Saturday is generally a great day to depart. Flying on this day could help you save up to 358%.
Find a great deal and save up to 99% by booking at least 61 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Mesa to San Francisco within the next two weeks, with the cheapest ticket starting at $416.
A simple way to save on the total cost of your ticket is to fly from Mesa to San Francisco at noon. If you’re flexible enough to do this you can expect to save up to 65% on your trip compared to booking a flight in the morning.