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$116+ Cheap flights from Indiana to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SFO
Jun 17 — Jun 241
Wed 6/17
Wed 6/24
1 adult, Economy
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Cheap flight deals from Indiana to San Francisco

Cheapest flights from Indiana to San Francisco
Explore the most affordable flight options available from Indiana to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.

This Mytrip deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:31 am
SDF
-
SFO
Nonstop5h 02m
Breeze Airways
Fri 9/1111:54 am
SFO
-
SDF
Nonstop4h 25m
Breeze Airways
Deal found 5/15$219
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:21 am
SDF
-
SFO
1 stop14h 39m
Multiple Airlines
Fri 9/1111:54 am
SFO
-
SDF
Nonstop4h 25m
Multiple Airlines
Deal found 5/15$259
This Booking.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:31 am
SDF
-
SFO
Nonstop5h 02m
Breeze Airways
Fri 8/1412:18 pm
SFO
-
SDF
Nonstop4h 30m
Breeze Airways
Deal found 5/16$267
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:05 am
SBN
-
SFO
1 stop7h 23m
Delta
Wed 8/126:00 am
SFO
-
SBN
1 stop7h 28m
Delta
Deal found 5/14$273
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:00 pm
CVG
-
SFO
1 stop14h 43m
Frontier
Wed 8/1211:10 am
SFO
-
CVG
2 stops29h 38m
Frontier
Deal found 5/16$273
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:05 am
ORD
-
SFO
1 stop14h 08m
Frontier
Mon 7/2010:56 pm
SFO
-
ORD
1 stop28h 32m
Frontier
Deal found 5/13$273
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:00 am
ORD
-
SFO
1 stop7h 39m
Multiple Airlines
Thu 9/109:00 pm
SFO
-
ORD
1 stop6h 42m
Multiple Airlines
Deal found 5/13$275
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:57 pm
CVG
-
SFO
1 stop29h 01m
Multiple Airlines
Wed 8/511:10 am
SFO
-
CVG
2 stops29h 38m
Multiple Airlines
Deal found 5/17$276
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:50 am
ORD
-
SFO
1 stop8h 31m
Frontier
Sun 11/19:00 pm
SFO
-
ORD
1 stop6h 35m
Frontier
Deal found 5/14$276
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:31 am
SDF
-
SFO
Nonstop5h 02m
Breeze Airways
Mon 9/712:18 pm
SFO
-
SDF
Nonstop4h 30m
Breeze Airways
Deal found 5/15$277
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
MDW
-
SFO
1 stop9h 21m
Delta
Tue 9/812:40 am
SFO
-
MDW
1 stop5h 58m
Delta
Deal found 5/13$277
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:30 am
ORD
-
SFO
1 stop7h 05m
Delta
Wed 7/229:55 am
SFO
-
ORD
1 stop7h 02m
Delta
Deal found 5/13$277

Find flight deals from Indiana to San Francisco

Keep the following information in mind while searching for Indiana to San Francisco flight deals. Data was last updated May 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$219
(Mytrip)

One-way from

$116
(Booking.com)

Popular in

March

Cheapest in

September

Average price

$379

Good round-trip deal

$429 or less

Good one-way deal

$303 or less
Provider with most accurate pricing for Indianapolis-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-San Francisco flights.
Search Deals
From Indiana to San Francisco
Search Deals
One-way flight from Indiana to San Francisco
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($17 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals
Price to beat on a round-trip flight from Indiana to San Francisco.
Search Deals
Price to beat on a one-way flight from Indiana to San Francisco.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Indiana to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

South BendSan Francisco

SBN - SFO

SBNSFO

South Bend/Michiana

Wed 7/1

7:10 am-11:35 am

1 stop7h 25m

San Francisco

Sat 7/4

11:45 am-10:26 pm

1 stop7h 41m

$273

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Wed 9/2

1:05 pm-7:24 pm

1 stop8h 19m

San Francisco

Mon 9/7

12:40 am-8:38 am

1 stop5h 58m

$277

ChicagoSan Francisco

ORD - SFO

ORDSFO

Chicago O'Hare Intl

Sat 6/6

7:00 am-2:15 pm

1 stop9h 15m

San Francisco

Wed 8/26

10:59 pm-7:56 am

1 stop6h 57m

$292

ChicagoSan Francisco

ORD - SFO

ORDSFO

Chicago O'Hare Intl

Wed 6/3

7:45 pm-12:27 am

1 stop6h 42m

San Francisco

Sat 8/29

6:06 am-2:57 pm

1 stop6h 51m

$292

ChicagoSan Francisco

ORD - SFO

ORDSFO

Chicago O'Hare Intl

Wed 6/10

9:48 pm-12:45 am

Nonstop4h 57m

San Francisco

Fri 6/12

12:50 am-7:16 am

Nonstop4h 26m

$296

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Sat 9/5

9:30 am-2:29 pm

1 stop6h 59m

San Francisco

Sat 9/5

11:45 pm-9:50 am

1 stop8h 05m

$307

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Tue 6/23

6:00 am-1:40 pm

1 stop9h 40m

San Francisco

Tue 6/30

5:15 am-11:25 am

Nonstop4h 10m

$315

ChicagoSan Francisco

MDW - SFO

MDWSFO

Chicago Midway

Mon 6/29

5:45 am-11:10 am

1 stop7h 25m

San Francisco

Tue 7/7

5:00 am-2:35 pm

2 stops7h 35m

$321

ChicagoSan Francisco

ORD - SFO

ORDSFO

Chicago O'Hare Intl

Fri 6/12

7:37 pm-11:58 pm

1 stop6h 21m

San Francisco

Tue 6/16

6:00 am-3:05 pm

1 stop7h 05m

$325

IndianapolisSan Francisco

IND - SFO

INDSFO

Indianapolis

Wed 10/21

6:23 pm-8:10 pm

Nonstop4h 47m

San Francisco

Sun 10/25

9:00 pm-4:33 am

Nonstop4h 33m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/14

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Indiana to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to San Francisco

How far ahead should I book a flight from Indiana to San Francisco?

The price you pay for your flight from Indiana to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 65 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Indiana to San Francisco?

Currently, April is the cheapest month in which you can book a flight from Indiana to San Francisco (average of $105). Flying from Indiana to San Francisco in February is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SFO?

Find hourly flight availability from Indiana to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 18, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indiana to San Francisco as you normally would.

How much does it cost to fly round-trip from Indiana to San Francisco?

Related info for your journey

Find useful and relevant information for your journey from Indiana to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Indiana?

    San Francisco (SFO), located 11.0 mi from the city center, is the airport you fly into when you book flights from Indiana to San Francisco.

  • How popular is this Indiana to San Francisco flight route?

    Flights from Indiana to San Francisco have been viewed 36 times in the past calendar month.

  • How long is the flight from Indiana to San Francisco?

    A quick flight from Indiana to San Francisco can take about 4h 57m. Delta provides one of the quickest options available for as low as $296. There are 1841 mi between Indiana and San Francisco. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to San Francisco one-way?

    One-way options have recently been found by users for as low as $89 on Frontier. Other airlines that offer cheap prices include Delta from $118 and Alaska Airlines from $124 one-way.

  • What are the most popular routes from Indiana to San Francisco?

    The most popular route from Indiana to San Francisco is Chicago O'Hare Intl - San Francisco. You may also consider Indianapolis - San Francisco or Chicago Midway - San Francisco.

  • What are the most reliable airlines from Indiana to San Francisco?

    Before booking your flight to San Francisco from Indiana, check out the most reliable airlines to get you to your destination on time: United Airlines (71%), Virgin Australia (69%), Air New Zealand( 69%).

  • What are the cheapest flights from Indiana to San Francisco?

    On average you can expect to pay $608 for a flight from Indiana to San Francisco. The cheapest flight overall is $198 while the most popular route, (Chicago O'Hare Intl - San Francisco) is currently priced at $257.

  • Can I find deals for flights from Indiana to San Francisco that include hotel bookings?

    Yes. In addition to deals on Indiana to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to San Francisco.

  • Can I find deals for business class flights from Indiana to San Francisco?

    Yes. Cheapflights offers flight deals from Indiana to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to San Francisco?

    Currently, April is the cheapest month in which you can book a flight from Indiana to San Francisco (average of $105). Flying from Indiana to San Francisco in February is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
Vallejo
San Lorenzo
Davis
Emeryville
Manteca
Elk Grove

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Alternative routes for Indiana to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indiana to San Francisco

Discover the top 6 airlines that operate flights from Indiana to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$107Average$273FlexibilityNo cancel feeOn-time62%
DeltaCheapest$165Average$372FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$428FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$269Average$426FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$278Average$441FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$284Average$413FlexibilityNo cancel feeOn-time63%

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