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$309+ Cheap flights from Guayaquil (GYE) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SFO
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from Guayaquil to San Francisco

Cheapest flights from Guayaquil to San Francisco
Explore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:00 pm
GYE
-
SFO
1 stop20h 54m
Delta
Tue 11/109:00 am
SFO
-
GYE
1 stop19h 55m
Delta
Deal found 4/18$523
This JetBlue deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:30 pm
GYE
-
SFO
1 stop13h 21m
JetBlue
Mon 5/1110:45 pm
SFO
-
GYE
1 stop13h 41m
JetBlue
Deal found 4/19$544
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
GYE
-
SFO
2 stops20h 09m
American Airlines
Tue 6/96:55 pm
SFO
-
GYE
2 stops16h 36m
American Airlines
Deal found 4/18$561
This BusinessClass deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/182:31 pm
GYE
-
SFO
2 stops23h 51m
GOL
Fri 5/2912:18 am
SFO
-
GYE
2 stops20h 19m
GOL
Deal found 4/22$563
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:31 pm
GYE
-
SFO
1 stop22h 23m
American Airlines
Sat 5/307:45 am
SFO
-
GYE
1 stop12h 52m
American Airlines
Deal found 4/21$565
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:29 am
GYE
-
SFO
1 stop21h 11m
Copa Airlines
Mon 9/211:12 am
SFO
-
GYE
1 stop14h 18m
Copa Airlines
Deal found 4/20$566
This Avianca deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:05 am
GYE
-
SFO
2 stops14h 30m
Avianca
Fri 10/302:20 pm
SFO
-
GYE
2 stops16h 45m
Avianca
Deal found 4/21$567
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
GYE
-
SFO
1 stop19h 59m
American Airlines
Sun 9/2711:58 pm
SFO
-
GYE
2 stops17h 02m
American Airlines
Deal found 4/23$582
This Avianca deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:05 am
GYE
-
SFO
2 stops15h 45m
Avianca
Mon 11/21:20 pm
SFO
-
GYE
2 stops18h 05m
Avianca
Deal found 4/20$587

Find flight deals from Guayaquil to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$544
(JetBlue)

One-way from

$309
(Cheapflightsfares)

Popular in

March

Cheapest in

November

Average price

$622
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-San Francisco flights.
Search Deals
From Guayaquil Jose Joaquin de Olmedo to San Francisco
Search Deals
One-way flight from Guayaquil Jose Joaquin de Olmedo to San Francisco
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Thu 5/7

12:30 pm-11:51 pm

1 stop13h 21m

San Francisco

Mon 5/11

10:45 pm-2:26 pm

1 stop13h 41m

$544

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 5/22

8:28 am-11:40 pm

1 stop17h 12m

San Francisco

Sat 5/30

8:16 pm-1:33 pm

1 stop15h 17m

$566

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 5/20

10:05 am-10:35 pm

2 stops14h 30m

San Francisco

Mon 5/25

11:55 pm-5:35 pm

2 stops15h 40m

$566

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 6/6

4:28 am-6:14 pm

1 stop15h 46m

San Francisco

Sun 9/20

8:21 pm-5:30 pm

1 stop19h 09m

$594

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 6/5

8:27 am-6:14 pm

1 stop11h 47m

San Francisco

Sun 9/20

8:21 pm-5:30 pm

1 stop19h 09m

$594
Cheapest one-way
Quickest one-way

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Mon 5/4

10:05 am-10:35 pm

2 stops14h 30m

$309

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Tue 6/2

6:27 pm-4:41 pm

3 stops48h 14m

$330

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sun 7/19

10:05 am-10:35 pm

2 stops38h 30m

$333

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sun 7/19

6:50 pm-7:56 pm

3 stops51h 06m

$376

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Mon 5/4

12:25 pm-11:09 am

1 stop24h 44m

$418

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Showing 1-10 of 11 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Guayaquil-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guayaquil-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guayaquil to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to San Francisco

How far ahead should I book a flight from Guayaquil to San Francisco?

To ensure you get the cheapest price possible for a flight from Guayaquil to San Francisco, you should look to book at least 32 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Guayaquil to San Francisco?

Currently, November is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $382). Flying from Guayaquil to San Francisco in March is currently the most expensive (average of $697). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Guayaquil to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 23, 2026.
Peruse reviews from past customers who have flown with Copa Airlines,United Airlines, andAvianca from Guayaquil to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,578 reviews

Overall

7.5

Comfort

7.4

Boarding

7.8

Food

6.8

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Copa Airlines
7.5
Good
1,578 reviews
Copa Airlines
7.5
Good
1,578 reviews

Overall

7.5

Comfort

7.4

Boarding

7.8

Food

6.8

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
United Airlines
7.4
Good
9,635 reviews
Copa Airlines
7.5
Good
1,578 reviews

Overall

7.5

Comfort

7.4

Boarding

7.8

Food

6.8

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Avianca
6.5
Okay
2,515 reviews
Copa Airlines
7.5
Good
1,578 reviews

Overall

7.5

Comfort

7.4

Boarding

7.8

Food

6.8

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Guayaquil to San Francisco?

    JetBlue, Copa Airlines, and Avianca can get you from Guayaquil to San Francisco in just under 13h 21m. Your travel time can differ by up to 3h 51m. Guayaquil and San Francisco are separated by a distance of 3860 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Guayaquil to San Francisco round-trip?

    Our cheapest airline available from Guayaquil to San Francisco is Copa Airlines. Our recent data shows that you can find tickets from as low as $295 on this airline. Additional options worth looking into are United Airlines and Avianca, starting at $301 and $498 round-trip. Copa Airlines is currently priced 46% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Guayaquil to San Francisco one-way?

    $262 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on Avianca and JetBlue, with prices starting from $272 and $297, respectively.

  • Can I find deals for flights from Guayaquil to San Francisco that include hotel bookings?

    Yes. In addition to deals on Guayaquil to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to San Francisco.

  • Can I find deals for business class flights from Guayaquil to San Francisco?

    Yes. Cheapflights offers flight deals from Guayaquil to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to San Francisco?

    Currently, November is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $382). Flying from Guayaquil to San Francisco in March is currently the most expensive (average of $697). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Rancho Cordova
San Bruno
Watsonville
San Ramon
Union City
Emeryville
Newark
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Elk Grove

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Alternative routes for Guayaquil to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Guayaquil to San Francisco

Discover the top 3 airlines that operate flights from Guayaquil to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$295Average$597FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$301Average$314FlexibilityNo cancel feeOn-time69%
AviancaCheapest$498Average$672FlexibilityNo cancel feeOn-time71%

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