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$129+ Cheap flights from Key Largo, FL to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — SFO
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to San Francisco are usually found in May or January, booked 28 days in advance, depart on a Friday or Thursday and return on a Monday

Cheap flight deals from Key Largo to San Francisco

Cheapest flights from Key Largo to San Francisco
Explore the most affordable flight options available from Key Largo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 9, 2025.

This Mytrip deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:05 amMIA - SFO
1 stop27h 43mFrontier
Mon 1/56:00 amSFO - MIA
1 stop20h 35mFrontier
Deal found 12/9$237
This Mytrip deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amMIA - SFO
1 stop29h 23mFrontier
Thu 1/226:15 amSFO - MIA
1 stop7h 22mFrontier
Deal found 12/8$239
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:20 amMIA - SFO
1 stop8h 54mUnited Airlines
Wed 1/711:18 pmSFO - MIA
Nonstop5h 33mUnited Airlines
Deal found 12/8$255
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amMIA - SFO
1 stop21h 24mFrontier
Thu 1/226:15 amSFO - MIA
1 stop7h 22mFrontier
Deal found 12/8$261
This Mytrip deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amMIA - SFO
1 stop29h 23mFrontier
Wed 1/77:00 amSFO - MIA
1 stop25h 57mFrontier
Deal found 12/8$263
This Super.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amMIA - SFO
1 stop29h 23mFrontier
Mon 1/56:00 amSFO - MIA
1 stop20h 35mFrontier
Deal found 12/9$265
This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:33 pmMIA - SFO
1 stop8h 26mUnited Airlines
Mon 1/511:03 pmSFO - MIA
Nonstop5h 33mUnited Airlines
Deal found 12/6$269
This Super.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:30 amMIA - SFO
1 stop10h 43mFrontier
Fri 12/2611:20 pmSFO - MIA
1 stop8h 38mFrontier
Deal found 12/7$275
This Frontier deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:05 amMIA - SFO
1 stop8h 29mFrontier
Fri 1/24:06 pmSFO - MIA
1 stop10h 29mFrontier
Deal found 12/8$278
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:05 amMIA - SFO
1 stop27h 43mFrontier
Mon 12/296:00 amSFO - MIA
1 stop20h 35mFrontier
Deal found 12/8$280

Find flight deals from Key Largo to San Francisco

Keep the following information in mind while searching for Key Largo to San Francisco flight deals. Data was last updated December 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$226
(Kiwi.com)

One-way from

$129
(Kiwi.com)

Popular in

June

Cheapest in

May

Average price

$362
Provider with most accurate pricing for Miami-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Miami-San Francisco flights.
Search Deals
From Key Largo to San Francisco
Search Deals
One-way flight from Key Largo to San Francisco
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($7 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Key Largo to San Francisco that are best for you.

Fly from

Key Largo

Fly to

San Francisco

Route

Depart

Return

Price

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 1/17

6:05 am-9:43 am

Nonstop6h 38m

San Francisco

Sat 1/24

8:30 am-5:06 pm

Nonstop5h 36m

$231

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sun 2/8

6:20 am-12:20 pm

1 stop9h 00m

San Francisco

Tue 2/10

8:30 am-5:06 pm

Nonstop5h 36m

$255

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 1/13

11:05 am-4:50 pm

1 stop8h 45m

San Francisco

Mon 2/2

8:30 am-5:06 pm

Nonstop5h 36m

$255

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 1/17

7:00 am-7:10 pm

1 stop15h 10m

San Francisco

Sat 1/24

10:25 am-9:30 pm

1 stop8h 05m

$256

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 2/3

7:39 am-4:05 pm

1 stop11h 26m

San Francisco

Sat 2/7

9:30 pm-9:24 am

1 stop8h 54m

$257

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Fri 1/16

6:05 am-9:43 am

Nonstop6h 38m

San Francisco

Mon 1/19

11:18 pm-7:51 am

Nonstop5h 33m

$259

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Fri 1/23

6:05 am-9:43 am

Nonstop6h 38m

San Francisco

Mon 1/26

11:18 pm-7:51 am

Nonstop5h 33m

$259

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 3/7

7:23 am-10:59 am

Nonstop6h 36m

San Francisco

Tue 3/10

8:32 am-4:56 pm

Nonstop5h 24m

$259

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Fri 2/27

7:50 am-3:03 pm

1 stop10h 13m

San Francisco

Tue 3/3

10:54 pm-10:21 am

1 stop8h 27m

$268

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 1/8

4:19 pm-11:00 pm

1 stop9h 41m

San Francisco

Mon 1/12

11:18 pm-7:51 am

Nonstop5h 33m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 20 results
1
2

Best time to book a flight from Key Largo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to San Francisco

How far ahead should I book a flight from Key Largo to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to San Francisco. Price data was last updated on December 5, 2025.

The price you pay for your flight from Key Largo to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 28 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Key Largo to San Francisco?

Currently, June is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $89). Flying from Key Largo to San Francisco in August is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SFO?

Find hourly flight availability from Key Largo to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 9, 2025.

One of the essential ways to save on airfare from Key Largo to San Francisco is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 62% on airfare.

What is the cheapest day to fly from Key Largo to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to San Francisco flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to San Francisco

Explore weekly flight availability from Key Largo to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 9, 2025.

The most flights from KE9 to SFO are scheduled on a Monday (23 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (20 on average).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated December 9, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Key Largo to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
JetBlue
7.2
Good
2,899 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
5.8
Fair
3,085 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Key Largo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Key Largo?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Key Largo to San Francisco. 6 airlines have flights to San Francisco from Key Largo on a regular basis. Booking flights from Key Largo to San Francisco should not be difficult; the airport handles an average of 21 inbound flights from Key Largo per day.

  • How popular is this Key Largo to San Francisco flight route?

    The Key Largo to San Francisco flight path was viewed by 81 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Key Largo to San Francisco?

    Departing from Key Largo to San Francisco will take you 6h 38m. The distance from Key Largo to San Francisco is about 2579 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to San Francisco one-way?

    The cheapest airlines for a one-way flight from Key Largo to San Francisco are Frontier ($82), JetBlue ($89), and American Airlines ($111).

  • What are the most reliable airlines from Key Largo to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Key Largo to San Francisco consider choosing Royal Air Maroc (100%), Japan Airlines (93%) or Air New Zealand (90%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Key Largo to San Francisco?

    Looking for the cheapest flight from Key Largo to San Francisco? While on average our users pay $1,021, our data indicates the cheapest price to be $129. The most popular route (Miami - San Francisco), is priced around $153.

  • Can I find deals for flights from Key Largo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Key Largo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to San Francisco.

  • Can I find deals for business class flights from Key Largo to San Francisco?

    Yes. Cheapflights offers flight deals from Key Largo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to San Francisco?

    Currently, June is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $89). Flying from Key Largo to San Francisco in August is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
San Bruno
Redwood City
Daly City
Vallejo
Hollister
Foster City
Union City
Davis
San Ramon
Burlingame
Milpitas

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Top 6 airlines flying from Key Largo to San Francisco

Discover the top 6 airlines that operate flights from Key Largo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$116Average$177FlexibilityNo cancel feeOn-time62%
DeltaCheapest$128Average$276FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$181Average$312FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$185Average$337FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$217Average$303FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$218Average$367FlexibilityNo cancel feeOn-time71%

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