$265+ Cheap flights from Guayaquil (GYE) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SFO
May 10 — May 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Guayaquil to San FranciscoExplore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:00 pm
GYE
- SFO
1 stop20h 54m
Delta
Tue 11/109:00 am
SFO
- GYE
1 stop19h 55m
Delta
Deal found 4/9![Delta logo]()
$523
This LATAM Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:05 pm
GYE
- SFO
1 stop24h 52m
LATAM Airlines
Mon 5/1111:35 am
SFO
- GYE
1 stop17h 25m
LATAM Airlines
Deal found 4/7![LATAM Airlines logo]()
$532
This oojo deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:05 pm
GYE
- SFO
1 stop19h 07m
Multiple Airlines
Sun 10/112:30 pm
SFO
- GYE
1 stop14h 30m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$538
This oojo deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:05 pm
GYE
- SFO
1 stop19h 05m
Multiple Airlines
Tue 9/2211:59 pm
SFO
- GYE
1 stop29h 01m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:05 pm
GYE
- SFO
2 stops30h 20m
Multiple Airlines
Tue 5/121:12 am
SFO
- GYE
1 stop10h 21m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:05 am
GYE
- SFO
1 stop19h 54m
American Airlines
Wed 5/2711:58 pm
SFO
- GYE
1 stop11h 33m
American Airlines
Deal found 4/7![American Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:05 am
GYE
- SFO
1 stop18h 56m
American Airlines
Mon 5/258:13 pm
SFO
- GYE
2 stops15h 18m
American Airlines
Deal found 4/7![American Airlines logo]()
$561
This Avianca deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:05 am
GYE
- SFO
2 stops14h 30m
Avianca
Sat 5/302:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Deal found 4/6![Avianca logo]()
$566
This Avianca deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:05 am
GYE
- SFO
2 stops14h 30m
Avianca
Fri 10/302:20 pm
SFO
- GYE
2 stops16h 45m
Avianca
Deal found 4/6![Avianca logo]()
$567
This Avianca deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:10 am
GYE
- SFO
2 stops15h 25m
Avianca
Sat 5/302:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Deal found 4/8![Avianca logo]()
$568
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:31 pm
GYE
- SFO
2 stops20h 03m
American Airlines
Sun 9/2711:58 pm
SFO
- GYE
2 stops17h 02m
American Airlines
Deal found 4/7![American Airlines logo]()
$570
Best flights from Guayaquil to San FranciscoDiscover carefully curated flight deals from Guayaquil to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Guayaquil to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:37 pm
GYE
- SFO
1 stop29h 33m
Copa Airlines
Mon 9/211:12 am
SFO
- GYE
1 stop20h 49m
Copa Airlines
Deal found 4/5![Copa Airlines logo]()
$566
This Avianca deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:05 am
GYE
- SFO
2 stops14h 30m
Avianca
Mon 5/252:15 pm
SFO
- GYE
2 stops16h 55m
Avianca
Deal found 4/5![Avianca logo]()
$566
This Faresmojo deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:25 pm
GYE
- SFO
1 stop13h 31m
JetBlue
Sun 5/32:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Deal found 4/5![JetBlue logo]()
$582
This Expedia deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:15 pm
GYE
- SFO
1 stop13h 18m
Multiple Airlines
Sat 5/302:15 pm
SFO
- GYE
2 stops16h 40m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$618
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:22 pm
GYE
- SFO
2 stops13h 37m
United Airlines
Mon 5/1111:59 pm
SFO
- GYE
2 stops21h 37m
United Airlines
Deal found 4/5![United Airlines logo]()
$619
This Avianca deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:05 am
GYE
- SFO
2 stops14h 30m
Avianca
Sat 5/3011:55 pm
SFO
- GYE
2 stops15h 40m
Avianca
Deal found 4/5![Avianca logo]()
$566
This Copa Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:43 pm
GYE
- SFO
1 stop10h 57m
Copa Airlines
Thu 5/288:16 pm
SFO
- GYE
1 stop15h 17m
Copa Airlines
Deal found 4/5![Copa Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:21 pm
GYE
- SFO
2 stops13h 54m
United Airlines
Sat 6/136:54 pm
SFO
- GYE
2 stops23h 57m
United Airlines
Deal found 4/9![United Airlines logo]()
$634
This oojo deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:50 pm
GYE
- SFO
2 stops29h 45m
Avianca
Sun 5/312:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Deal found 4/9![Avianca logo]()
$635
Last-minute flights from Guayaquil to San FranciscoDiscover last-minute flight deals from Guayaquil to San Francisco. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to San Francisco. Data last updated April 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:05 pm
GYE
- SFO
2 stops30h 20m
Multiple Airlines
Tue 5/121:12 am
SFO
- GYE
1 stop10h 21m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$551
This SmartFares deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:25 pm
GYE
- SFO
1 stop13h 31m
JetBlue
Tue 5/52:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Deal found 4/9![JetBlue logo]()
$579
This Faresmojo deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:25 pm
GYE
- SFO
1 stop13h 31m
JetBlue
Sun 5/32:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Deal found 4/5![JetBlue logo]()
$582
This LATAM Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:05 pm
GYE
- SFO
1 stop24h 52m
LATAM Airlines
Mon 5/1111:35 am
SFO
- GYE
1 stop17h 25m
LATAM Airlines
Deal found 4/7![LATAM Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:05 am
GYE
- SFO
1 stop19h 54m
American Airlines
Wed 5/2711:58 pm
SFO
- GYE
1 stop11h 33m
American Airlines
Deal found 4/7![American Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:05 am
GYE
- SFO
2 stops18h 59m
American Airlines
Sat 5/161:12 pm
SFO
- GYE
1 stop22h 19m
American Airlines
Deal found 4/6![American Airlines logo]()
$573
This Faresmojo deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/103:51 pm
GYE
- SFO
1 stop19h 34m
JetBlue
Sat 5/163:44 pm
SFO
- GYE
1 stop17h 14m
JetBlue
Deal found 4/7![JetBlue logo]()
$587
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:05 am
GYE
- SFO
1 stop18h 56m
American Airlines
Mon 5/258:13 pm
SFO
- GYE
2 stops15h 18m
American Airlines
Deal found 4/7![American Airlines logo]()
$561
This Avianca deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:05 am
GYE
- SFO
2 stops14h 30m
Avianca
Sat 5/302:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Deal found 4/6![Avianca logo]()
$566
This Avianca deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:10 am
GYE
- SFO
2 stops15h 25m
Avianca
Sat 5/302:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Deal found 4/8![Avianca logo]()
$568
One-way flights from Guayaquil to San FranciscoSearch for one-way flight options from Guayaquil to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Guayaquil to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:50 pm
GYE
- SFO
3 stops54h 14m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$265
This SmartFares deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:25 pm
GYE
- SFO
1 stop13h 31m
JetBlue
Deal found 4/6![JetBlue logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:59 pm
GYE
- SFO
3 stops50h 24m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$280
This SmartFares deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:30 pm
GYE
- SFO
1 stop13h 21m
JetBlue
Deal found 4/9![JetBlue logo]()
$282
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:05 pm
GYE
- SFO
1 stop20h 35m
Delta
Deal found 4/10![Delta logo]()
$292
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:05 pm
GYE
- SFO
1 stop25h 12m
Delta
Deal found 4/10![Delta logo]()
$293
This LATAM Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:05 pm
GYE
- SFO
1 stop20h 35m
LATAM Airlines
Deal found 4/10![LATAM Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:05 pm
GYE
- SFO
2 stops26h 29m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$302
This LATAM Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:05 pm
GYE
- SFO
1 stop20h 35m
LATAM Airlines
Deal found 4/8![LATAM Airlines logo]()
$309
This Copa Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:22 pm
GYE
- SFO
1 stop13h 18m
Copa Airlines
Deal found 4/9![Copa Airlines logo]()
$310
This Avianca deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:50 pm
GYE
- SFO
2 stops20h 00m
Avianca
Deal found 4/10![Avianca logo]()
$311
Find flight deals from Guayaquil to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $532 (LATAM Airlines) |
One-way from | $265 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $622 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Tue 9/8
2:37 pm-6:10 pm
1 stop29h 33m
San Francisco
Mon 9/21
1:12 am-12:01 am
1 stop20h 49m
$566
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Wed 5/20
10:05 am-10:35 pm
2 stops14h 30m
San Francisco
Mon 5/25
2:15 pm-9:10 am
2 stops16h 55m
$566
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Fri 5/22
10:05 am-10:35 pm
2 stops14h 30m
San Francisco
Sat 5/30
11:55 pm-5:35 pm
2 stops15h 40m
$566
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Thu 4/30
12:25 pm-11:56 pm
1 stop13h 31m
San Francisco
Sun 5/3
2:45 pm-10:58 am
1 stop18h 13m
$582
Quickest round-trip
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Thu 5/21
2:43 pm-11:40 pm
1 stop10h 57m
San Francisco
Thu 5/28
8:16 pm-1:33 pm
1 stop15h 17m
$594
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Sat 5/23
1:15 pm-12:33 am
1 stop13h 18m
San Francisco
Sat 5/30
2:15 pm-8:55 am
2 stops16h 40m
$618
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Fri 5/8
12:22 pm-11:59 pm
2 stops13h 37m
San Francisco
Mon 5/11
11:59 pm-11:36 pm
2 stops21h 37m
$619
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Thu 6/4
12:21 pm-12:15 am
2 stops13h 54m
San Francisco
Sat 6/13
6:54 pm-8:51 pm
2 stops23h 57m
$634
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Fri 5/1
6:50 pm-10:35 pm
2 stops29h 45m
San Francisco
Sun 5/31
2:15 pm-8:55 am
2 stops16h 40m
$635
Cheapest one-way
GuayaquilSan Francisco
GYE - SFO
GYESFO
Guayaquil Jose Joaquin de Olmedo
Wed 4/29
12:25 pm-11:56 pm
1 stop13h 31m
$270
Showing 1-10 of 21 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Guayaquil-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Guayaquil with our price prediction graph.
GYE-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to San Francisco
How far ahead should I book a flight from Guayaquil to San Francisco?
Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to San Francisco. Price data was last updated on April 3, 2026.
To ensure you get the cheapest price possible for a flight from Guayaquil to San Francisco, you should look to book at least 33 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Guayaquil to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $258). Flying from Guayaquil to San Francisco in August is currently the most expensive (average of $495). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Guayaquil to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 10, 2026.
Peruse reviews from past customers who have flown with Copa Airlines,United Airlines, andAvianca from Guayaquil to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Comfort
7.4
Entertainment
6.8
Overall
7.5
Boarding
7.7
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Crew
8.1
Comfort
7.4
Entertainment
6.8
Overall
7.5
Boarding
7.7
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Crew
8.1
Comfort
7.4
Entertainment
6.8
Overall
7.5
Boarding
7.7
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Crew
8.1
Comfort
7.4
Entertainment
6.8
Overall
7.5
Boarding
7.7
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Livermore
Roseville
Rancho Cordova
San Bruno
Watsonville
San Ramon
Union City
Emeryville
Vacaville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Elk Grove
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Guayaquil and San Francisco flights
Browse other Guayaquil and San Francisco flight options. Last updated on April 10, 2026.
Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
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Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
Top 3 airlines flying from Guayaquil to San Francisco
Discover the top 3 airlines that operate flights from Guayaquil to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$295 | Average$597 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$301 | Average$549 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$498 | Average$666 | FlexibilityNo cancel fee | On-time71% |