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$59+ Cheap flights from Mesa, AZ to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SFO
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to San Francisco are usually found in October or September, booked 43 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Mesa to San Francisco

Keep the following information in mind while searching for Mesa to San Francisco flight deals. Data was last updated September 17, 2025.

Round-trip from

$97
(Kiwi.com)

One-way from

$59
(United Airlines)

Popular in

June

Cheapest in

October

Average price

$157
From Mesa to San Francisco
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One-way flight from Mesa to San Francisco
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Highest demand for flights based on searches. 3% potential increase in price ($7 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($2 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mesa to San Francisco

Cheapest flights from Mesa to San Francisco
Explore the most affordable flight options available from Mesa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/303:31 pmPHX - SFO
Nonstop2h 12mFrontier
Sat 11/19:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 9/16$97
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/283:31 pmPHX - SFO
Nonstop2h 12mFrontier
Thu 10/309:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 9/17$98
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/73:31 pmPHX - SFO
Nonstop2h 12mFrontier
Mon 11/108:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 9/15$101
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/293:31 pmPHX - SFO
Nonstop2h 12mFrontier
Thu 10/309:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 9/16$102
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/283:31 pmPHX - SFO
Nonstop2h 12mMultiple Airlines
Wed 10/297:00 amSFO - PHX
1 stop3h 58mMultiple Airlines
Deal found 9/15$104
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:31 pmPHX - SFO
Nonstop2h 12mFrontier
Mon 11/108:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 9/16$105
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:15 pmPHX - SFO
1 stop6h 40mMultiple Airlines
Sun 11/98:55 pmSFO - PHX
Nonstop2h 04mMultiple Airlines
Deal found 9/15$106
This Trip.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amPHX - SFO
1 stop5h 06mMultiple Airlines
Sun 10/2610:25 pmSFO - PHX
Nonstop2h 07mMultiple Airlines
Deal found 9/14$107
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/238:30 amPHX - SFO
1 stop8h 50mFrontier
Sun 10/2610:25 pmSFO - PHX
Nonstop2h 07mFrontier
Deal found 9/14$112
This Flightnetwork deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/98:30 amPHX - SFO
1 stop8h 50mFrontier
Mon 10/139:23 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 9/15$113
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/64:10 pmPHX - SFO
Nonstop2h 09mFrontier
Thu 10/910:25 pmSFO - PHX
Nonstop2h 07mFrontier
Deal found 9/16$114
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:16 pmPHX - SFO
1 stop9h 11mFrontier
Tue 11/48:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 9/16$115

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Mesa to San Francisco that are best for you.

Fly from

Mesa

Fly to

San Francisco

Route

Depart

Return

Price

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sat 2/28

4:47 pm-5:51 pm

Nonstop2h 04m

San Francisco

Tue 3/3

12:49 pm-3:47 pm

Nonstop1h 58m

$117

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Tue 10/28

8:40 am-10:45 am

Nonstop2h 05m

San Francisco

Wed 11/26

5:00 am-12:00 pm

1 stop6h 00m

$127

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Tue 10/14

8:40 am-10:45 am

Nonstop2h 05m

San Francisco

Tue 10/21

10:25 am-4:50 pm

1 stop6h 25m

$127

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Tue 10/7

8:45 pm-10:45 pm

Nonstop2h 00m

San Francisco

Thu 10/9

6:20 am-8:15 am

Nonstop1h 55m

$129

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Tue 10/14

10:04 am-12:15 pm

Nonstop2h 11m

San Francisco

Sun 10/19

7:00 am-8:59 am

Nonstop1h 59m

$132

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Wed 10/15

7:10 am-9:16 am

Nonstop2h 06m

San Francisco

Sun 10/19

7:00 am-8:59 am

Nonstop1h 59m

$132

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sat 10/11

2:45 pm-4:45 pm

Nonstop2h 00m

San Francisco

Mon 10/13

6:20 am-8:15 am

Nonstop1h 55m

$137

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Thu 10/23

5:50 pm-7:45 pm

Nonstop1h 55m

San Francisco

Sun 10/26

10:35 am-12:30 pm

Nonstop1h 55m

$147

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Thu 11/6

9:45 pm-10:55 pm

Nonstop2h 10m

San Francisco

Mon 11/10

5:15 am-8:05 am

Nonstop1h 50m

$147

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Tue 10/7

3:45 pm-5:49 pm

Nonstop2h 04m

San Francisco

Wed 10/8

7:00 am-8:59 am

Nonstop1h 59m

$153

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 22 results
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Best time to book a flight from Mesa to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to San Francisco

How far ahead should I book a flight from Mesa to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to San Francisco. Price data was last updated on September 12, 2025.

Booking 43 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Mesa to San Francisco (average of $276). Flying from Mesa to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SFO?

Find hourly flight availability from Mesa to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Mesa to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Mesa to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Mesa to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to San Francisco flight should consider departing on Saturday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mesa to San Francisco

Explore weekly flight availability from Mesa to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2025.

The most flights from MS9 to SFO are scheduled on a Thursday (40 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (26 on average).

How much does it cost to fly round-trip from Mesa to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Mesa to San Francisco, such as Alaska Airlines, Southwest, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

7.8

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

7.8

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Southwest
8.0
Very good
4,242 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

7.8

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,926 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

7.8

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

7.8

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,173 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

7.8

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Mesa to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Mesa?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Mesa to San Francisco. 6 airlines have flights to San Francisco from Mesa on a regular basis. Booking flights from Mesa to San Francisco should not be difficult; the airport handles an average of 33 inbound flights from Mesa per day.

  • How long is the flight from Mesa to San Francisco?

    A quick flight from Mesa to San Francisco can take about 2h 04m. Hawaiian Airlines provides one of the quickest options available for as low as $117. The distance between Mesa and San Francisco is about 650 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines to fly from Mesa to San Francisco one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $59. However, be on the lookout for offers from Alaska Airlines and United Airlines, as they are both options that can get you from Mesa to San Francisco for a low price.

  • What are the most reliable airlines from Mesa to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Mesa to San Francisco consider choosing ITA Airways (100%), Air China (94%) or ANA (90%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Mesa to San Francisco?

    On average you can expect to pay $1,106 for a flight from Mesa to San Francisco. The cheapest flight overall is $63 while the most popular route, (Phoenix Sky Harbor Intl - San Francisco) is currently priced at $38.

  • Can I find deals for flights from Mesa to San Francisco that include hotel bookings?

    Yes. In addition to deals on Mesa to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to San Francisco.

  • Can I find deals for business class flights from Mesa to San Francisco?

    Yes. Cheapflights offers flight deals from Mesa to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Mesa to San Francisco (average of $276). Flying from Mesa to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Santa Clara
Manteca
Sunnyvale
Hollister
Vacaville
Foster City
Union City
Vallejo
Burlingame
Redwood City
San Mateo
San Leandro
Lathrop

Browse thousands of different options on Cheapflights for your next trip

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Top 6 airlines flying from Mesa to San Francisco

Discover the top 6 airlines that operate flights from Mesa to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$53Average$125FlexibilityNo cancel feeOn-time62%
Hawaiian AirlinesCheapest$68Average$169FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$114Average$191FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$125Average$263FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$125Average$206FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$133Average$207FlexibilityNo cancel feeOn-time71%

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