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$299+ Cheap flights from Guayaquil (GYE) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SFO
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to San Francisco are usually found in November or June, booked 67 days in advance, depart on a Monday or Tuesday and return on a Sunday

Cheap flight deals from Guayaquil to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$516
(SmartFares)

One-way from

$299
(Cheapflightsfares)

Popular in

August

Cheapest in

November

Average price

$573
From Guayaquil Jose Joaquin de Olmedo to San Francisco
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One-way flight from Guayaquil Jose Joaquin de Olmedo to San Francisco
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Highest demand for flights based on searches. 6% potential increase in price ($41 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Guayaquil to San Francisco

Cheapest flights from Guayaquil to San Francisco
Explore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This SmartFares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:40 pmGYE - SFO
1 stop34h 36mJetBlue
Wed 10/2211:20 pmSFO - GYE
1 stop12h 10mJetBlue
Deal found 9/13$516
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/63:15 amGYE - SFO
1 stop11h 20mAvianca
Wed 10/1512:05 amSFO - GYE
2 stops15h 15mAvianca
Deal found 9/14$544
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/78:30 amGYE - SFO
1 stop14h 40mUnited Airlines
Thu 10/1610:55 amSFO - GYE
1 stop24h 51mUnited Airlines
Deal found 9/14$549
This Priceline deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/143:35 amGYE - SFO
2 stops21h 10mAvianca
Thu 10/302:35 amSFO - GYE
2 stops20h 30mAvianca
Deal found 9/13$550
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/193:35 amGYE - SFO
2 stops21h 10mAvianca
Sat 9/2712:05 amSFO - GYE
2 stops20h 35mAvianca
Deal found 9/13$554
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2712:17 pmGYE - SFO
2 stops26h 02mUnited Airlines
Thu 10/210:55 amSFO - GYE
1 stop22h 20mUnited Airlines
Deal found 9/14$555
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/123:35 amGYE - SFO
2 stops21h 10mAvianca
Thu 10/162:30 amSFO - GYE
1 stop21h 35mAvianca
Deal found 9/13$561
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/108:30 amGYE - SFO
1 stop14h 40mUnited Airlines
Sun 10/1910:55 amSFO - GYE
1 stop24h 51mUnited Airlines
Deal found 9/13$573
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2512:21 pmGYE - SFO
1 stop11h 08mUnited Airlines
Mon 12/111:59 pmSFO - GYE
2 stops20h 42mUnited Airlines
Deal found 9/13$578

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.

Fly from

Guayaquil

Fly to

San Francisco

Route

Depart

Return

Price

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Thu 11/13

3:30 am-9:50 pm

2 stops21h 20m

San Francisco

Tue 11/25

1:35 am-11:35 pm

2 stops19h 00m

$544

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Tue 10/14

3:15 am-12:35 pm

1 stop11h 20m

San Francisco

Tue 10/21

12:05 am-5:20 pm

2 stops15h 15m

$544

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sun 10/12

3:35 am-10:45 pm

2 stops21h 10m

San Francisco

Thu 10/16

12:05 am-5:20 pm

2 stops15h 15m

$544

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 9/26

3:15 am-12:35 pm

1 stop11h 20m

San Francisco

Wed 10/1

12:05 am-5:20 pm

2 stops15h 15m

$544

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 10/3

12:15 pm-9:10 pm

1 stop10h 55m

San Francisco

Mon 10/6

10:55 am-11:15 am

1 stop22h 20m

$549

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Mon 10/13

8:30 am-9:10 pm

1 stop14h 40m

San Francisco

Fri 10/17

10:55 am-1:46 pm

1 stop24h 51m

$549

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 10/15

12:15 pm-9:10 pm

1 stop10h 55m

San Francisco

Tue 10/21

12:43 am-11:37 pm

2 stops20h 54m

$549

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 11/14

2:35 pm-8:29 pm

1 stop32h 54m

San Francisco

Wed 11/26

8:45 am-11:18 am

1 stop23h 33m

$549

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Tue 10/7

8:30 am-9:10 pm

1 stop14h 40m

San Francisco

Thu 10/16

10:55 am-11:37 pm

1 stop10h 42m

$549

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 11/12

10:25 am-9:50 pm

2 stops14h 25m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 12 results
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Best time to book a flight from Guayaquil to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to San Francisco

How far ahead should I book a flight from Guayaquil to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to San Francisco. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Guayaquil to San Francisco, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Guayaquil to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $276). Flying from Guayaquil to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to SFO?

Find hourly flight availability from Guayaquil to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Guayaquil to San Francisco at noon. If you’re flexible enough to do this you can expect to save up to 10% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, United Airlines, and Avianca from Guayaquil to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Overall

7.6

Boarding

7.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Overall

7.6

Boarding

7.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
8,931 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Overall

7.6

Boarding

7.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Overall

7.6

Boarding

7.8

Entertainment

6.8

Crew

8.1

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Guayaquil to San Francisco?

    Avianca can get you from Guayaquil to San Francisco in just under 21h 20m. Your travel time can differ by up to . Guayaquil and San Francisco are separated by a distance of 3860 mi.

  • What are the cheapest airlines flying from Guayaquil to San Francisco round-trip?

    Our cheapest airline available from Guayaquil to San Francisco is Avianca. Our recent data shows that you can find tickets from as low as $256 on this airline. Additional options worth looking into are Copa Airlines and United Airlines, starting at $297 and $301 round-trip. Avianca is currently priced 55% below the average price you’ll pay for this route.

  • Can I find deals for flights from Guayaquil to San Francisco that include hotel bookings?

    Yes. In addition to deals on Guayaquil to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to San Francisco.

  • Can I find deals for business class flights from Guayaquil to San Francisco?

    Yes. Cheapflights offers flight deals from Guayaquil to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $276). Flying from Guayaquil to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Manteca
Santa Clara
Sunnyvale
Hollister
Vacaville
Foster City
Vallejo
Burlingame
Redwood City
Union City
San Leandro
San Mateo
Lathrop

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Guayaquil to San Francisco

Discover the top 3 airlines that operate flights from Guayaquil to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$256Average$596FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$297Average$738FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$301Average$601FlexibilityNo cancel feeOn-time69%

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