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Roanoke

$269+ Cheap flights from Iowa to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Jul 7 — Jul 141
Tue 7/7
Tue 7/14
1 adult, Economy
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Cheap flight deals from Iowa to Roanoke

Cheapest flights from Iowa to Roanoke
Explore the most affordable flight options available from Iowa to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.

This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:00 pm
DSM
-
ROA
1 stop6h 32m
Delta
Sun 7/56:00 am
ROA
-
DSM
1 stop5h 45m
Delta
Deal found 6/2$309
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:09 pm
MLI
-
ROA
1 stop5h 41m
Delta
Mon 9/216:00 am
ROA
-
MLI
1 stop5h 23m
Delta
Deal found 6/4$309
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:35 pm
DSM
-
ROA
2 stops9h 24m
American Airlines
Fri 7/107:53 pm
ROA
-
DSM
1 stop5h 16m
American Airlines
Deal found 6/2$314
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:24 pm
MLI
-
ROA
1 stop4h 56m
American Airlines
Tue 7/74:48 pm
ROA
-
MLI
2 stops8h 53m
American Airlines
Deal found 6/5$314
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:41 pm
DSM
-
ROA
1 stop6h 39m
American Airlines
Sun 7/57:53 pm
ROA
-
DSM
1 stop5h 16m
American Airlines
Deal found 6/6$319
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:09 pm
MLI
-
ROA
1 stop6h 18m
Delta
Tue 9/86:00 am
ROA
-
MLI
1 stop5h 26m
Delta
Deal found 6/6$319
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:20 pm
MLI
-
ROA
1 stop4h 58m
American Airlines
Mon 7/66:00 am
ROA
-
MLI
1 stop6h 23m
American Airlines
Deal found 6/2$324
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/184:24 pm
MLI
-
ROA
1 stop4h 56m
American Airlines
Mon 6/226:02 pm
ROA
-
MLI
2 stops7h 09m
American Airlines
Deal found 6/3$344
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/131:37 pm
DSM
-
ROA
1 stop7h 43m
American Airlines
Tue 6/167:58 pm
ROA
-
DSM
1 stop5h 14m
American Airlines
Deal found 6/2$369
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
DSM
-
ROA
2 stops6h 55m
United Airlines
Tue 7/72:30 pm
ROA
-
DSM
2 stops9h 26m
United Airlines
Deal found 6/2$375
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:26 am
DSM
-
ROA
1 stop5h 34m
American Airlines
Sun 8/95:30 pm
ROA
-
DSM
1 stop7h 50m
American Airlines
Deal found 6/3$378
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:00 am
DSM
-
ROA
2 stops10h 14m
American Airlines
Tue 7/142:51 pm
ROA
-
DSM
2 stops10h 10m
American Airlines
Deal found 6/5$381

Find flight deals from Iowa to Roanoke

Keep the following information in mind while searching for Iowa to Roanoke flight deals. Data was last updated June 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(Delta)

One-way from

$269
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$448
Provider with most accurate pricing for Des Moines-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Roanoke flights.
Search Deals
From Iowa to Roanoke
Search Deals
One-way flight from Iowa to Roanoke
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from Iowa to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 7/2

5:00 pm-12:32 am

1 stop6h 32m

Roanoke

Sun 7/5

6:00 am-10:45 am

1 stop5h 45m

$309

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 7/3

1:41 pm-10:18 pm

1 stop7h 37m

Roanoke

Fri 7/10

7:53 pm-12:09 am

1 stop5h 16m

$309

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Mon 9/7

5:09 pm-11:50 pm

1 stop5h 41m

Roanoke

Sun 9/20

6:00 am-10:23 am

1 stop5h 23m

$309

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Wed 7/1

4:24 pm-10:20 pm

1 stop4h 56m

Roanoke

Tue 7/7

6:00 am-11:23 am

1 stop6h 23m

$309

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Fri 9/11

11:00 am-7:16 pm

1 stop7h 16m

Roanoke

Sat 9/26

6:00 am-10:23 am

1 stop5h 23m

$309

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Thu 9/10

5:00 pm-11:50 pm

1 stop5h 50m

Roanoke

Sun 9/20

6:00 am-10:23 am

1 stop5h 23m

$309

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Fri 7/17

5:05 pm-12:25 am

1 stop6h 20m

Roanoke

Tue 7/21

6:00 am-10:12 am

1 stop5h 12m

$309

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 6/30

11:23 am-11:44 pm

2 stops11h 21m

Roanoke

Tue 7/7

10:47 am-2:27 pm

1 stop4h 40m

$314

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 7/7

5:00 am-4:14 pm

2 stops10h 14m

Roanoke

Tue 7/14

7:53 pm-12:09 am

1 stop5h 16m

$314

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Fri 7/3

11:43 am-11:59 pm

2 stops11h 16m

Roanoke

Mon 7/6

6:00 am-11:23 am

1 stop6h 23m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/2

Showing 1-10 of 23 resultsSorted by cheapest first
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3

Best time to book a flight from Iowa to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Roanoke

How much does it cost to fly round-trip from Iowa to Roanoke?

Related info for your journey

Find useful and relevant information for your journey from Iowa to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from Iowa?

    Roanoke (ROA) is the airport you will fly into if you book a flight from Iowa to Roanoke. It is only a 4.2 mi journey from Roanoke (ROA) to Roanoke’s city center.

  • How long is the flight from Iowa to Roanoke?

    For as low as $309, American Airlines can have you in Roanoke from Iowa in 6h 32m. There are 784 mi between Iowa and Roanoke. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Roanoke?

    The most popular flight routes from Iowa to Roanoke are Des Moines - Roanoke, Moline Quad-City - Roanoke and Cedar Rapids - Roanoke.

  • Can I find deals for flights from Iowa to Roanoke that include hotel bookings?

    Yes. In addition to deals on Iowa to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Roanoke.

  • Can I find deals for business class flights from Iowa to Roanoke?

    Yes. Cheapflights offers flight deals from Iowa to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Salem
Radford
Blacksburg
Christiansburg

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Alternative routes for Iowa to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Iowa to Roanoke

Discover the top airline that operate flights from Iowa to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$400FlexibilityNo cancel feeOn-time71%

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