$298+ Cheap flights from San Diego to Roanoke (SAN - ROA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — ROA
Aug 11 — Aug 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to Roanoke with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Roanoke
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to RoanokeExplore the most affordable flight options available from San Diego to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 12, 2026.
Explore the most affordable flight options available from San Diego to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 12, 2026.
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:45 am
SAN
- ROA
1 stop9h 36m
American Airlines
Sat 9/1212:11 pm
ROA
- SAN
1 stop10h 06m
American Airlines
Deal found 7/9![American Airlines logo]()
$341
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:25 pm
SAN
- ROA
1 stop8h 21m
United Airlines
Sat 8/153:00 pm
ROA
- SAN
2 stops10h 10m
United Airlines
Deal found 7/8![United Airlines logo]()
$346
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:45 pm
SAN
- ROA
1 stop9h 03m
United Airlines
Sat 8/296:40 am
ROA
- SAN
1 stop7h 35m
United Airlines
Deal found 7/8![United Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:00 pm
SAN
- ROA
1 stop7h 27m
Delta
Mon 8/176:00 am
ROA
- SAN
1 stop8h 07m
Delta
Deal found 7/12![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:45 pm
SAN
- ROA
1 stop9h 48m
Delta
Mon 10/126:00 am
ROA
- SAN
1 stop8h 16m
Delta
Deal found 7/11![Delta logo]()
$394
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:28 pm
SAN
- ROA
1 stop9h 12m
American Airlines
Sat 8/153:08 pm
ROA
- SAN
1 stop8h 27m
American Airlines
Deal found 7/9![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:40 pm
SAN
- ROA
1 stop8h 01m
United Airlines
Mon 8/173:00 pm
ROA
- SAN
2 stops10h 10m
United Airlines
Deal found 7/12![United Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:19 pm
SAN
- ROA
1 stop7h 40m
American Airlines
Thu 8/65:35 pm
ROA
- SAN
1 stop9h 12m
American Airlines
Deal found 7/11![American Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:41 pm
SAN
- ROA
1 stop8h 47m
Delta
Mon 10/196:40 pm
ROA
- SAN
1 stop7h 35m
Delta
Deal found 7/8![Delta logo]()
$444
Best flights from San Diego to RoanokeDiscover carefully curated flight deals from San Diego to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 12, 2026.
Discover carefully curated flight deals from San Diego to Roanoke that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 12, 2026.
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:30 pm
SAN
- ROA
1 stop8h 39m
United Airlines
Tue 9/1510:26 am
ROA
- SAN
2 stops10h 02m
United Airlines
Deal found 7/8![United Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:28 pm
SAN
- ROA
1 stop9h 12m
American Airlines
Sat 8/153:08 pm
ROA
- SAN
1 stop8h 27m
American Airlines
Deal found 7/10![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:40 pm
SAN
- ROA
1 stop8h 29m
United Airlines
Mon 9/73:00 pm
ROA
- SAN
1 stop8h 29m
United Airlines
Deal found 7/8![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:40 pm
SAN
- ROA
1 stop8h 01m
United Airlines
Mon 8/173:00 pm
ROA
- SAN
2 stops10h 10m
United Airlines
Deal found 7/12![United Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:28 pm
SAN
- ROA
2 stops12h 34m
United Airlines
Tue 9/296:49 am
ROA
- SAN
1 stop7h 36m
United Airlines
Deal found 7/9![United Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:28 pm
SAN
- ROA
2 stops12h 13m
United Airlines
Sat 9/126:40 am
ROA
- SAN
2 stops10h 04m
United Airlines
Deal found 7/9![United Airlines logo]()
$461
Last-minute flights from San Diego to RoanokeDiscover last-minute flight deals from San Diego to Roanoke. Data last updated July 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Roanoke. Data last updated July 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1910:28 pm
SAN
- ROA
1 stop9h 12m
American Airlines
Thu 7/303:10 pm
ROA
- SAN
1 stop8h 40m
American Airlines
Deal found 7/9![American Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:28 pm
SAN
- ROA
1 stop9h 12m
American Airlines
Sat 8/153:08 pm
ROA
- SAN
1 stop8h 27m
American Airlines
Deal found 7/9![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:19 pm
SAN
- ROA
1 stop7h 40m
American Airlines
Thu 8/65:35 pm
ROA
- SAN
1 stop9h 12m
American Airlines
Deal found 7/11![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:59 pm
SAN
- ROA
1 stop8h 43m
United Airlines
Sat 8/155:50 pm
ROA
- SAN
1 stop7h 20m
United Airlines
Deal found 7/8![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:15 am
SAN
- ROA
1 stop7h 50m
American Airlines
Sat 8/159:07 am
ROA
- SAN
2 stops9h 19m
American Airlines
Deal found 7/12![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:00 pm
SAN
- ROA
1 stop7h 27m
Delta
Mon 8/176:00 am
ROA
- SAN
1 stop8h 07m
Delta
Deal found 7/12![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:40 pm
SAN
- ROA
1 stop8h 01m
United Airlines
Mon 8/173:00 pm
ROA
- SAN
2 stops10h 10m
United Airlines
Deal found 7/12![United Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:45 pm
SAN
- ROA
1 stop9h 03m
United Airlines
Sat 8/296:40 am
ROA
- SAN
1 stop7h 35m
United Airlines
Deal found 7/8![United Airlines logo]()
$355
One-way flights from San Diego to RoanokeSearch for one-way flight options from San Diego to Roanoke. Find affordable one-way fares based on user searches. Data last updated July 12, 2026.
Search for one-way flight options from San Diego to Roanoke. Find affordable one-way fares based on user searches. Data last updated July 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/223:03 pm
SAN
- ROA
2 stops20h 03m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:35 am
SAN
- ROA
2 stops28h 31m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2610:00 am
SAN
- ROA
2 stops26h 50m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/244:12 pm
SAN
- ROA
3 stops42h 54m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:24 pm
SAN
- ROA
2 stops46h 42m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:36 am
SAN
- ROA
1 stop8h 07m
Delta
Deal found 7/8![Delta logo]()
$461
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:27 pm
SAN
- ROA
2 stops12h 15m
United Airlines
Deal found 7/9![United Airlines logo]()
$466
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/234:12 pm
SAN
- ROA
2 stops20h 38m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$473
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/239:59 pm
SAN
- ROA
1 stop8h 43m
United Airlines
Deal found 7/8![United Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/249:41 am
SAN
- ROA
2 stops11h 18m
American Airlines
Deal found 7/8![American Airlines logo]()
$493
Find flight deals from San Diego to Roanoke
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Roanoke (ROA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $341 (American Airlines) |
One-way from | $298 (Kiwi.com) |
Popular in | August |
Cheapest in | September |
Average price | $447 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
Use the filters below to find and compare flights from San Diego to Roanoke that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Fri 9/11
10:30 pm-10:09 am
1 stop8h 39m
Roanoke
Tue 9/15
10:26 am-5:28 pm
2 stops10h 02m
$346
Quickest round-trip
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Thu 9/3
10:40 pm-10:09 am
1 stop8h 29m
Roanoke
Mon 9/7
3:00 pm-8:29 pm
1 stop8h 29m
$369
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Thu 7/23
10:28 pm-10:40 am
1 stop9h 12m
Roanoke
Sat 8/15
3:08 pm-8:35 pm
1 stop8h 27m
$395
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Fri 8/14
10:40 pm-9:41 am
1 stop8h 01m
Roanoke
Mon 8/17
3:00 pm-10:10 pm
2 stops10h 10m
$396
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Sat 9/26
6:28 pm-10:02 am
2 stops12h 34m
Roanoke
Tue 9/29
6:49 am-11:25 am
1 stop7h 36m
$456
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Tue 9/1
6:28 pm-9:41 am
2 stops12h 13m
Roanoke
Sat 9/12
6:40 am-1:44 pm
2 stops10h 04m
$461
Cheapest one-way
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Sat 7/25
10:36 am-9:43 pm
1 stop8h 07m
$461
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Sat 7/25
9:59 pm-9:42 am
1 stop8h 43m
$461
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Thu 7/23
9:59 pm-9:42 am
1 stop8h 43m
$488
San DiegoRoanoke
SAN - ROA
SANROA
San Diego
Fri 7/24
9:30 pm-10:30 am
1 stop10h 00m
$488
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from San Diego to Roanoke
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Roanoke in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Roanoke flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Roanoke flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Roanoke flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Roanoke flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Roanoke flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Roanoke
Have a flexible travel schedule? Discover the best time to fly to Roanoke from San Diego with our price prediction graph.
SAN-ROA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Roanoke
Reviews of airlines servicing Roanoke
Get insights into the airlines that provide service to Roanoke. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Roanoke. Reviews last updated July 12, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from San Diego to Roanoke have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.8
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.8
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.8
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Roanoke?
Book flights to Roanoke if you plan to visit one of these locationsSalem
Radford
Blacksburg
Christiansburg
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from San Diego
Popular flights
Roanoke flight routes
Alternative routes for San Diego to Roanoke
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Roanoke by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Roanoke by cabin class
Find flights from San Diego to Roanoke, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Roanoke flights
Browse other San Diego and Roanoke flight options. Last updated on July 12, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on July 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Roanoke
Explore flights to Roanoke departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 12, 2026.
Top 3 airlines flying from San Diego to Roanoke
Discover the top 3 airlines that operate flights from San Diego to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$497 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$510 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$478 | FlexibilityNo cancel fee | On-timeN/A |