What are the cheapest airlines flying from Santiago de los Caballeros to San Francisco round-trip?

According to our current data, JetBlue ($635), Delta ($671), and American Airlines ($690) offers the cheapest pricing from Santiago de los Caballeros to San Francisco.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

How can I find direct flights from Santiago de los Caballeros to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago de los Caballeros to San Francisco.

Can I find deals for business class flights from Santiago de los Caballeros to San Francisco?

Yes. Cheapflights offers flight deals from Santiago de los Caballeros to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$568+ Flights from Santiago de los Caballeros to San Francisco

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Cheap flight deals from Santiago de los Caballeros to San Francisco

Round-trip from	$635 (JetBlue)
One-way from	$568 (American Airlines)

From Santiago de los Caballeros to San Francisco

Search Deals

One-way flight from Santiago de los Caballeros to San Francisco

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Find flight deals from Santiago de los Caballeros to San Francisco

Cheapest flights from Santiago de los Caballeros to San Francisco
Explore the most affordable flight options available from Santiago de los Caballeros to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Fri 9/126:20 amSTI - SFO

1 stop17h 43mJetBlue

Fri 9/199:00 pmSFO - STI

1 stop14h 13mJetBlue

Deal found 7/29

$635

Fri 12/56:45 amSTI - SFO

1 stop18h 19mDelta

Mon 1/510:45 pmSFO - STI

1 stop16h 01mDelta

Deal found 7/28

$671

Thu 9/111:29 pmSTI - SFO

1 stop12h 25mAmerican Airlines

Thu 9/1811:58 pmSFO - STI

1 stop9h 29mAmerican Airlines

Deal found 7/28

$690

Fri 12/196:18 pmSTI - SFO

3 stops26h 36mMultiple Airlines

Sat 1/36:12 pmSFO - STI

2 stops18h 54mMultiple Airlines

Deal found 7/27

$1,123

Best flights from Santiago de los Caballeros to San Francisco
Discover carefully curated flight deals from Santiago de los Caballeros to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2025.

Fri 9/126:20 amSTI - SFO

1 stop17h 43mJetBlue

Fri 9/199:00 pmSFO - STI

1 stop14h 13mJetBlue

Deal found 7/29

$635

Fri 12/56:45 amSTI - SFO

1 stop18h 19mDelta

Mon 1/510:45 pmSFO - STI

1 stop16h 01mDelta

Deal found 7/28

$671

Thu 9/111:29 pmSTI - SFO

1 stop12h 25mAmerican Airlines

Thu 9/1811:58 pmSFO - STI

1 stop9h 29mAmerican Airlines

Deal found 7/28

$690

Fri 12/196:18 pmSTI - SFO

3 stops26h 36mMultiple Airlines

Sat 1/36:12 pmSFO - STI

2 stops18h 54mMultiple Airlines

Deal found 7/27

$1,123

Last-minute flights from Santiago de los Caballeros to San Francisco
Discover last-minute flight deals from Santiago de los Caballeros to San Francisco. Data last updated July 29, 2025 and is based on user searches.

Tue 8/197:00 amSTI - SFO

1 stop18h 59mAmerican Airlines

Tue 8/2611:59 pmSFO - STI

1 stop9h 32mAmerican Airlines

Deal found 7/26

$744

One-way flights from Santiago de los Caballeros to San Francisco
Search for one-way flight options from Santiago de los Caballeros to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 29, 2025.

Sun 8/107:00 amSTI - SFO

2 stops18h 40mAmerican Airlines

Deal found 7/27

$568

Sun 8/1010:38 pmSTI - SFO

1 stop14h 00mJetBlue

Deal found 7/28

$664

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago de los Caballeros to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 9/12

6:20 am-9:03 pm

1 stop17h 43m

San Francisco

Fri 9/19

9:00 pm-2:13 pm

1 stop14h 13m

$635

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 12/5

6:45 am-9:04 pm

1 stop18h 19m

San Francisco

Mon 1/5

10:45 pm-6:46 pm

1 stop16h 01m

$671

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 9/11

1:29 pm-10:54 pm

1 stop12h 25m

San Francisco

Thu 9/18

11:58 pm-12:27 pm

1 stop9h 29m

$690

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 12/19

6:18 pm-4:54 pm

3 stops26h 36m

San Francisco

Sat 1/3

6:12 pm-5:06 pm

2 stops18h 54m

$1,123

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Sun 8/10

7:00 am-10:40 pm

2 stops18h 40m

$568

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Sun 8/10

10:38 pm-9:38 am

1 stop14h 00m

$664

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Santiago de los Caballeros to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago de los Caballeros with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago de los Caballeros to San Francisco

What is the cheapest month to book a flight from Santiago de los Caballeros to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Santiago de los Caballeros to San Francisco (average of $276). Flying from Santiago de los Caballeros to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STI to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago de los Caballeros to San Francisco as you normally would.

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Delta, JetBlue, and American Airlines from Santiago de los Caballeros to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,979 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

JetBlue

7.3

Good

2,913 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Santiago de los Caballeros to San Francisco round-trip?
According to our current data, JetBlue ($635), Delta ($671), and American Airlines ($690) offers the cheapest pricing from Santiago de los Caballeros to San Francisco.
Can I find deals for flights from Santiago de los Caballeros to San Francisco that include hotel bookings?
Yes. In addition to deals on Santiago de los Caballeros to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago de los Caballeros to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago de los Caballeros to San Francisco.
Can I find deals for business class flights from Santiago de los Caballeros to San Francisco?
Yes. Cheapflights offers flight deals from Santiago de los Caballeros to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago de los Caballeros to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Santiago de los Caballeros to San Francisco (average of $276). Flying from Santiago de los Caballeros to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Mountain View

Santa Cruz

South San Francisco

Livermore

Turlock

Manteca

Antioch

Hollister

Watsonville

Sunnyvale

Newark

Milpitas

Campbell

Foster City

Capitola

Santa Clara

San Leandro

Burlingame

Redwood City

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago de los Caballeros to San Francisco

Top airline flying from Santiago de los Caballeros to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
JetBlue	Cheapest$335	Average$533	FlexibilityNo cancel fee	On-time62%

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$568+ Cheap flights from Santiago de los Caballeros (STI) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago de los Caballeros to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santiago de los Caballeros to San Francisco

Round-trip from

One-way from

Find flight deals from Santiago de los Caballeros to San Francisco

Cheapest flights from Santiago de los Caballeros to San FranciscoExplore the most affordable flight options available from Santiago de los Caballeros to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Explore the most affordable flight options available from Santiago de los Caballeros to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago de los Caballeros to San Francisco that are best for you.

Best time to book a flight from Santiago de los Caballeros to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago de los Caballeros with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santiago de los Caballeros to San Francisco

What is the cheapest month to book a flight from Santiago de los Caballeros to San Francisco?

What is the cheapest time of day to fly from STI to SFO?

Find hourly flight availability from Santiago de los Caballeros to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

Reviews of airlines servicing San Francisco

Related info for your journey

Find useful and relevant information for your journey from Santiago de los Caballeros to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santiago de los Caballeros to San Francisco round-trip?

Can I find deals for flights from Santiago de los Caballeros to San Francisco that include hotel bookings?

How can I find direct flights from Santiago de los Caballeros to San Francisco?

Can I find deals for business class flights from Santiago de los Caballeros to San Francisco?

What is the cheapest month to book a flight from Santiago de los Caballeros to San Francisco?

Traveling to a place near San Francisco?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santiago de los Caballeros to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Santiago de los Caballeros to San Francisco

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Santiago de los Caballeros to San Francisco
Explore the most affordable flight options available from Santiago de los Caballeros to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.