$304+ Cheap flights from Guayaquil (GYE) to San Francisco (SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SFO
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from Guayaquil to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guayaquil to San Francisco
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One-way
Cheapest flights from Guayaquil to San FranciscoExplore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:23 am -
1 stop17h 17m
Tue 11/107:36 pm -
1 stop15h 06m
Deal found 9/18![Copa Airlines logo]()
$578
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:50 pm -
2 stops20h 00m
Fri 10/302:15 pm -
2 stops15h 10m
Deal found 9/18![Avianca logo]()
$579
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:35 pm -
2 stops19h 20m
Tue 11/1011:00 pm -
2 stops16h 25m
Deal found 9/18![Avianca logo]()
$602
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:29 pm -
2 stops20h 32m
Sat 11/148:35 am -
1 stop11h 41m
Deal found 9/19![American Airlines logo]()
$613
This Trip.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:05 am -
2 stops28h 45m
Thu 9/242:30 am -
2 stops19h 00m
Deal found 9/19![Avianca logo]()
$614
This oojo deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:38 pm -
1 stop25h 47m
Sun 11/2912:33 am -
1 stop10h 09m
Deal found 9/20![Copa Airlines logo]()
$626
This FlightHub deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:50 pm -
2 stops20h 00m
Sat 10/2411:55 pm -
2 stops21h 40m
Deal found 9/19![Avianca logo]()
$627
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:55 pm -
2 stops17h 55m
Tue 10/132:15 pm -
2 stops16h 40m
Deal found 9/19![Avianca logo]()
$628
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:05 am -
2 stops15h 50m
Mon 10/1911:55 pm -
2 stops31h 00m
Deal found 9/18![Avianca logo]()
$665
This Orbitz deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:55 pm -
1 stop19h 54m
Tue 10/272:55 pm -
1 stop19h 08m
Deal found 9/21![JetBlue logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:40 pm -
1 stop25h 45m
Wed 11/47:25 pm -
2 stops25h 30m
Deal found 9/21![Multiple Airlines logo]()
$675
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:01 am -
1 stop19h 39m
Sun 11/157:36 pm -
1 stop12h 42m
Deal found 9/19![Copa Airlines logo]()
$690
Best flights from Guayaquil to San FranciscoDiscover carefully curated flight deals from Guayaquil to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Guayaquil to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/188:25 am -
1 stop12h 00m
Tue 1/267:36 pm -
1 stop15h 08m
Deal found 9/20![Copa Airlines logo]()
$578
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:35 pm -
2 stops19h 20m
Tue 11/1011:00 pm -
2 stops16h 25m
Deal found 9/18![Avianca logo]()
$602
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/183:31 pm -
2 stops20h 29m
Wed 2/2412:29 am -
2 stops19h 13m
Deal found 9/18![American Airlines logo]()
$608
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:23 am -
1 stop17h 17m
Tue 11/107:36 pm -
1 stop15h 06m
Deal found 9/18![Copa Airlines logo]()
$578
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:25 am -
1 stop12h 00m
Wed 11/117:36 pm -
1 stop22h 20m
Deal found 9/20![Copa Airlines logo]()
$578
This Avianca deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:05 am -
2 stops15h 50m
Mon 10/1911:55 pm -
2 stops31h 00m
Deal found 9/22![Avianca logo]()
$665
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/174:22 am -
1 stop21h 55m
Thu 2/257:36 pm -
1 stop15h 07m
Deal found 9/20![Copa Airlines logo]()
$612
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:55 pm -
2 stops17h 55m
Tue 10/132:15 pm -
2 stops16h 40m
Deal found 9/18![Avianca logo]()
$703
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:24 am -
1 stop17h 16m
Thu 10/291:31 am -
1 stop10h 09m
Deal found 9/20![Copa Airlines logo]()
$704
Last-minute flights from Guayaquil to San FranciscoDiscover last-minute flight deals from Guayaquil to San Francisco. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to San Francisco. Data last updated September 23, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:05 am -
2 stops28h 45m
Thu 9/242:30 am -
2 stops19h 00m
Deal found 9/19![Avianca logo]()
$614
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:55 pm -
2 stops17h 55m
Tue 10/132:15 pm -
2 stops16h 40m
Deal found 9/19![Avianca logo]()
$628
This FlightHub deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:50 pm -
2 stops20h 00m
Sat 10/2411:55 pm -
2 stops21h 40m
Deal found 9/19![Avianca logo]()
$627
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:05 am -
2 stops15h 50m
Mon 10/1911:55 pm -
2 stops31h 00m
Deal found 9/18![Avianca logo]()
$665
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:50 pm -
2 stops20h 00m
Fri 10/302:15 pm -
2 stops15h 10m
Deal found 9/18![Avianca logo]()
$579
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:01 am -
1 stop19h 39m
Sun 11/157:36 pm -
1 stop12h 42m
Deal found 9/19![Copa Airlines logo]()
$690
This Orbitz deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:55 pm -
1 stop19h 54m
Tue 10/272:55 pm -
1 stop19h 08m
Deal found 9/21![JetBlue logo]()
$671
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:29 pm -
2 stops20h 32m
Sat 11/148:35 am -
1 stop11h 41m
Deal found 9/19![American Airlines logo]()
$613
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:40 pm -
1 stop25h 45m
Wed 11/47:25 pm -
2 stops25h 30m
Deal found 9/21![Multiple Airlines logo]()
$675
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:23 am -
1 stop17h 17m
Tue 11/107:36 pm -
1 stop15h 06m
Deal found 9/18![Copa Airlines logo]()
$578
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:35 pm -
2 stops19h 20m
Tue 11/1011:00 pm -
2 stops16h 25m
Deal found 9/18![Avianca logo]()
$602
One-way flights from Guayaquil to San FranciscoSearch for one-way flight options from Guayaquil to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Guayaquil to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:30 pm -
1 stop12h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![JetBlue logo]()
$304
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/114:14 am -
1 stop21h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Copa Airlines logo]()
$316
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:15 pm -
2 stops23h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Delta logo]()
$376
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:05 am -
2 stops14h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Avianca logo]()
$378
This BusinessClass deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:35 pm -
2 stops22h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![GOL logo]()
$390
This FlightHub deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:50 pm -
2 stops29h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Avianca logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:18 pm -
3 stops48h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
1 stop19h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:38 pm -
3 stops28h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$414
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:18 am -
3 stops21h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$416
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:45 pm -
2 stops23h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Avianca logo]()
$421
Find flight deals from Guayaquil to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $578 (Copa Airlines) |
One-way from | $304 (Cheapflightsfares) |
Popular in | July |
Cheapest in | January |
Average price | $719 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Sun 10/11
4:14 am-11:40 pm
1 stop21h 26m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$316
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Sat 11/21
6:38 pm-5:25 pm
1 stop25h 47m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$316
Quickest round-trip
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Mon 10/19
4:15 pm-10:29 am
1 stop20h 14m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$376
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Mon 10/19
6:50 pm-10:35 pm
2 stops29h 45m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$402
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Mon 10/12
12:18 pm-11:05 am
3 stops48h 47m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$405
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Mon 1/18
8:25 am-5:25 pm
1 stop12h 00m
San Francisco
Tue 1/26
7:36 pm-1:44 pm
1 stop15h 08m
$578
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Thu 10/29
8:23 am-11:40 pm
1 stop17h 17m
San Francisco
Tue 11/10
7:36 pm-1:42 pm
1 stop15h 06m
$578
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Wed 11/4
8:25 am-5:25 pm
1 stop12h 00m
San Francisco
Wed 11/11
7:36 pm-8:56 pm
1 stop22h 20m
$578
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Thu 10/29
7:35 pm-12:55 pm
2 stops19h 20m
San Francisco
Tue 11/10
11:00 pm-6:25 pm
2 stops16h 25m
$602
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Thu 2/18
3:31 pm-9:00 am
2 stops20h 29m
San Francisco
Wed 2/24
12:29 am-10:42 pm
2 stops19h 13m
$608
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to San Francisco in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Guayaquil-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Guayaquil with our price prediction graph.
GYE-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to San Francisco
How far ahead should I book a flight from Guayaquil to San Francisco?
To ensure you get the cheapest price possible for a flight from Guayaquil to San Francisco, you should look to book at least 71 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Guayaquil to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $432). Flying from Guayaquil to San Francisco in July is currently the most expensive (average of $743). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Guayaquil to San Francisco?
Airfare is typical for this route at the moment.
Guayaquil to San Francisco flights typically cost between $528 and $796 in October.The cheapest round-trip price found within the last 5 days was $578 on Avianca (Oct 29-Nov 2).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 23, 2026.
Peruse reviews from past customers who have flown with Copa Airlines from Guayaquil to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Entertainment
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Crew
8.1
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Food
6.9
Entertainment
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Crew
8.1
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Emeryville
Burlingame
Rancho Cordova
San Bruno
Roseville
Hayward
Cupertino
Newark
Fairfield
San Ramon
Redwood City
Manteca
Vallejo
San Carlos
Turlock
Davis
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Guayaquil and San Francisco flights
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Top airline flying from Guayaquil to San Francisco
Discover the top airline that operate flights from Guayaquil to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$460 | Average$737 | FlexibilityNo cancel fee | On-time70% |