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$386+ Cheap flights from Santiago de los Caballeros (STI) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
STI — SFO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Santiago de los Caballeros to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago de los Caballeros (STI) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$477
(JetBlue)

One-way from

$386
(Kiwi.com)
From Santiago de los Caballeros to San Francisco
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One-way flight from Santiago de los Caballeros to San Francisco
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Find flight deals from Santiago de los Caballeros to San Francisco

Cheapest flights from Santiago de los Caballeros to San Francisco
Explore the most affordable flight options available from Santiago de los Caballeros to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:20 amSTI - SFO
1 stop11h 33mJetBlue
Sat 11/17:00 amSFO - STI
1 stop15h 58mJetBlue
Deal found 9/10$477
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:55 amSTI - SFO
1 stop14h 06mJetBlue
Fri 10/3112:10 pmSFO - STI
1 stop11h 43mJetBlue
Deal found 9/9$480
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/241:14 pmSTI - SFO
2 stops22h 32mAmerican Airlines
Fri 10/3112:27 pmSFO - STI
1 stop20h 46mAmerican Airlines
Deal found 9/9$738
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/251:14 pmSTI - SFO
2 stops22h 31mAmerican Airlines
Sat 11/111:36 pmSFO - STI
2 stops12h 57mAmerican Airlines
Deal found 9/10$744
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/121:14 pmSTI - SFO
1 stop12h 45mAmerican Airlines
Wed 10/2211:59 pmSFO - STI
1 stop9h 14mAmerican Airlines
Deal found 9/9$773
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:36 amSTI - SFO
1 stop16h 54mJetBlue
Sat 1/37:30 amSFO - STI
1 stop21h 56mJetBlue
Deal found 9/10$820
This Expedia deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/113:20 amSTI - SFO
1 stop24h 39mJetBlue
Wed 10/226:00 amSFO - STI
1 stop17h 21mJetBlue
Deal found 9/9$925

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Santiago de los Caballeros to San Francisco that are best for you.

Fly from

Santiago de los Caballeros

Fly to

San Francisco

Route

Depart

Return

Price

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 10/24

3:20 am-11:53 am

1 stop11h 33m

San Francisco

Sat 11/1

7:00 am-1:58 am

1 stop15h 58m

$477

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 10/24

9:55 am-9:01 pm

1 stop14h 06m

San Francisco

Fri 10/31

12:10 pm-2:53 am

1 stop11h 43m

$480

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 10/24

1:14 pm-8:46 am

2 stops22h 32m

San Francisco

Fri 10/31

12:27 pm-12:13 pm

1 stop20h 46m

$738

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Sat 10/25

1:14 pm-8:45 am

2 stops22h 31m

San Francisco

Sat 11/1

11:36 pm-3:33 pm

2 stops12h 57m

$744

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Sun 10/12

1:14 pm-10:59 pm

1 stop12h 45m

San Francisco

Wed 10/22

11:59 pm-12:13 pm

1 stop9h 14m

$773

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Sat 10/11

3:20 am-12:59 am

1 stop24h 39m

San Francisco

Wed 10/22

6:00 am-2:21 am

1 stop17h 21m

$925

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 9/19

12:10 pm-9:09 pm

3 stops35h 59m

$386

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 9/19

1:12 pm-12:59 am

1 stop14h 47m

$467

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Mon 9/15

12:10 pm-9:21 pm

2 stops36h 11m

$606

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Mon 9/15

1:29 pm-1:05 pm

1 stop26h 36m

$734

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Santiago de los Caballeros to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago de los Caballeros with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago de los Caballeros to San Francisco

What is the cheapest month to book a flight from Santiago de los Caballeros to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Santiago de los Caballeros to San Francisco (average of $276). Flying from Santiago de los Caballeros to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STI to SFO?

Find hourly flight availability from Santiago de los Caballeros to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago de los Caballeros to San Francisco as you normally would.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown JetBlue from Santiago de los Caballeros to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
JetBlue
7.2
Good
2,913 reviews

Comfort

7.6

Overall

7.2

Boarding

7.4

Food

6.7

Crew

8.0

Entertainment

7.3

Reviews

1 / 20
10.0
Excellent

JACK,Sep 2025

JFK - MSY

I liked the professional services of the crew. Keep up the good work.
JetBlue
7.2
Good
2,913 reviews
JetBlue
7.2
Good
2,913 reviews

Comfort

7.6

Overall

7.2

Boarding

7.4

Food

6.7

Crew

8.0

Entertainment

7.3

Reviews

1 / 20
10.0
Excellent

JACK,Sep 2025

JFK - MSY

I liked the professional services of the crew. Keep up the good work.

Related info for your journey

Find useful and relevant information for your journey from Santiago de los Caballeros to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago de los Caballeros to San Francisco?

    A quick flight from Santiago de los Caballeros to San Francisco can take about 11h 33m. JetBlue provides one of the quickest options available for as low as $477. The distance from Santiago de los Caballeros to San Francisco is about 3336 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Santiago de los Caballeros to San Francisco round-trip?

    According to our current data, JetBlue ($335), offers the cheapest pricing from Santiago de los Caballeros to San Francisco.

  • Can I find deals for flights from Santiago de los Caballeros to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santiago de los Caballeros to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago de los Caballeros to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago de los Caballeros to San Francisco.

  • Can I find deals for business class flights from Santiago de los Caballeros to San Francisco?

    Yes. Cheapflights offers flight deals from Santiago de los Caballeros to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago de los Caballeros to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Santiago de los Caballeros to San Francisco (average of $276). Flying from Santiago de los Caballeros to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Manteca
Santa Clara
Sunnyvale
Hollister
Vacaville
Foster City
Vallejo
Burlingame
Redwood City
Union City
San Leandro
San Mateo
Lathrop

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Alternative routes for Santiago de los Caballeros to San Francisco

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Top airline flying from Santiago de los Caballeros to San Francisco

Discover the top airline that operate flights from Santiago de los Caballeros to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$335Average$534FlexibilityNo cancel feeOn-time62%

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