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$149+ Cheap flights from Biloxi, MS to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SAN
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Biloxi to San Diego

Keep the following information in mind while searching for Biloxi to San Diego flight deals. Data was last updated September 16, 2025.

Round-trip from

$289
(Delta)

One-way from

$149
(Delta)

Popular in

December

Cheapest in

August

Average price

$337
From Biloxi to San Diego
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One-way flight from Biloxi to San Diego
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Highest demand for flights based on searches. 15% potential increase in price ($90 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Biloxi to San Diego

Cheapest flights from Biloxi to San Diego
Explore the most affordable flight options available from Biloxi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:45 pmGPT - SAN
1 stop7h 35mDelta
Sat 11/156:15 amSAN - GPT
1 stop6h 23mDelta
Deal found 9/15$289
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:10 pmGPT - SAN
1 stop6h 10mAmerican Airlines
Sat 11/1510:09 amSAN - GPT
2 stops10h 59mAmerican Airlines
Deal found 9/15$294
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:08 amGPT - SAN
1 stop8h 20mDelta
Sat 10/410:55 amSAN - GPT
1 stop8h 44mDelta
Deal found 9/15$307
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:30 amGPT - SAN
2 stops8h 27mAmerican Airlines
Sat 10/41:02 pmSAN - GPT
1 stop7h 40mAmerican Airlines
Deal found 9/15$312
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/107:06 pmGPT - SAN
1 stop6h 34mAmerican Airlines
Tue 10/141:41 pmSAN - GPT
1 stop7h 55mAmerican Airlines
Deal found 9/14$314
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:05 pmGPT - SAN
1 stop7h 09mDelta
Mon 10/209:48 pmSAN - GPT
1 stop9h 28mDelta
Deal found 9/16$323
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:02 pmGPT - SAN
1 stop6h 57mAmerican Airlines
Thu 11/62:39 pmSAN - GPT
1 stop6h 28mAmerican Airlines
Deal found 9/14$344
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:15 pmGPT - SAN
1 stop6h 38mUnited Airlines
Tue 11/119:00 amSAN - GPT
2 stops10h 36mUnited Airlines
Deal found 9/14$347
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/242:05 pmGPT - SAN
1 stop7h 22mDelta
Mon 9/299:50 pmSAN - GPT
1 stop9h 29mDelta
Deal found 9/15$368

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Biloxi to San Diego that are best for you.

Fly from

Biloxi

Fly to

San Diego

Route

Depart

Return

Price

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Sat 11/8

3:45 pm-9:20 pm

1 stop7h 35m

San Diego

Sat 11/15

6:15 am-2:38 pm

1 stop6h 23m

$289

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Tue 9/30

6:08 am-12:28 pm

1 stop8h 20m

San Diego

Sat 10/4

10:55 am-9:39 pm

1 stop8h 44m

$307

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Fri 10/17

6:05 pm-11:14 pm

1 stop7h 09m

San Diego

Mon 10/20

9:48 pm-9:16 am

1 stop9h 28m

$323

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Wed 2/18

5:25 am-11:12 am

1 stop7h 47m

San Diego

Sat 2/21

6:27 am-5:33 pm

1 stop9h 06m

$339

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Sat 12/6

7:15 am-3:19 pm

2 stops10h 04m

San Diego

Thu 12/11

2:36 pm-10:53 pm

1 stop6h 17m

$344

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Sat 11/1

6:02 pm-10:59 pm

1 stop6h 57m

San Diego

Thu 11/6

2:39 pm-11:07 pm

1 stop6h 28m

$344

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Sat 11/8

12:10 pm-6:24 pm

2 stops8h 14m

San Diego

Sat 11/15

10:09 am-11:08 pm

2 stops10h 59m

$349

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Thu 11/6

12:48 pm-9:04 pm

1 stop10h 16m

San Diego

Tue 11/11

12:50 pm-11:36 pm

2 stops8h 46m

$349

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Sat 10/11

3:45 pm-11:14 pm

1 stop9h 29m

$149

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Mon 11/24

1:57 pm-12:13 am

2 stops12h 16m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 11 results
1
2

Best time to book a flight from Biloxi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to San Diego

What is the cheapest month to book a flight from Biloxi to San Diego?

Currently, August is the cheapest month in which you can book a flight from Biloxi to San Diego (average of $286). Flying from Biloxi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to SAN?

Find hourly flight availability from Biloxi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Biloxi to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Biloxi to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to San Diego. Price data was last updated on November 18, 2024.

Travelers seeking maximum savings on their Biloxi to San Diego flight should consider departing on Friday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Biloxi to San Diego?

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 16, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Biloxi to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Biloxi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Biloxi?

    If you book a flight to San Diego from Biloxi, you will be flying to San Diego, which is the city’s only airport. San Diego (SAN) is located 2.6 mi from the center of San Diego. There are 0 flights from Biloxi to San Diego per day from 7 different airlines.

  • How popular is this Biloxi to San Diego flight route?

    Flights from Biloxi to San Diego have been viewed 3 times in the past calendar month.

  • How long is the flight from Biloxi to San Diego?

    For as low as $289, Delta can have you in San Diego from Biloxi in 7h 35m. Biloxi and San Diego are separated by a distance of 1658 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Biloxi to San Diego?

    Looking for the cheapest flight from Biloxi to San Diego? While on average our users pay $384, our data indicates the cheapest price to be $123. The most popular route (Gulfport Biloxi Regional - San Diego), is priced around $289.

  • Can I find deals for flights from Biloxi to San Diego that include hotel bookings?

    Yes. In addition to deals on Biloxi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to San Diego.

  • Can I find deals for business class flights from Biloxi to San Diego?

    Yes. Cheapflights offers flight deals from Biloxi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Biloxi to San Diego (average of $286). Flying from Biloxi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City

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Top 7 airlines flying from Biloxi to San Diego

Discover the top 7 airlines that operate flights from Biloxi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$128Average$218FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$151Average$214FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$216Average$390FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$252Average$457FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$279FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$259Average$481FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$288Average$474FlexibilityNo cancel feeOn-time63%

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