$313+ Cheap flights from Guayaquil (GYE) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SFO
Sep 20 — Sep 271
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Guayaquil to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guayaquil to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Guayaquil to San FranciscoExplore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Guayaquil to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:30 pm -
1 stop12h 47m
Fri 10/911:10 pm -
1 stop14h 12m
Deal found 8/17![JetBlue logo]()
$532
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:30 pm -
1 stop12h 49m
Tue 10/1311:10 pm -
1 stop14h 12m
Deal found 8/18![JetBlue logo]()
$561
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
1 stop17h 59m
Sat 10/248:33 am -
1 stop12h 06m
Deal found 8/18![American Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:29 pm -
1 stop22h 00m
Sat 11/149:35 pm -
1 stop22h 41m
Deal found 8/19![American Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:00 am -
2 stops20h 08m
Tue 1/1910:59 pm -
1 stop12h 28m
Deal found 8/21![American Airlines logo]()
$584
Best flights from Guayaquil to San FranciscoDiscover carefully curated flight deals from Guayaquil to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Guayaquil to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:29 pm -
2 stops20h 32m
Sat 11/149:35 pm -
1 stop22h 41m
Deal found 8/21![American Airlines logo]()
$584
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:18 pm -
1 stop13h 22m
Thu 11/57:36 pm -
1 stop12h 42m
Deal found 8/21![Copa Airlines logo]()
$652
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:19 pm -
1 stop22h 43m
Fri 10/302:35 pm -
1 stop14h 46m
Deal found 8/18![Delta logo]()
$667
This JetBlue deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:30 pm -
1 stop12h 37m
Mon 10/1911:10 pm -
1 stop14h 12m
Deal found 8/18![JetBlue logo]()
$668
This Avianca deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:05 am -
2 stops15h 50m
Mon 10/192:15 pm -
2 stops16h 40m
Deal found 8/21![Avianca logo]()
$715
This Copa Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:25 am -
1 stop17h 52m
Wed 12/307:36 pm -
1 stop25h 07m
Deal found 8/18![Copa Airlines logo]()
$682
This JetBlue deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:30 pm -
1 stop12h 37m
Mon 10/264:25 pm -
1 stop16h 40m
Deal found 8/17![JetBlue logo]()
$694
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:33 pm -
1 stop11h 07m
Sun 10/118:21 pm -
1 stop19h 09m
Deal found 8/21![Copa Airlines logo]()
$698
This JetBlue deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:55 pm -
1 stop19h 35m
Wed 11/44:25 pm -
1 stop16h 40m
Deal found 8/20![JetBlue logo]()
$709
This Copa Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:28 pm -
1 stop25h 42m
Mon 9/211:12 am -
1 stop14h 18m
Deal found 8/18![Copa Airlines logo]()
$698
This JetBlue deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:55 pm -
1 stop19h 35m
Wed 11/44:25 pm -
1 stop16h 40m
Deal found 8/20![JetBlue logo]()
$709
Last-minute flights from Guayaquil to San FranciscoDiscover last-minute flight deals from Guayaquil to San Francisco. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to San Francisco. Data last updated August 21, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:50 pm -
2 stops31h 05m
Wed 9/1611:10 pm -
1 stop14h 04m
Deal found 8/18![Multiple Airlines logo]()
$703
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:05 am -
2 stops14h 30m
Fri 10/911:55 pm -
2 stops21h 35m
Deal found 8/19![Avianca logo]()
$677
This Travelocity deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:50 pm -
2 stops29h 45m
Sat 10/1011:10 pm -
1 stop14h 12m
Deal found 8/19![Multiple Airlines logo]()
$697
This Avianca deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:30 am -
2 stops21h 05m
Mon 10/1211:55 pm -
2 stops21h 35m
Deal found 8/19![Avianca logo]()
$715
This Avianca deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:30 am -
2 stops21h 05m
Tue 10/1311:55 pm -
2 stops16h 55m
Deal found 8/17![Avianca logo]()
$727
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:50 pm -
2 stops20h 00m
Mon 10/1211:55 pm -
2 stops15h 40m
Deal found 8/17![Avianca logo]()
$689
This Avianca deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:10 am -
2 stops16h 45m
Tue 9/2211:55 pm -
2 stops16h 55m
Deal found 8/19![Avianca logo]()
$629
This Avianca deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:05 am -
2 stops15h 50m
Mon 10/1211:55 pm -
2 stops15h 40m
Deal found 8/17![Avianca logo]()
$641
This Copa Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:28 pm -
1 stop25h 42m
Mon 9/211:12 am -
1 stop14h 18m
Deal found 8/18![Copa Airlines logo]()
$698
This Trip.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:45 pm -
2 stops23h 05m
Sat 10/311:55 pm -
2 stops31h 00m
Deal found 8/20![Avianca logo]()
$670
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops17h 52m
Sat 10/39:29 pm -
2 stops22h 41m
Deal found 8/17![American Airlines logo]()
$686
One-way flights from Guayaquil to San FranciscoSearch for one-way flight options from Guayaquil to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Guayaquil to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:29 pm -
1 stop22h 00m
Deal found 8/17![American Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/263:30 pm -
1 stop22h 37m
Deal found 8/19![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/173:30 pm -
1 stop22h 32m
Deal found 8/21![American Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:00 am -
3 stops41h 14m
Deal found 8/17![Multiple Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:29 pm -
2 stops22h 34m
Deal found 8/20![American Airlines logo]()
$330
This Avianca deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:10 am -
2 stops16h 45m
Deal found 8/19![Avianca logo]()
$342
This Avianca deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:05 am -
2 stops14h 30m
Deal found 8/17![Avianca logo]()
$348
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:19 pm -
2 stops23h 26m
Deal found 8/19![Delta logo]()
$364
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:30 am -
2 stops21h 05m
Deal found 8/19![Avianca logo]()
$372
Find flight deals from Guayaquil to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $532 (Expedia) |
One-way from | $313 (American Airlines) |
Popular in | July |
Cheapest in | January |
Average price | $583 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Thu 10/22
2:29 pm-9:01 am
2 stops20h 32m
San Francisco
Sat 11/14
9:35 pm-11:16 pm
1 stop22h 41m
$584
Quickest round-trip
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Fri 10/23
12:18 pm-11:40 pm
1 stop13h 22m
San Francisco
Thu 11/5
7:36 pm-11:18 am
1 stop12h 42m
$652
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Fri 10/16
4:19 pm-1:02 pm
1 stop22h 43m
San Francisco
Fri 10/30
2:35 pm-7:21 am
1 stop14h 46m
$667
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Thu 10/15
1:30 pm-12:07 am
1 stop12h 37m
San Francisco
Mon 10/19
11:10 pm-3:22 pm
1 stop14h 12m
$668
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Mon 12/21
8:25 am-11:17 pm
1 stop17h 52m
San Francisco
Wed 12/30
7:36 pm-11:43 pm
1 stop25h 07m
$682
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Fri 10/23
1:30 pm-12:07 am
1 stop12h 37m
San Francisco
Mon 10/26
4:25 pm-11:05 am
1 stop16h 40m
$694
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Sun 10/4
2:33 pm-11:40 pm
1 stop11h 07m
San Francisco
Sun 10/11
8:21 pm-5:30 pm
1 stop19h 09m
$698
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Tue 9/15
6:28 pm-6:10 pm
1 stop25h 42m
San Francisco
Mon 9/21
1:12 am-5:30 pm
1 stop14h 18m
$698
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Tue 11/3
4:55 pm-9:30 am
1 stop19h 35m
San Francisco
Wed 11/4
4:25 pm-12:05 pm
1 stop16h 40m
$709
GuayaquilSan Francisco
GYE Guayaquil Jose Joaquin de Olmedo - SFO San Francisco
GYESFO
Guayaquil Jose Joaquin de Olmedo
Mon 11/2
4:55 pm-9:30 am
1 stop19h 35m
San Francisco
Wed 11/4
4:25 pm-12:05 pm
1 stop16h 40m
$709
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to San Francisco in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Guayaquil-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Guayaquil with our price prediction graph.
GYE-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to San Francisco
How far ahead should I book a flight from Guayaquil to San Francisco?
To ensure you get the cheapest price possible for a flight from Guayaquil to San Francisco, you should look to book at least 26 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Guayaquil to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Guayaquil to San Francisco (average of $432). Flying from Guayaquil to San Francisco in July is currently the most expensive (average of $743). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Guayaquil to San Francisco?
Airfare is below average for this route at the moment.
Guayaquil to San Francisco flights typically cost between $566 and $750 in October.The cheapest round-trip price found within the last 5 days was $532 on JetBlue (Oct 2-Oct 9).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 21, 2026.
Peruse reviews from past customers who have flown with Copa Airlines from Guayaquil to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Food
6.9
Comfort
7.4
Boarding
7.8
Overall
7.6
Crew
8.1
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Entertainment
6.8
Food
6.9
Comfort
7.4
Boarding
7.8
Overall
7.6
Crew
8.1
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Emeryville
Roseville
Burlingame
Rancho Cordova
Fairfield
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
Manteca
San Carlos
Turlock
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Guayaquil
Popular flights
San Francisco flight routes
Alternative routes for Guayaquil to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Guayaquil to San Francisco by cabin class
Find flights from Guayaquil to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Guayaquil and San Francisco flights
Browse other Guayaquil and San Francisco flight options. Last updated on August 21, 2026.
Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Top airline flying from Guayaquil to San Francisco
Discover the top airline that operate flights from Guayaquil to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$295 | Average$709 | FlexibilityNo cancel fee | On-time70% |