HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Punta Arenas

$2,014+ Cheap flights from Des Moines (DSM) to Punta Arenas (PUQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PUQ
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Punta Arenas with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Punta Arenas

Best flights from Des Moines to Punta Arenas
Discover carefully curated flight deals from Des Moines to Punta Arenas that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

This eDestinos deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/241:03 pmDSM - PUQ
3 stops65h 23mMultiple Airlines
Sat 1/3111:15 pmPUQ - DSM
2 stops50h 14mMultiple Airlines
Deal found 12/10$2,014
This Bravofly deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/255:16 pmDSM - PUQ
2 stops50h 50mLATAM Airlines
Sat 1/311:19 amPUQ - DSM
2 stops36h 22mLATAM Airlines
Deal found 12/11$2,020
This eDestinos deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/241:03 pmDSM - PUQ
2 stops34h 02mLATAM Airlines
Sat 1/3111:15 pmPUQ - DSM
2 stops50h 14mLATAM Airlines
Deal found 12/10$2,656

Find flight deals from Des Moines to Punta Arenas

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Punta Arenas (PUQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$2,014
(eDestinos)
Provider with most accurate pricing for Des Moines-Punta Arenas Pres Ibanez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Punta Arenas Pres Ibanez flights.
Search Deals
From Des Moines to Punta Arenas Pres Ibanez
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Punta Arenas that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Punta Arenas that are best for you.

Fly from

Des Moines

Fly to

Punta Arenas

Route

Depart

Return

Price

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Sat 1/24

1:03 pm-9:26 am

3 stops65h 23m

Punta Arenas Pres Ibanez

Sat 1/31

11:15 pm-10:29 pm

2 stops50h 14m

$2,014

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Sun 1/25

5:16 pm-11:06 pm

2 stops50h 50m

Punta Arenas Pres Ibanez

Sat 1/31

1:19 am-10:41 am

2 stops36h 22m

$2,020

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Sat 1/24

1:03 pm-2:05 am

2 stops34h 02m

Punta Arenas Pres Ibanez

Sat 1/31

11:15 pm-10:29 pm

2 stops50h 14m

$2,656

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

  • Most accurate provider: When it comes to deals on Des Moines-Punta Arenas flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Des Moines-Punta Arenas flight deals on Cheapflights vs. Expedia 90-95% of the time. Price accuracy is based on data collected from Des Moines-Punta Arenas flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Punta Arenas flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Punta Arenas flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Punta Arenas

Have a flexible travel schedule? Discover the best time to fly to Punta Arenas from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Punta Arenas. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Punta Arenas?

    LATAM Airlines can get you from Des Moines to Punta Arenas in just under 50h 50m. Your travel time can differ by up to . The distance between Des Moines and Punta Arenas is about 6668 mi.

  • Can I find deals for flights from Des Moines to Punta Arenas that include hotel bookings?

    Yes. In addition to deals on Des Moines to Punta Arenas flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Punta Arenas?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Punta Arenas.

  • Can I find deals for business class flights from Des Moines to Punta Arenas?

    Yes. Cheapflights offers flight deals from Des Moines to Punta Arenas by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Punta Arenas

See prices for flight routes from nearby airports that may be better suited for you.
Cedar Rapids to Santiago flights
Des Moines to Santiago flights
Omaha to Santiago flights
Moline to Santiago flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.