$57+ Cheap flights from Mesa, AZ to Santa Ana, CA (SNA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SNA
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Santa Ana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Santa Ana J. Wayne/Orange Cnty are usually found in February or January, booked 84 days in advance, depart on a Thursday or Friday and return on a Friday
Cheap flight deals from Mesa to Santa Ana
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to Santa AnaExplore the most affordable flight options available from Mesa to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Mesa to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This Super.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:22 am -
Nonstop1h 23m
Thu 9/179:30 am -
Nonstop1h 24m
Deal found 8/30![Frontier logo]()
$77
This Priceline deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:33 am -
Nonstop1h 24m
Thu 10/222:53 pm -
Nonstop1h 24m
Deal found 8/30![Frontier logo]()
$84
This Super.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:22 am -
Nonstop1h 23m
Mon 9/289:30 am -
Nonstop1h 24m
Deal found 9/2![Frontier logo]()
$85
This Super.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:22 am -
Nonstop1h 23m
Sun 9/139:30 am -
Nonstop1h 24m
Deal found 8/30![Frontier logo]()
$87
This Priceline deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:33 am -
Nonstop1h 24m
Thu 10/222:53 pm -
Nonstop1h 24m
Deal found 8/31![Frontier logo]()
$95
This Super.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:22 am -
Nonstop1h 23m
Mon 10/59:30 am -
Nonstop1h 24m
Deal found 8/31![Frontier logo]()
$97
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:22 am -
Nonstop1h 23m
Mon 9/289:30 am -
Nonstop1h 24m
Deal found 9/1![Frontier logo]()
$99
Best flights from Mesa to Santa AnaDiscover carefully curated flight deals from Mesa to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Mesa to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 am -
1 stop4h 55m
Wed 11/1111:45 am -
1 stop6h 00m
Deal found 8/31![Southwest logo]()
$237
This Alaska Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:38 am -
2 stops11h 03m
Sat 10/1711:50 am -
2 stops8h 51m
Deal found 9/1![Alaska Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:31 pm -
1 stop5h 48m
Sat 10/311:09 pm -
1 stop5h 46m
Deal found 8/30![United Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:50 am -
1 stop3h 05m
Fri 12/41:05 pm -
1 stop5h 00m
Deal found 8/29![Southwest logo]()
$331
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:50 pm -
Nonstop1h 20m
Sun 11/297:45 am -
Nonstop1h 30m
Deal found 9/1![Southwest logo]()
$344
This Alaska Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:01 am -
2 stops16h 28m
Tue 12/156:45 am -
2 stops11h 37m
Deal found 9/1![Alaska Airlines logo]()
$399
This Alaska Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:49 pm -
2 stops15h 27m
Tue 10/67:31 pm -
2 stops19h 29m
Deal found 8/31![Alaska Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:00 am -
1 stop5h 01m
Thu 12/1011:30 am -
1 stop5h 02m
Deal found 8/31![United Airlines logo]()
$491
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:30 am -
1 stop4h 25m
Wed 9/164:55 pm -
Nonstop1h 20m
Deal found 8/31![Southwest logo]()
$469
Last-minute flights from Mesa to Santa AnaDiscover last-minute flight deals from Mesa to Santa Ana. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Santa Ana. Data last updated September 2, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:22 am -
Nonstop1h 23m
Thu 9/179:30 am -
Nonstop1h 24m
Deal found 8/30![Frontier logo]()
$77
This Super.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:22 am -
Nonstop1h 23m
Sun 9/139:30 am -
Nonstop1h 24m
Deal found 8/30![Frontier logo]()
$87
This CheapOair deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:22 am -
Nonstop1h 23m
Mon 9/284:35 pm -
1 stop6h 12m
Deal found 9/2![Frontier logo]()
$89
This Super.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:22 am -
Nonstop1h 23m
Mon 9/289:30 am -
Nonstop1h 24m
Deal found 9/2![Frontier logo]()
$85
This Super.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:22 am -
Nonstop1h 23m
Mon 10/59:30 am -
Nonstop1h 24m
Deal found 8/31![Frontier logo]()
$97
This Priceline deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:33 am -
Nonstop1h 24m
Thu 10/222:53 pm -
Nonstop1h 24m
Deal found 8/30![Frontier logo]()
$84
This Priceline deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:33 am -
Nonstop1h 24m
Thu 10/222:53 pm -
Nonstop1h 24m
Deal found 8/31![Frontier logo]()
$95
One-way flights from Mesa to Santa AnaSearch for one-way flight options from Mesa to Santa Ana. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Mesa to Santa Ana. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:22 am -
Nonstop1h 23m
Deal found 9/1![Frontier logo]()
$57
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:40 pm -
Nonstop1h 22m
Deal found 9/1![Frontier logo]()
$58
This Super.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:45 pm -
Nonstop1h 23m
Deal found 8/30![Frontier logo]()
$61
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:54 pm -
Nonstop1h 22m
Deal found 9/1![Frontier logo]()
$68
This CheapOair deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:00 am -
1 stop9h 15m
Deal found 9/2![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:45 pm -
Nonstop1h 23m
Deal found 8/28![Frontier logo]()
$73
This Super.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:22 am -
Nonstop1h 23m
Deal found 9/2![Frontier logo]()
$74
This Mytrip deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Fri 9/257:22 am -
Nonstop1h 23m
Deal found 8/29![Frontier logo]()
$75
This Super.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:22 am -
Nonstop1h 23m
Deal found 8/30![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:37 am -
2 stops29h 38m
Deal found 9/1![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop26h 49m
Deal found 8/31![Frontier logo]()
$81
Find flight deals from Mesa to Santa Ana
Keep the following information in mind while searching for Mesa to Santa Ana flight deals. Data was last updated September 2, 2026.
Round-trip from | $84 (Priceline) |
|---|---|
One-way from | $57 (Kiwi.com) |
Popular in | May |
Cheapest in | February |
Average price | $179 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Mesa to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Wed 11/11
6:05 am-10:00 am
1 stop4h 55m
Santa Ana J. Wayne/Orange Cnty
Wed 11/11
11:45 am-6:45 pm
1 stop6h 00m
$237
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Tue 12/1
6:50 am-8:55 am
1 stop3h 05m
Santa Ana J. Wayne/Orange Cnty
Fri 12/4
1:05 pm-7:05 pm
1 stop5h 00m
$331
Quickest round-trip
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Thu 11/26
12:50 pm-1:10 pm
Nonstop1h 20m
Santa Ana J. Wayne/Orange Cnty
Sun 11/29
7:45 am-10:15 am
Nonstop1h 30m
$344
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Thu 10/15
7:38 am-6:41 pm
2 stops11h 03m
Santa Ana J. Wayne/Orange Cnty
Sat 10/17
11:50 am-8:41 pm
2 stops8h 51m
$393
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Mon 12/14
7:01 am-10:29 pm
2 stops16h 28m
Santa Ana J. Wayne/Orange Cnty
Tue 12/15
6:45 am-7:22 pm
2 stops11h 37m
$399
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Fri 10/30
3:31 pm-9:19 pm
1 stop5h 48m
Santa Ana J. Wayne/Orange Cnty
Sat 10/31
1:09 pm-6:55 pm
1 stop5h 46m
$411
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Fri 9/25
7:49 pm-11:16 am
2 stops15h 27m
Santa Ana J. Wayne/Orange Cnty
Tue 10/6
7:31 pm-3:00 pm
2 stops19h 29m
$443
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Tue 9/15
7:30 am-11:55 am
1 stop4h 25m
Santa Ana J. Wayne/Orange Cnty
Wed 9/16
4:55 pm-6:15 pm
Nonstop1h 20m
$469
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Tue 12/8
8:00 am-12:01 pm
1 stop5h 01m
Santa Ana J. Wayne/Orange Cnty
Thu 12/10
11:30 am-5:32 pm
1 stop5h 02m
$491
Cheapest one-way
Quickest one-way
PhoenixSanta Ana
PHX Phoenix Sky Harbor Intl - SNA Santa Ana J. Wayne/Orange Cnty
PHXSNA
Phoenix Sky Harbor Intl
Mon 10/26
8:55 pm-10:15 pm
Nonstop1h 20m
$109
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Mesa to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Mesa with our price prediction graph.
PHX-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Santa Ana
MS9-SNA
PHX-SNA
What is the cheapest time of day to fly from MS9 to SNA?
Find hourly flight availability from Mesa to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 2, 2026.
It’s typically best to fly out from Mesa to Santa Ana, California in the afternoon. Doing so could potentially save you 70% on the flight price compared to flying in the morning, which is usually more expensive.
Weekly flight availability from Mesa to Santa Ana, California
Explore weekly flight availability from Mesa to Santa Ana. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 2, 2026.
The most flights from MS9 to SNA are scheduled on a Monday (18 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (4 on average).
How much does it cost to fly round-trip from Mesa to Santa Ana, California?
Airfare is below average for this route at the moment.
Mesa to Santa Ana, California flights typically cost between $123 and $257 in October.The cheapest round-trip price found within the last 5 days was $80 on Frontier (Oct 1-Oct 5).
What is the cheapest day to fly from Mesa to Santa Ana, California?
Use this chart to determine the cheapest time to fly round-trip from Mesa to Santa Ana. Price data was last updated on August 29, 2026.
Travelers seeking maximum savings on their Mesa to Santa Ana, California flight should consider departing on Friday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated September 2, 2026.
Peruse reviews from past customers who have flown with Southwest,Alaska Airlines, andAmerican Airlines from Mesa to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Mesa to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santa Ana?
Book flights to Santa Ana if you plan to visit one of these locationsTustin
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Mesa and Santa Ana flights
Browse other Mesa and Santa Ana flight options. Last updated on September 2, 2026.
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Explore flights to Santa Ana departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Mesa to Santa Ana flights
Consider these flights traveling from Mesa to Santa Ana.
Top 5 airlines flying from Mesa to Santa Ana
Discover the top 5 airlines that operate flights from Mesa to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$56 | Average$133 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$77 | Average$94 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$139 | Average$292 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$361 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$390 | Average$529 | FlexibilityNo cancel fee | On-time75% |