HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Francisco

$288+ Cheap flights from Gainesville to San Francisco (GNV - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — SFO
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Gainesville to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Gainesville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$389
(Delta)

One-way from

$288
(Delta)

Popular in

October

Cheapest in

February

Average price

$738
Provider with most accurate pricing for Gainesville Regional-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-San Francisco flights.
Search Deals
From Gainesville Regional to San Francisco
Search Deals
One-way flight from Gainesville Regional to San Francisco
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Gainesville to San Francisco

Cheapest flights from Gainesville to San Francisco
Explore the most affordable flight options available from Gainesville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/64:10 pmGNV - SFO
1 stop8h 06mDelta
sáb. 12/1310:30 pmSFO - GNV
1 stop7h 55mDelta
Deal found 10/28$389
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/123:41 pmGNV - SFO
1 stop10h 39mDelta
sáb. 1/109:30 pmSFO - GNV
1 stop8h 56mDelta
Deal found 10/29$432
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/277:16 amGNV - SFO
1 stop9h 04mAmerican Airlines
mar. 12/211:59 pmSFO - GNV
1 stop9h 39mAmerican Airlines
Deal found 10/28$503
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/184:59 pmGNV - SFO
1 stop8h 09mAmerican Airlines
sáb. 11/2211:59 pmSFO - GNV
1 stop7h 51mAmerican Airlines
Deal found 10/30$505
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/253:46 pmGNV - SFO
1 stop10h 37mDelta
lun. 12/19:30 pmSFO - GNV
1 stop8h 55mDelta
Deal found 10/29$511
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/247:04 pmGNV - SFO
2 stops15h 26mDelta
lun. 12/19:30 pmSFO - GNV
1 stop8h 55mDelta
Deal found 10/29$522
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/124:10 pmGNV - SFO
1 stop10h 15mAmerican Airlines
sáb. 1/107:00 amSFO - GNV
2 stops13h 57mAmerican Airlines
Deal found 10/30$523
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/193:46 pmGNV - SFO
1 stop10h 37mDelta
mar. 11/259:30 pmSFO - GNV
1 stop8h 56mDelta
Deal found 10/29$526

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from Gainesville to San Francisco that are best for you.

Fly from

Gainesville

Fly to

San Francisco

Route

Depart

Return

Price

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

sáb. 12/6

4:10 pm-9:16 pm

1 stop8h 06m

San Francisco

sáb. 12/13

10:30 pm-9:25 am

1 stop7h 55m

$389

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

vie. 12/12

6:00 am-3:57 pm

2 stops12h 57m

San Francisco

sáb. 1/10

9:30 pm-9:26 am

1 stop8h 56m

$501

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

jue. 11/27

7:16 am-1:20 pm

1 stop9h 04m

San Francisco

mar. 12/2

11:59 pm-12:38 pm

1 stop9h 39m

$503

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

mar. 11/18

11:15 am-7:02 pm

2 stops10h 47m

San Francisco

sáb. 11/22

11:59 pm-10:50 am

1 stop7h 51m

$510

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

mar. 11/25

3:46 pm-11:23 pm

1 stop10h 37m

San Francisco

lun. 12/1

9:30 pm-9:25 am

1 stop8h 55m

$511

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

lun. 11/24

7:04 pm-7:30 am

2 stops15h 26m

San Francisco

lun. 12/1

9:30 pm-9:25 am

1 stop8h 55m

$522

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

vie. 12/12

4:10 pm-11:25 pm

1 stop10h 15m

San Francisco

sáb. 1/10

7:00 am-11:57 pm

2 stops13h 57m

$523

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

mié. 11/19

3:46 pm-11:23 pm

1 stop10h 37m

San Francisco

mar. 11/25

9:30 pm-9:26 am

1 stop8h 56m

$526

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

vie. 11/14

6:00 am-3:03 pm

2 stops12h 03m

San Francisco

sáb. 11/22

11:59 pm-10:50 am

1 stop7h 51m

$569

GainesvilleSan Francisco

GNV - SFO

GNVSFO

Gainesville Regional

dom. 12/7

7:04 pm-12:51 pm

2 stops20h 47m

$288

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 17 results
1
2

Compare providers for flights from Gainesville to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to San Francisco in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Gainesville-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Gainesville-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to San Francisco

What is the cheapest month to book a flight from Gainesville to San Francisco?

Currently, May is the cheapest month in which you can book a flight from Gainesville to San Francisco (average of $138). Flying from Gainesville to San Francisco in December is currently the most expensive (average of $194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to SFO?

Find hourly flight availability from Gainesville to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 41% on flights from Gainesville to San Francisco by exploring options for tickets in the afternoon.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated octubre 30, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Gainesville to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Gainesville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to San Francisco?

    There are many flights that can get you from Gainesville to San Francisco in 8h 06m. Fly via Delta or American Airlines to get the fastest option. The distance between Gainesville and San Francisco is about 2350 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Gainesville to San Francisco round-trip?

    Cheapflights users have booked flights from Gainesville to San Francisco round-trip from $269. Another airline that can offer you cheap pricing is American Airlines. You may be able to fly from Gainesville to San Francisco for 47% less than the average price by searching for these airlines.

  • Can I find deals for flights from Gainesville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Gainesville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to San Francisco.

  • Can I find deals for business class flights from Gainesville to San Francisco?

    Yes. Cheapflights offers flight deals from Gainesville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to San Francisco?

    Currently, May is the cheapest month in which you can book a flight from Gainesville to San Francisco (average of $138). Flying from Gainesville to San Francisco in December is currently the most expensive (average of $194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Watsonville
Sunnyvale
Santa Clara
Antioch
Manteca
Vallejo
Hollister
Vacaville
San Bruno
Foster City
Redwood City
Union City
Fairfield
Burlingame
Lodi

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Gainesville to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to Las Vegas flights
Orlando to Los Angeles flights
Fort Lauderdale to Las Vegas flights
Tampa to Las Vegas flights
Fort Lauderdale to Los Angeles flights
Miami to Los Angeles flights
Miami to Las Vegas flights
Tampa to Los Angeles flights
Miami to San Francisco flights
Tampa to San Francisco flights
Orlando to San Francisco flights
Tampa to San Diego flights
Miami to Ontario flights
Orlando to Ontario flights
Fort Lauderdale to San Francisco flights
Orlando to San Diego flights
Fort Lauderdale to Burbank flights
Jacksonville to Las Vegas flights
Fort Lauderdale to Santa Ana flights
Miami to San Diego flights
West Palm Beach to Las Vegas flights
West Palm Beach to Los Angeles flights
Orlando to Santa Ana flights
Fort Myers to Las Vegas flights
Fort Lauderdale to San Diego flights
Tampa to Ontario flights
Fort Lauderdale to Ontario flights
Pensacola to Las Vegas flights
Sarasota to Las Vegas flights
Jacksonville to Los Angeles flights
Miami to Santa Ana flights
Orlando to Burbank flights
Jacksonville to San Francisco flights
Orlando Sanford Intl to Las Vegas flights
Tampa to Santa Ana flights
Pensacola to Los Angeles flights
Tampa to Burbank flights
Orlando to Sacramento flights
Sarasota to Los Angeles flights
Panama City to Las Vegas flights
Sarasota to San Francisco flights
Fort Myers to Los Angeles flights
Tampa to San Jose flights
Valparaiso to Las Vegas flights
Orlando to San Jose flights
Tampa to Reno flights
West Palm Beach to San Diego flights
Jacksonville to Ontario flights
Jacksonville to San Diego flights
Miami to Reno flights

Top 2 airlines flying from Gainesville to San Francisco

Discover the top 2 airlines that operate flights from Gainesville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$269Average$487FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$318Average$486FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.