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Portugal

$451+ Cheap flights from Des Moines (DSM) to Portugal

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LIS
Mar 21 — Mar 281
Sat 3/21
Sat 3/28
1 adult, Economy
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Cheap flight deals from Des Moines to Portugal

Cheapest flights from Des Moines to Portugal
Explore the most affordable flight options available from Des Moines to Portugal. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 19, 2026.

This Expedia deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:01 pm
DSM
-
OPO
2 stops40h 59m
Iberia
Sun 4/264:40 pm
OPO
-
DSM
2 stops37h 09m
Iberia
Deal found 2/16$617
This British Airways deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:16 pm
DSM
-
OPO
2 stops24h 04m
Multiple Airlines
Sat 4/188:40 pm
OPO
-
DSM
2 stops33h 09m
Multiple Airlines
Deal found 2/16$668
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:30 am
DSM
-
OPO
2 stops16h 00m
United Airlines
Sun 3/16:00 am
OPO
-
DSM
2 stops34h 53m
United Airlines
Deal found 2/16$698
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:59 pm
DSM
-
OPO
2 stops32h 46m
United Airlines
Sun 4/266:00 am
OPO
-
DSM
2 stops18h 15m
United Airlines
Deal found 2/18$702
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:04 am
DSM
-
OPO
2 stops25h 41m
United Airlines
Sat 4/2512:05 pm
OPO
-
DSM
2 stops16h 54m
United Airlines
Deal found 2/19$757
This Iberia deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:09 am
DSM
-
OPO
2 stops22h 51m
Iberia
Sat 4/258:40 pm
OPO
-
DSM
2 stops33h 09m
Iberia
Deal found 2/18$868
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:10 pm
DSM
-
OPO
2 stops33h 05m
United Airlines
Tue 5/196:00 am
OPO
-
DSM
2 stops23h 44m
United Airlines
Deal found 2/18$880
This Trip.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/511:33 am
DSM
-
OPO
2 stops17h 07m
Multiple Airlines
Sun 4/124:25 pm
OPO
-
DSM
2 stops31h 20m
Multiple Airlines
Deal found 2/19$892
This Expedia deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:29 pm
DSM
-
OPO
2 stops20h 56m
Multiple Airlines
Sat 4/115:00 am
OPO
-
DSM
2 stops17h 54m
Multiple Airlines
Deal found 2/18$967

Find flight deals from Des Moines to Portugal

Keep the following information in mind while searching for Des Moines to Portugal flight deals. Data was last updated February 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$617
(Expedia)

One-way from

$451
(Mytrip)

Popular in

June

Cheapest in

February

Average price

$545
Provider with most accurate pricing for Des Moines-Lisbon Humberto Delgado flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Lisbon Humberto Delgado flights.
Search Deals
From Des Moines to Portugal
Search Deals
One-way flight from Des Moines to Portugal
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($355 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($52 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Portugal that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
Use the filters below to find and compare flights from Des Moines to Portugal that are best for you.

Fly from

Des Moines

Fly to

Portugal

Route

Depart

Return

Price

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Fri 4/17

5:01 pm-4:00 pm

2 stops40h 59m

Porto

Sun 4/26

4:40 pm-11:49 pm

2 stops37h 09m

$617

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Thu 4/9

2:16 pm-8:20 pm

2 stops24h 04m

Porto

Sat 4/18

8:40 pm-11:49 pm

2 stops33h 09m

$668

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Fri 4/17

6:59 pm-9:45 am

2 stops32h 46m

Porto

Sun 4/26

6:00 am-6:15 pm

2 stops18h 15m

$702

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Fri 4/17

8:04 am-3:45 pm

2 stops25h 41m

Porto

Sat 4/25

12:05 pm-10:59 pm

2 stops16h 54m

$757

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Fri 4/17

11:09 am-4:00 pm

2 stops22h 51m

Porto

Sat 4/25

8:40 pm-7:33 pm

2 stops28h 53m

$868

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Thu 5/14

8:10 pm-11:15 am

2 stops33h 05m

Porto

Tue 5/19

6:00 am-11:44 pm

2 stops23h 44m

$880

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Sun 4/5

11:33 am-10:40 am

2 stops17h 07m

Porto

Sun 4/12

4:25 pm-5:45 pm

2 stops31h 20m

$892

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Sat 4/4

12:29 pm-3:25 pm

2 stops20h 56m

Porto

Sat 4/11

5:00 am-4:54 pm

2 stops17h 54m

$967

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Fri 6/5

8:15 pm-6:50 am

2 stops52h 35m

$451

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Fri 5/8

8:10 pm-10:45 pm

2 stops20h 35m

$490

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/16

Showing 1-10 of 12 results
1
2

Best time to book a flight from Des Moines to Portugal

Have a flexible travel schedule? Discover the best time to fly to Portugal from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Portugal

What is the cheapest month to book a flight from Des Moines to Portugal?

Currently, February is the cheapest month in which you can book a flight from Des Moines to Portugal (average of $545). Flying from Des Moines to Portugal in June is currently the most expensive (average of $1,156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Portugal

Get insights into the airlines that provide service to Portugal. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portugal. Reviews last updated February 19, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Des Moines to Portugal. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,321 reviews

Boarding

7.7

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,321 reviews
United Airlines
7.4
Good
9,321 reviews

Boarding

7.7

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,313 reviews
United Airlines
7.4
Good
9,321 reviews

Boarding

7.7

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Portugal. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Portugal?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Portugal from Des Moines.

  • How long is the flight from Des Moines to Portugal?

    Departing from Des Moines to Portugal will take you 32h 46m. The distance between Des Moines and Portugal is about 4204 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Des Moines to Portugal that include hotel bookings?

    Yes. In addition to deals on Des Moines to Portugal flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Portugal?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Portugal.

  • Can I find deals for business class flights from Des Moines to Portugal?

    Yes. Cheapflights offers flight deals from Des Moines to Portugal by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Portugal?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Portugal (average of $545). Flying from Des Moines to Portugal in June is currently the most expensive (average of $1,156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Des Moines to Portugal

Discover the top 2 airlines that operate flights from Des Moines to Portugal. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$559Average$831FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$874Average$1,045FlexibilityNo cancel feeOn-time71%

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