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San Francisco Bay Area

$135+ Cheap flights from Knoxville (TYS) to San Francisco Bay Area

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SFO
May 10 — May 171
Sat 5/10
Sat 5/17
1 adult, Economy
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Cheap flight deals from Knoxville to San Francisco Bay Area

Keep the following information in mind while searching for Knoxville to San Francisco Bay Area flight deals. Data was last updated May 5, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$255
(American Airlines)

One-way from

$140
(Frontier)

Popular in

July

Cheapest in

January

Average price

$417
Provider with most accurate pricing for Knoxville McGhee Tyson-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-San Francisco flights.
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From Knoxville McGhee Tyson to San Francisco Bay Area
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One-way flight from Knoxville McGhee Tyson to San Francisco Bay Area
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Highest demand for flights based on searches. 16% potential increase in price ($89 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Knoxville to San Francisco Bay Area

Cheapest flights from Knoxville to San Francisco Bay Area
Explore the most affordable flight options available from Knoxville to San Francisco Bay Area. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2025.

This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/15:15 amTYS - SJC
1 stop8h 38mAmerican Airlines
Wed 7/97:09 pmSJC - TYS
2 stops12h 19mAmerican Airlines
Deal found 5/4$255
This Mytrip deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/910:59 amTYS - SFO
1 stop27h 09mMultiple Airlines
Thu 6/1211:59 pmSFO - TYS
1 stop13h 12mMultiple Airlines
Deal found 5/5$272
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/15:46 pmTYS - SJC
1 stop7h 49mUnited Airlines
Wed 7/91:05 pmSJC - TYS
1 stop7h 22mUnited Airlines
Deal found 5/4$277
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/225:30 pmTYS - SFO
1 stop9h 39mFrontier
Thu 5/296:35 amSFO - TYS
1 stop7h 00mFrontier
Deal found 5/5$280
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/106:42 amTYS - SJC
1 stop9h 01mDelta
Tue 6/174:59 pmSJC - TYS
2 stops14h 20mDelta
Deal found 5/4$282
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/105:00 pmTYS - SFO
1 stop8h 01mUnited Airlines
Tue 7/1511:25 pmSFO - TYS
1 stop7h 52mUnited Airlines
Deal found 5/4$309
This Mytrip deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/85:59 pmTYS - OAK
2 stops31h 26mMultiple Airlines
Wed 6/1111:51 amOAK - TYS
2 stops17h 28mMultiple Airlines
Deal found 5/5$320
This Mytrip deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/104:58 pmTYS - SJC
3 stops33h 31mMultiple Airlines
Tue 6/1711:01 amSJC - TYS
2 stops21h 49mMultiple Airlines
Deal found 5/4$325
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/236:28 pmTYS - SFO
1 stop7h 49mAmerican Airlines
Sun 5/2512:24 amSFO - TYS
1 stop8h 17mAmerican Airlines
Deal found 5/4$339
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1710:45 amTYS - SFO
1 stop10h 28mDelta
Sun 6/225:50 amSFO - TYS
1 stop8h 45mDelta
Deal found 5/5$364
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/165:30 amTYS - OAK
2 stops9h 15mDelta
Wed 7/304:58 pmOAK - TYS
2 stops14h 16mDelta
Deal found 5/3$557
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/216:00 amTYS - STS
2 stops12h 46mAmerican Airlines
Mon 8/2512:17 pmSTS - TYS
1 stop6h 28mAmerican Airlines
Deal found 5/5$672

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2025.
Use the filters below to find and compare flights from Knoxville to San Francisco Bay Area that are best for you.

Fly from

Knoxville

Fly to

San Francisco Bay Area

Route

Depart

Return

Price

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 7/1

5:15 am-10:53 am

1 stop8h 38m

San Jose

Wed 7/9

7:09 pm-10:28 am

2 stops12h 19m

$255

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 7/1

5:46 pm-10:35 pm

1 stop7h 49m

San Jose

Wed 7/9

1:05 pm-11:27 pm

1 stop7h 22m

$277

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 5/22

5:30 pm-12:09 am

1 stop9h 39m

San Francisco

Thu 5/29

6:35 am-4:35 pm

1 stop7h 00m

$280

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 6/10

6:42 am-12:43 pm

1 stop9h 01m

San Jose

Tue 6/17

4:59 pm-10:19 am

2 stops14h 20m

$282

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 8/14

5:30 am-10:17 am

1 stop7h 47m

San Francisco

Tue 8/19

7:30 am-6:17 pm

1 stop7h 47m

$309

KnoxvilleOakland

TYS - OAK

TYSOAK

Knoxville McGhee Tyson

Sun 6/8

5:59 pm-10:25 pm

2 stops31h 26m

Oakland

Wed 6/11

11:51 am-8:19 am

2 stops17h 28m

$320

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 6/10

4:58 pm-11:29 pm

3 stops33h 31m

San Jose

Tue 6/17

11:01 am-11:50 am

2 stops21h 49m

$325

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Fri 5/30

6:20 am-10:58 pm

1 stop19h 38m

San Francisco

Sun 6/8

11:59 pm-4:47 pm

2 stops13h 48m

$327

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Fri 5/23

6:28 pm-11:17 pm

1 stop7h 49m

San Francisco

Sun 5/25

12:24 am-11:41 am

1 stop8h 17m

$339

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Tue 9/16

12:00 pm-4:34 pm

1 stop7h 34m

San Francisco

Sun 9/21

11:59 pm-10:13 am

1 stop7h 14m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/5

Showing 1-10 of 24 results
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Best time to book a flight from Knoxville to San Francisco Bay Area

Have a flexible travel schedule? Discover the best time to fly to San Francisco Bay Area from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to San Francisco Bay Area

What is the cheapest month to book a flight from Knoxville to San Francisco Bay Area?

Currently, January is the cheapest month in which you can book a flight from Knoxville to San Francisco Bay Area (average of $276). Flying from Knoxville to San Francisco Bay Area in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to XIH?

Find hourly flight availability from Knoxville to San Francisco Bay Area. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 5, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to San Francisco Bay Area as you normally would.

Rainfall in San Francisco Bay Area by month

Plan your trip to San Francisco Bay Area by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco Bay Area ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco Bay Area when rainfall is around 0.0 in.

Temperature in San Francisco Bay Area by month

Plan your trip to San Francisco Bay Area by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco Bay Area, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco Bay Area

Get insights into the airlines that provide service to San Francisco Bay Area. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco Bay Area. Reviews last updated May 5, 2025.
Read reviews from past customers who have flown Alaska Airlines, Delta and United Airlines from Knoxville to San Francisco Bay Area. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,987 reviews

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,987 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,941 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,702 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Frontier
6.0
Okay
3,289 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Francisco Bay Area. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to San Francisco Bay Area?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to San Francisco Bay Area from Knoxville.

  • What are the cheapest airlines to fly from Knoxville to San Francisco Bay Area one-way?

    $140 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $170 and $205, respectively.

  • What are the most popular routes from Knoxville to San Francisco Bay Area?

    Most travelers choose Knoxville McGhee Tyson - San Francisco, Knoxville McGhee Tyson - San Jose or Knoxville McGhee Tyson - Oakland when deciding on the best route from Knoxville to San Francisco Bay Area.

  • Can I find deals for flights from Knoxville to San Francisco Bay Area that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Francisco Bay Area flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Francisco Bay Area?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Francisco Bay Area.

  • Can I find deals for business class flights from Knoxville to San Francisco Bay Area?

    Yes. Cheapflights offers flight deals from Knoxville to San Francisco Bay Area by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to San Francisco Bay Area?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to San Francisco Bay Area (average of $276). Flying from Knoxville to San Francisco Bay Area in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to San Francisco Bay Area

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Top 4 airlines flying from Knoxville to San Francisco Bay Area

Discover the top 4 airlines that operate flights from Knoxville to San Francisco Bay Area. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$155Average$190FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$248Average$529FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$281Average$448FlexibilityNo cancel feeOn-time71%
DeltaCheapest$287Average$474FlexibilityNo cancel feeOn-timeN/A

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