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$307+ Cheap flights from Panama City, FL to Santa Ana (ECP - SNA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SNA
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Panama City to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$307
(American Airlines)

Popular in

February

Cheapest in

January

Average price

$798
From Panama City NW Florida Beaches to Santa Ana J. Wayne/Orange Cnty
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Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Panama City to Santa Ana

Cheapest flights from Panama City to Santa Ana
Explore the most affordable flight options available from Panama City to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:47 pmECP - SNA
1 stop7h 28mAmerican Airlines
Wed 12/176:45 amSNA - ECP
1 stop5h 24mAmerican Airlines
Deal found 8/12$307
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:20 amECP - SNA
1 stop7h 40mSouthwest
Thu 10/307:15 amSNA - ECP
2 stops9h 30mSouthwest
Deal found 8/12$372
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:30 amECP - SNA
1 stop7h 35mSouthwest
Sun 11/99:10 pmSNA - ECP
2 stops9h 55mSouthwest
Deal found 8/12$404
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:00 amECP - SNA
1 stop8h 42mDelta
Sun 8/317:45 amSNA - ECP
1 stop8h 13mDelta
Deal found 8/12$432
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2712:06 pmECP - SNA
2 stops9h 51mAmerican Airlines
Sun 8/316:55 pmSNA - ECP
2 stops12h 43mAmerican Airlines
Deal found 8/12$442

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Panama City to Santa Ana that are best for you.

Fly from

Panama City

Fly to

Santa Ana

Route

Depart

Return

Price

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 12/12

2:47 pm-8:15 pm

1 stop7h 28m

Santa Ana J. Wayne/Orange Cnty

Wed 12/17

6:45 am-2:09 pm

1 stop5h 24m

$307

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Thu 10/23

7:20 am-1:00 pm

1 stop7h 40m

Santa Ana J. Wayne/Orange Cnty

Thu 10/30

7:15 am-6:45 pm

2 stops9h 30m

$372

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 11/7

7:30 am-1:05 pm

1 stop7h 35m

Santa Ana J. Wayne/Orange Cnty

Sun 11/9

9:10 pm-9:05 am

2 stops9h 55m

$404

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Wed 8/27

6:00 am-12:42 pm

1 stop8h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 8/31

7:45 am-5:58 pm

1 stop8h 13m

$432

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Wed 8/27

12:06 pm-7:57 pm

2 stops9h 51m

Santa Ana J. Wayne/Orange Cnty

Sun 8/31

6:55 pm-9:38 am

2 stops12h 43m

$442

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Thu 12/11

2:47 pm-8:15 pm

1 stop7h 28m

$669

Panama CitySanta Ana

ECP - SNA

ECPSNA

Panama City NW Florida Beaches

Fri 12/12

2:47 pm-8:15 pm

1 stop7h 28m

$679

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Panama City to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santa Ana

What is the cheapest month to book a flight from Panama City, Florida to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Santa Ana (average of $298). Flying from Panama City, Florida to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated August 14, 2025.
Read through reviews of airlines operating flights from Panama City to Santa Ana, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Crew

8.0

Entertainment

6.9

Boarding

7.5

Overall

7.2

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Crew

8.0

Entertainment

6.9

Boarding

7.5

Overall

7.2

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City, Florida to Santa Ana round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Santa Ana round-trip from $307. Another airline that can offer you cheap pricing is Southwest. Users have found that American Airlines is 45% cheaper than the other options available to this destination.

  • Can I find deals for flights from Panama City to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Panama City to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santa Ana.

  • Can I find deals for business class flights from Panama City to Santa Ana?

    Yes. Cheapflights offers flight deals from Panama City to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Santa Ana (average of $298). Flying from Panama City, Florida to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

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Top airline flying from Panama City to Santa Ana

Discover the top airline that operate flights from Panama City to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$346Average$632FlexibilityNo cancel feeOn-time71%

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