$105+ Cheap flights from Mississippi to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SFO
May 28 — Jun 41
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Mississippi to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mississippi to San FranciscoExplore the most affordable flight options available from Mississippi to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Mississippi to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/39:28 pm
MEM
- SFO
1 stop14h 57m
Multiple Airlines
Mon 8/1711:10 am
SFO
- MEM
1 stop7h 31m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$205
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:54 pm
MEM
- SFO
1 stop17h 53m
Frontier
Wed 6/38:56 am
SFO
- MEM
1 stop8h 13m
Frontier
Deal found 4/26![Frontier logo]()
$210
This Frontier deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:59 am
MEM
- SFO
1 stop9h 35m
Frontier
Wed 6/36:00 am
SFO
- MEM
1 stop11h 09m
Frontier
Deal found 4/24![Frontier logo]()
$211
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:59 am
MEM
- SFO
1 stop9h 35m
Frontier
Fri 5/298:56 am
SFO
- MEM
1 stop8h 13m
Frontier
Deal found 4/23![Frontier logo]()
$230
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:51 pm
MEM
- SFO
1 stop23h 05m
Frontier
Wed 5/1310:15 pm
SFO
- MEM
1 stop10h 44m
Frontier
Deal found 4/26![Frontier logo]()
$231
This Frontier deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:54 pm
MEM
- SFO
1 stop6h 29m
Frontier
Mon 6/86:00 am
SFO
- MEM
1 stop11h 09m
Frontier
Deal found 4/27![Frontier logo]()
$250
This Frontier deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:22 pm
MEM
- SFO
1 stop8h 01m
Frontier
Wed 5/1310:15 pm
SFO
- MEM
1 stop10h 44m
Frontier
Deal found 4/27![Frontier logo]()
$252
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:54 pm
MEM
- SFO
1 stop6h 29m
Frontier
Sat 5/910:15 pm
SFO
- MEM
1 stop10h 44m
Frontier
Deal found 4/23![Frontier logo]()
$255
This Frontier deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:59 pm
MEM
- SFO
1 stop6h 28m
Frontier
Mon 6/2910:10 pm
SFO
- MEM
1 stop10h 45m
Frontier
Deal found 4/25![Frontier logo]()
$270
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:27 pm
GPT
- SFO
1 stop6h 46m
American Airlines
Tue 10/65:54 am
SFO
- GPT
1 stop9h 34m
American Airlines
Deal found 4/28![American Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:09 pm
GPT
- SFO
2 stops10h 05m
American Airlines
Tue 11/1012:27 am
SFO
- GPT
1 stop9h 56m
American Airlines
Deal found 4/26![American Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:00 am
BTR
- SFO
1 stop7h 25m
United Airlines
Sun 8/911:59 pm
SFO
- BTR
1 stop6h 47m
United Airlines
Deal found 4/28![United Airlines logo]()
$349
Best flights from Mississippi to San FranciscoDiscover carefully curated flight deals from Mississippi to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Mississippi to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:00 am
BTR
- SFO
1 stop7h 25m
United Airlines
Sun 8/911:59 pm
SFO
- BTR
1 stop6h 47m
United Airlines
Deal found 4/28![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:16 pm
AEX
- SFO
1 stop7h 05m
American Airlines
Mon 9/2811:30 pm
SFO
- AEX
1 stop8h 38m
American Airlines
Deal found 4/27![American Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:00 pm
AEX
- SFO
1 stop9h 02m
Delta
Mon 9/2811:45 pm
SFO
- AEX
1 stop8h 58m
Delta
Deal found 4/25![Delta logo]()
$358
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/113:15 pm
MEM
- SFO
1 stop10h 15m
Southwest
Thu 7/165:10 am
SFO
- MEM
1 stop6h 45m
Southwest
Deal found 4/27![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:43 am
AEX
- SFO
1 stop7h 20m
United Airlines
Tue 6/235:00 am
SFO
- AEX
1 stop7h 50m
United Airlines
Deal found 4/27![United Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:25 am
BTR
- SFO
1 stop9h 06m
Delta
Mon 7/139:56 pm
SFO
- BTR
1 stop9h 43m
Delta
Deal found 4/27![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:43 am
AEX
- SFO
1 stop7h 20m
United Airlines
Wed 6/245:00 am
SFO
- AEX
1 stop7h 50m
United Airlines
Deal found 4/27![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:32 pm
BTR
- SFO
1 stop6h 37m
American Airlines
Tue 5/195:14 am
SFO
- BTR
1 stop9h 09m
American Airlines
Deal found 4/23![American Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:11 am
BTR
- SFO
1 stop7h 34m
Delta
Tue 7/711:59 pm
SFO
- BTR
1 stop7h 40m
Delta
Deal found 4/26![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 am
GPT
- SFO
1 stop7h 15m
Delta
Tue 7/711:59 pm
SFO
- GPT
1 stop7h 20m
Delta
Deal found 4/26![Delta logo]()
$371
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
AEX
- SFO
2 stops8h 22m
American Airlines
Wed 5/1311:59 pm
SFO
- AEX
1 stop7h 38m
American Airlines
Deal found 4/24![American Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:40 am
MEM
- SFO
1 stop6h 25m
Southwest
Sun 7/1210:50 pm
SFO
- MEM
1 stop8h 15m
Southwest
Deal found 4/27![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:55 pm
MOB
- SFO
1 stop9h 04m
United Airlines
Sun 5/247:05 am
SFO
- MOB
1 stop9h 09m
United Airlines
Deal found 4/23![United Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:26 pm
AEX
- SFO
1 stop6h 33m
American Airlines
Tue 5/1210:13 am
SFO
- AEX
2 stops10h 24m
American Airlines
Deal found 4/23![American Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:25 pm
MEM
- SFO
2 stops8h 15m
Southwest
Thu 8/65:10 am
SFO
- MEM
2 stops9h 00m
Southwest
Deal found 4/27![Southwest logo]()
$467
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:15 pm
MOB
- SFO
1 stop9h 47m
Delta
Sat 9/2611:45 pm
SFO
- MOB
1 stop6h 39m
Delta
Deal found 4/23![Delta logo]()
$394
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:15 pm
BTR
- SFO
1 stop6h 37m
United Airlines
Sat 5/1612:45 am
SFO
- BTR
1 stop8h 31m
United Airlines
Deal found 4/25![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/124:10 pm
MEM
- SFO
1 stop10h 00m
Southwest
Sat 6/206:10 am
SFO
- MEM
2 stops12h 20m
Southwest
Deal found 4/25![Southwest logo]()
$472
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:25 pm
MOB
- SFO
1 stop7h 24m
Delta
Tue 7/72:00 pm
SFO
- MOB
1 stop7h 25m
Delta
Deal found 4/26![Delta logo]()
$394
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:50 pm
GPT
- SFO
1 stop6h 58m
American Airlines
Mon 6/811:49 pm
SFO
- GPT
1 stop8h 25m
American Airlines
Deal found 4/24![American Airlines logo]()
$441
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:09 pm
BTR
- SFO
1 stop8h 06m
United Airlines
Sat 6/612:45 am
SFO
- BTR
1 stop6h 01m
United Airlines
Deal found 4/25![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:37 pm
BTR
- SFO
1 stop7h 28m
Delta
Mon 6/111:55 pm
SFO
- BTR
1 stop7h 50m
Delta
Deal found 4/23![Delta logo]()
$394
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:25 am
JAN
- SFO
1 stop10h 30m
Southwest
Mon 6/159:25 am
SFO
- JAN
2 stops10h 30m
Southwest
Deal found 4/28![Southwest logo]()
$478
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:10 am
GPT
- SFO
2 stops10h 10m
American Airlines
Sat 5/1611:59 pm
SFO
- GPT
1 stop8h 34m
American Airlines
Deal found 4/27![American Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:00 am
MOB
- SFO
1 stop7h 18m
United Airlines
Fri 5/1512:45 am
SFO
- MOB
1 stop8h 50m
United Airlines
Deal found 4/26![United Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:25 pm
MEM
- SFO
2 stops8h 25m
Southwest
Sat 6/207:05 am
SFO
- MEM
2 stops11h 25m
Southwest
Deal found 4/23![Southwest logo]()
$483
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:10 pm
AEX
- SFO
1 stop8h 55m
Delta
Tue 5/1211:41 am
SFO
- AEX
1 stop7h 34m
Delta
Deal found 4/23![Delta logo]()
$408
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:03 pm
GPT
- SFO
1 stop8h 51m
American Airlines
Mon 5/1811:59 pm
SFO
- GPT
1 stop8h 34m
American Airlines
Deal found 4/25![American Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
MOB
- SFO
1 stop7h 18m
United Airlines
Wed 5/138:55 am
SFO
- MOB
1 stop7h 10m
United Airlines
Deal found 4/23![United Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:30 am
JAN
- SFO
2 stops8h 05m
Southwest
Tue 5/1910:30 am
SFO
- JAN
2 stops7h 50m
Southwest
Deal found 4/27![Southwest logo]()
$495
Last-minute flights from Mississippi to San FranciscoDiscover last-minute flight deals from Mississippi to San Francisco. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to San Francisco. Data last updated April 28, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:36 pm
MEM
- SFO
1 stop9h 51m
Frontier
Sun 5/36:00 am
SFO
- MEM
1 stop10h 57m
Frontier
Deal found 4/23![Frontier logo]()
$305
This Frontier deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:22 pm
MEM
- SFO
1 stop8h 01m
Frontier
Wed 5/1310:15 pm
SFO
- MEM
1 stop10h 44m
Frontier
Deal found 4/27![Frontier logo]()
$252
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:54 pm
MEM
- SFO
1 stop6h 29m
Frontier
Sat 5/910:15 pm
SFO
- MEM
1 stop10h 44m
Frontier
Deal found 4/23![Frontier logo]()
$255
This Frontier deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:54 pm
MEM
- SFO
1 stop6h 29m
Frontier
Mon 5/116:00 am
SFO
- MEM
1 stop11h 09m
Frontier
Deal found 4/24![Frontier logo]()
$281
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:51 pm
MEM
- SFO
1 stop23h 05m
Frontier
Wed 5/1310:15 pm
SFO
- MEM
1 stop10h 44m
Frontier
Deal found 4/26![Frontier logo]()
$231
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:35 am
BTR
- SFO
2 stops9h 05m
American Airlines
Wed 5/208:00 am
SFO
- BTR
1 stop8h 02m
American Airlines
Deal found 4/28![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:55 pm
MOB
- SFO
1 stop9h 04m
United Airlines
Sun 5/247:05 am
SFO
- MOB
1 stop9h 09m
United Airlines
Deal found 4/23![United Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:00 am
BTR
- SFO
1 stop9h 18m
United Airlines
Tue 8/1112:45 am
SFO
- BTR
1 stop5h 58m
United Airlines
Deal found 4/27![United Airlines logo]()
$394
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:54 pm
MEM
- SFO
1 stop17h 53m
Frontier
Wed 6/38:56 am
SFO
- MEM
1 stop8h 13m
Frontier
Deal found 4/26![Frontier logo]()
$210
This Frontier deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:59 am
MEM
- SFO
1 stop9h 35m
Frontier
Wed 6/36:00 am
SFO
- MEM
1 stop11h 09m
Frontier
Deal found 4/24![Frontier logo]()
$211
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:59 am
MEM
- SFO
1 stop9h 35m
Frontier
Fri 5/298:56 am
SFO
- MEM
1 stop8h 13m
Frontier
Deal found 4/23![Frontier logo]()
$230
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:16 pm
BTR
- SFO
1 stop7h 05m
American Airlines
Sun 5/3112:26 am
SFO
- BTR
1 stop8h 34m
American Airlines
Deal found 4/26![American Airlines logo]()
$369
One-way flights from Mississippi to San FranciscoSearch for one-way flight options from Mississippi to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Mississippi to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Frontier deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:59 am
MEM
- SFO
1 stop9h 35m
Frontier
Deal found 4/24![Frontier logo]()
$105
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:59 pm
MEM
- SFO
1 stop6h 28m
Frontier
Deal found 4/28![Frontier logo]()
$125
This Priceline deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:22 pm
MEM
- SFO
1 stop8h 01m
Frontier
Deal found 4/26![Frontier logo]()
$126
This Expedia deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:51 pm
MEM
- SFO
1 stop23h 05m
Frontier
Deal found 4/27![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:54 pm
MEM
- SFO
1 stop30h 29m
Frontier
Deal found 4/24![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:53 pm
MEM
- SFO
2 stops26h 02m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/139:28 pm
MEM
- SFO
1 stop24h 25m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$144
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:51 am
MEM
- SFO
1 stop9h 35m
Frontier
Deal found 4/28![Frontier logo]()
$145
This Travelocity deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:51 pm
MEM
- SFO
1 stop17h 45m
Frontier
Deal found 4/25![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:54 pm
MEM
- SFO
2 stops48h 03m
Frontier
Deal found 4/24![Frontier logo]()
$153
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:29 pm
JAN
- SFO
1 stop7h 19m
American Airlines
Deal found 4/28![American Airlines logo]()
$200
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:40 pm
BTR
- SFO
1 stop9h 41m
Delta
Deal found 4/25![Delta logo]()
$215
Find flight deals from Mississippi to San Francisco
Keep the following information in mind while searching for Mississippi to San Francisco flight deals. Data was last updated April 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $205 (Kiwi.com) |
One-way from | $105 (Frontier) |
Popular in | May |
Cheapest in | October |
Average price | $526 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Mississippi to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Baton RougeSan Francisco
BTR - SFO
BTRSFO
Baton Rouge Ryan
Thu 8/6
5:00 am-10:25 am
1 stop7h 25m
San Francisco
Sun 8/9
11:59 pm-8:46 am
1 stop6h 47m
$349
AlexandriaSan Francisco
AEX - SFO
AEXSFO
Alexandria
Thu 9/24
5:16 pm-10:21 pm
1 stop7h 05m
San Francisco
Mon 9/28
11:30 pm-10:08 am
1 stop8h 38m
$358
AlexandriaSan Francisco
AEX - SFO
AEXSFO
Alexandria
Thu 9/24
5:00 pm-12:02 am
1 stop9h 02m
San Francisco
Mon 9/28
11:45 pm-10:43 am
1 stop8h 58m
$358
AlexandriaSan Francisco
AEX - SFO
AEXSFO
Alexandria
Tue 6/9
9:43 am-3:03 pm
1 stop7h 20m
San Francisco
Tue 6/23
5:00 am-2:50 pm
1 stop7h 50m
$358
AlexandriaSan Francisco
AEX - SFO
AEXSFO
Alexandria
Tue 6/9
9:43 am-3:03 pm
1 stop7h 20m
San Francisco
Wed 6/24
5:00 am-2:50 pm
1 stop7h 50m
$358
Baton RougeSan Francisco
BTR - SFO
BTRSFO
Baton Rouge Ryan
Thu 7/9
10:25 am-5:31 pm
1 stop9h 06m
San Francisco
Mon 7/13
9:56 pm-9:39 am
1 stop9h 43m
$369
Baton RougeSan Francisco
BTR - SFO
BTRSFO
Baton Rouge Ryan
Tue 6/16
6:11 am-11:45 am
1 stop7h 34m
San Francisco
Tue 7/7
11:59 pm-9:39 am
1 stop7h 40m
$369
GulfportSan Francisco
GPT - SFO
GPTSFO
Gulfport Biloxi Regional
Tue 6/16
6:30 am-11:45 am
1 stop7h 15m
San Francisco
Tue 7/7
11:59 pm-9:19 am
1 stop7h 20m
$371
Baton RougeSan Francisco
BTR - SFO
BTRSFO
Baton Rouge Ryan
Wed 5/13
6:32 pm-11:09 pm
1 stop6h 37m
San Francisco
Tue 5/19
5:14 am-4:23 pm
1 stop9h 09m
$394
MobileSan Francisco
MOB - SFO
MOBSFO
Mobile
Wed 5/13
4:55 pm-11:59 pm
1 stop9h 04m
San Francisco
Sun 5/24
7:05 am-6:14 pm
1 stop9h 09m
$394
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Mississippi to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mississippi with our price prediction graph.
MEM-SFO
BTR-SFO
MOB-SFO
GPT-SFO
JAN-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to San Francisco
USMS-SFO
MEM-SFO
BTR-SFO
MOB-SFO
GPT-SFO
What is the cheapest month to book a flight from Mississippi to San Francisco?
Currently, August is the cheapest month in which you can book a flight from Mississippi to San Francisco (average of $192). Flying from Mississippi to San Francisco in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Mississippi to San Francisco?
Related info for your journey
Find useful and relevant information for your journey from Mississippi to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Emeryville
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
San Francisco flight routes
Top destinations
Alternative routes for Mississippi to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to San Francisco by cabin class
Find flights from Mississippi to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and San Francisco flights
Browse other Mississippi and San Francisco flight options. Last updated on April 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
Mississippi to San Francisco flights
Consider these flights traveling from Mississippi to San Francisco.
Top 2 airlines flying from Mississippi to San Francisco
Discover the top 2 airlines that operate flights from Mississippi to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$260 | Average$454 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$288 | Average$456 | FlexibilityNo cancel fee | On-time71% |