HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Francisco

$51+ Cheap flights from Mesa, AZ to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SFO
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mesa to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Mesa to San Francisco are usually found in October or August, booked 70 days in advance, depart on a Friday or Thursday and return on a Friday

Find flight deals from Mesa to San Francisco

Cheapest flights from Mesa to San Francisco
Explore the most affordable flight options available from Mesa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This Priceline deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:31 pmPHX - SFO
Nonstop2h 12mFrontier
Sat 11/88:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 10/21$86
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/73:31 pmPHX - SFO
Nonstop2h 12mFrontier
Sun 11/91:45 pmSFO - PHX
1 stop17h 35mFrontier
Deal found 10/21$87
This Alaska Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:02 amPHX - SFO
1 stop4h 08mAlaska Airlines
Thu 12/411:35 amSFO - PHX
Nonstop2h 06mAlaska Airlines
Deal found 10/23$88
This Priceline deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:31 pmPHX - SFO
Nonstop2h 12mFrontier
Sat 11/88:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 10/23$89
This Alaska Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:23 pmPHX - SFO
Nonstop2h 16mAlaska Airlines
Sun 12/147:00 amSFO - PHX
1 stop15h 59mAlaska Airlines
Deal found 10/22$90
This Frontier deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:31 pmPHX - SFO
Nonstop2h 12mFrontier
Mon 11/38:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 10/21$91
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:08 pmPHX - SFO
Nonstop2h 06mAmerican Airlines
Sat 12/138:20 amSFO - PHX
Nonstop1h 59mAmerican Airlines
Deal found 10/22$92
This Frontier deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/293:31 pmPHX - SFO
Nonstop2h 12mFrontier
Fri 10/319:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 10/23$93
This Alaska Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:56 pmPHX - SFO
1 stop4h 52mAlaska Airlines
Sat 12/611:35 amSFO - PHX
Nonstop2h 06mAlaska Airlines
Deal found 10/21$94
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/88:00 pmPHX - SFO
1 stop4h 47mFrontier
Sat 11/158:55 pmSFO - PHX
Nonstop2h 04mFrontier
Deal found 10/21$95
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/43:31 pmPHX - SFO
Nonstop2h 12mMultiple Airlines
Tue 11/114:16 pmSFO - PHX
Nonstop2h 01mMultiple Airlines
Deal found 10/21$96
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:30 amPHX - SFO
1 stop10h 00mFrontier
Tue 12/308:16 pmSFO - PHX
Nonstop2h 07mFrontier
Deal found 10/21$97

Cheap flight deals from Mesa to San Francisco

Keep the following information in mind while searching for Mesa to San Francisco flight deals. Data was last updated October 23, 2025.

Round-trip from

$85
(Expedia)

One-way from

$51
(Southwest)

Popular in

June

Cheapest in

October

Average price

$161
From Mesa to San Francisco
Search Deals
One-way flight from Mesa to San Francisco
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($6 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Mesa to San Francisco that are best for you.

Fly from

Mesa

Fly to

San Francisco

Route

Depart

Return

Price

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Wed 12/3

7:56 pm-10:48 pm

1 stop3h 52m

San Francisco

Sun 12/7

11:35 am-2:41 pm

Nonstop2h 06m

$88

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sat 12/6

5:10 am-9:30 am

1 stop5h 20m

San Francisco

Mon 12/8

5:05 am-7:55 am

Nonstop1h 50m

$90

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Thu 1/8

6:05 am-7:21 am

Nonstop2h 16m

San Francisco

Thu 1/15

8:55 pm-11:57 pm

Nonstop2h 02m

$91

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Wed 1/21

8:55 am-12:05 pm

1 stop4h 10m

San Francisco

Wed 1/28

9:55 am-2:20 pm

1 stop3h 25m

$98

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Fri 12/12

3:23 pm-4:39 pm

Nonstop2h 16m

San Francisco

Mon 12/15

11:25 am-11:59 pm

1 stop11h 34m

$102

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Thu 12/4

10:10 am-11:30 am

Nonstop2h 20m

San Francisco

Thu 12/4

3:05 pm-10:05 pm

1 stop6h 00m

$104

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sat 12/6

3:23 pm-4:39 pm

Nonstop2h 16m

San Francisco

Sat 12/13

6:13 pm-11:59 pm

1 stop4h 46m

$108

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Tue 12/2

3:45 pm-8:10 pm

2 stops5h 25m

San Francisco

Mon 12/8

5:05 am-7:55 am

Nonstop1h 50m

$112

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Thu 1/8

11:41 am-4:32 pm

1 stop5h 51m

San Francisco

Mon 1/12

7:00 am-3:03 pm

1 stop7h 03m

$114

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Mon 1/5

8:36 pm-4:02 pm

1 stop20h 26m

San Francisco

Fri 1/9

10:10 am-1:09 pm

Nonstop1h 59m

$116

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/22

Showing 1-10 of 24 results
1
2
3

Best time to book a flight from Mesa to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to San Francisco

How far ahead should I book a flight from Mesa to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to San Francisco. Price data was last updated on October 17, 2025.

Booking 70 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Mesa to San Francisco (average of $38). Flying from Mesa to San Francisco in July is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SFO?

Find hourly flight availability from Mesa to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2025.

When flying from Mesa to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 72% versus a flight in the evening.

What is the cheapest day to fly from Mesa to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Mesa to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to San Francisco flight should consider departing on Wednesday mornings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mesa to San Francisco

Explore weekly flight availability from Mesa to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 23, 2025.

The most flights from MS9 to SFO are scheduled on a Thursday (39 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 23, 2025.
Read through reviews of airlines operating flights from Mesa to San Francisco, such as Alaska Airlines, Southwest, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,155 reviews

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Crew

8.5

Food

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,155 reviews
Alaska Airlines
8.0
Very good
11,155 reviews

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Crew

8.5

Food

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Southwest
8.0
Very good
4,237 reviews
Alaska Airlines
8.0
Very good
11,155 reviews

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Crew

8.5

Food

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,991 reviews
Alaska Airlines
8.0
Very good
11,155 reviews

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Crew

8.5

Food

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,028 reviews
Alaska Airlines
8.0
Very good
11,155 reviews

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Crew

8.5

Food

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,128 reviews
Alaska Airlines
8.0
Very good
11,155 reviews

Comfort

7.8

Entertainment

7.0

Boarding

8.1

Crew

8.5

Food

7.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Mesa to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Mesa?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Mesa to San Francisco. 6 airlines have flights to San Francisco from Mesa on a regular basis. Booking flights from Mesa to San Francisco should not be difficult; the airport handles an average of 21 inbound flights from Mesa per day.

  • How long is the flight from Mesa to San Francisco?

    A quick flight from Mesa to San Francisco can take about 2h 16m. Alaska Airlines provides one of the quickest options available for as low as $91. The distance between Mesa and San Francisco is about 650 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mesa to San Francisco one-way?

    The cheapest airline one-way is Alaska Airlines, with whom users have recently found tickets for as low as $51. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from Mesa to San Francisco for a low price.

  • What are the most reliable airlines from Mesa to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Mesa to San Francisco consider choosing Air China (94%), ANA (92%) or United Airlines (86%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Mesa to San Francisco?

    On average you can expect to pay $840 for a flight from Mesa to San Francisco. The cheapest flight overall is $46 while the most popular route, (Phoenix Sky Harbor Intl - San Francisco) is currently priced at $54.

  • Can I find deals for flights from Mesa to San Francisco that include hotel bookings?

    Yes. In addition to deals on Mesa to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to San Francisco.

  • Can I find deals for business class flights from Mesa to San Francisco?

    Yes. Cheapflights offers flight deals from Mesa to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Mesa to San Francisco (average of $38). Flying from Mesa to San Francisco in July is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Santa Clara
Manteca
Sunnyvale
Vacaville
Vallejo
Hollister
Foster City
Union City
Fairfield
Burlingame
Redwood City
Lodi
San Mateo

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mesa to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
Sky Harbor Intl to Las Vegas flights
Sky Harbor Intl to Los Angeles flights
Sky Harbor Intl to San Francisco flights
Las Vegas to Los Angeles flights
Las Vegas to Burbank flights
Sky Harbor Intl to Santa Ana flights
Tucson to Las Vegas flights
Las Vegas to San Francisco flights
Sky Harbor Intl to San Diego flights
Las Vegas to Santa Ana flights
Las Vegas to Ontario flights
Sky Harbor Intl to Sacramento flights
Sky Harbor Intl to San Jose flights
Tucson to Los Angeles flights
Sky Harbor Intl to Ontario flights
Phoenix-Mesa Gateway to Las Vegas flights
Las Vegas to Reno flights
Las Vegas to San Diego flights
Las Vegas to San Jose flights
Sky Harbor Intl to Burbank flights
Las Vegas to Oakland flights
Las Vegas to Sacramento flights
Tucson to San Francisco flights
Sky Harbor Intl to Reno flights
Tucson to San Diego flights
Tucson to Ontario flights
Sky Harbor Intl to Oakland flights
Las Vegas to Long Beach flights
Sky Harbor Intl to Fresno flights
Tucson to Santa Ana flights
Sky Harbor Intl to Santa Barbara flights
Sky Harbor Intl to San Luis Obispo flights
Sky Harbor Intl to Monterey flights
Sky Harbor Intl to Medford flights
Tucson to Sacramento flights
Sky Harbor Intl to Santa Rosa flights
Las Vegas to Santa Rosa flights
Las Vegas to Stockton flights
Las Vegas to Palm Springs flights
Las Vegas to San Luis Obispo flights
Tucson to Reno flights
Tucson to San Jose flights
Tucson to Oakland flights
Tucson to Burbank flights
Las Vegas to Santa Barbara flights
Sky Harbor Intl to Long Beach flights
Las Vegas to Fresno flights
Sky Harbor Intl to Palm Springs flights
Prescott to Los Angeles flights
Las Vegas to Monterey flights

Top 6 airlines flying from Mesa to San Francisco

Discover the top 6 airlines that operate flights from Mesa to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$53Average$147FlexibilityNo cancel feeOn-time62%
Hawaiian AirlinesCheapest$68Average$169FlexibilityNo cancel feeOn-time85%
SouthwestCheapest$108Average$193FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$114Average$189FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$119Average$274FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$130Average$205FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.