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$262+ Cheap flights from Guayaquil (GYE) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SFO
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to San Francisco are usually found in June or May, booked 67 days in advance, depart on a Monday or Tuesday and return on a Sunday

Cheap flight deals from Guayaquil to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$445
(Delta)

One-way from

$262
(Priceline)

Popular in

August

Cheapest in

June

Average price

$557
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-San Francisco flights.
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From Guayaquil Jose Joaquin de Olmedo to San Francisco
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One-way flight from Guayaquil Jose Joaquin de Olmedo to San Francisco
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Highest demand for flights based on searches. 4% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Guayaquil to San Francisco

Cheapest flights from Guayaquil to San Francisco
Explore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:30 pmGYE - SFO
1 stop21h 05mDelta
Wed 1/212:25 pmSFO - GYE
1 stop13h 55mDelta
Deal found 11/4$445
This Expedia deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:31 pmGYE - SFO
1 stop19h 47mJetBlue
Wed 1/218:45 pmSFO - GYE
2 stops15h 35mJetBlue
Deal found 11/4$490
This JetBlue deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:30 amGYE - SFO
1 stop15h 00mJetBlue
Fri 12/2611:54 pmSFO - GYE
1 stop12h 16mJetBlue
Deal found 11/3$502
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/194:40 amGYE - SFO
2 stops20h 10mAvianca
Tue 12/21:35 amSFO - GYE
2 stops19h 00mAvianca
Deal found 11/5$531
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:35 pmGYE - SFO
1 stop32h 54mUnited Airlines
Thu 12/411:59 pmSFO - GYE
2 stops20h 42mUnited Airlines
Deal found 11/3$549
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/42:40 amGYE - SFO
2 stops22h 10mAvianca
Wed 11/1211:10 pmSFO - GYE
2 stops21h 25mAvianca
Deal found 11/4$550
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:30 amGYE - SFO
2 stops28h 15mUnited Airlines
Thu 11/278:45 amSFO - GYE
1 stop32h 58mUnited Airlines
Deal found 11/3$555
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:10 amGYE - SFO
2 stops17h 17mAmerican Airlines
Wed 1/2111:13 pmSFO - GYE
2 stops21h 09mAmerican Airlines
Deal found 11/4$568
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:08 amGYE - SFO
1 stop20h 51mAmerican Airlines
Tue 1/61:15 pmSFO - GYE
1 stop31h 07mAmerican Airlines
Deal found 11/4$571

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.

Fly from

Guayaquil

Fly to

San Francisco

Route

Depart

Return

Price

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 12/12

4:30 pm-10:35 am

1 stop21h 05m

San Francisco

Wed 1/21

2:25 pm-7:20 am

1 stop13h 55m

$445

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sun 2/1

4:30 pm-12:50 pm

1 stop23h 20m

San Francisco

Wed 2/18

12:10 pm-7:20 am

1 stop16h 10m

$469

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 12/19

7:30 am-7:30 pm

1 stop15h 00m

San Francisco

Fri 12/26

11:54 pm-3:10 pm

1 stop12h 16m

$502

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sun 2/1

4:45 pm-10:31 am

1 stop20h 46m

San Francisco

Wed 2/18

10:39 pm-2:20 pm

1 stop12h 41m

$517

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

4:40 am-9:50 pm

2 stops20h 10m

San Francisco

Tue 12/2

1:35 am-11:35 pm

2 stops19h 00m

$534

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 12/12

12:20 pm-11:17 pm

1 stop13h 57m

San Francisco

Tue 1/20

12:42 am-1:34 pm

1 stop9h 52m

$549

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

9:05 am-9:50 pm

2 stops15h 45m

San Francisco

Sat 2/28

1:20 pm-10:20 am

2 stops18h 00m

$550

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

8:34 am-7:49 am

2 stops26h 15m

San Francisco

Fri 2/27

12:43 am-11:42 pm

2 stops19h 59m

$555

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

7:20 am-10:49 pm

1 stop18h 29m

San Francisco

Sat 2/28

10:39 pm-2:20 pm

1 stop12h 41m

$569

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

10:25 am-9:50 pm

2 stops14h 25m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 16 results
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2

Compare providers for flights from Guayaquil to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to San Francisco in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Guayaquil-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Guayaquil-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Guayaquil-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guayaquil-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guayaquil to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to San Francisco

How far ahead should I book a flight from Guayaquil to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to San Francisco. Price data was last updated on October 31, 2025.

To ensure you get the cheapest price possible for a flight from Guayaquil to San Francisco, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Guayaquil to San Francisco?

Currently, June is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $258). Flying from Guayaquil to San Francisco in August is currently the most expensive (average of $524). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to SFO?

Find hourly flight availability from Guayaquil to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

A simple way to save on the total cost of your ticket is to fly from Guayaquil to San Francisco at noon. If you’re flexible enough to do this you can expect to save up to 9% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated November 5, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, United Airlines, and Avianca from Guayaquil to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,561 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
9,001 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,471 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Guayaquil to San Francisco?

    Delta, JetBlue, and Avianca can get you from Guayaquil to San Francisco in just under 15h. Your travel time can differ by up to 6h 05m. Guayaquil and San Francisco are separated by a distance of 3860 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Guayaquil to San Francisco round-trip?

    Our cheapest airline available from Guayaquil to San Francisco is Copa Airlines. Our recent data shows that you can find tickets from as low as $295 on this airline. Additional options worth looking into are United Airlines and Avianca, starting at $301 and $398 round-trip. Copa Airlines is currently priced 50% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Guayaquil to San Francisco one-way?

    $262 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on JetBlue and Copa Airlines, with prices starting from $285 and $302, respectively.

  • Can I find deals for flights from Guayaquil to San Francisco that include hotel bookings?

    Yes. In addition to deals on Guayaquil to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to San Francisco.

  • Can I find deals for business class flights from Guayaquil to San Francisco?

    Yes. Cheapflights offers flight deals from Guayaquil to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to San Francisco?

    Currently, June is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $258). Flying from Guayaquil to San Francisco in August is currently the most expensive (average of $524). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
Vallejo
Hollister
San Bruno
Foster City
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Burlingame
Lodi
San Mateo
Vacaville
Lathrop

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Guayaquil to San Francisco

Discover the top 3 airlines that operate flights from Guayaquil to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$295Average$809FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$301Average$601FlexibilityNo cancel feeOn-time69%
AviancaCheapest$398Average$609FlexibilityNo cancel feeOn-time71%

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