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$214+ Cheap flights from Guayaquil (GYE) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SFO
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Guayaquil to San Francisco

Cheapest flights from Guayaquil to San Francisco
Explore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This LATAM Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:05 am
GYE
-
SFO
2 stops27h 47m
LATAM Airlines
Tue 3/178:00 am
SFO
-
GYE
2 stops22h 02m
LATAM Airlines
Deal found 2/9$408
This SmartFares deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:55 pm
GYE
-
SFO
1 stop20h 52m
JetBlue
Tue 9/812:45 pm
SFO
-
GYE
1 stop14h 20m
JetBlue
Deal found 2/11$418
This Copa Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:28 am
GYE
-
SFO
1 stop17h 12m
Copa Airlines
Sun 5/241:12 am
SFO
-
GYE
1 stop20h 24m
Copa Airlines
Deal found 2/11$422
This Avianca deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:05 am
GYE
-
SFO
2 stops15h 50m
Avianca
Mon 4/202:15 pm
SFO
-
GYE
2 stops16h 40m
Avianca
Deal found 2/9$449
This LATAM Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/114:30 pm
GYE
-
SFO
1 stop25h 20m
LATAM Airlines
Sun 3/12:25 pm
SFO
-
GYE
1 stop13h 55m
LATAM Airlines
Deal found 2/10$457
This Avianca deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:05 am
GYE
-
SFO
2 stops14h 30m
Avianca
Mon 5/252:15 pm
SFO
-
GYE
2 stops18h 00m
Avianca
Deal found 2/10$460
This Priceline deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:25 am
GYE
-
SFO
2 stops15h 55m
Multiple Airlines
Wed 3/118:00 am
SFO
-
GYE
1 stop18h 14m
Multiple Airlines
Deal found 2/10$463
This BusinessClass deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:43 pm
GYE
-
SFO
1 stop10h 57m
Copa Airlines
Mon 4/201:23 am
SFO
-
GYE
1 stop10h 12m
Copa Airlines
Deal found 2/9$469
This Copa Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:28 am
GYE
-
SFO
1 stop17h 12m
Copa Airlines
Sat 5/308:06 pm
SFO
-
GYE
1 stop13h 14m
Copa Airlines
Deal found 2/9$471

Find flight deals from Guayaquil to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$408
(LATAM Airlines)

One-way from

$214
(Delta)

Popular in

August

Cheapest in

November

Average price

$451
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-San Francisco flights.
Search Deals
From Guayaquil Jose Joaquin de Olmedo to San Francisco
Search Deals
One-way flight from Guayaquil Jose Joaquin de Olmedo to San Francisco
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.

Fly from

Guayaquil

Fly to

San Francisco

Route

Depart

Return

Price

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Mon 3/9

9:05 am-10:52 am

2 stops27h 47m

San Francisco

Tue 3/17

8:00 am-8:02 am

2 stops22h 02m

$408

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Mon 4/13

8:28 am-11:40 pm

1 stop17h 12m

San Francisco

Mon 4/20

1:23 am-11:22 am

1 stop31h 59m

$469

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 2/27

8:34 am-7:31 am

2 stops25h 57m

San Francisco

Sun 3/8

12:43 am-8:46 pm

2 stops18h 03m

$478

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 4/15

4:00 pm-10:28 am

1 stop20h 28m

San Francisco

Sun 4/19

10:35 pm-2:40 pm

2 stops38h 05m

$479

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 5/8

8:28 am-11:40 pm

1 stop17h 12m

San Francisco

Fri 5/15

1:12 am-12:01 am

1 stop20h 49m

$483

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 5/15

8:28 am-7:15 am

2 stops24h 47m

San Francisco

Tue 5/19

5:00 am-11:36 pm

2 stops16h 36m

$490

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Tue 5/12

8:28 am-7:15 am

2 stops24h 47m

San Francisco

Mon 5/18

12:45 am-5:29 pm

2 stops14h 44m

$490

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 5/13

12:22 pm-11:59 pm

2 stops13h 37m

San Francisco

Wed 5/20

5:00 am-11:36 pm

2 stops16h 36m

$490

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Mon 5/11

8:28 am-7:15 am

2 stops24h 47m

San Francisco

Sun 5/17

11:59 pm-5:29 pm

2 stops15h 30m

$490

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 5/13

12:22 pm-11:59 pm

2 stops13h 37m

San Francisco

Mon 5/18

12:45 am-8:52 pm

2 stops18h 07m

$490

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 19 results
1
2
  • Most accurate provider: When it comes to deals on Guayaquil-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guayaquil-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guayaquil to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to San Francisco

How far ahead should I book a flight from Guayaquil to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to San Francisco. Price data was last updated on February 6, 2026.

To ensure you get the cheapest price possible for a flight from Guayaquil to San Francisco, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Guayaquil to San Francisco?

Currently, May is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $259). Flying from Guayaquil to San Francisco in August is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated February 12, 2026.
Peruse reviews from past customers who have flown with Copa Airlines, United Airlines, and Avianca from Guayaquil to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,557 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Copa Airlines
7.5
Good
1,557 reviews
Copa Airlines
7.5
Good
1,557 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
United Airlines
7.4
Good
9,279 reviews
Copa Airlines
7.5
Good
1,557 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Avianca
6.5
Okay
2,496 reviews
Copa Airlines
7.5
Good
1,557 reviews

Food

6.8

Entertainment

6.8

Boarding

7.8

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Guayaquil to San Francisco?

    LATAM Airlines, Copa Airlines, and United Airlines can get you from Guayaquil to San Francisco in just under 17h 12m. Your travel time can differ by up to 10h 35m. Guayaquil and San Francisco are separated by a distance of 3860 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Guayaquil to San Francisco round-trip?

    Our cheapest airline available from Guayaquil to San Francisco is Copa Airlines. Our recent data shows that you can find tickets from as low as $295 on this airline. Additional options worth looking into are United Airlines and Avianca, starting at $301 and $463 round-trip. Copa Airlines is currently priced 45% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Guayaquil to San Francisco one-way?

    $262 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on Avianca and United Airlines, with prices starting from $264 and $301, respectively.

  • Can I find deals for flights from Guayaquil to San Francisco that include hotel bookings?

    Yes. In addition to deals on Guayaquil to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to San Francisco.

  • Can I find deals for business class flights from Guayaquil to San Francisco?

    Yes. Cheapflights offers flight deals from Guayaquil to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to San Francisco?

    Currently, May is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $259). Flying from Guayaquil to San Francisco in August is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
South San Francisco
Santa Clara
Roseville
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
Redwood City
Rancho Cordova
San Lorenzo
Davis
Hollister
Manteca
Union City

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Guayaquil to San Francisco

Discover the top 3 airlines that operate flights from Guayaquil to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$295Average$597FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$301Average$356FlexibilityNo cancel feeOn-time69%
AviancaCheapest$463Average$609FlexibilityNo cancel feeOn-time71%

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