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Santa Ana

$164+ Cheap flights from Myrtle Beach to Santa Ana, CA (MYR - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SNA
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Santa Ana

Cheapest flights from Myrtle Beach to Santa Ana
Explore the most affordable flight options available from Myrtle Beach to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:17 pm
MYR
-
SNA
1 stop9h 00m
American Airlines
Sat 2/149:23 am
SNA
-
MYR
2 stops11h 32m
American Airlines
Deal found 1/27$364
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/244:00 pm
MYR
-
SNA
1 stop7h 10m
Delta
Wed 3/1111:56 am
SNA
-
MYR
1 stop9h 08m
Delta
Deal found 1/26$374
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:26 am
MYR
-
SNA
2 stops12h 05m
American Airlines
Wed 3/117:48 pm
SNA
-
MYR
2 stops9h 44m
American Airlines
Deal found 1/26$385
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/125:18 pm
MYR
-
SNA
1 stop8h 29m
American Airlines
Fri 2/137:48 pm
SNA
-
MYR
2 stops9h 32m
American Airlines
Deal found 1/26$411
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:55 pm
MYR
-
SNA
1 stop10h 19m
American Airlines
Sat 5/167:45 am
SNA
-
MYR
1 stop9h 47m
American Airlines
Deal found 1/28$412
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:40 pm
MYR
-
SNA
1 stop6h 56m
Delta
Mon 5/119:20 pm
SNA
-
MYR
2 stops11h 36m
Delta
Deal found 1/27$423
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:31 pm
MYR
-
SNA
3 stops28h 26m
Spirit Airlines
Mon 5/114:37 pm
SNA
-
MYR
2 stops14h 05m
Spirit Airlines
Deal found 1/27$432
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:57 pm
MYR
-
SNA
1 stop10h 17m
American Airlines
Mon 5/117:20 pm
SNA
-
MYR
2 stops11h 25m
American Airlines
Deal found 1/27$433

Find flight deals from Myrtle Beach to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$364
(American Airlines)

One-way from

$164
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$459
Provider with most accurate pricing for Myrtle Beach Intl-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Myrtle Beach Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Myrtle Beach Intl to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($25 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santa Ana that are best for you.

Fly from

Myrtle Beach

Fly to

Santa Ana

Route

Depart

Return

Price

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Fri 2/13

3:17 pm-9:17 pm

1 stop9h 00m

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

9:23 am-11:55 pm

2 stops11h 32m

$364

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 2/24

4:00 pm-8:10 pm

1 stop7h 10m

Santa Ana J. Wayne/Orange Cnty

Wed 3/11

11:56 am-12:04 am

1 stop9h 08m

$374

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Tue 2/24

10:26 am-7:31 pm

2 stops12h 05m

Santa Ana J. Wayne/Orange Cnty

Wed 3/11

7:48 pm-8:32 am

2 stops9h 44m

$385

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Thu 2/12

5:18 pm-10:47 pm

1 stop8h 29m

Santa Ana J. Wayne/Orange Cnty

Fri 2/13

7:48 pm-8:20 am

2 stops9h 32m

$411

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 5/9

1:55 pm-9:14 pm

1 stop10h 19m

Santa Ana J. Wayne/Orange Cnty

Sat 5/16

7:45 am-8:32 pm

1 stop9h 47m

$412

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Fri 5/8

3:40 pm-7:36 pm

1 stop6h 56m

Santa Ana J. Wayne/Orange Cnty

Mon 5/11

9:20 pm-11:56 am

2 stops11h 36m

$423

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Fri 2/13

9:09 am-12:25 pm

3 stops30h 16m

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

4:37 pm-8:13 am

2 stops12h 36m

$458

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sun 4/12

6:37 pm-12:22 pm

3 stops44h 45m

$164

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Thu 4/30

3:49 pm-10:14 pm

1 stop9h 25m

$195

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Wed 2/11

11:28 am-8:13 am

3 stops23h 45m

$222

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 12 results
1
2

Compare providers for flights from Myrtle Beach to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santa Ana in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Santa Ana

What is the cheapest month to book a flight from Myrtle Beach to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Santa Ana, California (average of $91). Flying from Myrtle Beach to Santa Ana, California in December is currently the most expensive (average of $272). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with American Airlines from Myrtle Beach to Santa Ana by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,206 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
11,206 reviews
American Airlines
7.2
Good
11,206 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Santa Ana, California?

    Airlines like American Airlines and Delta fly from Myrtle Beach to Santa Ana, California in about 7h 10m. The time it takes to get you to your destination can typically vary by up to 1h 50m. The distance from Myrtle Beach to Santa Ana, California is about 2224 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Myrtle Beach to Santa Ana, California round-trip?

    According to our current data, American Airlines ($312), offers the cheapest pricing from Myrtle Beach to Santa Ana, California.

  • Can I find deals for flights from Myrtle Beach to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santa Ana.

  • Can I find deals for business class flights from Myrtle Beach to Santa Ana?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Santa Ana, California?

    Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Santa Ana, California (average of $91). Flying from Myrtle Beach to Santa Ana, California in December is currently the most expensive (average of $272). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
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Top airline flying from Myrtle Beach to Santa Ana

Discover the top airline that operate flights from Myrtle Beach to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$312Average$498FlexibilityNo cancel feeOn-time71%

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