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Roanoke

$269+ Cheap flights from Iowa to Roanoke (ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROA
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
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Cheap flight deals from Iowa to Roanoke

Cheapest flights from Iowa to Roanoke
Explore the most affordable flight options available from Iowa to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:41 pm
DSM
-
ROA
1 stop4h 53m
Delta
Sat 5/236:00 am
ROA
-
DSM
1 stop6h 03m
Delta
Deal found 2/2$269
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:26 pm
MLI
-
ROA
1 stop5h 47m
United Airlines
Sat 5/306:47 am
ROA
-
MLI
1 stop4h 12m
United Airlines
Deal found 2/4$286
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:28 pm
CID
-
ROA
1 stop4h 29m
American Airlines
Sat 2/217:33 am
ROA
-
CID
1 stop6h 12m
American Airlines
Deal found 2/2$309
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/193:52 pm
MLI
-
ROA
1 stop3h 57m
United Airlines
Mon 2/236:40 am
ROA
-
MLI
1 stop4h 31m
United Airlines
Deal found 2/4$324
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:05 pm
DSM
-
ROA
1 stop6h 34m
United Airlines
Tue 11/107:00 am
ROA
-
DSM
1 stop4h 20m
United Airlines
Deal found 2/3$339
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/75:00 pm
DSM
-
ROA
1 stop5h 42m
American Airlines
Mon 2/95:14 pm
ROA
-
DSM
1 stop6h 54m
American Airlines
Deal found 2/3$369
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:26 pm
MLI
-
ROA
1 stop5h 47m
United Airlines
Fri 5/296:47 am
ROA
-
MLI
1 stop4h 12m
United Airlines
Deal found 2/4$369
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:02 pm
MLI
-
ROA
1 stop8h 50m
American Airlines
Mon 3/27:33 am
ROA
-
MLI
1 stop17h 04m
American Airlines
Deal found 2/3$372
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/73:35 pm
DSM
-
ROA
1 stop4h 36m
United Airlines
Mon 2/92:55 pm
ROA
-
DSM
2 stops7h 55m
United Airlines
Deal found 2/3$374
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:01 pm
DSM
-
ROA
1 stop6h 13m
American Airlines
Sat 5/235:41 pm
ROA
-
DSM
2 stops7h 18m
American Airlines
Deal found 2/3$377
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:41 pm
CID
-
ROA
1 stop5h 08m
United Airlines
Wed 2/186:40 am
ROA
-
CID
1 stop6h 35m
United Airlines
Deal found 2/3$379
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/143:52 pm
MLI
-
ROA
1 stop3h 57m
United Airlines
Wed 2/186:40 am
ROA
-
MLI
1 stop4h 31m
United Airlines
Deal found 2/3$379

Find flight deals from Iowa to Roanoke

Keep the following information in mind while searching for Iowa to Roanoke flight deals. Data was last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

Popular in

February

Cheapest in

August

Average price

$735
Provider with most accurate pricing for Des Moines-Roanoke flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Roanoke flights.
Search Deals
From Iowa to Roanoke
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($103 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($38 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Iowa to Roanoke that are best for you.

Fly from

Iowa

Fly to

Roanoke

Route

Depart

Return

Price

Cedar RapidsRoanoke

CID - ROA

CIDROA

Cedar Rapids

Tue 2/17

6:28 pm-11:57 pm

1 stop4h 29m

Roanoke

Sat 2/21

7:33 am-12:45 pm

1 stop6h 12m

$309

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Thu 2/19

3:52 pm-8:49 pm

1 stop3h 57m

Roanoke

Mon 2/23

6:40 am-10:11 am

1 stop4h 31m

$324

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Sat 5/23

2:26 pm-9:13 pm

1 stop5h 47m

Roanoke

Fri 5/29

6:47 am-9:59 am

1 stop4h 12m

$369

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Sat 2/28

2:02 pm-11:52 pm

1 stop8h 50m

Roanoke

Mon 3/2

7:33 am-11:37 pm

1 stop17h 04m

$372

Cedar RapidsRoanoke

CID - ROA

CIDROA

Cedar Rapids

Fri 4/17

5:24 pm-12:17 am

1 stop5h 53m

Roanoke

Sun 4/19

8:37 am-12:47 pm

1 stop5h 10m

$379

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Wed 4/1

1:52 pm-9:25 pm

1 stop6h 33m

Roanoke

Mon 4/6

7:50 am-6:19 pm

1 stop11h 29m

$381

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Thu 2/12

9:04 am-8:49 pm

2 stops10h 45m

Roanoke

Mon 2/16

5:33 pm-9:41 pm

1 stop5h 08m

$389

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Fri 2/13

8:00 am-8:07 pm

2 stops11h 07m

Roanoke

Mon 2/16

5:33 pm-9:41 pm

1 stop5h 08m

$402

MolineRoanoke

MLI - ROA

MLIROA

Moline Quad-City

Thu 2/19

6:00 am-4:33 pm

2 stops9h 33m

Roanoke

Mon 2/23

7:33 am-1:00 pm

1 stop6h 27m

$417

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Wed 4/1

6:20 am-2:13 pm

2 stops6h 53m

Roanoke

Mon 4/6

7:59 pm-10:44 am

2 stops15h 45m

$423

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 21 results
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Best time to book a flight from Iowa to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Roanoke

What is the cheapest month to book a flight from Iowa to Roanoke?

Currently, May is the cheapest month in which you can book a flight from Iowa to Roanoke (average of $248). Flying from Iowa to Roanoke in December is currently the most expensive (average of $350). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Roanoke from Iowa?

    Roanoke (ROA) is the airport you will fly into if you book a flight from Iowa to Roanoke. It is only a 4.2 mi journey from Roanoke (ROA) to Roanoke’s city center.

  • How long is the flight from Iowa to Roanoke?

    For as low as $324, American Airlines can have you in Roanoke from Iowa in 3h 57m. There are 629 mi between Iowa and Roanoke. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Roanoke?

    The most popular flight routes from Iowa to Roanoke are Des Moines - Roanoke, Moline Quad-City - Roanoke and Cedar Rapids - Roanoke.

  • Can I find deals for flights from Iowa to Roanoke that include hotel bookings?

    Yes. In addition to deals on Iowa to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Roanoke.

  • Can I find deals for business class flights from Iowa to Roanoke?

    Yes. Cheapflights offers flight deals from Iowa to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Roanoke?

    Currently, May is the cheapest month in which you can book a flight from Iowa to Roanoke (average of $248). Flying from Iowa to Roanoke in December is currently the most expensive (average of $350). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Salem
Radford
Blacksburg
Christiansburg

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Alternative routes for Iowa to Roanoke

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Roanoke

Discover the top 2 airlines that operate flights from Iowa to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$235Average$401FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$323FlexibilityNo cancel feeOn-timeN/A

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