$346+ Cheap flights from Cusco (CUZ) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
CUZ — SFO
Apr 11 — Apr 181
Round-trip
1 adult, Economy
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Find cheap flights from Cuzco to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Cuzco to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Cuzco to San FranciscoExplore the most affordable flight options available from Cuzco to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
Explore the most affordable flight options available from Cuzco to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:15 pm
CUZ
- SFO
2 stops21h 06m
LATAM Airlines
Mon 4/272:00 pm
SFO
- CUZ
2 stops16h 25m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$718
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:15 pm
CUZ
- SFO
3 stops31h 00m
LATAM Airlines
Sat 9/1211:05 am
SFO
- CUZ
2 stops41h 05m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$858
This Mytrip deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:00 am
CUZ
- SFO
3 stops31h 50m
Multiple Airlines
Wed 4/2911:55 pm
SFO
- CUZ
2 stops33h 25m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$947
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/22:40 pm
CUZ
- SFO
2 stops34h 32m
Multiple Airlines
Sat 9/1211:19 pm
SFO
- CUZ
2 stops30h 31m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$958
This BusinessClass deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:40 am
CUZ
- SFO
3 stops34h 39m
Multiple Airlines
Thu 3/268:26 am
SFO
- CUZ
2 stops19h 49m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$1,263
Best flights from Cuzco to San FranciscoDiscover carefully curated flight deals from Cuzco to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
Discover carefully curated flight deals from Cuzco to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:50 am
CUZ
- SFO
2 stops18h 20m
LATAM Airlines
Wed 4/294:17 pm
SFO
- CUZ
2 stops21h 03m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$718
This Mytrip deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:00 am
CUZ
- SFO
3 stops31h 50m
Multiple Airlines
Wed 4/2911:55 pm
SFO
- CUZ
2 stops33h 25m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$947
This LATAM Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:15 pm
CUZ
- SFO
2 stops20h 06m
LATAM Airlines
Mon 4/276:20 pm
SFO
- CUZ
2 stops19h 00m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$718
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:15 pm
CUZ
- SFO
3 stops31h 00m
LATAM Airlines
Sat 9/1211:05 am
SFO
- CUZ
2 stops41h 05m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$858
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/22:40 pm
CUZ
- SFO
2 stops34h 32m
Multiple Airlines
Sat 9/1211:19 pm
SFO
- CUZ
2 stops30h 31m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$958
This BusinessClass deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:40 am
CUZ
- SFO
3 stops34h 39m
Multiple Airlines
Thu 3/268:26 am
SFO
- CUZ
2 stops19h 49m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$1,263
Last-minute flights from Cuzco to San FranciscoDiscover last-minute flight deals from Cuzco to San Francisco. Data last updated March 12, 2026 and is based on user searches.
Discover last-minute flight deals from Cuzco to San Francisco. Data last updated March 12, 2026 and is based on user searches.
This BusinessClass deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:40 am
CUZ
- SFO
3 stops34h 39m
Multiple Airlines
Thu 3/268:26 am
SFO
- CUZ
2 stops19h 49m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$1,263
This Mytrip deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:00 am
CUZ
- SFO
3 stops31h 50m
Multiple Airlines
Wed 4/2911:55 pm
SFO
- CUZ
2 stops33h 25m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$947
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:15 pm
CUZ
- SFO
2 stops21h 06m
LATAM Airlines
Mon 4/272:00 pm
SFO
- CUZ
2 stops16h 25m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$718
One-way flights from Cuzco to San FranciscoSearch for one-way flight options from Cuzco to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
Search for one-way flight options from Cuzco to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
This FlightHub deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:15 pm
CUZ
- SFO
2 stops16h 44m
LATAM Airlines
Deal found 3/11![LATAM Airlines logo]()
$346
This FlightHub deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:05 am
CUZ
- SFO
2 stops25h 07m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$359
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/39:15 pm
CUZ
- SFO
2 stops19h 56m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:50 am
CUZ
- SFO
2 stops30h 02m
Delta
Deal found 3/7![Delta logo]()
$366
This FlightHub deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:05 am
CUZ
- SFO
2 stops24h 44m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$370
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:25 am
CUZ
- SFO
2 stops16h 47m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:25 am
CUZ
- SFO
2 stops16h 47m
Delta
Deal found 3/10![Delta logo]()
$377
This FlightHub deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:20 pm
CUZ
- SFO
2 stops19h 47m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$378
This Travelocity deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:00 am
CUZ
- SFO
2 stops28h 25m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:35 am
CUZ
- SFO
2 stops16h 37m
Delta
Deal found 3/10![Delta logo]()
$385
Find flight deals from Cuzco to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Cuzco (CUZ) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 12, 2026.
Round-trip from | $718 (LATAM Airlines) |
|---|---|
One-way from | $346 (FlightHub) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cuzco to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Cusco to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Wed 4/22
6:50 am-11:10 pm
2 stops18h 20m
San Francisco
Wed 4/29
4:17 pm-3:20 pm
2 stops21h 03m
$718
Quickest round-trip
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Thu 4/23
9:15 pm-3:21 pm
2 stops20h 06m
San Francisco
Mon 4/27
6:20 pm-3:20 pm
2 stops19h 00m
$718
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Sun 8/2
7:15 pm-12:15 am
3 stops31h 00m
San Francisco
Sat 9/12
11:05 am-6:10 am
2 stops41h 05m
$858
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Wed 4/22
7:00 am-12:50 pm
3 stops31h 50m
San Francisco
Wed 4/29
11:55 pm-11:20 am
2 stops33h 25m
$947
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Sun 8/2
2:40 pm-11:12 pm
2 stops34h 32m
San Francisco
Sat 9/12
11:19 pm-7:50 am
2 stops30h 31m
$958
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Mon 3/23
10:40 am-7:19 pm
3 stops34h 39m
San Francisco
Thu 3/26
8:26 am-6:15 am
2 stops19h 49m
$1,263
Cheapest one-way
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Tue 3/17
7:50 pm-3:03 pm
2 stops21h 13m
$366
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Thu 5/28
12:05 am-10:49 pm
2 stops24h 44m
$370
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Sat 8/8
5:00 am-8:26 am
2 stops29h 26m
$373
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Wed 8/12
8:25 am-11:12 pm
2 stops16h 47m
$373
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Cuzco to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Cuzco with our price prediction graph.
CUZ-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Cuzco to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
San Bruno
Sunnyvale
Vacaville
Turlock
San Carlos
San Ramon
Redwood City
Daly City
Rancho Cordova
San Lorenzo
Davis
Hollister
Manteca
Union City
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