$79+ Cheap flights from Mesa, AZ to San Francisco (SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SFO
Oct 19 — Oct 261
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Mesa to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to San Francisco are usually found in February or January, booked 60 days in advance, depart on a Friday or Thursday and return on a Saturday
Cheap flight deals from Mesa to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to San FranciscoExplore the most affordable flight options available from Mesa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from Mesa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:30 am -
1 stop6h 50m
Sun 11/14:57 pm -
1 stop28h 08m
Deal found 9/18![Frontier logo]()
$111
This Expedia deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:38 am -
1 stop5h 03m
Sat 10/245:48 pm -
Nonstop2h 12m
Deal found 9/19![Multiple Airlines logo]()
$112
This Priceline deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:45 pm -
Nonstop2h 17m
Sat 11/72:44 pm -
1 stop3h 56m
Deal found 9/18![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:16 am -
1 stop6h 09m
Tue 10/133:11 pm -
1 stop5h 04m
Deal found 9/18![Frontier logo]()
$114
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:16 am -
2 stops12h 22m
Wed 11/49:14 am -
1 stop8h 12m
Deal found 9/18![Frontier logo]()
$115
This Expedia deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 am -
Nonstop2h 16m
Fri 10/235:48 pm -
Nonstop2h 12m
Deal found 9/18![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:45 pm -
Nonstop2h 17m
Sat 11/72:44 pm -
1 stop3h 56m
Deal found 9/17![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:21 am -
Nonstop2h 16m
Tue 10/207:25 pm -
1 stop22h 31m
Deal found 9/16![Frontier logo]()
$118
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:22 pm -
Nonstop2h 14m
Thu 10/87:59 pm -
1 stop16h 18m
Deal found 9/17![Frontier logo]()
$119
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 am -
Nonstop2h 16m
Sat 10/1711:22 am -
1 stop4h 06m
Deal found 9/16![Frontier logo]()
$120
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 am -
Nonstop2h 16m
Thu 10/2211:22 am -
1 stop4h 06m
Deal found 9/16![Frontier logo]()
$121
This deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:21 am -
1 stop4h 04m
Wed 10/79:00 am -
1 stop5h 16m
Deal found 9/15![Frontier logo]()
$122
Best flights from Mesa to San FranciscoDiscover carefully curated flight deals from Mesa to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from Mesa to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:20 am -
Nonstop2h 10m
Wed 11/45:05 am -
Nonstop1h 55m
Deal found 9/16![Southwest logo]()
$127
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:00 am -
Nonstop2h 08m
Sat 10/2412:25 pm -
Nonstop2h 10m
Deal found 9/18![United Airlines logo]()
$137
This Alaska Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:42 pm -
1 stop4h 51m
Wed 10/284:43 pm -
1 stop3h 58m
Deal found 9/16![Alaska Airlines logo]()
$157
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:30 am -
Nonstop2h 13m
Mon 12/1410:05 am -
Nonstop2h 06m
Deal found 9/18![United Airlines logo]()
$157
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:50 am -
Nonstop2h 00m
Sat 11/75:50 am -
Nonstop2h 05m
Deal found 9/18![Southwest logo]()
$157
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:46 am -
Nonstop2h 08m
Mon 10/197:05 pm -
Nonstop2h 10m
Deal found 9/16![United Airlines logo]()
$157
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:20 pm -
Nonstop2h 00m
Mon 11/25:15 am -
Nonstop2h 00m
Deal found 9/17![Southwest logo]()
$163
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:49 am -
Nonstop2h 08m
Sun 10/257:05 am -
Nonstop2h 01m
Deal found 9/18![United Airlines logo]()
$157
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am -
1 stop6h 27m
Sat 12/56:54 pm -
Nonstop2h 05m
Deal found 9/16![United Airlines logo]()
$167
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:35 am -
2 stops5h 50m
Mon 11/1610:55 am -
1 stop6h 40m
Deal found 9/17![Southwest logo]()
$192
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:05 am -
2 stops7h 05m
Sat 10/2412:55 pm -
2 stops6h 00m
Deal found 9/17![Southwest logo]()
$227
Last-minute flights from Mesa to San FranciscoDiscover last-minute flight deals from Mesa to San Francisco. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to San Francisco. Data last updated September 19, 2026 and is based on user searches.
This deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:21 am -
1 stop4h 04m
Wed 10/79:00 am -
1 stop5h 16m
Deal found 9/15![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:14 pm -
1 stop16h 08m
Sat 10/105:48 pm -
Nonstop2h 12m
Deal found 9/16![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:16 am -
1 stop6h 09m
Tue 10/133:11 pm -
1 stop5h 04m
Deal found 9/18![Frontier logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:21 am -
Nonstop2h 16m
Sat 10/105:48 pm -
Nonstop2h 12m
Deal found 9/17![Frontier logo]()
$117
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 am -
Nonstop2h 16m
Mon 10/195:48 pm -
Nonstop2h 12m
Deal found 9/18![Frontier logo]()
$116
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 am -
Nonstop2h 16m
Sat 10/1711:22 am -
1 stop4h 06m
Deal found 9/16![Frontier logo]()
$120
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 am -
Nonstop2h 16m
Thu 10/2211:22 am -
1 stop4h 06m
Deal found 9/16![Frontier logo]()
$121
This Expedia deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:38 am -
1 stop5h 03m
Sat 10/245:48 pm -
Nonstop2h 12m
Deal found 9/19![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:21 am -
Nonstop2h 16m
Tue 10/207:25 pm -
1 stop22h 31m
Deal found 9/16![Frontier logo]()
$118
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:16 am -
2 stops12h 22m
Wed 11/49:14 am -
1 stop8h 12m
Deal found 9/18![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:30 am -
1 stop6h 50m
Sun 11/14:57 pm -
1 stop28h 08m
Deal found 9/18![Frontier logo]()
$111
This Priceline deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:45 pm -
Nonstop2h 17m
Sat 11/72:44 pm -
1 stop3h 56m
Deal found 9/18![Multiple Airlines logo]()
$113
One-way flights from Mesa to San FranciscoSearch for one-way flight options from Mesa to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from Mesa to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This Super.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:21 am -
Nonstop2h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:33 pm -
1 stop24h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$81
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:45 pm -
Nonstop2h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:52 am -
1 stop27h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:00 pm -
1 stop19h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$84
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:18 pm -
1 stop5h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:12 pm -
1 stop27h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$87
This Super.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:44 am -
1 stop3h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Frontier logo]()
$88
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:45 pm -
Nonstop2h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:45 am -
1 stop11h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Frontier logo]()
$90
Find flight deals from Mesa to San Francisco
Keep the following information in mind while searching for Mesa to San Francisco flight deals. Data was last updated September 19, 2026.
Round-trip from | $111 (Kiwi.com) |
|---|---|
One-way from | $79 (Super.com) |
Popular in | September |
Cheapest in | February |
Average price | $272 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from Mesa to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Mon 10/5
10:35 pm-12:40 am
Nonstop2h 05m
San Francisco
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$102
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Mon 10/26
10:35 pm-12:40 am
Nonstop2h 05m
San Francisco
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$102
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Sat 12/12
9:30 am-10:43 am
Nonstop2h 13m
San Francisco
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$109
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Mon 10/12
8:00 am-12:30 pm
1 stop4h 30m
San Francisco
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$112
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Thu 2/11
8:00 am-12:20 pm
2 stops5h 20m
San Francisco
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$117
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Sat 11/21
10:45 pm-11:55 pm
Nonstop2h 10m
San Francisco
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$119
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Fri 11/27
7:00 am-10:05 am
1 stop4h 05m
San Francisco
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Wed 10/28
8:20 am-10:30 am
Nonstop2h 10m
San Francisco
Wed 11/4
5:05 am-8:00 am
Nonstop1h 55m
$127
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Wed 10/21
7:00 am-9:08 am
Nonstop2h 08m
San Francisco
Sat 10/24
12:25 pm-2:35 pm
Nonstop2h 10m
$137
PhoenixSan Francisco
PHX Phoenix Sky Harbor Intl - SFO San Francisco
PHXSFO
Phoenix Sky Harbor Intl
Tue 10/13
11:05 am-6:10 pm
2 stops7h 05m
San Francisco
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$145
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Mesa to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mesa with our price prediction graph.
PHX-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to San Francisco
MS9-SFO
PHX-SFO
What is the cheapest time of day to fly from MS9 to SFO?
Find hourly flight availability from Mesa to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 19, 2026.
When flying from Mesa to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 60% versus a flight in the evening.
Weekly flight availability from Mesa to San Francisco
Explore weekly flight availability from Mesa to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 19, 2026.
The most flights from MS9 to SFO are scheduled on a Thursday (44 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (12 on average).
How much does it cost to fly round-trip from Mesa to San Francisco?
Airfare is below average for this route at the moment.
Mesa to San Francisco flights typically cost between $162 and $308 in October.The cheapest round-trip price found within the last 5 days was $111 on Frontier (Oct 28-Nov 1).
What is the cheapest day to fly from Mesa to San Francisco?
Use this chart to determine the cheapest time to fly round-trip from Mesa to San Francisco. Price data was last updated on September 12, 2026.
Travelers seeking maximum savings on their Mesa to San Francisco flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 19, 2026.
Read through reviews of airlines operating flights from Mesa to San Francisco, such as Southwest,Alaska Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Mesa to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Emeryville
San Bruno
Burlingame
Rancho Cordova
Roseville
Fairfield
Hayward
Cupertino
Newark
San Ramon
Redwood City
Manteca
Vallejo
San Carlos
Turlock
Davis
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
San Francisco flight routes
Top destinations
Alternative routes for Mesa to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to San Francisco by cabin class
Find flights from Mesa to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mesa and San Francisco flights
Browse other Mesa and San Francisco flight options. Last updated on September 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 19, 2026.
Mesa to San Francisco flights
Consider these flights traveling from Mesa to San Francisco.
Top 6 airlines flying from Mesa to San Francisco
Discover the top 6 airlines that operate flights from Mesa to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$58 | Average$170 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$100 | Average$222 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$105 | Average$269 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$114 | Average$296 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$117 | Average$323 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$130 | Average$284 | FlexibilityNo cancel fee | On-time71% |