Leaving on a Wednesday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 89% on the overall cost on flights from Columbia, Missouri to Rome.
A simple way to save on the total cost of your ticket is to fly from Columbia, Missouri to Rome in the morning. If you’re flexible enough to do this you can expect to save up to 3% on your trip compared to booking a flight at noon.