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$126+ Cheap flights from Key Largo, FL to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — SFO
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to San Francisco are usually found in January or August, booked 70 days in advance, depart on a Thursday or Wednesday and return on a Monday

Cheap flight deals from Key Largo to San Francisco

Keep the following information in mind while searching for Key Largo to San Francisco flight deals. Data was last updated June 12, 2025.

Round-trip from

$237
(American Airlines)

One-way from

$126
(United Airlines)

Popular in

June

Cheapest in

January

Average price

$405
From Key Largo to San Francisco
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One-way flight from Key Largo to San Francisco
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Highest demand for flights based on searches. 10% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Key Largo to San Francisco

Cheapest flights from Key Largo to San Francisco
Explore the most affordable flight options available from Key Largo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/27:30 pmMIA - SFO
Nonstop6h 08mAmerican Airlines
Tue 7/88:00 amSFO - MIA
Nonstop5h 40mAmerican Airlines
Deal found 6/10$237
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/224:10 pmMIA - SFO
1 stop8h 05mSouthwest
Tue 8/269:05 pmSFO - MIA
1 stop10h 50mSouthwest
Deal found 6/11$238
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/219:00 amMIA - SFO
1 stop10h 47mUnited Airlines
Thu 11/2711:05 pmSFO - MIA
Nonstop5h 30mUnited Airlines
Deal found 6/10$239
This FlightHub deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/86:00 amMIA - SFO
1 stop21h 19mFrontier
Fri 8/156:37 amSFO - MIA
1 stop20h 53mFrontier
Deal found 6/12$245
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/214:25 pmMIA - SFO
1 stop11h 10mDelta
Thu 9/45:55 amSFO - MIA
1 stop8h 29mDelta
Deal found 6/10$257
This Alaska Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/126:20 pmMIA - SFO
2 stops17h 29mAlaska Airlines
Sat 8/166:53 pmSFO - MIA
1 stop19h 27mAlaska Airlines
Deal found 6/10$310
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2511:11 amMIA - SFO
2 stops14h 42mMultiple Airlines
Fri 8/111:59 pmSFO - MIA
1 stop8h 11mMultiple Airlines
Deal found 6/10$375

Cheapflights Fare Finder

Customize your flight search to find flights from Key Largo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Key Largo to San Francisco that are best for you.

Fly from

Key Largo

Fly to

San Francisco

Route

Depart

Return

Price

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 7/2

7:30 pm-10:38 pm

Nonstop6h 08m

San Francisco

Tue 7/8

8:00 am-4:40 pm

Nonstop5h 40m

$237

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Fri 8/22

4:10 pm-9:15 pm

1 stop8h 05m

San Francisco

Tue 8/26

9:05 pm-10:55 am

1 stop10h 50m

$238

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 6/25

8:41 am-11:44 am

Nonstop6h 03m

San Francisco

Tue 7/8

6:00 am-7:39 pm

1 stop10h 39m

$243

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Fri 8/8

6:00 am-12:19 am

1 stop21h 19m

San Francisco

Fri 8/15

6:37 am-6:30 am

1 stop20h 53m

$245

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 8/21

4:25 pm-12:35 am

1 stop11h 10m

San Francisco

Thu 9/4

5:55 am-5:24 pm

1 stop8h 29m

$257

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 8/12

6:20 pm-8:49 am

2 stops17h 29m

San Francisco

Sat 8/16

6:53 pm-5:20 pm

1 stop19h 27m

$310

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Fri 7/25

11:11 am-10:53 pm

2 stops14h 42m

San Francisco

Fri 8/1

11:59 pm-11:10 am

1 stop8h 11m

$375

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 9/9

10:58 am-5:41 pm

1 stop9h 43m

$126

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 7/16

6:34 pm-12:03 am

1 stop8h 29m

$129

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Fri 8/22

7:55 pm-10:59 pm

Nonstop6h 04m

$130

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 15 results
1
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Best time to book a flight from Key Largo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to San Francisco

How far ahead should I book a flight from Key Largo to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to San Francisco. Price data was last updated on June 9, 2025.

The price you pay for your flight from Key Largo to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 70 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Key Largo to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $276). Flying from Key Largo to San Francisco in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SFO?

Find hourly flight availability from Key Largo to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Key Largo to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to San Francisco flight should consider departing on Thursday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to San Francisco

Explore weekly flight availability from Key Largo to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 12, 2025.

The most flights from KE9 to SFO are scheduled on a Thursday (28 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (16 on average).

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 12, 2025.
To help decide which airline to fly from Key Largo to San Francisco, see what other customers have to say about Alaska Airlines, Southwest and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Key Largo?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Key Largo to San Francisco. 6 airlines have flights to San Francisco from Key Largo on a regular basis. Booking flights from Key Largo to San Francisco should not be difficult; the airport handles an average of 23 inbound flights from Key Largo per day.

  • How popular is this Key Largo to San Francisco flight route?

    The Key Largo to San Francisco flight path was viewed by 59 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Key Largo to San Francisco one-way?

    The cheapest airlines for a one-way flight from Key Largo to San Francisco are United Airlines ($126), Delta ($129), and American Airlines ($130).

  • What are the most reliable airlines from Key Largo to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Key Largo to San Francisco consider choosing Cathay Pacific (91%), Virgin Australia (90%) or Royal Air Maroc (89%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Key Largo to San Francisco?

    Looking for the cheapest flight from Key Largo to San Francisco? While on average our users pay $1,699, our data indicates the cheapest price to be $118. The most popular route (Miami - San Francisco), is priced around $177.

  • Can I find deals for flights from Key Largo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Key Largo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to San Francisco.

  • Can I find deals for business class flights from Key Largo to San Francisco?

    Yes. Cheapflights offers flight deals from Key Largo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $276). Flying from Key Largo to San Francisco in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Key Largo?

Book flights to Key Largo if you plan to visit one of these locations
Roseville
Mountain View
South San Francisco
Livermore
Turlock
Santa Cruz
Manteca
Fairfield
Watsonville
Antioch
Hollister
Milpitas
Newark
Hayward
Alameda
Sunnyvale
Daly City
Union City
Campbell
Capitola

Browse thousands of different options on Cheapflights for your next trip

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Top 6 airlines flying from Key Largo to San Francisco

Discover the top 6 airlines that operate flights from Key Largo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$81Average$171FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$99Average$286FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$109Average$381FlexibilityNo cancel feeOn-time71%
DeltaCheapest$128Average$272FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$178Average$340FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$188Average$306FlexibilityNo cancel feeOn-time75%

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