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$119+ Cheap flights from Key Largo, FL to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — SFO
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to San Francisco are usually found in January or November, booked 56 days in advance, depart on a Tuesday or Thursday and return on a Wednesday

Cheap flight deals from Key Largo to San Francisco

Keep the following information in mind while searching for Key Largo to San Francisco flight deals. Data was last updated August 14, 2025.

Round-trip from

$229
(American Airlines)

One-way from

$119
(Southwest)

Popular in

June

Cheapest in

January

Average price

$319
From Key Largo to San Francisco
Search Deals
One-way flight from Key Largo to San Francisco
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Highest demand for flights based on searches. 5% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Key Largo to San Francisco

Cheapest flights from Key Largo to San Francisco
Explore the most affordable flight options available from Key Largo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Frontier deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/158:00 amMIA - SFO
2 stops13h 19mFrontier
Thu 9/2510:37 pmSFO - MIA
2 stops16h 57mFrontier
Deal found 8/14$231
This Frontier deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/198:00 amMIA - SFO
2 stops13h 19mFrontier
Mon 9/296:29 amSFO - MIA
2 stops15h 13mFrontier
Deal found 8/14$232
This Frontier deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:00 amMIA - SFO
2 stops20h 02mFrontier
Thu 9/185:45 amSFO - MIA
2 stops14h 15mFrontier
Deal found 8/13$234
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3011:40 amMIA - SFO
1 stop9h 40mSouthwest
Sat 9/69:55 amSFO - MIA
1 stop8h 45mSouthwest
Deal found 8/14$235
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1312:18 pmMIA - SFO
1 stop12h 03mFrontier
Wed 9/177:10 amSFO - MIA
1 stop14h 34mFrontier
Deal found 8/13$236
This Frontier deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:15 amMIA - SFO
2 stops16h 55mFrontier
Mon 10/206:34 amSFO - MIA
2 stops15h 00mFrontier
Deal found 8/14$237
This Frontier deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/69:28 amMIA - SFO
2 stops11h 51mFrontier
Sun 10/1210:23 pmSFO - MIA
1 stop9h 11mFrontier
Deal found 8/14$238
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:45 amMIA - SFO
1 stop18h 45mFrontier
Sat 9/2010:49 amSFO - MIA
1 stop10h 55mFrontier
Deal found 8/13$239
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:59 pmMIA - SFO
2 stops18h 44mMultiple Airlines
Thu 9/255:45 amSFO - MIA
1 stop10h 10mMultiple Airlines
Deal found 8/13$240
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:35 pmMIA - SFO
Nonstop6h 14mUnited Airlines
Wed 9/175:00 amSFO - MIA
1 stop7h 46mUnited Airlines
Deal found 8/13$241
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:59 pmMIA - SFO
2 stops18h 44mMultiple Airlines
Sat 9/2710:49 amSFO - MIA
1 stop10h 55mMultiple Airlines
Deal found 8/13$242
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/236:15 amMIA - SFO
1 stop19h 18mFrontier
Mon 8/2510:29 pmSFO - MIA
1 stop13h 24mFrontier
Deal found 8/13$243

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Key Largo to San Francisco that are best for you.

Fly from

Key Largo

Fly to

San Francisco

Route

Depart

Return

Price

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Mon 9/15

8:00 am-6:19 pm

2 stops13h 19m

San Francisco

Thu 9/18

5:45 am-11:27 pm

2 stops14h 42m

$231

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 9/13

6:35 pm-9:49 pm

Nonstop6h 14m

San Francisco

Sat 9/20

8:55 am-5:33 pm

Nonstop5h 38m

$231

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 9/13

6:35 pm-9:49 pm

Nonstop6h 14m

San Francisco

Wed 9/17

8:55 am-5:33 pm

Nonstop5h 38m

$231

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Mon 9/29

6:00 am-1:17 pm

1 stop10h 17m

San Francisco

Tue 10/7

11:59 pm-8:23 am

Nonstop5h 24m

$231

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 9/11

6:00 am-11:02 pm

2 stops20h 02m

San Francisco

Thu 9/18

5:45 am-11:00 pm

2 stops14h 15m

$234

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 8/30

11:40 am-6:20 pm

1 stop9h 40m

San Francisco

Sat 9/6

9:55 am-9:40 pm

1 stop8h 45m

$235

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 10/22

1:15 pm-9:50 pm

2 stops11h 35m

$119

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 11/12

1:30 pm-10:30 pm

2 stops12h 00m

$119

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 10/15

1:15 pm-9:50 pm

2 stops11h 35m

$119

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Mon 9/15

7:23 pm-9:32 pm

1 stop29h 09m

$121

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 18 results
1
2

Best time to book a flight from Key Largo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to San Francisco

How far ahead should I book a flight from Key Largo to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to San Francisco. Price data was last updated on August 8, 2025.

The price you pay for your flight from Key Largo to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Key Largo to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $276). Flying from Key Largo to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SFO?

Find hourly flight availability from Key Largo to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

When flying from Key Largo to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to San Francisco flight should consider departing on Thursday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to San Francisco

Explore weekly flight availability from Key Largo to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 14, 2025.

The most flights from KE9 to SFO are scheduled on a Thursday (27 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (19 on average).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 14, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Key Largo to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
JetBlue
7.2
Good
2,913 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
5.8
Fair
3,217 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Key Largo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Key Largo?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Key Largo to San Francisco. 7 airlines have flights to San Francisco from Key Largo on a regular basis. Booking flights from Key Largo to San Francisco should not be difficult; the airport handles an average of 23 inbound flights from Key Largo per day.

  • How popular is this Key Largo to San Francisco flight route?

    The Key Largo to San Francisco flight path was viewed by 63 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the most reliable airlines from Key Largo to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Key Largo to San Francisco consider choosing Royal Air Maroc (100%), Japan Airlines (93%) or GOL (79%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Key Largo to San Francisco?

    Looking for the cheapest flight from Key Largo to San Francisco? While on average our users pay $1,334, our data indicates the cheapest price to be $115. The most popular route (Miami - San Francisco), is priced around $217.

  • Can I find deals for flights from Key Largo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Key Largo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to San Francisco.

  • Can I find deals for business class flights from Key Largo to San Francisco?

    Yes. Cheapflights offers flight deals from Key Largo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $276). Flying from Key Largo to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Mountain View
Turlock
Santa Clara
Hollister
Antioch
Watsonville
Manteca
Sunnyvale
Newark
Milpitas
Campbell
Foster City
San Leandro
Burlingame
Redwood City
Vallejo

Browse thousands of different options on Cheapflights for your next trip

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Top 7 airlines flying from Key Largo to San Francisco

Discover the top 7 airlines that operate flights from Key Largo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$81Average$171FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$99Average$282FlexibilityNo cancel feeOn-time62%
DeltaCheapest$128Average$276FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$176Average$381FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$178Average$342FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$188Average$315FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$250Average$323FlexibilityNo cancel feeOn-time63%

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