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$402+ Cheap flights from Cusco (CUZ) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
CUZ — SFO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Find flight deals from Cuzco to San Francisco

One-way flights from Cuzco to San Francisco
Search for one-way flight options from Cuzco to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:45 amCUZ - SFO
2 stops19h 12mLATAM Airlines
Deal found 9/11$402
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2911:20 pmCUZ - SFO
3 stops48h 43mMultiple Airlines
Deal found 9/11$518
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:20 pmCUZ - SFO
2 stops27h 29mLATAM Airlines
Deal found 9/11$558
This SmartFares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:50 pmCUZ - SFO
2 stops15h 44mMultiple Airlines
Deal found 9/11$572
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2812:05 amCUZ - SFO
2 stops25h 50mLATAM Airlines
Deal found 9/11$787
This Orbitz deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:10 pmCUZ - SFO
2 stops45h 50mAvianca
Deal found 9/11$802

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cuzco to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Cusco to San Francisco that are best for you.

Fly from

Cuzco

Fly to

San Francisco

Route

Depart

Return

Price

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Thu 9/25

6:45 am-11:57 pm

2 stops19h 12m

$402

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Sat 11/29

11:20 pm-9:03 pm

3 stops48h 43m

$518

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Sun 12/28

11:20 pm-11:49 pm

2 stops27h 29m

$558

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Sun 12/28

9:50 pm-10:34 am

2 stops15h 44m

$572

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Mon 1/5

10:00 pm-11:10 pm

3 stops28h 10m

$678

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Fri 11/28

12:05 am-10:55 pm

2 stops25h 50m

$787

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Cuzco to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Cuzco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Cuzco to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Cuzco to San Francisco that include hotel bookings?

    Yes. In addition to deals on Cuzco to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cuzco to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cuzco to San Francisco.

  • Can I find deals for business class flights from Cuzco to San Francisco?

    Yes. Cheapflights offers flight deals from Cuzco to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cusco to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Cusco to San Francisco (average of $276). Flying from Cusco to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
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Turlock
Antioch
Watsonville
Manteca
Santa Clara
Sunnyvale
Hollister
Vacaville
Foster City
Vallejo
Burlingame
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San Leandro
San Mateo
Lathrop

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