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Roanoke

$328+ Cheap flights from Iowa to Roanoke (ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Apr 23 — Apr 301
Thu 4/23
Thu 4/30
1 adult, Economy
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Cheap flight deals from Iowa to Roanoke

Cheapest flights from Iowa to Roanoke
Explore the most affordable flight options available from Iowa to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.

This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:02 pm
DSM
-
ROA
1 stop6h 24m
American Airlines
Wed 5/137:28 am
ROA
-
DSM
1 stop7h 18m
American Airlines
Deal found 3/22$328
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:01 pm
DSM
-
ROA
1 stop6h 13m
American Airlines
Sat 5/237:58 pm
ROA
-
DSM
1 stop5h 19m
American Airlines
Deal found 3/24$329
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:52 pm
CID
-
ROA
1 stop4h 18m
American Airlines
Mon 4/278:00 pm
ROA
-
CID
1 stop4h 47m
American Airlines
Deal found 3/23$329
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:56 pm
MLI
-
ROA
1 stop4h 28m
American Airlines
Fri 5/296:00 am
ROA
-
MLI
1 stop5h 37m
American Airlines
Deal found 3/20$329
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:41 pm
MLI
-
ROA
1 stop4h 29m
American Airlines
Sat 5/211:51 am
ROA
-
MLI
2 stops7h 16m
American Airlines
Deal found 3/23$334
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:20 am
DSM
-
ROA
1 stop6h 09m
United Airlines
Wed 4/85:45 pm
ROA
-
DSM
1 stop4h 47m
United Airlines
Deal found 3/20$339
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:34 am
CID
-
ROA
1 stop5h 55m
United Airlines
Sat 4/116:45 am
ROA
-
CID
1 stop4h 50m
United Airlines
Deal found 3/23$339
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:30 am
MLI
-
ROA
1 stop5h 59m
United Airlines
Sat 4/115:45 pm
ROA
-
MLI
1 stop4h 26m
United Airlines
Deal found 3/23$339
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
CID
-
ROA
2 stops9h 53m
American Airlines
Sat 4/117:28 am
ROA
-
CID
1 stop5h 50m
American Airlines
Deal found 3/23$344
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/712:52 pm
MLI
-
ROA
1 stop6h 56m
American Airlines
Sat 4/117:00 am
ROA
-
MLI
2 stops9h 18m
American Airlines
Deal found 3/23$344
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:16 pm
DSM
-
ROA
1 stop4h 21m
United Airlines
Mon 4/202:55 pm
ROA
-
DSM
2 stops7h 37m
United Airlines
Deal found 3/19$364
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:39 pm
DSM
-
ROA
1 stop4h 50m
Delta
Sun 7/56:00 am
ROA
-
DSM
1 stop5h 55m
Delta
Deal found 3/22$384

Find flight deals from Iowa to Roanoke

Keep the following information in mind while searching for Iowa to Roanoke flight deals. Data was last updated March 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$328
(American Airlines)

Popular in

February

Cheapest in

June

Average price

$368
Provider with most accurate pricing for Des Moines-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Roanoke flights.
Search Deals
From Iowa to Roanoke
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Iowa to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Sat 5/16

5:01 pm-12:14 am

1 stop6h 13m

Roanoke

Sat 5/23

7:58 pm-12:17 am

1 stop5h 19m

$329

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 4/17

7:16 pm-12:37 am

1 stop4h 21m

Roanoke

Mon 4/20

5:45 pm-11:17 pm

1 stop6h 32m

$329
Quickest round-trip

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Fri 5/22

6:34 pm-12:24 am

1 stop4h 50m

Roanoke

Sun 5/24

5:47 pm-9:04 pm

1 stop4h 17m

$329

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Thu 4/30

6:41 pm-12:10 am

1 stop4h 29m

Roanoke

Sat 5/2

7:00 am-12:27 pm

1 stop6h 27m

$329

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Wed 5/6

8:56 am-5:33 pm

2 stops7h 37m

Roanoke

Wed 5/13

7:28 am-1:46 pm

1 stop7h 18m

$333

Cedar RapidsRoanoke

CID - ROA

CIDROA

Cedar Rapids

Wed 4/8

6:34 am-1:29 pm

1 stop5h 55m

Roanoke

Sat 4/11

6:45 am-10:35 am

1 stop4h 50m

$339

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Wed 4/8

2:02 pm-9:26 pm

1 stop6h 24m

Roanoke

Sun 4/12

7:28 am-1:46 pm

1 stop7h 18m

$339

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Tue 4/7

6:30 am-1:29 pm

1 stop5h 59m

Roanoke

Sat 4/11

5:45 pm-9:11 pm

1 stop4h 26m

$339

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Tue 4/7

12:52 pm-8:48 pm

1 stop6h 56m

Roanoke

Sat 4/11

7:00 am-3:18 pm

2 stops9h 18m

$344

Cedar RapidsRoanoke

CID - ROA

CIDROA

Cedar Rapids

Thu 5/21

6:50 pm-12:24 am

1 stop4h 34m

Roanoke

Sun 5/24

6:40 am-11:58 am

1 stop6h 18m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Iowa to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Roanoke

What is the cheapest month to book a flight from Iowa to Roanoke?

Currently, May is the cheapest month in which you can book a flight from Iowa to Roanoke (average of $248). Flying from Iowa to Roanoke in December is currently the most expensive (average of $350). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Iowa to Roanoke?

Related info for your journey

Find useful and relevant information for your journey from Iowa to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from Iowa?

    Roanoke (ROA) is the airport you will fly into if you book a flight from Iowa to Roanoke. It is only a 4.2 mi journey from Roanoke (ROA) to Roanoke’s city center.

  • How long is the flight from Iowa to Roanoke?

    For as low as $329, American Airlines can have you in Roanoke from Iowa in 4h 21m. There are 784 mi between Iowa and Roanoke. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Roanoke?

    The most popular flight routes from Iowa to Roanoke are Des Moines - Roanoke, Cedar Rapids - Roanoke and Moline Quad-City - Roanoke.

  • Can I find deals for flights from Iowa to Roanoke that include hotel bookings?

    Yes. In addition to deals on Iowa to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Roanoke.

  • Can I find deals for business class flights from Iowa to Roanoke?

    Yes. Cheapflights offers flight deals from Iowa to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Roanoke?

    Currently, May is the cheapest month in which you can book a flight from Iowa to Roanoke (average of $248). Flying from Iowa to Roanoke in December is currently the most expensive (average of $350). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Salem
Radford
Blacksburg
Christiansburg

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Alternative routes for Iowa to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Roanoke

Discover the top 2 airlines that operate flights from Iowa to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$235Average$363FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$318FlexibilityNo cancel feeOn-timeN/A

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