How long is the flight from Cusco to San Francisco?

A quick flight from Cusco to San Francisco can take about 18h 40m. LATAM Airlines provides one of the quickest options available for as low as $701. The distance between Cusco and San Francisco is about 4810 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What is the cheapest time of day to fly from CUZ to SFO?

When flying from Cusco to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Cuzco to San Francisco that include hotel bookings?

Yes. In addition to deals on Cuzco to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Cuzco to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cuzco to San Francisco.

Can I find deals for business class flights from Cuzco to San Francisco?

Yes. Cheapflights offers flight deals from Cuzco to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$356+ Flights from Cusco to San Francisco

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Best flights from Cuzco to San Francisco
Discover carefully curated flight deals from Cuzco to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 28, 2025.

Thu 4/237:35 amCUZ - SFO

2 stops18h 40mLATAM Airlines

Sun 4/2611:30 amSFO - CUZ

2 stops19h 45mLATAM Airlines

Deal found 10/25

$701

Thu 4/236:55 amCUZ - SFO

2 stops19h 20mDelta

Sun 4/266:00 amSFO - CUZ

2 stops25h 15mDelta

Deal found 10/26

$701

One-way flights from Cuzco to San Francisco
Search for one-way flight options from Cuzco to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 28, 2025.

Sat 1/3112:05 amCUZ - SFO

2 stops26h 11mLATAM Airlines

Deal found 10/26

$356

Sat 3/216:40 pmCUZ - SFO

2 stops20h 20mMultiple Airlines

Deal found 10/28

$395

Mon 12/18:57 pmCUZ - SFO

2 stops28h 53mMultiple Airlines

Deal found 10/26

$402

Sun 2/19:45 pmCUZ - SFO

3 stops43h 17mMultiple Airlines

Deal found 10/26

$412

Mon 12/11:15 pmCUZ - SFO

3 stops50h 21mLATAM Airlines

Deal found 10/26

$420

Mon 1/57:50 pmCUZ - SFO

2 stops18h 58mMultiple Airlines

Deal found 10/26

$598

Sat 3/216:50 amCUZ - SFO

3 stops29h 45mLATAM Airlines

Deal found 10/28

$633

Tue 1/611:20 pmCUZ - SFO

3 stops50h 09mMultiple Airlines

Deal found 10/28

$650

Cheap flight deals from Cuzco to San Francisco

Round-trip from	$701 (Delta)
One-way from	$356 (LATAM Airlines)

From Cusco Velazco Astete to San Francisco

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One-way flight from Cusco Velazco Astete to San Francisco

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Cusco to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Thu 4/23

7:35 am-12:15 am

2 stops18h 40m

San Francisco

Sun 4/26

11:30 am-9:15 am

2 stops19h 45m

$701

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Thu 4/23

6:55 am-12:15 am

2 stops19h 20m

San Francisco

Sun 4/26

6:00 am-9:15 am

2 stops25h 15m

$701

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Sat 1/31

12:05 am-11:16 pm

2 stops26h 11m

$356

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Sat 3/21

6:40 pm-1:00 pm

2 stops20h 20m

$395

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Mon 12/1

8:57 pm-10:50 pm

2 stops28h 53m

$402

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Sun 2/1

9:45 pm-2:02 pm

3 stops43h 17m

$412

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Mon 12/1

1:15 pm-12:36 pm

3 stops50h 21m

$420

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Mon 1/5

7:50 pm-11:48 am

2 stops18h 58m

$598

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Sat 3/21

6:50 am-10:35 am

3 stops29h 45m

$633

CuscoSan Francisco

CUZ - SFO

CUZSFO

Cusco Velazco Astete

Tue 1/6

11:20 pm-10:29 pm

3 stops50h 09m

$650

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Best time to book a flight from Cuzco to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Cuzco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Cusco to San Francisco?
A quick flight from Cusco to San Francisco can take about 18h 40m. LATAM Airlines provides one of the quickest options available for as low as $701. The distance between Cusco and San Francisco is about 4810 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Cuzco to San Francisco that include hotel bookings?
Yes. In addition to deals on Cuzco to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Cuzco to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cuzco to San Francisco.
Can I find deals for business class flights from Cuzco to San Francisco?
Yes. Cheapflights offers flight deals from Cuzco to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Turlock

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Santa Clara

Antioch

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Vallejo

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San Bruno

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$356+ Cheap flights from Cusco (CUZ) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Cuzco to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Cuzco to San Francisco

Best flights from Cuzco to San FranciscoDiscover carefully curated flight deals from Cuzco to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 28, 2025.

Discover carefully curated flight deals from Cuzco to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 28, 2025.

Cheap flight deals from Cuzco to San Francisco

Round-trip from

One-way from

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Use the filters below to find and compare flights from Cusco to San Francisco that are best for you.

Best time to book a flight from Cuzco to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Cuzco with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Cuzco to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Cusco to San Francisco?

Can I find deals for flights from Cuzco to San Francisco that include hotel bookings?

How can I find direct flights from Cuzco to San Francisco?

Can I find deals for business class flights from Cuzco to San Francisco?

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Best flights from Cuzco to San Francisco
Discover carefully curated flight deals from Cuzco to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 28, 2025.