San Francisco

$111+ Cheap flights from Medford to San Francisco (MFR - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SFO
Apr 13 — Apr 201
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Find cheap flights from Medford to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Medford to San Francisco are usually found in November or February, booked 72 days in advance, depart on a Friday or Wednesday and return on a Saturday

Cheap flight deals from Medford to San Francisco

Cheapest flights from Medford to San Francisco
Explore the most affordable flight options available from Medford to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:10 am
MFR
-
SFO
1 stop7h 55m
Delta
Mon 4/204:40 pm
SFO
-
MFR
1 stop6h 40m
Delta
Deal found 3/10$205
This Alaska Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:38 pm
MFR
-
SFO
1 stop4h 13m
Alaska Airlines
Tue 5/57:40 pm
SFO
-
MFR
2 stops21h 19m
Alaska Airlines
Deal found 3/11$223
This Trip.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:24 pm
MFR
-
SFO
1 stop4h 56m
Alaska Airlines
Tue 5/52:00 pm
SFO
-
MFR
1 stop5h 04m
Alaska Airlines
Deal found 3/13$225
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:12 pm
MFR
-
SFO
Nonstop1h 23m
United Airlines
Sat 4/2510:20 am
SFO
-
MFR
Nonstop1h 28m
United Airlines
Deal found 3/12$229
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:34 pm
MFR
-
SFO
Nonstop1h 36m
United Airlines
Sat 4/184:13 pm
SFO
-
MFR
Nonstop1h 40m
United Airlines
Deal found 3/12$237
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:30 pm
MFR
-
SFO
1 stop6h 27m
Delta
Wed 4/151:10 pm
SFO
-
MFR
2 stops10h 10m
Delta
Deal found 3/11$239
This Alaska Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:24 pm
MFR
-
SFO
1 stop4h 56m
Alaska Airlines
Sat 4/257:40 am
SFO
-
MFR
1 stop4h 21m
Alaska Airlines
Deal found 3/13$240
This Alaska Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:24 pm
MFR
-
SFO
1 stop4h 56m
Alaska Airlines
Thu 4/2310:25 am
SFO
-
MFR
1 stop6h 34m
Alaska Airlines
Deal found 3/11$242

Find flight deals from Medford to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$205
(Delta)

One-way from

$103
(Delta)

Popular in

March

Cheapest in

November

Average price

$409

Good round-trip deal

$341 or less

Good one-way deal

$214 or less
Provider with most accurate pricing for Medford-San Francisco flight deals.
Provider most trusted by Cheapflights users for Medford-San Francisco flights.
From Medford to San Francisco
One-way flight from Medford to San Francisco
Highest demand for flights based on searches. 13% potential increase in price ($43 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in March 2026
Price to beat on a round-trip flight from Medford to San Francisco.
Price to beat on a one-way flight from Medford to San Francisco.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Medford to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Fri 4/17

5:28 pm-11:37 pm

1 stop6h 09m

San Francisco

Mon 4/20

4:40 pm-11:20 pm

1 stop6h 40m

$205

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Wed 4/22

6:10 am-3:21 pm

2 stops9h 11m

San Francisco

Wed 4/29

4:40 pm-11:20 pm

1 stop6h 40m

$210

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Sat 5/2

12:38 pm-4:51 pm

1 stop4h 13m

San Francisco

Tue 5/5

7:40 pm-4:59 pm

2 stops21h 19m

$223

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Wed 4/22

4:24 pm-9:20 pm

1 stop4h 56m

San Francisco

Thu 4/23

9:00 am-4:59 pm

1 stop7h 59m

$240
Quickest round-trip

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Wed 8/26

6:26 pm-8:08 pm

Nonstop1h 42m

San Francisco

Sun 8/30

9:00 pm-10:41 pm

Nonstop1h 41m

$249

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Wed 8/26

3:21 pm-7:49 pm

1 stop4h 28m

San Francisco

Sun 8/30

2:00 pm-11:55 pm

1 stop9h 55m

$249

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Sun 4/5

11:13 am-6:44 pm

1 stop7h 31m

San Francisco

Sun 4/12

10:31 am-4:36 pm

1 stop6h 05m

$254

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Tue 4/28

11:14 am-11:59 pm

2 stops12h 45m

San Francisco

Tue 5/5

1:10 pm-11:20 pm

2 stops10h 10m

$255
Cheapest one-way

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Fri 4/10

5:30 pm-11:57 pm

1 stop6h 27m

$123

MedfordSan Francisco

MFR - SFO

MFRSFO

Medford

Sat 4/11

11:13 am-6:44 pm

1 stop7h 31m

$123

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Medford to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to San Francisco in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to San Francisco

How far ahead should I book a flight from Medford to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Medford to San Francisco. Price data was last updated on March 13, 2026.

The best time to book flights from Medford to San Francisco is 21 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Medford to San Francisco?

Currently, April is the cheapest month in which you can book a flight from Medford to San Francisco (average of $186). Flying from Medford to San Francisco in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SFO?

Find hourly flight availability from Medford to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 14, 2026.

When flying from Medford to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 14, 2026.
Get a feel of what it's like to fly with Alaska Airlines,Hawaiian Airlines, andUnited Airlines from Medford to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Crew

8.5

Overall

8.0

Entertainment

7.0

Comfort

7.8

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2025

PDX - SJC

They had no snacks and had to pay for the Wifi.

Boarding

8.1

Crew

8.5

Overall

8.0

Entertainment

7.0

Comfort

7.8

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2025

PDX - SJC

They had no snacks and had to pay for the Wifi.

Boarding

8.1

Crew

8.5

Overall

8.0

Entertainment

7.0

Comfort

7.8

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2025

PDX - SJC

They had no snacks and had to pay for the Wifi.

Boarding

8.1

Crew

8.5

Overall

8.0

Entertainment

7.0

Comfort

7.8

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2025

PDX - SJC

They had no snacks and had to pay for the Wifi.

Related info for your journey

Find useful and relevant information for your journey from Medford to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from Medford to San Francisco?

    If you wish to fly to San Francisco from Medford, then you need to book flights from Medford to San Francisco. There are 7 flights from Medford (MFR) to San Francisco (SFO) per day to choose from. Flights to San Francisco from Medford are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 1h 23m is how long a nonstop flight from Medford to San Francisco typically takes.

  • How popular is this Medford to San Francisco flight route?

  • How long is the flight from Medford to San Francisco?

    Delta and Alaska Airlines can get you from Medford to San Francisco in just under 4h 13m. Your travel time can differ by up to 1h 56m. There are 329 mi between Medford and San Francisco. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Medford to San Francisco round-trip?

    Currently priced at $189, United Airlines will fly you from Medford to San Francisco and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Alaska Airlines and Hawaiian Airlines - these airlines can fly you to your destination from $192 and $198, respectively. You may be able to fly from Medford to San Francisco for 29% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Medford to San Francisco?

    Consider Copa Airlines (81%), Avianca (75%) or Air New Zealand (71%) when booking your flight. These represent the most reliable airlines when flying from Medford to San Francisco.

  • What are the cheapest flights from Medford to San Francisco?

    Looking at all options, your cheapest flight can be booked for $131. While the most popular route (Medford - San Francisco) can be booked for $205 on average, our data indicates $632 when flying from Medford to San Francisco.

  • Can I find deals for flights from Medford to San Francisco that include hotel bookings?

    Yes. In addition to deals on Medford to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to San Francisco.

  • Can I find deals for business class flights from Medford to San Francisco?

    Yes. Cheapflights offers flight deals from Medford to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to San Francisco?

    Currently, April is the cheapest month in which you can book a flight from Medford to San Francisco (average of $186). Flying from Medford to San Francisco in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
Rancho Cordova
San Bruno
San Ramon
Sunnyvale
Vacaville
San Carlos
Redwood City
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Rohnert Park

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Medford to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Medford to San Francisco

Discover the top 3 airlines that operate flights from Medford to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$189Average$255FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$192Average$263FlexibilityNo cancel feeOn-time75%
Hawaiian AirlinesCheapest$198Average$218FlexibilityNo cancel feeOn-time85%

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