
Keep the following information in mind while searching for South Carolina to Portland flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (SmartFares) |
One-way from | $160 (Delta) |
Popular in | April |
Cheapest in | February |
Average price | $473 |
Fly from
Fly to
Route
Depart
Return
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Tue 12/8
2:18 pm-7:17 pm
1 stop7h 59m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Tue 12/8
3:25 pm-11:25 pm
2 stops11h 00m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
CharlestonPortland
CHS Charleston - PDX Portland
CHSPDX
Charleston
Wed 12/16
6:00 am-6:07 pm
2 stops15h 07m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Tue 12/8
12:21 pm-8:06 pm
1 stop10h 45m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Wed 12/23
10:46 am-6:21 pm
1 stop10h 35m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Wed 12/16
2:18 pm-9:58 pm
1 stop10h 40m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
CharlestonPortland
CHS Charleston - PDX Portland
CHSPDX
Charleston
Wed 12/16
6:40 am-12:09 pm
3 stops32h 29m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
CharlestonPortland
CHS Charleston - PDX Portland
CHSPDX
Charleston
Wed 11/11
6:34 am-1:14 pm
1 stop9h 40m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
CharlestonPortland
CHS Charleston - PDX Portland
CHSPDX
Charleston
Sun 12/20
5:15 am-11:46 am
1 stop9h 31m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Fri 4/23
3:20 pm-10:18 pm
1 stop9h 58m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Everything you need to know about your flight from South Carolina to Portland
Find useful and relevant information for your journey from South Carolina to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$474 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$483 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$344 | Average$496 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$376 | Average$507 | FlexibilityNo cancel fee | On-time63% |