$443+ Cheap flights from Gainesville to San Francisco (GNV - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — SFO
Oct 20 — Oct 271
Round-trip
1 adult, Economy
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Find cheap flights from Gainesville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Gainesville to San Francisco
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One-way
Cheapest flights from Gainesville to San FranciscoExplore the most affordable flight options available from Gainesville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
Explore the most affordable flight options available from Gainesville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:10 am -
1 stop9h 15m
Sun 11/225:00 am -
1 stop9h 24m
Deal found 9/17![American Airlines logo]()
$565
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:18 pm -
1 stop9h 10m
Sat 9/2611:02 am -
1 stop9h 12m
Deal found 9/16![American Airlines logo]()
$575
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:03 pm -
1 stop7h 53m
Thu 10/2211:30 pm -
1 stop7h 04m
Deal found 9/15![Delta logo]()
$612
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:18 pm -
1 stop9h 31m
Tue 10/68:30 am -
1 stop10h 21m
Deal found 9/17![American Airlines logo]()
$616
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:03 pm -
1 stop7h 53m
Thu 10/2211:30 pm -
1 stop7h 04m
Deal found 9/16![Delta logo]()
$622
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:44 am -
1 stop9h 26m
Sat 9/2611:02 am -
1 stop9h 12m
Deal found 9/18![American Airlines logo]()
$644
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:19 am -
1 stop7h 23m
Mon 10/265:45 pm -
2 stops12h 49m
Deal found 9/18![Delta logo]()
$656
This deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:11 pm -
1 stop9h 35m
Sat 1/96:35 am -
1 stop7h 05m
Deal found 9/15![American Airlines logo]()
$658
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:11 pm -
1 stop8h 42m
Sun 1/35:30 am -
1 stop8h 11m
Deal found 9/17![American Airlines logo]()
$679
Best flights from Gainesville to San FranciscoDiscover carefully curated flight deals from Gainesville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
Discover carefully curated flight deals from Gainesville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:00 pm -
1 stop8h 39m
Sun 10/411:30 pm -
1 stop7h 01m
Deal found 9/15![Delta logo]()
$616
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:11 pm -
1 stop8h 42m
Sun 1/35:30 am -
1 stop8h 11m
Deal found 9/17![American Airlines logo]()
$679
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:03 pm -
1 stop7h 53m
Thu 10/2211:30 pm -
1 stop7h 04m
Deal found 9/16![Delta logo]()
$622
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
2 stops12h 01m
Sun 10/411:02 am -
1 stop9h 12m
Deal found 9/15![American Airlines logo]()
$680
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:06 pm -
1 stop7h 52m
Mon 11/2311:59 pm -
1 stop6h 32m
Deal found 9/15![Delta logo]()
$639
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:10 am -
1 stop9h 15m
Sun 11/227:12 pm -
2 stops10h 38m
Deal found 9/17![American Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:19 am -
1 stop7h 23m
Mon 10/265:45 pm -
2 stops12h 49m
Deal found 9/18![Delta logo]()
$656
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 pm -
1 stop9h 07m
Thu 10/2211:32 am -
2 stops9h 27m
Deal found 9/15![American Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:31 pm -
2 stops13h 00m
Mon 11/166:00 am -
1 stop9h 21m
Deal found 9/17![Delta logo]()
$656
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:53 am -
2 stops11h 09m
Tue 10/611:32 am -
2 stops9h 27m
Deal found 9/18![American Airlines logo]()
$779
Last-minute flights from Gainesville to San FranciscoDiscover last-minute flight deals from Gainesville to San Francisco. Data last updated September 20, 2026 and is based on user searches.
Discover last-minute flight deals from Gainesville to San Francisco. Data last updated September 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:44 am -
1 stop9h 26m
Sat 9/2611:02 am -
1 stop9h 12m
Deal found 9/18![American Airlines logo]()
$644
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:18 pm -
1 stop9h 31m
Tue 10/68:30 am -
1 stop10h 21m
Deal found 9/17![American Airlines logo]()
$616
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:03 pm -
1 stop7h 53m
Thu 10/2211:30 pm -
1 stop7h 04m
Deal found 9/15![Delta logo]()
$612
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 pm -
1 stop9h 07m
Thu 10/2211:32 am -
2 stops9h 27m
Deal found 9/15![American Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:03 pm -
1 stop7h 53m
Thu 10/2211:30 pm -
1 stop7h 04m
Deal found 9/16![Delta logo]()
$622
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:49 pm -
1 stop9h 35m
Mon 10/265:30 am -
1 stop8h 13m
Deal found 9/18![American Airlines logo]()
$565
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:19 am -
1 stop7h 23m
Mon 10/265:45 pm -
2 stops12h 49m
Deal found 9/18![Delta logo]()
$656
One-way flights from Gainesville to San FranciscoSearch for one-way flight options from Gainesville to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
Search for one-way flight options from Gainesville to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:55 am -
1 stop9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$443
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:07 am -
1 stop9h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$550
Find flight deals from Gainesville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $565 (American Airlines) |
One-way from | $443 (American Airlines) |
Popular in | December |
Cheapest in | May |
Average price | $591 |
Cheapflights Fare Finder
Customize your flight search to find flights from Gainesville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
Use the filters below to find and compare flights from Gainesville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Mon 10/26
5:13 pm-12:44 am
1 stop10h 31m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$443
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Wed 9/30
4:00 pm-9:39 pm
1 stop8h 39m
San Francisco
Sun 10/4
11:30 pm-9:31 am
1 stop7h 01m
$616
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Fri 10/16
7:03 pm-11:56 pm
1 stop7h 53m
San Francisco
Thu 10/22
11:30 pm-9:34 am
1 stop7h 04m
$622
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Sat 11/21
7:06 pm-11:58 pm
1 stop7h 52m
San Francisco
Mon 11/23
11:59 pm-9:31 am
1 stop6h 32m
$639
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Thu 10/22
10:19 am-2:42 pm
1 stop7h 23m
San Francisco
Mon 10/26
5:45 pm-9:34 am
2 stops12h 49m
$656
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Fri 11/13
1:31 pm-11:31 pm
2 stops13h 00m
San Francisco
Mon 11/16
6:00 am-6:21 pm
1 stop9h 21m
$656
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Fri 12/25
5:11 pm-10:53 pm
1 stop8h 42m
San Francisco
Sun 1/3
5:30 am-4:41 pm
1 stop8h 11m
$679
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Wed 9/30
6:00 am-3:01 pm
2 stops12h 01m
San Francisco
Sun 10/4
11:02 am-11:14 pm
1 stop9h 12m
$680
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Fri 11/20
6:10 am-12:25 pm
1 stop9h 15m
San Francisco
Sun 11/22
7:12 pm-8:50 am
2 stops10h 38m
$710
GainesvilleSan Francisco
GNV Gainesville Regional - SFO San Francisco
GNVSFO
Gainesville Regional
Thu 10/15
5:00 pm-11:07 pm
1 stop9h 07m
San Francisco
Thu 10/22
11:32 am-11:59 pm
2 stops9h 27m
$710
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Gainesville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to San Francisco in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Gainesville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Gainesville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Gainesville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Gainesville with our price prediction graph.
GNV-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Gainesville to San Francisco
What is the cheapest month to book a flight from Gainesville to San Francisco?
Currently, May is the cheapest month in which you can book a flight from Gainesville to San Francisco (average of $471). Flying from Gainesville to San Francisco in December is currently the most expensive (average of $739). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Gainesville to San Francisco?
Airfare is typical for this route at the moment.
Gainesville to San Francisco flights typically cost between $463 and $588 in November.The cheapest round-trip price found within the last 5 days was $565 on American Airlines (Nov 20-Nov 22).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 20, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Gainesville to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJames,Aug 2023
SEA - SFO
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJames,Aug 2023
SEA - SFO
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJames,Aug 2023
SEA - SFO
Related info for your journey
Find useful and relevant information for your journey from Gainesville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Emeryville
San Bruno
Burlingame
Rancho Cordova
Roseville
Fairfield
Hayward
Cupertino
Newark
San Ramon
Redwood City
Manteca
Vallejo
San Carlos
Turlock
Davis
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Gainesville and San Francisco flights
Browse other Gainesville and San Francisco flight options. Last updated on September 20, 2026.
Other flights from Gainesville
Browse through other flights departing from Gainesville. Flights are based on user searches made on Cheapflights and were last updated on September 20, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 20, 2026.
Top 2 airlines flying from Gainesville to San Francisco
Discover the top 2 airlines that operate flights from Gainesville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$388 | Average$546 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$428 | Average$591 | FlexibilityNo cancel fee | On-time71% |