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$53+ Cheap flights from Mesa, AZ to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SFO
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to San Francisco are usually found in January or October, booked 70 days in advance, depart on a Friday or Thursday and return on a Saturday

Cheap flight deals from Mesa to San Francisco

Cheapest flights from Mesa to San Francisco
Explore the most affordable flight options available from Mesa to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Super.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:30 amPHX - SFO
Nonstop2h 16mFrontier
Tue 12/308:12 pmSFO - PHX
Nonstop2h 07mFrontier
Deal found 12/15$109
This Orbitz deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:58 amPHX - SFO
1 stop12h 38mFrontier
Tue 12/308:12 pmSFO - PHX
Nonstop2h 07mFrontier
Deal found 12/15$121
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:30 amPHX - SFO
Nonstop2h 16mFrontier
Thu 1/88:14 pmSFO - PHX
Nonstop2h 07mFrontier
Deal found 12/17$122
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:30 amPHX - SFO
Nonstop2h 16mFrontier
Sat 1/310:41 amSFO - PHX
Nonstop2h 02mFrontier
Deal found 12/16$128
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:30 amPHX - SFO
Nonstop2h 16mFrontier
Sun 1/49:56 pmSFO - PHX
Nonstop2h 02mFrontier
Deal found 12/16$129
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:43 pmPHX - SFO
1 stop17h 40mFrontier
Sat 1/310:41 amSFO - PHX
Nonstop2h 02mFrontier
Deal found 12/16$133
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:43 pmPHX - SFO
1 stop17h 40mFrontier
Sun 1/49:56 pmSFO - PHX
Nonstop2h 02mFrontier
Deal found 12/16$134
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:11 pmPHX - SFO
Nonstop2h 14mUnited Airlines
Wed 12/314:35 pmSFO - PHX
Nonstop2h 02mUnited Airlines
Deal found 12/15$137
This Priceline deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:30 amPHX - SFO
Nonstop2h 16mFrontier
Wed 12/311:29 pmSFO - PHX
1 stop4h 38mFrontier
Deal found 12/15$152
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:30 amPHX - SFO
1 stop10h 00mFrontier
Sat 1/310:41 amSFO - PHX
Nonstop2h 02mFrontier
Deal found 12/16$153
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:30 amPHX - SFO
1 stop10h 00mFrontier
Sun 1/49:56 pmSFO - PHX
Nonstop2h 02mFrontier
Deal found 12/16$154

Find flight deals from Mesa to San Francisco

Keep the following information in mind while searching for Mesa to San Francisco flight deals. Data was last updated December 18, 2025.

Round-trip from

$80
(Flightnetwork)

One-way from

$53
(Super.com)

Popular in

November

Cheapest in

January

Average price

$189
From Mesa to San Francisco
Search Deals
One-way flight from Mesa to San Francisco
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Mesa to San Francisco that are best for you.

Fly from

Mesa

Fly to

San Francisco

Route

Depart

Return

Price

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sat 2/14

7:06 pm-12:28 am

1 stop6h 22m

San Francisco

Thu 3/12

8:25 pm-10:28 pm

Nonstop2h 03m

$110

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Tue 1/20

4:36 pm-5:50 pm

Nonstop2h 14m

San Francisco

Sun 1/25

5:05 pm-8:07 pm

Nonstop2h 02m

$124

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sat 2/7

4:36 pm-5:50 pm

Nonstop2h 14m

San Francisco

Sat 2/7

8:55 pm-11:57 pm

Nonstop2h 02m

$126

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Tue 2/10

3:05 pm-6:20 pm

1 stop4h 15m

San Francisco

Sun 3/15

10:35 pm-12:43 am

Nonstop2h 08m

$127

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Thu 2/12

7:36 pm-12:28 am

1 stop5h 52m

San Francisco

Sun 3/15

10:35 pm-12:43 am

Nonstop2h 08m

$127

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sun 2/1

6:05 am-7:21 am

Nonstop2h 16m

San Francisco

Tue 2/3

8:55 pm-11:57 pm

Nonstop2h 02m

$131

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Fri 1/16

6:05 am-7:21 am

Nonstop2h 16m

San Francisco

Mon 1/19

5:05 pm-8:07 pm

Nonstop2h 02m

$131

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sat 2/14

4:40 pm-5:58 pm

Nonstop2h 18m

San Francisco

Tue 3/17

11:30 am-1:35 pm

Nonstop2h 05m

$133

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sat 1/17

1:30 pm-8:35 pm

1 stop8h 05m

San Francisco

Mon 1/19

5:30 am-8:20 am

Nonstop1h 50m

$134

PhoenixSan Francisco

PHX - SFO

PHXSFO

Phoenix Sky Harbor Intl

Sun 2/1

8:55 pm-10:05 pm

Nonstop2h 10m

San Francisco

Tue 2/3

9:55 am-2:20 pm

1 stop3h 25m

$147

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 24 results
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Best time to book a flight from Mesa to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to San Francisco

How far ahead should I book a flight from Mesa to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to San Francisco. Price data was last updated on December 12, 2025.

Booking 70 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Mesa to San Francisco (average of $39). Flying from Mesa to San Francisco in July is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SFO?

Find hourly flight availability from Mesa to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

When flying from Mesa to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 69% versus a flight in the evening.

What is the cheapest day to fly from Mesa to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Mesa to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to San Francisco flight should consider departing on Wednesday mornings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Mesa to San Francisco, such as Alaska Airlines, Southwest, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,475 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,475 reviews
Alaska Airlines
8.0
Very good
11,475 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Southwest
7.9
Good
4,249 reviews
Alaska Airlines
8.0
Very good
11,475 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
9,091 reviews
Alaska Airlines
8.0
Very good
11,475 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,054 reviews
Alaska Airlines
8.0
Very good
11,475 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,082 reviews
Alaska Airlines
8.0
Very good
11,475 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Mesa to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Mesa?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Mesa to San Francisco. 6 airlines have flights to San Francisco from Mesa on a regular basis. Booking flights from Mesa to San Francisco should not be difficult; the airport handles an average of 15 inbound flights from Mesa per day.

  • How long is the flight from Mesa to San Francisco?

    A quick flight from Mesa to San Francisco can take about 2h 14m. Frontier provides one of the quickest options available for as low as $124. The distance between Mesa and San Francisco is about 650 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mesa to San Francisco one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $30. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from Mesa to San Francisco for a low price.

  • What are the most reliable airlines from Mesa to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Mesa to San Francisco consider choosing Air China (94%), ANA (87%) or Air Canada (86%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Mesa to San Francisco?

    On average you can expect to pay $836 for a flight from Mesa to San Francisco. The cheapest flight overall is $51 while the most popular route, (Phoenix Sky Harbor Intl - San Francisco) is currently priced at $59.

  • Can I find deals for flights from Mesa to San Francisco that include hotel bookings?

    Yes. In addition to deals on Mesa to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to San Francisco.

  • Can I find deals for business class flights from Mesa to San Francisco?

    Yes. Cheapflights offers flight deals from Mesa to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Mesa to San Francisco (average of $39). Flying from Mesa to San Francisco in July is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Redwood City
Sunnyvale
Santa Clara
San Bruno
Daly City
San Carlos
Vallejo
Hollister
San Ramon
Foster City
Union City
Davis
Emeryville

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mesa to San Francisco

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Top 6 airlines flying from Mesa to San Francisco

Discover the top 6 airlines that operate flights from Mesa to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$53Average$128FlexibilityNo cancel feeOn-time62%
Hawaiian AirlinesCheapest$68Average$169FlexibilityNo cancel feeOn-time85%
SouthwestCheapest$105Average$194FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$110Average$186FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$110Average$241FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$127Average$202FlexibilityNo cancel feeOn-time71%

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