Leaving on a Saturday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 112% on the overall cost on flights from Appleton to Rome.
A simple way to save on the total cost of your ticket is to fly from Appleton to Rome at noon. If you’re flexible enough to do this you can expect to save up to 57% on your trip compared to booking a flight in the morning.