$607+ Cheap flights from Des Moines (DSM) to Portugal
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LIS
Apr 24 — May 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Portugal with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Portugal
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to PortugalExplore the most affordable flight options available from Des Moines to Portugal. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
Explore the most affordable flight options available from Des Moines to Portugal. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:15 am
DSM
- OPO
2 stops23h 25m
United Airlines
Thu 12/106:00 am
OPO
- DSM
2 stops21h 17m
United Airlines
Deal found 3/23![United Airlines logo]()
$738
This KLM deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:23 pm
DSM
- OPO
2 stops17h 07m
KLM
Wed 5/135:55 am
OPO
- DSM
2 stops20h 41m
KLM
Deal found 3/22![KLM logo]()
$806
This KLM deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:31 pm
DSM
- OPO
2 stops14h 54m
Multiple Airlines
Tue 5/126:15 am
OPO
- DSM
2 stops20h 48m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$809
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:16 pm
DSM
- OPO
2 stops23h 44m
Iberia
Sun 5/108:20 am
OPO
- DSM
2 stops21h 29m
Iberia
Deal found 3/20![Iberia logo]()
$810
This Air France deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:23 pm
DSM
- OPO
2 stops17h 02m
Multiple Airlines
Wed 5/135:00 am
OPO
- DSM
2 stops18h 06m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$822
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:56 am
DSM
- OPO
2 stops22h 29m
Delta
Wed 5/135:00 am
OPO
- DSM
2 stops22h 03m
Delta
Deal found 3/21![Delta logo]()
$837
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:25 am
DSM
- OPO
2 stops18h 15m
American Airlines
Tue 5/128:20 am
OPO
- DSM
2 stops17h 13m
American Airlines
Deal found 3/20![American Airlines logo]()
$839
Best flights from Des Moines to PortugalDiscover carefully curated flight deals from Des Moines to Portugal that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
Discover carefully curated flight deals from Des Moines to Portugal that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
This KLM deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:23 pm
DSM
- OPO
2 stops17h 07m
KLM
Wed 5/135:55 am
OPO
- DSM
2 stops20h 41m
KLM
Deal found 3/22![KLM logo]()
$806
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:56 am
DSM
- OPO
2 stops22h 29m
Delta
Wed 5/135:00 am
OPO
- DSM
2 stops22h 03m
Delta
Deal found 3/21![Delta logo]()
$837
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:25 am
DSM
- OPO
2 stops18h 15m
American Airlines
Tue 5/128:20 am
OPO
- DSM
2 stops17h 13m
American Airlines
Deal found 3/20![American Airlines logo]()
$839
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:10 pm
DSM
- OPO
2 stops20h 35m
United Airlines
Sun 4/266:00 am
OPO
- DSM
2 stops22h 43m
United Airlines
Deal found 3/20![United Airlines logo]()
$872
This Air France deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:45 pm
DSM
- OPO
2 stops15h 40m
Multiple Airlines
Sun 4/265:00 am
OPO
- DSM
2 stops16h 41m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$971
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:20 am
DSM
- OPO
2 stops20h 55m
United Airlines
Sat 4/2512:05 pm
OPO
- DSM
2 stops17h 12m
United Airlines
Deal found 3/20![United Airlines logo]()
$872
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:56 am
DSM
- OPO
2 stops22h 29m
Delta
Fri 5/155:00 am
OPO
- DSM
2 stops23h 32m
Delta
Deal found 3/24![Delta logo]()
$937
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:56 am
DSM
- OPO
2 stops22h 29m
Delta
Sat 5/235:00 am
OPO
- DSM
2 stops21h 36m
Delta
Deal found 3/22![Delta logo]()
$947
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:00 am
DSM
- OPO
3 stops17h 00m
United Airlines
Tue 8/1812:15 pm
OPO
- DSM
2 stops27h 56m
United Airlines
Deal found 3/21![United Airlines logo]()
$952
Last-minute flights from Des Moines to PortugalDiscover last-minute flight deals from Des Moines to Portugal. Data last updated March 25, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Portugal. Data last updated March 25, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:30 am
DSM
- OPO
2 stops23h 00m
United Airlines
Sun 4/126:00 am
OPO
- DSM
2 stops23h 17m
United Airlines
Deal found 3/22![United Airlines logo]()
$1,139
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:55 am
DSM
- OPO
2 stops22h 35m
Delta
Sun 4/125:00 am
OPO
- DSM
2 stops21h 45m
Delta
Deal found 3/21![Delta logo]()
$1,306
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:20 am
DSM
- OPO
2 stops20h 55m
United Airlines
Sat 4/2512:05 pm
OPO
- DSM
2 stops17h 12m
United Airlines
Deal found 3/20![United Airlines logo]()
$872
This Air France deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:45 pm
DSM
- OPO
2 stops15h 40m
Multiple Airlines
Sun 4/265:00 am
OPO
- DSM
2 stops16h 41m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$971
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:04 am
DSM
- OPO
3 stops19h 41m
United Airlines
Sun 4/266:00 am
OPO
- DSM
2 stops23h 17m
United Airlines
Deal found 3/21![United Airlines logo]()
$2,141
This Air Canada deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:21 pm
DSM
- OPO
3 stops17h 09m
Air Canada
Sat 4/2510:00 am
OPO
- DSM
3 stops19h 17m
Air Canada
Deal found 3/24![Air Canada logo]()
$2,418
This Air Canada deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:21 pm
DSM
- OPO
3 stops17h 09m
Air Canada
Sun 4/2611:00 am
OPO
- DSM
3 stops18h 17m
Air Canada
Deal found 3/23![Air Canada logo]()
$2,992
One-way flights from Des Moines to PortugalSearch for one-way flight options from Des Moines to Portugal. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
Search for one-way flight options from Des Moines to Portugal. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:04 pm
DSM
- OPO
2 stops20h 21m
Delta
Deal found 3/23![Delta logo]()
$607
This Gotogate deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:05 pm
DSM
- OPO
2 stops22h 20m
Lufthansa
Deal found 3/24![Lufthansa logo]()
$626
This Air Canada deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:30 pm
DSM
- OPO
3 stops17h 00m
Air Canada
Deal found 3/23![Air Canada logo]()
$1,000
This Air Canada deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/93:26 pm
DSM
- OPO
3 stops17h 34m
Air Canada
Deal found 3/24![Air Canada logo]()
$1,488
Find flight deals from Des Moines to Portugal
Keep the following information in mind while searching for Des Moines to Portugal flight deals. Data was last updated March 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $806 (KLM) |
One-way from | $607 (Delta) |
Popular in | June |
Cheapest in | April |
Average price | $864 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Portugal that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Des Moines to Portugal that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Wed 5/6
4:23 pm-3:30 pm
2 stops17h 07m
Porto
Wed 5/13
5:55 am-8:36 pm
2 stops20h 41m
$806
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Wed 5/6
10:56 am-3:25 pm
2 stops22h 29m
Porto
Wed 5/13
5:00 am-9:03 pm
2 stops22h 03m
$837
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Tue 5/5
7:25 am-7:40 am
2 stops18h 15m
Porto
Tue 5/12
8:20 am-7:33 pm
2 stops17h 13m
$839
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Fri 4/17
1:10 pm-3:45 pm
2 stops20h 35m
Porto
Sun 4/26
6:00 am-10:43 pm
2 stops22h 43m
$872
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Fri 4/17
8:20 am-11:15 am
2 stops20h 55m
Porto
Sat 4/25
12:05 pm-11:17 pm
2 stops17h 12m
$872
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Fri 5/8
10:56 am-3:25 pm
2 stops22h 29m
Porto
Fri 5/15
5:00 am-10:32 pm
2 stops23h 32m
$937
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Thu 5/7
10:56 am-3:25 pm
2 stops22h 29m
Porto
Sat 5/23
5:00 am-8:36 pm
2 stops21h 36m
$947
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Tue 8/11
8:00 am-7:00 am
3 stops17h 00m
Porto
Tue 8/18
12:15 pm-10:11 am
2 stops27h 56m
$952
Quickest round-trip
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Fri 4/17
5:45 pm-3:25 pm
2 stops15h 40m
Porto
Sun 4/26
5:00 am-3:41 pm
2 stops16h 41m
$971
Cheapest one-way
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Fri 5/8
1:04 pm-3:25 pm
2 stops20h 21m
$607
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Portugal
Have a flexible travel schedule? Discover the best time to fly to Portugal from Des Moines with our price prediction graph.
DSM-OPO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Portugal
DSM-PT0
DSM-OPO
What is the cheapest month to book a flight from Des Moines to Portugal?
Currently, April is the cheapest month in which you can book a flight from Des Moines to Portugal (average of $528). Flying from Des Moines to Portugal in June is currently the most expensive (average of $1,121). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Portugal
Get insights into the airlines that provide service to Portugal. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portugal. Reviews last updated March 25, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Des Moines to Portugal. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Boarding
7.7
Food
6.6
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Comfort
7.3
Boarding
7.7
Food
6.6
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Comfort
7.3
Boarding
7.7
Food
6.6
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Portugal. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top regions
Alternative routes for Des Moines to Portugal
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Portugal by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Portugal by cabin class
Find flights from Des Moines to Portugal, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Portugal flights
Browse other Des Moines and Portugal flight options. Last updated on March 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Portugal regions
Consider these flights traveling to Portugal regions.
Top 2 airlines flying from Des Moines to Portugal
Discover the top 2 airlines that operate flights from Des Moines to Portugal. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$528 | Average$1,038 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$559 | Average$822 | FlexibilityNo cancel fee | On-time69% |