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Roanoke

$222+ Cheap flights from Iowa to Roanoke (ROA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Iowa to Roanoke

Cheapest flights from Iowa to Roanoke
Explore the most affordable flight options available from Iowa to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:20 pm
DSM
-
ROA
1 stop5h 44m
Delta
Wed 4/156:00 am
ROA
-
DSM
1 stop6h 05m
Delta
Deal found 2/12$269
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:25 pm
DSM
-
ROA
2 stops6h 39m
Delta
Wed 4/156:00 am
ROA
-
DSM
1 stop6h 05m
Delta
Deal found 2/12$274
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:41 pm
DSM
-
ROA
1 stop4h 53m
Delta
Sun 5/246:00 am
ROA
-
DSM
1 stop6h 03m
Delta
Deal found 2/10$279
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:26 pm
MLI
-
ROA
1 stop5h 47m
United Airlines
Fri 5/296:47 am
ROA
-
MLI
1 stop4h 12m
United Airlines
Deal found 2/11$287
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:20 pm
DSM
-
ROA
1 stop5h 44m
Delta
Sat 4/116:00 am
ROA
-
DSM
1 stop5h 48m
Delta
Deal found 2/12$304
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
DSM
-
ROA
2 stops9h 33m
American Airlines
Tue 3/37:33 am
ROA
-
DSM
1 stop6h 31m
American Airlines
Deal found 2/12$305
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:25 pm
DSM
-
ROA
2 stops6h 39m
Delta
Wed 4/156:00 am
ROA
-
DSM
1 stop6h 05m
Delta
Deal found 2/12$309
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:16 pm
MLI
-
ROA
1 stop6h 18m
Delta
Fri 5/296:00 am
ROA
-
MLI
1 stop5h 15m
Delta
Deal found 2/11$313
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:15 am
DSM
-
ROA
2 stops7h 24m
Delta
Sat 5/236:00 am
ROA
-
DSM
1 stop6h 03m
Delta
Deal found 2/11$324
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:15 pm
DSM
-
ROA
1 stop4h 24m
United Airlines
Tue 11/105:38 pm
ROA
-
DSM
1 stop4h 34m
United Airlines
Deal found 2/11$339
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:56 am
DSM
-
ROA
2 stops7h 37m
American Airlines
Sun 5/247:58 pm
ROA
-
DSM
1 stop5h 01m
American Airlines
Deal found 2/10$357
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:41 pm
DSM
-
ROA
1 stop4h 53m
Delta
Tue 5/196:00 am
ROA
-
DSM
2 stops8h 59m
Delta
Deal found 2/12$359

Find flight deals from Iowa to Roanoke

Keep the following information in mind while searching for Iowa to Roanoke flight deals. Data was last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

One-way from

$222
(American Airlines)

Popular in

February

Cheapest in

June

Average price

$441
Provider with most accurate pricing for Des Moines-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Roanoke flights.
Search Deals
From Iowa to Roanoke
Search Deals
One-way flight from Iowa to Roanoke
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Iowa to Roanoke that are best for you.

Fly from

Iowa

Fly to

Roanoke

Route

Depart

Return

Price

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 4/11

5:20 pm-12:04 am

1 stop5h 44m

Roanoke

Wed 4/15

6:00 am-11:05 am

1 stop6h 05m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 4/7

5:20 pm-12:04 am

1 stop5h 44m

Roanoke

Wed 4/15

6:00 am-11:05 am

1 stop6h 05m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Mon 4/6

5:20 pm-12:04 am

1 stop5h 44m

Roanoke

Tue 4/14

6:00 am-11:05 am

1 stop6h 05m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Wed 5/20

6:41 pm-12:34 am

1 stop4h 53m

Roanoke

Sun 5/24

6:00 am-11:03 am

1 stop6h 03m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 4/11

5:20 pm-12:04 am

1 stop5h 44m

Roanoke

Tue 4/14

6:00 am-11:05 am

1 stop6h 05m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 5/16

6:41 pm-12:34 am

1 stop4h 53m

Roanoke

Sat 5/23

6:00 am-11:03 am

1 stop6h 03m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Mon 4/6

5:20 pm-12:04 am

1 stop5h 44m

Roanoke

Wed 4/15

6:00 am-11:05 am

1 stop6h 05m

$269

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 2/27

6:00 am-4:33 pm

2 stops9h 33m

Roanoke

Tue 3/3

7:33 am-1:04 pm

1 stop6h 31m

$305

Cedar RapidsRoanoke

CID - ROA

CIDROA

Cedar Rapids

Sun 3/1

6:40 pm-11:57 pm

1 stop4h 17m

Roanoke

Sat 3/7

8:00 pm-8:13 am

2 stops13h 13m

$520

Cedar RapidsRoanoke

CID - ROA

CIDROA

Cedar Rapids

Sun 3/1

6:35 am-10:08 am

1 stop26h 33m

Roanoke

Sat 3/7

5:35 pm-11:01 pm

1 stop6h 26m

$568

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

Showing 1-10 of 17 results
1
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Best time to book a flight from Iowa to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Roanoke

What is the cheapest month to book a flight from Iowa to Roanoke?

Currently, May is the cheapest month in which you can book a flight from Iowa to Roanoke (average of $248). Flying from Iowa to Roanoke in December is currently the most expensive (average of $350). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from Iowa?

    Roanoke (ROA) is the airport you will fly into if you book a flight from Iowa to Roanoke. It is only a 4.2 mi journey from Roanoke (ROA) to Roanoke’s city center.

  • How long is the flight from Iowa to Roanoke?

    For as low as $520, Delta can have you in Roanoke from Iowa in 4h 17m. There are 698 mi between Iowa and Roanoke. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Roanoke?

    The most popular flight routes from Iowa to Roanoke are Des Moines - Roanoke, Moline Quad-City - Roanoke and Cedar Rapids - Roanoke.

  • Can I find deals for flights from Iowa to Roanoke that include hotel bookings?

    Yes. In addition to deals on Iowa to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Roanoke.

  • Can I find deals for business class flights from Iowa to Roanoke?

    Yes. Cheapflights offers flight deals from Iowa to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Roanoke?

    Currently, May is the cheapest month in which you can book a flight from Iowa to Roanoke (average of $248). Flying from Iowa to Roanoke in December is currently the most expensive (average of $350). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Salem
Radford
Blacksburg
Christiansburg

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Alternative routes for Iowa to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Roanoke

Discover the top 2 airlines that operate flights from Iowa to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$235Average$401FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$323FlexibilityNo cancel feeOn-timeN/A

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