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$130+ Cheap flights from Key West (EYW) to San Francisco Bay Area

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SFO
Dec 23 — Dec 301
Tue 12/23
Tue 12/30
1 adult, Economy
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Find flight deals from Key West to San Francisco Bay Area

Cheapest flights from Key West to San Francisco Bay Area
Explore the most affordable flight options available from Key West to San Francisco Bay Area. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 23, 2025.

This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:02 pmEYW - SFO
1 stop11h 18mDelta
Sun 12/1410:30 pmSFO - EYW
1 stop10h 13mDelta
Deal found 11/20$259
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:39 pmEYW - SFO
1 stop9h 17mAmerican Airlines
Sat 12/1312:25 amSFO - EYW
1 stop8h 40mAmerican Airlines
Deal found 11/20$359
This Kiwi.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:55 amEYW - SFO
2 stops25h 58mMultiple Airlines
Thu 12/1112:50 pmSFO - EYW
1 stop20h 49mMultiple Airlines
Deal found 11/22$438
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:03 pmEYW - SFO
1 stop8h 36mAmerican Airlines
Tue 12/236:00 amSFO - EYW
1 stop7h 30mAmerican Airlines
Deal found 11/21$523
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:02 pmEYW - SJC
1 stop10h 53mDelta
Wed 12/246:35 amSJC - EYW
1 stop10h 08mDelta
Deal found 11/21$548
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/181:46 pmEYW - SJC
2 stops11h 52mAmerican Airlines
Tue 12/236:00 amSJC - EYW
1 stop7h 30mAmerican Airlines
Deal found 11/21$553
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:10 pmEYW - SJC
2 stops17h 14mDelta
Wed 12/246:35 amSJC - EYW
1 stop10h 08mDelta
Deal found 11/21$600
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:02 pmEYW - SJC
1 stop10h 53mDelta
Tue 12/2310:55 pmSJC - EYW
1 stop17h 48mDelta
Deal found 11/21$618
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:10 pmEYW - SJC
2 stops19h 46mDelta
Wed 12/246:35 amSJC - EYW
1 stop10h 08mDelta
Deal found 11/21$621
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:52 pmEYW - SJC
1 stop9h 21mAmerican Airlines
Tue 12/236:00 amSJC - EYW
1 stop7h 30mAmerican Airlines
Deal found 11/21$648
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:00 amEYW - SJC
2 stops9h 24mAmerican Airlines
Tue 12/236:00 amSJC - EYW
1 stop7h 30mAmerican Airlines
Deal found 11/21$653
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:28 pmEYW - SJC
1 stop9h 45mAmerican Airlines
Mon 12/229:56 amSJC - EYW
2 stops9h 48mAmerican Airlines
Deal found 11/21$657

Cheap flight deals from Key West to San Francisco Bay Area

Keep the following information in mind while searching for Key West to San Francisco Bay Area flight deals. Data was last updated November 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$259
(Delta)

One-way from

$130
(American Airlines)
Provider with most accurate pricing for Key West-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-San Francisco flights.
Search Deals
From Key West to San Francisco Bay Area
Search Deals
One-way flight from Key West to San Francisco Bay Area
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 23, 2025.
Use the filters below to find and compare flights from Key West to San Francisco Bay Area that are best for you.

Fly from

Key West

Fly to

San Francisco Bay Area

Route

Depart

Return

Price

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Fri 12/12

3:02 pm-11:20 pm

1 stop11h 18m

San Francisco

Sun 12/14

10:30 pm-11:43 am

1 stop10h 13m

$259

Key WestSan Jose

EYW - SJC

EYWSJC

Key West

Thu 1/8

2:45 pm-9:20 pm

1 stop9h 35m

San Jose

Sat 2/7

10:45 pm-11:25 am

1 stop9h 40m

$309

Key WestSan Jose

EYW - SJC

EYWSJC

Key West

Wed 1/7

7:10 am-12:56 pm

1 stop8h 46m

San Jose

Mon 1/19

10:45 pm-11:25 am

1 stop9h 40m

$309

Key WestSan Jose

EYW - SJC

EYWSJC

Key West

Fri 1/23

2:45 pm-9:20 pm

1 stop9h 35m

San Jose

Mon 1/26

10:45 pm-11:25 am

1 stop9h 40m

$309

Key WestSan Jose

EYW - SJC

EYWSJC

Key West

Wed 1/7

7:10 am-12:56 pm

1 stop8h 46m

San Jose

Tue 1/20

6:20 am-7:40 pm

2 stops10h 20m

$314

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Fri 12/12

2:39 pm-8:56 pm

1 stop9h 17m

San Francisco

Sat 12/13

12:25 am-12:05 pm

1 stop8h 40m

$359

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Tue 12/16

1:33 pm-9:02 pm

1 stop10h 29m

$130

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 1/7

1:05 pm-10:59 pm

1 stop12h 54m

$161

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 1/7

2:30 pm-8:03 am

3 stops44h 33m

$161

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Tue 12/30

12:20 pm-8:30 pm

3 stops59h 10m

$238

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/21

Showing 1-10 of 24 results
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Best time to book a flight from Key West to San Francisco Bay Area

Have a flexible travel schedule? Discover the best time to fly to San Francisco Bay Area from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to San Francisco Bay Area
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Francisco Bay Area

Get insights into the airlines that provide service to San Francisco Bay Area. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco Bay Area. Reviews last updated November 23, 2025.
Peruse reviews from past customers who have flown with American Airlines from Key West to San Francisco Bay Area to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,047 reviews

Food

6.4

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Overall

7.2

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,047 reviews
American Airlines
7.2
Good
11,047 reviews

Food

6.4

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Overall

7.2

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key West to San Francisco Bay Area. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Key West to San Francisco Bay Area?

    For a flight from Key West to San Francisco Bay Area, you will be flying from Key West. Key West (EYW) is just 2.6 mi from the center of the city.

  • How long is the flight from Key West to San Francisco Bay Area?

    There are many flights that can get you from Key West to San Francisco Bay Area in 11h 18m. Fly via Delta to get the fastest option. The distance between Key West and San Francisco Bay Area is about 2542 mi.

  • What are the cheapest airlines to fly from Key West to San Francisco Bay Area one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $130. JetBlue flights start at $161 while deals on Delta start at $525 one-way.

  • Can I find deals for flights from Key West to San Francisco Bay Area that include hotel bookings?

    Yes. In addition to deals on Key West to San Francisco Bay Area flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to San Francisco Bay Area?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to San Francisco Bay Area.

  • Can I find deals for business class flights from Key West to San Francisco Bay Area?

    Yes. Cheapflights offers flight deals from Key West to San Francisco Bay Area by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Key West to San Francisco Bay Area

Discover the top airline that operate flights from Key West to San Francisco Bay Area. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$313Average$453FlexibilityNo cancel feeOn-time71%

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