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$410+ Cheap flights from Des Moines (DSM) to Portugal

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LIS
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from Des Moines to Portugal

Keep the following information in mind while searching for Des Moines to Portugal flight deals. Data was last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$428
(Ticket)

One-way from

$410
(Flightnetwork)

Popular in

May

Cheapest in

November

Average price

$644
Provider with most accurate pricing for Des Moines-Lisbon Humberto Delgado flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Lisbon Humberto Delgado flights.
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From Des Moines to Portugal
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One-way flight from Des Moines to Portugal
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Highest demand for flights based on searches. 28% potential increase in price ($405 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($54 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Des Moines to Portugal

Best flights from Des Moines to Portugal
Discover carefully curated flight deals from Des Moines to Portugal that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 26, 2025.

This Ticket deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/811:30 amDSM - OPO
2 stops18h 10mLufthansa
Thu 1/156:00 amOPO - DSM
2 stops21h 50mLufthansa
Deal found 11/23$428
This Billigflug deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/88:00 amDSM - OPO
2 stops21h 10mMultiple Airlines
Thu 1/156:00 amOPO - DSM
2 stops22h 30mMultiple Airlines
Deal found 11/25$464
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3010:21 amDSM - OPO
2 stops18h 09mDelta
Tue 2/36:05 amOPO - DSM
2 stops33h 36mDelta
Deal found 11/23$491
This Ticket deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/96:48 pmDSM - OPO
2 stops21h 37mLufthansa
Fri 1/166:00 amOPO - DSM
2 stops21h 50mLufthansa
Deal found 11/25$465

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Portugal that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Des Moines to Portugal that are best for you.

Fly from

Des Moines

Fly to

Portugal

Route

Depart

Return

Price

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Thu 1/8

11:30 am-11:40 am

2 stops18h 10m

Porto

Thu 1/15

6:00 am-9:50 pm

2 stops21h 50m

$428

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Thu 1/8

8:00 am-11:10 am

2 stops21h 10m

Porto

Thu 1/15

6:00 am-10:30 pm

2 stops22h 30m

$464

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Fri 1/9

6:48 pm-10:25 pm

2 stops21h 37m

Porto

Fri 1/16

6:00 am-9:50 pm

2 stops21h 50m

$465

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Fri 1/30

10:21 am-10:30 am

2 stops18h 09m

Porto

Tue 2/3

6:05 am-9:41 am

2 stops33h 36m

$491

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Thu 1/8

6:48 pm-10:25 pm

2 stops21h 37m

$410

Des MoinesPorto

DSM - OPO

DSMOPO

Des Moines

Thu 1/8

8:00 am-2:45 pm

3 stops48h 45m

$5,197

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Best time to book a flight from Des Moines to Portugal

Have a flexible travel schedule? Discover the best time to fly to Portugal from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Portugal

What is the cheapest month to book a flight from Des Moines to Portugal?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Portugal (average of $552). Flying from Des Moines to Portugal in June is currently the most expensive (average of $1,173). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Portugal

Get insights into the airlines that provide service to Portugal. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portugal. Reviews last updated November 26, 2025.
Read reviews from past customers who have flown United Airlines, American Airlines, and British Airways from Des Moines to Portugal. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,046 reviews

Comfort

7.3

Food

6.6

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,046 reviews
United Airlines
7.4
Good
9,046 reviews

Comfort

7.3

Food

6.6

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,038 reviews
United Airlines
7.4
Good
9,046 reviews

Comfort

7.3

Food

6.6

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
British Airways
6.7
Okay
7,539 reviews
United Airlines
7.4
Good
9,046 reviews

Comfort

7.3

Food

6.6

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Portugal. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Portugal?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Portugal from Des Moines.

  • How long is the flight from Des Moines to Portugal?

    Departing from Des Moines to Portugal will take you 18h 10m. The distance between Des Moines and Portugal is about 4204 mi.

  • Can I find deals for flights from Des Moines to Portugal that include hotel bookings?

    Yes. In addition to deals on Des Moines to Portugal flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Portugal?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Portugal.

  • Can I find deals for business class flights from Des Moines to Portugal?

    Yes. Cheapflights offers flight deals from Des Moines to Portugal by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Portugal?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Portugal (average of $552). Flying from Des Moines to Portugal in June is currently the most expensive (average of $1,173). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Des Moines to Portugal

Discover the top 3 airlines that operate flights from Des Moines to Portugal. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$559Average$890FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$631Average$842FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$693Average$1,038FlexibilityNo cancel feeOn-time71%

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