
Keep the following information in mind while searching for South Carolina to Portland flight deals. Data was last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $346 (SmartFares) |
One-way from | $185 (Delta) |
Popular in | April |
Cheapest in | February |
Average price | $524 |
Fly from
Fly to
Route
Depart
Return
GreenvillePortland
GSP Greenville - PDX Portland
GSPPDX
Greenville
Tue 12/1
5:40 am-10:49 am
1 stop8h 09m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Tue 12/8
12:21 pm-8:06 pm
1 stop10h 45m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
GreenvillePortland
GSP Greenville - PDX Portland
GSPPDX
Greenville
Fri 12/11
5:40 am-10:48 am
1 stop8h 08m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Wed 12/16
2:18 pm-9:58 pm
1 stop10h 40m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Myrtle BeachPortland
MYR Myrtle Beach Intl - PDX Portland
MYRPDX
Myrtle Beach Intl
Tue 12/8
3:25 pm-11:25 pm
2 stops11h 00m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
CharlestonPortland
CHS Charleston - PDX Portland
CHSPDX
Charleston
Mon 11/23
3:27 pm-10:28 am
2 stops22h 01m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
CharlestonPortland
CHS Charleston - PDX Portland
CHSPDX
Charleston
Mon 11/23
5:20 am-10:41 am
1 stop8h 21m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
GreenvillePortland
GSP Greenville - PDX Portland
GSPPDX
Greenville
Fri 12/11
1:00 pm-10:45 pm
2 stops12h 45m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
CharlestonPortland
CHS Charleston - PDX Portland
CHSPDX
Charleston
Wed 12/30
6:44 pm-12:09 am
1 stop8h 25m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
GreenvillePortland
GSP Greenville - PDX Portland
GSPPDX
Greenville
Tue 12/1
7:05 am-4:45 pm
2 stops12h 40m
Portland
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
Everything you need to know about your flight from South Carolina to Portland
Find useful and relevant information for your journey from South Carolina to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$474 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$344 | Average$494 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$376 | Average$507 | FlexibilityNo cancel fee | On-time63% |