$478+ Cheap flights from Des Moines (DSM) to Portugal
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LIS
Apr 4 — Apr 111
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to PortugalExplore the most affordable flight options available from Des Moines to Portugal. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.
Explore the most affordable flight options available from Des Moines to Portugal. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.
This Expedia deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Wed 4/228:20 am
OPO
- DSM
2 stops21h 29m
Iberia
Deal found 3/1![Iberia logo]()
$606
This Expedia deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Tue 4/218:20 am
OPO
- DSM
2 stops21h 29m
Iberia
Deal found 2/28![Iberia logo]()
$609
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:45 pm
DSM
- OPO
2 stops15h 40m
Multiple Airlines
Tue 4/215:00 am
OPO
- DSM
2 stops21h 39m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$622
This Iberia deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Mon 4/208:40 pm
OPO
- DSM
2 stops33h 09m
Iberia
Deal found 3/1![Iberia logo]()
$629
This Expedia deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Thu 4/238:20 am
OPO
- DSM
2 stops21h 29m
Iberia
Deal found 3/2![Iberia logo]()
$656
This Expedia deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:45 pm
DSM
- OPO
2 stops15h 40m
Multiple Airlines
Wed 4/225:00 am
OPO
- DSM
2 stops16h 41m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$658
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:16 pm
DSM
- OPO
2 stops15h 29m
American Airlines
Thu 4/238:20 am
OPO
- DSM
2 stops17h 13m
American Airlines
Deal found 3/2![American Airlines logo]()
$660
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:31 pm
DSM
- OPO
2 stops17h 49m
KLM
Wed 5/205:00 am
OPO
- DSM
2 stops18h 06m
KLM
Deal found 3/3![KLM logo]()
$693
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:45 pm
DSM
- OPO
2 stops15h 40m
Air France
Sun 4/264:25 pm
OPO
- DSM
2 stops55h 20m
Air France
Deal found 3/5![Air France logo]()
$696
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:03 pm
DSM
- OPO
2 stops41h 57m
Iberia
Sat 4/254:40 pm
OPO
- DSM
2 stops32h 53m
Iberia
Deal found 3/5![Iberia logo]()
$719
Best flights from Des Moines to PortugalDiscover carefully curated flight deals from Des Moines to Portugal that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 5, 2026.
Discover carefully curated flight deals from Des Moines to Portugal that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 5, 2026.
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:25 am
DSM
- OPO
2 stops18h 15m
American Airlines
Tue 4/218:20 am
OPO
- DSM
2 stops21h 29m
American Airlines
Deal found 2/28![American Airlines logo]()
$609
This Expedia deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Thu 4/238:20 am
OPO
- DSM
2 stops17h 13m
Iberia
Deal found 3/2![Iberia logo]()
$660
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:31 pm
DSM
- OPO
2 stops17h 49m
KLM
Wed 5/205:00 am
OPO
- DSM
2 stops18h 06m
KLM
Deal found 3/3![KLM logo]()
$693
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:45 pm
DSM
- OPO
2 stops15h 40m
Air France
Sun 4/264:25 pm
OPO
- DSM
2 stops55h 20m
Air France
Deal found 3/5![Air France logo]()
$696
This Gotogate deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:01 pm
DSM
- OPO
2 stops56h 39m
Multiple Airlines
Sun 4/2612:25 pm
OPO
- DSM
2 stops41h 24m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$759
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:28 pm
DSM
- OPO
2 stops22h 37m
Delta
Thu 5/215:00 am
OPO
- DSM
2 stops22h 03m
Delta
Deal found 3/1![Delta logo]()
$766
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:16 pm
DSM
- OPO
2 stops32h 29m
United Airlines
Sun 4/266:00 am
OPO
- DSM
2 stops18h 15m
United Airlines
Deal found 3/1![United Airlines logo]()
$823
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:01 pm
DSM
- OPO
2 stops21h 29m
Delta
Sat 4/255:55 am
OPO
- DSM
2 stops17h 07m
Delta
Deal found 3/3![Delta logo]()
$794
This Iberia deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:00 pm
DSM
- OPO
2 stops17h 45m
Iberia
Sat 4/254:40 pm
OPO
- DSM
2 stops32h 53m
Iberia
Deal found 3/4![Iberia logo]()
$815
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:04 am
DSM
- OPO
3 stops19h 41m
United Airlines
Sun 4/266:00 am
OPO
- DSM
2 stops23h 17m
United Airlines
Deal found 3/5![United Airlines logo]()
$857
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:16 pm
DSM
- OPO
2 stops23h 44m
Iberia
Fri 4/248:20 am
OPO
- DSM
2 stops17h 13m
Iberia
Deal found 3/5![Iberia logo]()
$878
Last-minute flights from Des Moines to PortugalDiscover last-minute flight deals from Des Moines to Portugal. Data last updated March 5, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Portugal. Data last updated March 5, 2026 and is based on user searches.
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:45 pm
DSM
- OPO
2 stops15h 40m
Multiple Airlines
Tue 4/215:00 am
OPO
- DSM
2 stops21h 39m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$622
This Iberia deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Mon 4/208:40 pm
OPO
- DSM
2 stops33h 09m
Iberia
Deal found 3/1![Iberia logo]()
$629
This Expedia deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Tue 4/218:20 am
OPO
- DSM
2 stops21h 29m
Iberia
Deal found 2/28![Iberia logo]()
$609
This Expedia deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Wed 4/228:20 am
OPO
- DSM
2 stops21h 29m
Iberia
Deal found 3/1![Iberia logo]()
$606
This Expedia deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:45 pm
DSM
- OPO
2 stops15h 40m
Multiple Airlines
Wed 4/225:00 am
OPO
- DSM
2 stops16h 41m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$658
This Expedia deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:16 pm
DSM
- OPO
2 stops15h 29m
Iberia
Thu 4/238:20 am
OPO
- DSM
2 stops21h 29m
Iberia
Deal found 3/2![Iberia logo]()
$656
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:03 pm
DSM
- OPO
2 stops41h 57m
Iberia
Sat 4/254:40 pm
OPO
- DSM
2 stops32h 53m
Iberia
Deal found 3/5![Iberia logo]()
$719
This Expedia deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:31 pm
DSM
- OPO
2 stops45h 29m
Multiple Airlines
Sat 4/257:00 pm
OPO
- DSM
2 stops31h 39m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$731
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:45 pm
DSM
- OPO
2 stops15h 40m
Air France
Sun 4/264:25 pm
OPO
- DSM
2 stops55h 20m
Air France
Deal found 3/5![Air France logo]()
$696
One-way flights from Des Moines to PortugalSearch for one-way flight options from Des Moines to Portugal. Find affordable one-way fares based on user searches. Data last updated March 5, 2026.
Search for one-way flight options from Des Moines to Portugal. Find affordable one-way fares based on user searches. Data last updated March 5, 2026.
This Air France deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:45 pm
DSM
- OPO
2 stops15h 40m
Air France
Deal found 2/28![Air France logo]()
$478
This Air Canada deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:21 pm
DSM
- OPO
3 stops17h 39m
Air Canada
Deal found 2/28![Air Canada logo]()
$5,190
Find flight deals from Des Moines to Portugal
Keep the following information in mind while searching for Des Moines to Portugal flight deals. Data was last updated March 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $606 (Expedia) |
One-way from | $478 (Air France) |
Popular in | June |
Cheapest in | February |
Average price | $826 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Portugal that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
Use the filters below to find and compare flights from Des Moines to Portugal that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Tue 4/14
7:25 am-7:40 am
2 stops18h 15m
Porto
Tue 4/21
8:20 am-11:49 pm
2 stops21h 29m
$609
Quickest round-trip
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Thu 4/16
2:16 pm-11:45 am
2 stops15h 29m
Porto
Thu 4/23
8:20 am-7:33 pm
2 stops17h 13m
$660
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Wed 5/6
6:31 pm-6:20 pm
2 stops17h 49m
Porto
Wed 5/20
5:00 am-5:06 pm
2 stops18h 06m
$693
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Sun 4/19
5:45 pm-3:25 pm
2 stops15h 40m
Porto
Sun 4/26
4:25 pm-5:45 pm
2 stops55h 20m
$696
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Sun 4/19
5:01 pm-7:40 am
2 stops56h 39m
Porto
Sun 4/26
12:25 pm-11:49 pm
2 stops41h 24m
$759
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Tue 5/12
5:28 pm-10:05 pm
2 stops22h 37m
Porto
Thu 5/21
5:00 am-9:03 pm
2 stops22h 03m
$766
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Sat 4/18
12:01 pm-3:30 pm
2 stops21h 29m
Porto
Sat 4/25
5:55 am-5:02 pm
2 stops17h 07m
$794
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Sat 4/18
12:00 pm-11:45 am
2 stops17h 45m
Porto
Sat 4/25
4:40 pm-7:33 pm
2 stops32h 53m
$815
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Fri 4/17
7:16 pm-9:45 am
2 stops32h 29m
Porto
Sun 4/26
6:00 am-6:15 pm
2 stops18h 15m
$823
Des MoinesPorto
DSM - OPO
DSMOPO
Des Moines
Sun 4/19
8:04 am-9:45 am
3 stops19h 41m
Porto
Sun 4/26
6:00 am-11:17 pm
2 stops23h 17m
$857
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Portugal
Have a flexible travel schedule? Discover the best time to fly to Portugal from Des Moines with our price prediction graph.
DSM-OPO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Portugal
DSM-PT0
DSM-OPO
What is the cheapest month to book a flight from Des Moines to Portugal?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Portugal (average of $545). Flying from Des Moines to Portugal in June is currently the most expensive (average of $1,156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Portugal
Get insights into the airlines that provide service to Portugal. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portugal. Reviews last updated March 5, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Des Moines to Portugal. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Overall
7.4
Boarding
7.7
Food
6.6
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Crew
8.1
Overall
7.4
Boarding
7.7
Food
6.6
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Crew
8.1
Overall
7.4
Boarding
7.7
Food
6.6
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Portugal. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Portugal
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Complete your trip
Complete your trip to Portugal by adding a car rental and/or hotel reservation to your travel itinerary.
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Des Moines and Portugal flights
Browse other Des Moines and Portugal flight options. Last updated on March 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Portugal regions
Consider these flights traveling to Portugal regions.
Top 2 airlines flying from Des Moines to Portugal
Discover the top 2 airlines that operate flights from Des Moines to Portugal. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$559 | Average$822 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$874 | Average$1,075 | FlexibilityNo cancel fee | On-time71% |