$116+ Cheap flights from Key Largo, FL to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — SFO
Mar 7 — Mar 141
1 adult, Economy
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Find cheap flights from Key Largo to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Key Largo to San Francisco are usually found in May or April, booked 47 days in advance, depart on a Friday or Thursday and return on a Monday
Cheap flight deals from Key Largo to San Francisco
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Best
Last-minute
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Cheapest flights from Key Largo to San FranciscoExplore the most affordable flight options available from Key Largo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.
Explore the most affordable flight options available from Key Largo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:10 pm
MIA
- SFO
1 stop11h 06m
United Airlines
Mon 3/911:00 pm
SFO
- MIA
Nonstop5h 27m
United Airlines
Deal found 2/4![United Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:05 am
MIA
- SFO
1 stop17h 34m
Multiple Airlines
Mon 3/210:58 pm
SFO
- MIA
1 stop8h 30m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:01 pm
MIA
- SFO
2 stops19h 16m
Multiple Airlines
Mon 3/210:58 pm
SFO
- MIA
1 stop8h 30m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:05 am
MIA
- SFO
1 stop18h 16m
Multiple Airlines
Tue 3/1010:40 pm
SFO
- MIA
1 stop8h 54m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$208
This Frontier deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:35 am
MIA
- SFO
1 stop13h 04m
Frontier
Tue 3/310:55 pm
SFO
- MIA
1 stop8h 33m
Frontier
Deal found 2/5![Frontier logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:45 am
MIA
- SFO
1 stop20h 43m
Frontier
Sun 3/810:40 pm
SFO
- MIA
1 stop16h 13m
Frontier
Deal found 2/2![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:05 am
MIA
- SFO
1 stop19h 34m
Frontier
Sat 3/76:33 pm
SFO
- MIA
2 stops25h 36m
Frontier
Deal found 2/5![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:04 pm
MIA
- SFO
1 stop27h 16m
Frontier
Mon 3/910:38 pm
SFO
- MIA
1 stop8h 56m
Frontier
Deal found 2/3![Frontier logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:01 pm
MIA
- SFO
2 stops19h 16m
Multiple Airlines
Sun 2/228:48 am
SFO
- MIA
1 stop17h 26m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:09 pm
MIA
- SFO
1 stop29h 30m
Multiple Airlines
Mon 3/910:38 pm
SFO
- MIA
1 stop10h 38m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:04 pm
MIA
- SFO
1 stop27h 10m
Multiple Airlines
Mon 3/1610:38 pm
SFO
- MIA
1 stop18h 29m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:35 am
MIA
- SFO
1 stop13h 04m
Frontier
Sun 2/2210:46 pm
SFO
- MIA
1 stop8h 42m
Frontier
Deal found 2/2![Frontier logo]()
$216
Best flights from Key Largo to San FranciscoDiscover carefully curated flight deals from Key Largo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 5, 2026.
Discover carefully curated flight deals from Key Largo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 5, 2026.
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:45 am
MIA
- SFO
1 stop9h 12m
United Airlines
Sun 2/2211:00 pm
SFO
- MIA
Nonstop5h 27m
United Airlines
Deal found 2/1![United Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:01 pm
MIA
- SFO
1 stop8h 48m
Delta
Wed 3/185:50 am
SFO
- MIA
1 stop8h 18m
Delta
Deal found 2/5![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:35 am
MIA
- SFO
1 stop8h 48m
United Airlines
Mon 3/3011:05 pm
SFO
- MIA
Nonstop5h 49m
United Airlines
Deal found 2/1![United Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:04 am
MIA
- SFO
1 stop9h 51m
Delta
Sun 5/310:35 pm
SFO
- MIA
1 stop7h 43m
Delta
Deal found 2/4![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:35 am
MIA
- SFO
Nonstop6h 36m
United Airlines
Tue 3/108:32 am
SFO
- MIA
Nonstop5h 24m
United Airlines
Deal found 2/3![United Airlines logo]()
$237
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:15 am
MIA
- SFO
1 stop8h 56m
United Airlines
Tue 3/108:32 am
SFO
- MIA
Nonstop5h 24m
United Airlines
Deal found 2/3![United Airlines logo]()
$247
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/182:55 pm
MIA
- SFO
1 stop11h 52m
Delta
Fri 2/276:55 pm
SFO
- MIA
1 stop8h 40m
Delta
Deal found 2/4![Delta logo]()
$278
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:58 am
MIA
- SFO
1 stop11h 06m
United Airlines
Sat 2/2111:00 pm
SFO
- MIA
Nonstop5h 27m
United Airlines
Deal found 2/4![United Airlines logo]()
$247
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/77:23 am
MIA
- SFO
Nonstop6h 36m
United Airlines
Wed 3/118:32 am
SFO
- MIA
Nonstop5h 24m
United Airlines
Deal found 2/4![United Airlines logo]()
$266
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:15 am
MIA
- SFO
Nonstop6h 31m
United Airlines
Sun 4/266:40 am
SFO
- MIA
1 stop10h 14m
United Airlines
Deal found 2/4![United Airlines logo]()
$268
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:00 am
MIA
- SFO
Nonstop6h 30m
United Airlines
Sun 3/156:40 pm
SFO
- MIA
1 stop8h 11m
United Airlines
Deal found 2/4![United Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/77:23 am
MIA
- SFO
Nonstop6h 36m
United Airlines
Mon 3/910:45 pm
SFO
- MIA
1 stop9h 41m
United Airlines
Deal found 2/4![United Airlines logo]()
$273
Last-minute flights from Key Largo to San FranciscoDiscover last-minute flight deals from Key Largo to San Francisco. Data last updated February 5, 2026 and is based on user searches.
Discover last-minute flight deals from Key Largo to San Francisco. Data last updated February 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:09 pm
MIA
- SFO
1 stop29h 30m
Multiple Airlines
Mon 3/910:38 pm
SFO
- MIA
1 stop10h 38m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:01 pm
MIA
- SFO
2 stops19h 16m
Multiple Airlines
Mon 3/210:58 pm
SFO
- MIA
1 stop8h 30m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:01 pm
MIA
- SFO
2 stops19h 16m
Multiple Airlines
Sun 2/228:48 am
SFO
- MIA
1 stop17h 26m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:35 am
MIA
- SFO
1 stop13h 04m
Frontier
Wed 3/410:58 pm
SFO
- MIA
1 stop8h 30m
Frontier
Deal found 2/2![Frontier logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:35 am
MIA
- SFO
1 stop13h 04m
Frontier
Sun 2/2210:46 pm
SFO
- MIA
1 stop8h 42m
Frontier
Deal found 2/2![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:05 am
MIA
- SFO
1 stop19h 34m
Frontier
Sat 3/76:33 pm
SFO
- MIA
2 stops25h 36m
Frontier
Deal found 2/5![Frontier logo]()
$211
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:35 am
MIA
- SFO
1 stop13h 04m
Frontier
Tue 3/310:55 pm
SFO
- MIA
1 stop8h 33m
Frontier
Deal found 2/2![Frontier logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:05 am
MIA
- SFO
1 stop18h 16m
Multiple Airlines
Tue 3/1010:40 pm
SFO
- MIA
1 stop8h 54m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$208
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:10 pm
MIA
- SFO
1 stop11h 06m
United Airlines
Mon 3/911:00 pm
SFO
- MIA
Nonstop5h 27m
United Airlines
Deal found 2/4![United Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:45 am
MIA
- SFO
1 stop20h 43m
Frontier
Sun 3/810:40 pm
SFO
- MIA
1 stop16h 13m
Frontier
Deal found 2/2![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:04 pm
MIA
- SFO
1 stop27h 16m
Frontier
Mon 3/910:38 pm
SFO
- MIA
1 stop8h 56m
Frontier
Deal found 2/3![Frontier logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:04 pm
MIA
- SFO
1 stop27h 10m
Multiple Airlines
Mon 3/1610:38 pm
SFO
- MIA
1 stop18h 29m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$215
One-way flights from Key Largo to San FranciscoSearch for one-way flight options from Key Largo to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.
Search for one-way flight options from Key Largo to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:01 pm
MIA
- SFO
2 stops19h 16m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$116
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:05 am
MIA
- SFO
2 stops15h 53m
Frontier
Deal found 2/2![Frontier logo]()
$117
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:26 pm
MIA
- SFO
1 stop9h 48m
Frontier
Deal found 2/3![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:35 pm
MIA
- SFO
2 stops27h 33m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$120
This Expedia deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:26 pm
MIA
- SFO
1 stop9h 48m
Frontier
Deal found 2/3![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:05 am
MIA
- SFO
1 stop17h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$122
This Super.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1112:10 pm
MIA
- SFO
1 stop12h 29m
Frontier
Deal found 2/2![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:45 pm
MIA
- SFO
1 stop31h 46m
Frontier
Deal found 2/3![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/77:05 am
MIA
- SFO
3 stops20h 23m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:35 pm
MIA
- SFO
2 stops41h 31m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$126
Find flight deals from Key Largo to San Francisco
Keep the following information in mind while searching for Key Largo to San Francisco flight deals. Data was last updated February 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $203 (Kiwi.com) |
One-way from | $116 (Kiwi.com) |
Popular in | June |
Cheapest in | May |
Average price | $337 |
Cheapflights Fare Finder
Customize your flight search to find flights from Key Largo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Key Largo to San Francisco that are best for you.
Fly from
Key Largo
Fly to
San Francisco
Route
Depart
Return
Price
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Thu 2/19
8:45 am-2:57 pm
1 stop9h 12m
San Francisco
Sun 2/22
11:00 pm-7:27 am
Nonstop5h 27m
$219
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Thu 3/26
9:35 am-3:23 pm
1 stop8h 48m
San Francisco
Mon 3/30
11:05 pm-7:54 am
Nonstop5h 49m
$219
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Tue 3/3
8:35 am-12:11 pm
Nonstop6h 36m
San Francisco
Tue 3/10
8:32 am-4:56 pm
Nonstop5h 24m
$237
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Sat 2/28
6:15 am-12:11 pm
1 stop8h 56m
San Francisco
Tue 3/10
8:32 am-4:56 pm
Nonstop5h 24m
$247
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Wed 2/18
10:58 am-7:04 pm
1 stop11h 06m
San Francisco
Sat 2/21
11:00 pm-7:27 am
Nonstop5h 27m
$247
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Tue 3/3
6:01 pm-11:49 pm
1 stop8h 48m
San Francisco
Wed 3/18
5:50 am-5:08 pm
1 stop8h 18m
$257
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Fri 4/24
8:04 am-2:55 pm
1 stop9h 51m
San Francisco
Sun 5/3
10:35 pm-9:18 am
1 stop7h 43m
$257
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Sat 3/7
7:23 am-10:59 am
Nonstop6h 36m
San Francisco
Wed 3/11
8:32 am-4:56 pm
Nonstop5h 24m
$266
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Sat 4/18
7:15 am-10:46 am
Nonstop6h 31m
San Francisco
Sun 4/26
6:40 am-7:54 pm
1 stop10h 14m
$268
MiamiSan Francisco
MIA - SFO
MIASFO
Miami
Thu 3/12
7:00 am-10:30 am
Nonstop6h 30m
San Francisco
Sun 3/15
6:40 pm-5:51 am
1 stop8h 11m
$269
Showing 1-10 of 23 results
Best time to book a flight from Key Largo to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Key Largo with our price prediction graph.
MIA-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Key Largo to San Francisco
KE9-SFO
MIA-SFO
How far ahead should I book a flight from Key Largo to San Francisco?
Use this chart to determine the optimal time to book a round-trip flight from Key Largo to San Francisco. Price data was last updated on January 30, 2026.
The price you pay for your flight from Key Largo to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 43 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Key Largo to San Francisco?
Currently, March is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $94). Flying from Key Largo to San Francisco in August is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from KE9 to SFO?
Find hourly flight availability from Key Largo to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 5, 2026.
When flying from Key Largo to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Key Largo to San Francisco
Explore weekly flight availability from Key Largo to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 5, 2026.
The most flights from KE9 to SFO are scheduled on a Saturday (26 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (21 on average).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated February 5, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Key Largo to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Key Largo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Roseville
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
San Lorenzo
Davis
Hollister
Redwood City
Manteca
Union City
Elk Grove
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Key Largo to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Key Largo to San Francisco by cabin class
Find flights from Key Largo to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Key Largo and San Francisco flights
Browse other Key Largo and San Francisco flight options. Last updated on February 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 5, 2026.
Key Largo to San Francisco flights
Consider these flights traveling from Key Largo to San Francisco.
Top 6 airlines flying from Key Largo to San Francisco
Discover the top 6 airlines that operate flights from Key Largo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$85 | Average$191 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$128 | Average$277 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$168 | Average$300 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$179 | Average$337 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$332 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$250 | Average$357 | FlexibilityNo cancel fee | On-time63% |