Portland

$160+ Cheap flights from South Carolina to Portland (PDX)

CHS — PDX
Nov 29 — Dec 61
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Cheap flight deals from South Carolina to Portland

Cheapest flights from South Carolina to Portland

Sat 12/55:40 am -
1 stop8h 09m
Thu 12/1711:17 pm -
1 stop8h 10m
Deal found 10/28$299
Tue 11/245:40 am -
1 stop8h 01m
Tue 12/16:50 am -
1 stop8h 30m
Deal found 10/27$319
Wed 11/254:29 pm -
1 stop7h 44m
Wed 12/27:25 pm -
2 stops11h 27m
Deal found 10/28$324
Fri 12/45:40 am -
1 stop8h 08m
Thu 12/1711:17 pm -
1 stop8h 10m
Deal found 10/29$339
Fri 12/42:04 pm -
2 stops11h 41m
Wed 12/910:43 am -
1 stop7h 16m
Deal found 10/27$344
Fri 12/42:50 pm -
2 stops10h 30m
Wed 12/96:00 am -
2 stops10h 55m
Deal found 10/27$349
Sat 12/1211:36 am -
1 stop11h 11m
Tue 1/59:55 pm -
1 stop9h 38m
Deal found 10/28$352
Fri 12/412:18 pm -
1 stop9h 59m
Sat 12/1910:25 pm -
1 stop7h 59m
Deal found 10/29$372
Wed 11/2512:17 pm -
1 stop11h 12m
Wed 12/210:00 pm -
1 stop7h 34m
Deal found 10/28$375
Wed 11/252:52 pm -
2 stops11h 17m
Wed 12/25:00 am -
1 stop7h 12m
Deal found 10/28$380
Sat 12/1212:10 pm -
1 stop9h 33m
Tue 12/157:25 pm -
2 stops12h 38m
Deal found 10/30$384
Fri 12/45:10 pm -
1 stop9h 39m
Sun 12/65:00 am -
1 stop8h 28m
Deal found 10/25$399

Find flight deals from South Carolina to Portland

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$299
(SmartFares)

One-way from

$160
(Delta)

Popular in

April

Cheapest in

February

Average price

$473
Provider with most accurate pricing for Myrtle Beach Intl-Portland flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Portland flights.
From South Carolina to Portland
One-way flight from South Carolina to Portland
Highest demand for flights based on searches. 16% potential increase in price ($113 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in October 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from South Carolina to Portland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPortland

MYR Myrtle Beach Intl - PDX Portland

MYRPDX

Myrtle Beach Intl

Tue 12/8

2:18 pm-7:17 pm

1 stop7h 59m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$160

Myrtle BeachPortland

MYR Myrtle Beach Intl - PDX Portland

MYRPDX

Myrtle Beach Intl

Tue 12/8

3:25 pm-11:25 pm

2 stops11h 00m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$165

CharlestonPortland

CHS Charleston - PDX Portland

CHSPDX

Charleston

Wed 12/16

6:00 am-6:07 pm

2 stops15h 07m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$193

Myrtle BeachPortland

MYR Myrtle Beach Intl - PDX Portland

MYRPDX

Myrtle Beach Intl

Tue 12/8

12:21 pm-8:06 pm

1 stop10h 45m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$193

Myrtle BeachPortland

MYR Myrtle Beach Intl - PDX Portland

MYRPDX

Myrtle Beach Intl

Wed 12/23

10:46 am-6:21 pm

1 stop10h 35m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$193

Myrtle BeachPortland

MYR Myrtle Beach Intl - PDX Portland

MYRPDX

Myrtle Beach Intl

Wed 12/16

2:18 pm-9:58 pm

1 stop10h 40m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$193

CharlestonPortland

CHS Charleston - PDX Portland

CHSPDX

Charleston

Wed 12/16

6:40 am-12:09 pm

3 stops32h 29m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$222

CharlestonPortland

CHS Charleston - PDX Portland

CHSPDX

Charleston

Wed 11/11

6:34 am-1:14 pm

1 stop9h 40m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$222

CharlestonPortland

CHS Charleston - PDX Portland

CHSPDX

Charleston

Sun 12/20

5:15 am-11:46 am

1 stop9h 31m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$248

Myrtle BeachPortland

MYR Myrtle Beach Intl - PDX Portland

MYRPDX

Myrtle Beach Intl

Fri 4/23

3:20 pm-10:18 pm

1 stop9h 58m

Portland

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 58 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from South Carolina with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Portland

What is the cheapest month to book a flight from South Carolina to Portland?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Portland (average of $438). Flying from South Carolina to Portland in December is currently the most expensive (average of $643). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from South Carolina to Portland?

To ensure you get the cheapest price possible for a flight from South Carolina to Portland, you should look to book at least 74 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Related info for your journey

  • What airport do you fly into for flights to Portland from South Carolina?

    For a flight from South Carolina to Portland, you will be flying into Portland. Portland (PDX) is just 6.0 mi from the center of the city.

  • How long is the flight from South Carolina to Portland?

    There are many flights that can get you from South Carolina to Portland in 7h 47m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. The distance between South Carolina and Portland is about 2225 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to Portland one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $114. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from South Carolina to Portland for a low price.

  • What are the most popular routes from South Carolina to Portland?

  • Can I find deals for flights from South Carolina to Portland that include hotel bookings?

    Yes. In addition to deals on South Carolina to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Portland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Portland.

  • Can I find deals for business class flights from South Carolina to Portland?

    Yes. Cheapflights offers flight deals from South Carolina to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Portland?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Portland (average of $438). Flying from South Carolina to Portland in December is currently the most expensive (average of $643). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
Beaverton
Seaside
Durham
Cannon Beach
Longview
Lake Oswego
Lincoln City
Vancouver
Kelso
Troutdale
Clackamas
McMinnville
The Dalles
Wilsonville
Stevenson
Hillsboro
Tillamook
Astoria

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Carolina to Portland

Top 4 airlines flying from South Carolina to Portland

AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$474FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$328Average$483FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$344Average$496FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$376Average$507FlexibilityNo cancel feeOn-time63%

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