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$149+ Cheap flights from Myrtle Beach to Santa Ana, CA (MYR - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SNA
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Myrtle Beach to Santa Ana

Cheapest flights from Myrtle Beach to Santa Ana
Explore the most affordable flight options available from Myrtle Beach to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/179:05 amMYR - SNA
2 stops28h 11mSpirit Airlines
Tue 1/611:11 amSNA - MYR
2 stops27h 57mSpirit Airlines
Deal found 10/28$323
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:40 pmMYR - SNA
2 stops10h 24mDelta
Tue 1/611:59 amSNA - MYR
1 stop8h 44mDelta
Deal found 10/28$364
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/181:54 pmMYR - SNA
1 stop9h 03mAmerican Airlines
Wed 11/198:55 amSNA - MYR
1 stop7h 00mAmerican Airlines
Deal found 10/28$377
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/182:41 pmMYR - SNA
2 stops10h 47mDelta
Wed 11/196:45 amSNA - MYR
1 stop8h 10mDelta
Deal found 10/28$382
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:54 amMYR - SNA
2 stops15h 33mSpirit Airlines
Tue 1/611:11 amSNA - MYR
3 stops27h 57mSpirit Airlines
Deal found 10/28$398
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/173:29 pmMYR - SNA
1 stop7h 23mAmerican Airlines
Tue 1/67:00 amSNA - MYR
1 stop7h 04mAmerican Airlines
Deal found 10/29$399
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1211:13 amMYR - SNA
3 stops28h 23mSpirit Airlines
Sun 11/161:31 pmSNA - MYR
3 stops29h 55mSpirit Airlines
Deal found 10/28$418
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:39 pmMYR - SNA
1 stop9h 37mDelta
Tue 1/611:59 amSNA - MYR
1 stop8h 44mDelta
Deal found 10/28$429
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/232:46 pmMYR - SNA
3 stops29h 05mSpirit Airlines
Wed 11/261:27 pmSNA - MYR
3 stops27h 36mSpirit Airlines
Deal found 10/29$471

Cheap flight deals from Myrtle Beach to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$323
(Mytrip)

One-way from

$149
(CheapOair)

Popular in

December

Cheapest in

August

Average price

$454
Provider with most accurate pricing for Myrtle Beach Intl-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Myrtle Beach Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Myrtle Beach Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($54 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Santa Ana that are best for you.

Fly from

Myrtle Beach

Fly to

Santa Ana

Route

Depart

Return

Price

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Thu 1/22

9:59 am-8:59 pm

2 stops14h 00m

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

5:46 pm-10:41 am

2 stops13h 55m

$286

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 12/17

9:05 am-10:16 am

2 stops28h 11m

Santa Ana J. Wayne/Orange Cnty

Tue 1/6

11:11 am-6:08 pm

2 stops27h 57m

$323

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 12/17

2:40 pm-10:04 pm

2 stops10h 24m

Santa Ana J. Wayne/Orange Cnty

Tue 1/6

11:59 am-11:43 pm

1 stop8h 44m

$364

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 11/18

1:54 pm-7:57 pm

1 stop9h 03m

Santa Ana J. Wayne/Orange Cnty

Wed 11/19

8:55 am-6:55 pm

1 stop7h 00m

$377

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 11/18

2:41 pm-10:28 pm

2 stops10h 47m

Santa Ana J. Wayne/Orange Cnty

Wed 11/19

6:45 am-5:55 pm

1 stop8h 10m

$382

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 12/23

9:54 am-10:27 pm

2 stops15h 33m

Santa Ana J. Wayne/Orange Cnty

Tue 1/6

11:11 am-6:08 pm

3 stops27h 57m

$398

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 12/17

3:29 pm-7:52 pm

1 stop7h 23m

Santa Ana J. Wayne/Orange Cnty

Tue 1/6

7:00 am-5:04 pm

1 stop7h 04m

$399

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 11/4

9:22 am-12:36 pm

3 stops30h 14m

$269

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 11/4

9:22 am-1:30 pm

2 stops31h 08m

$290

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 11/4

3:32 pm-7:57 pm

1 stop7h 25m

$440

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 16 results
1
2

Compare providers for flights from Myrtle Beach to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santa Ana in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Santa Ana

What is the cheapest month to book a flight from Myrtle Beach to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Santa Ana, California (average of $91). Flying from Myrtle Beach to Santa Ana, California in January is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SNA?

Find hourly flight availability from Myrtle Beach to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

One of the essential ways to save on airfare from Myrtle Beach to Santa Ana, California is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 32% on airfare.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with American Airlines from Myrtle Beach to Santa Ana by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,034 reviews

Overall

7.2

Boarding

7.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Food

6.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
11,034 reviews
American Airlines
7.2
Good
11,034 reviews

Overall

7.2

Boarding

7.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Food

6.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Santa Ana, California?

    Airlines like Spirit Airlines and Delta fly from Myrtle Beach to Santa Ana, California in about 10h 24m. The time it takes to get you to your destination can typically vary by up to 3h 36m. The distance from Myrtle Beach to Santa Ana, California is about 2224 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Myrtle Beach to Santa Ana, California round-trip?

    According to our current data, American Airlines ($319), offers the cheapest pricing from Myrtle Beach to Santa Ana, California. American Airlines is currently priced 38% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to Santa Ana, California one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $269. Users have also found prices from $440 and $491 on American Airlines and United Airlines, respectively.

  • Can I find deals for flights from Myrtle Beach to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santa Ana.

  • Can I find deals for business class flights from Myrtle Beach to Santa Ana?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Santa Ana, California?

    Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Santa Ana, California (average of $91). Flying from Myrtle Beach to Santa Ana, California in January is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

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Tustin

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Top airline flying from Myrtle Beach to Santa Ana

Discover the top airline that operate flights from Myrtle Beach to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$319Average$498FlexibilityNo cancel feeOn-time71%

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