How long is the flight from Myrtle Beach to Santa Ana, California?

Airlines like Spirit Airlines, Delta, and United Airlines fly from Myrtle Beach to Santa Ana, California in about 9h 52m. The time it takes to get you to your destination can typically vary by up to 7h 34m. The distance from Myrtle Beach to Santa Ana, California is about 2224 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What is the cheapest airline to fly from Myrtle Beach to Santa Ana, California round-trip?

According to our current data, American Airlines ($319), offers the cheapest pricing from Myrtle Beach to Santa Ana, California.

In terms of precipitation, rainfall in Santa Ana, California ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana, California when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santa Ana, California, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Most accurate provider : When it comes to deals on Myrtle Beach-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santa Ana, California flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Myrtle Beach-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Myrtle Beach to Santa Ana that include hotel bookings?

Yes. In addition to deals on Myrtle Beach to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Myrtle Beach to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santa Ana.

Can I find deals for business class flights from Myrtle Beach to Santa Ana?

Yes. Cheapflights offers flight deals from Myrtle Beach to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$353+ Flights from Myrtle Beach to Santa Ana, CA

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Cheap flight deals from Myrtle Beach to Santa Ana

Cheapest flights from Myrtle Beach to Santa Ana
Explore the most affordable flight options available from Myrtle Beach to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Wed 12/317:13 pmMYR - SNA

3 stops29h 58mSpirit Airlines

Mon 1/511:11 amSNA - MYR

2 stops27h 57mSpirit Airlines

Deal found 12/12

$512

Wed 12/312:34 pmMYR - SNA

1 stop9h 17mAmerican Airlines

Mon 1/56:45 amSNA - MYR

1 stop6h 48mAmerican Airlines

Deal found 12/12

$611

Sat 12/276:00 amMYR - SNA

1 stop7h 54mDelta

Wed 12/3112:05 pmSNA - MYR

1 stop7h 45mDelta

Deal found 12/12

$643

Wed 12/312:34 pmMYR - SNA

1 stop9h 17mAmerican Airlines

Sun 1/47:35 pmSNA - MYR

2 stops10h 45mAmerican Airlines

Deal found 12/12

$656

Wed 12/311:47 pmMYR - SNA

2 stops32h 09mUnited Airlines

Mon 1/57:05 pmSNA - MYR

2 stops14h 36mUnited Airlines

Deal found 12/12

$876

Best flights from Myrtle Beach to Santa Ana
Discover carefully curated flight deals from Myrtle Beach to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 14, 2025.

Wed 1/289:59 pmMYR - SNA

3 stops17h 26mSpirit Airlines

Fri 2/64:37 pmSNA - MYR

3 stops23h 43mSpirit Airlines

Deal found 12/12

$353

Sat 1/3112:35 pmMYR - SNA

2 stops10h 57mDelta

Mon 2/27:10 pmSNA - MYR

2 stops11h 36mDelta

Deal found 12/12

$395

Wed 1/281:25 pmMYR - SNA

1 stop9h 52mUnited Airlines

Fri 2/66:25 pmSNA - MYR

2 stops15h 04mUnited Airlines

Deal found 12/12

$417

Sat 1/3110:30 amMYR - SNA

2 stops9h 00mSouthwest

Mon 2/26:55 pmSNA - MYR

2 stops12h 20mSouthwest

Deal found 12/12

$426

Tue 2/108:15 pmMYR - SNA

3 stops27h 42mSpirit Airlines

Fri 2/131:20 pmSNA - MYR

2 stops15h 53mSpirit Airlines

Deal found 12/12

$389

Tue 2/101:25 pmMYR - SNA

1 stop9h 52mUnited Airlines

Fri 2/136:40 pmSNA - MYR

2 stops14h 05mUnited Airlines

Deal found 12/12

$417

Wed 12/317:13 pmMYR - SNA

3 stops29h 58mSpirit Airlines

Mon 1/511:11 amSNA - MYR

3 stops27h 57mSpirit Airlines

Deal found 12/12

$512

Sat 2/2112:26 pmMYR - SNA

1 stop10h 28mUnited Airlines

Wed 2/256:35 pmSNA - MYR

2 stops14h 44mUnited Airlines

Deal found 12/12

$562

Last-minute flights from Myrtle Beach to Santa Ana
Discover last-minute flight deals from Myrtle Beach to Santa Ana. Data last updated December 14, 2025 and is based on user searches.

Wed 12/317:13 pmMYR - SNA

3 stops29h 58mSpirit Airlines

Mon 1/511:11 amSNA - MYR

2 stops27h 57mSpirit Airlines

Deal found 12/12

$512

Wed 12/312:34 pmMYR - SNA

1 stop9h 17mAmerican Airlines

Mon 1/56:45 amSNA - MYR

1 stop6h 48mAmerican Airlines

Deal found 12/12

$611

Thu 1/152:19 pmMYR - SNA

1 stop8h 45mDelta

Mon 1/1911:55 amSNA - MYR

1 stop8h 46mDelta

Deal found 12/12

$579

Wed 1/289:59 pmMYR - SNA

3 stops17h 26mSpirit Airlines

Fri 2/64:37 pmSNA - MYR

3 stops23h 43mSpirit Airlines

Deal found 12/12

$353

Wed 1/281:53 pmMYR - SNA

1 stop9h 09mAmerican Airlines

Fri 2/67:00 amSNA - MYR

1 stop7h 04mAmerican Airlines

Deal found 12/12

$412

Wed 1/281:25 pmMYR - SNA

1 stop9h 52mUnited Airlines

Fri 2/66:25 pmSNA - MYR

2 stops15h 04mUnited Airlines

Deal found 12/12

$417

Sat 1/316:00 amMYR - SNA

1 stop8h 49mDelta

Mon 2/27:10 pmSNA - MYR

2 stops11h 36mDelta

Deal found 12/12

$390

Sat 1/311:53 pmMYR - SNA

1 stop9h 09mAmerican Airlines

Mon 2/27:50 amSNA - MYR

1 stop6h 14mAmerican Airlines

Deal found 12/12

$415

Sat 1/3110:30 amMYR - SNA

2 stops9h 00mSouthwest

Mon 2/26:55 pmSNA - MYR

2 stops12h 20mSouthwest

Deal found 12/12

$426

One-way flights from Myrtle Beach to Santa Ana
Search for one-way flight options from Myrtle Beach to Santa Ana. Find affordable one-way fares based on user searches. Data last updated December 14, 2025.

Mon 12/292:14 pmMYR - SNA

3 stops47h 02mMultiple Airlines

Deal found 12/12

$370

Mon 12/296:00 amMYR - SNA

1 stop7h 54mDelta

Deal found 12/12

$470

Find flight deals from Myrtle Beach to Santa Ana

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$353 (Mytrip)
Popular in	March
Cheapest in	September
Average price	$522

Provider with most accurate pricing for Myrtle Beach Intl-Santa Ana J. Wayne/Orange Cnty flight deals.

Search Deals

Provider most trusted by Cheapflights users for Myrtle Beach Intl-Santa Ana J. Wayne/Orange Cnty flights.

Search Deals

From Myrtle Beach Intl to Santa Ana J. Wayne/Orange Cnty

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($47 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 1/28

9:59 pm-12:25 pm

3 stops17h 26m

Santa Ana J. Wayne/Orange Cnty

Fri 2/6

4:37 pm-7:20 pm

3 stops23h 43m

$353

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 2/10

8:15 pm-8:57 pm

3 stops27h 42m

Santa Ana J. Wayne/Orange Cnty

Fri 2/13

1:20 pm-8:13 am

2 stops15h 53m

$389

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 1/31

12:35 pm-8:32 pm

2 stops10h 57m

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

7:10 pm-9:46 am

2 stops11h 36m

$395

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 1/28

1:25 pm-8:17 pm

1 stop9h 52m

Santa Ana J. Wayne/Orange Cnty

Fri 2/6

6:25 pm-12:29 pm

2 stops15h 04m

$417

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 2/10

1:25 pm-8:17 pm

1 stop9h 52m

Santa Ana J. Wayne/Orange Cnty

Fri 2/13

6:40 pm-11:45 am

2 stops14h 05m

$417

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 1/31

10:30 am-4:30 pm

2 stops9h 00m

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

6:55 pm-10:15 am

2 stops12h 20m

$426

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 12/31

7:13 pm-10:11 pm

3 stops29h 58m

Santa Ana J. Wayne/Orange Cnty

Mon 1/5

11:11 am-6:08 pm

3 stops27h 57m

$512

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 2/21

12:26 pm-7:54 pm

1 stop10h 28m

Santa Ana J. Wayne/Orange Cnty

Wed 2/25

6:35 pm-12:19 pm

2 stops14h 44m

$562

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Mon 12/29

10:40 am-10:16 am

2 stops50h 36m

$445

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Mon 12/29

6:00 am-10:54 am

1 stop7h 54m

$470

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/12

Compare providers for flights from Myrtle Beach to Santa Ana

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santa Ana in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Myrtle Beach-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santa Ana, California flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Myrtle Beach-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Myrtle Beach with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Santa Ana

What is the cheapest month to book a flight from Myrtle Beach to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Santa Ana, California (average of $91). Flying from Myrtle Beach to Santa Ana, California in December is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SNA?

One of the essential ways to save on airfare from Myrtle Beach to Santa Ana, California is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 32% on airfare.

Reviews of airlines servicing Santa Ana

Get a feel of what it's like to fly with American Airlines from Myrtle Beach to Santa Ana by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,054 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

American Airlines

7.2

Good

11,054 reviews

American Airlines

7.2

Good

11,054 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

How long is the flight from Myrtle Beach to Santa Ana, California?
Airlines like Spirit Airlines, Delta, and United Airlines fly from Myrtle Beach to Santa Ana, California in about 9h 52m. The time it takes to get you to your destination can typically vary by up to 7h 34m. The distance from Myrtle Beach to Santa Ana, California is about 2224 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What is the cheapest airline to fly from Myrtle Beach to Santa Ana, California round-trip?
According to our current data, American Airlines ($319), offers the cheapest pricing from Myrtle Beach to Santa Ana, California.
Can I find deals for flights from Myrtle Beach to Santa Ana that include hotel bookings?
Yes. In addition to deals on Myrtle Beach to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Myrtle Beach to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santa Ana.
Can I find deals for business class flights from Myrtle Beach to Santa Ana?
Yes. Cheapflights offers flight deals from Myrtle Beach to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Myrtle Beach to Santa Ana, California?
Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Santa Ana, California (average of $91). Flying from Myrtle Beach to Santa Ana, California in December is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Tustin

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Myrtle Beach to Santa Ana

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$319	Average$488	FlexibilityNo cancel fee	On-time71%

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$353+ Cheap flights from Myrtle Beach to Santa Ana, CA (MYR - SNA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Myrtle Beach to Santa Ana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Myrtle Beach to Santa Ana

Cheapest flights from Myrtle Beach to Santa AnaExplore the most affordable flight options available from Myrtle Beach to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Explore the most affordable flight options available from Myrtle Beach to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Find flight deals from Myrtle Beach to Santa Ana

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Santa Ana that are best for you.

Compare providers for flights from Myrtle Beach to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santa Ana in December.

Best time to book a flight from Myrtle Beach to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Myrtle Beach with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Santa Ana

What is the cheapest month to book a flight from Myrtle Beach to Santa Ana, California?

What is the cheapest time of day to fly from MYR to SNA?

Reviews of airlines servicing Santa Ana

Get a feel of what it's like to fly with American Airlines from Myrtle Beach to Santa Ana by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Myrtle Beach to Santa Ana, California?

What is the cheapest airline to fly from Myrtle Beach to Santa Ana, California round-trip?

Can I find deals for flights from Myrtle Beach to Santa Ana that include hotel bookings?

How can I find direct flights from Myrtle Beach to Santa Ana?

Can I find deals for business class flights from Myrtle Beach to Santa Ana?

What is the cheapest month to book a flight from Myrtle Beach to Santa Ana, California?

Traveling to a place near Santa Ana?

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Alternative routes for Myrtle Beach to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Myrtle Beach to Santa Ana

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Cheapest flights from Myrtle Beach to Santa Ana
Explore the most affordable flight options available from Myrtle Beach to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.