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San Francisco Bay Area

$110+ Cheap flights from Knoxville (TYS) to San Francisco Bay Area

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SFO
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Knoxville to San Francisco Bay Area

Keep the following information in mind while searching for Knoxville to San Francisco Bay Area flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$188
(Kiwi.com)

One-way from

$110
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$408
From Knoxville McGhee Tyson to San Francisco Bay Area
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One-way flight from Knoxville McGhee Tyson to San Francisco Bay Area
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Highest demand for flights based on searches. 1% potential increase in price ($6 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to San Francisco Bay Area

Cheapest flights from Knoxville to San Francisco Bay Area
Explore the most affordable flight options available from Knoxville to San Francisco Bay Area. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/246:00 amTYS - SFO
1 stop16h 10mMultiple Airlines
lun. 10/276:34 amSFO - TYS
1 stop9h 58mMultiple Airlines
Deal found 9/10$188
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/237:00 amTYS - SFO
1 stop10h 24mMultiple Airlines
dom. 10/268:21 pmSFO - TYS
1 stop20h 11mMultiple Airlines
Deal found 9/10$197
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/238:17 pmTYS - SFO
1 stop6h 57mFrontier
lun. 10/276:34 amSFO - TYS
1 stop9h 58mFrontier
Deal found 9/11$199
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/208:17 pmTYS - SFO
1 stop6h 57mFrontier
lun. 10/276:34 amSFO - TYS
1 stop9h 58mFrontier
Deal found 9/11$205
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/248:17 pmTYS - SFO
1 stop6h 57mFrontier
lun. 10/276:34 amSFO - TYS
1 stop9h 58mFrontier
Deal found 9/11$210
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/137:17 pmTYS - SFO
1 stop7h 57mFrontier
sáb. 11/156:39 pmSFO - TYS
2 stops20h 43mFrontier
Deal found 9/10$214
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/238:17 pmTYS - SFO
1 stop6h 57mFrontier
dom. 10/2610:38 pmSFO - TYS
2 stops17h 54mFrontier
Deal found 9/11$229
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/208:17 pmTYS - SFO
1 stop6h 57mFrontier
dom. 10/2610:38 pmSFO - TYS
2 stops17h 54mFrontier
Deal found 9/11$235
This Frontier deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/248:17 pmTYS - SFO
1 stop6h 57mFrontier
dom. 10/2610:38 pmSFO - TYS
2 stops17h 54mFrontier
Deal found 9/11$240
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/256:00 amTYS - SJC
1 stop9h 20mAmerican Airlines
sáb. 11/11:18 pmSJC - TYS
1 stop8h 05mAmerican Airlines
Deal found 9/9$244
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/16:08 pmTYS - SJC
1 stop7h 42mDelta
mar. 10/710:25 pmSJC - TYS
1 stop7h 35mDelta
Deal found 9/11$277
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/134:27 pmTYS - SJC
1 stop7h 22mAmerican Airlines
sáb. 11/156:00 amSJC - TYS
1 stop8h 28mAmerican Airlines
Deal found 9/10$286

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Knoxville to San Francisco Bay Area that are best for you.

Fly from

Knoxville

Fly to

San Francisco Bay Area

Route

Depart

Return

Price

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

jue. 11/13

7:17 pm-12:14 am

1 stop7h 57m

San Francisco

sáb. 11/15

6:34 am-1:44 pm

1 stop28h 10m

$197

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

vie. 10/24

6:00 am-1:58 pm

2 stops10h 58m

San Francisco

lun. 10/27

6:34 am-7:32 pm

1 stop9h 58m

$225

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

sáb. 10/25

6:00 am-12:20 pm

1 stop9h 20m

San Jose

sáb. 11/1

1:18 pm-12:23 am

1 stop8h 05m

$244

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

jue. 10/2

7:00 am-8:15 am

1 stop28h 15m

San Francisco

dom. 10/5

6:29 am-4:18 pm

1 stop6h 49m

$275

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

mié. 10/22

5:44 am-9:58 am

1 stop7h 14m

San Francisco

sáb. 10/25

11:25 am-9:13 pm

1 stop6h 48m

$277

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

mar. 10/21

3:48 pm-10:34 pm

1 stop9h 46m

San Francisco

mar. 10/28

6:10 am-4:31 pm

1 stop7h 21m

$277

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

mié. 10/22

6:40 am-10:53 am

1 stop7h 13m

San Francisco

mar. 10/28

9:50 pm-9:00 am

1 stop8h 10m

$277

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

mié. 10/1

6:08 pm-10:50 pm

1 stop7h 42m

San Jose

mar. 10/7

10:25 pm-9:00 am

1 stop7h 35m

$277

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

mar. 10/21

2:27 pm-7:59 pm

1 stop8h 32m

San Jose

mar. 10/28

12:40 pm-11:07 pm

1 stop7h 27m

$277

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

sáb. 2/7

11:07 am-3:35 pm

1 stop7h 28m

San Francisco

vie. 2/13

9:30 pm-9:45 am

1 stop9h 15m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 51 results
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Best time to book a flight from Knoxville to San Francisco Bay Area

Have a flexible travel schedule? Discover the best time to fly to San Francisco Bay Area from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to San Francisco Bay Area

What is the cheapest month to book a flight from Knoxville to San Francisco Bay Area?

Currently, January is the cheapest month in which you can book a flight from Knoxville to San Francisco Bay Area (average of $276). Flying from Knoxville to San Francisco Bay Area in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to XIH?

Find hourly flight availability from Knoxville to San Francisco Bay Area. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to San Francisco Bay Area as you normally would.

Reviews of airlines servicing San Francisco Bay Area

Get insights into the airlines that provide service to San Francisco Bay Area. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco Bay Area. Reviews last updated septiembre 11, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Knoxville to San Francisco Bay Area by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
5.8
Fair
3,177 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Francisco Bay Area. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to San Francisco Bay Area?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to San Francisco Bay Area from Knoxville.

  • How long is the flight from Knoxville to San Francisco Bay Area?

    A quick flight from Knoxville to San Francisco Bay Area can take about 7h 14m. American Airlines provides one of the quickest options available for as low as $277. There are 2114 mi between Knoxville and San Francisco Bay Area. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Knoxville to San Francisco Bay Area one-way?

    $122 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $122 and $139, respectively.

  • What are the most popular routes from Knoxville to San Francisco Bay Area?

    Most travelers choose Knoxville McGhee Tyson - San Jose, Knoxville McGhee Tyson - San Francisco or Knoxville McGhee Tyson - Oakland when deciding on the best route from Knoxville to San Francisco Bay Area.

  • Can I find deals for flights from Knoxville to San Francisco Bay Area that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Francisco Bay Area flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Francisco Bay Area?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Francisco Bay Area.

  • Can I find deals for business class flights from Knoxville to San Francisco Bay Area?

    Yes. Cheapflights offers flight deals from Knoxville to San Francisco Bay Area by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to San Francisco Bay Area?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to San Francisco Bay Area (average of $276). Flying from Knoxville to San Francisco Bay Area in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to San Francisco Bay Area

Discover the top 4 airlines that operate flights from Knoxville to San Francisco Bay Area. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$158Average$254FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$243Average$537FlexibilityNo cancel feeOn-time69%
DeltaCheapest$276Average$410FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$279Average$445FlexibilityNo cancel feeOn-time71%

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