Can I find deals for flights from Panama City to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Panama City to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santa Ana.

  • Can I find deals for business class flights from Panama City to Santa Ana?

    Yes. Cheapflights offers flight deals from Panama City to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Santa Ana, California?

    Currently, November is the cheapest month in which you can book a flight from Panama City, Florida to Santa Ana, California (average of $103). Flying from Panama City, Florida to Santa Ana, California in August is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
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Top airline flying from Panama City to Santa Ana

Discover the top airline that operate flights from Panama City to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$339Average$467FlexibilityNo cancel feeOn-time71%

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