$124+ Cheap flights from Portland (PDX) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Portland to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:00 pm -
1 stop8h 47m
Sat 12/512:19 pm -
1 stop10h 27m
Deal found 10/22![American Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
1 stop7h 30m
Wed 12/161:25 pm -
2 stops11h 55m
Deal found 10/22![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:10 pm -
1 stop7h 25m
Sat 11/142:00 pm -
1 stop8h 14m
Deal found 10/22![Delta logo]()
$265
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:30 pm -
1 stop7h 00m
Sat 11/141:56 pm -
2 stops10h 32m
Deal found 10/22![United Airlines logo]()
$270
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
2 stops9h 10m
Wed 12/92:50 pm -
2 stops10h 30m
Deal found 10/22![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:50 pm -
1 stop8h 36m
Tue 11/1712:02 pm -
1 stop10h 52m
Deal found 10/22![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:10 pm -
1 stop8h 11m
Tue 11/1711:27 am -
2 stops14h 00m
Deal found 10/21![United Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:40 pm -
2 stops15h 41m
Tue 11/1711:27 am -
2 stops14h 00m
Deal found 10/22![United Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:25 pm -
2 stops12h 38m
Sat 12/56:00 am -
1 stop8h 41m
Deal found 10/22![United Airlines logo]()
$294
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:24 pm -
1 stop6h 35m
Sun 11/155:20 am -
1 stop8h 21m
Deal found 10/21![Delta logo]()
$296
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:50 pm -
1 stop9h 32m
Tue 11/177:51 am -
1 stop8h 53m
Deal found 10/22![American Airlines logo]()
$301
This Travelocity deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:30 pm -
2 stops10h 56m
Thu 12/36:20 pm -
1 stop8h 35m
Deal found 10/21![Alaska Airlines logo]()
$302
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:10 pm -
1 stop8h 11m
Tue 11/1711:27 am -
2 stops14h 00m
Deal found 10/21![United Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:24 pm -
1 stop6h 35m
Sun 11/155:20 am -
1 stop8h 21m
Deal found 10/21![Delta logo]()
$296
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 am -
2 stops9h 55m
Mon 12/73:25 pm -
2 stops11h 00m
Deal found 10/22![Southwest logo]()
$331
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:30 pm -
1 stop7h 28m
Sat 12/125:20 pm -
1 stop9h 29m
Deal found 10/25![American Airlines logo]()
$399
This Alaska Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:59 pm -
1 stop15h 56m
Sat 11/75:58 pm -
1 stop8h 02m
Deal found 10/24![Alaska Airlines logo]()
$500
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:26 pm -
2 stops11h 55m
Tue 11/1711:27 am -
3 stops12h 46m
Deal found 10/21![United Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:00 pm -
1 stop9h 33m
Sat 12/127:20 am -
1 stop9h 21m
Deal found 10/25![American Airlines logo]()
$418
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:45 am -
1 stop7h 34m
Wed 11/253:47 pm -
1 stop9h 10m
Deal found 10/21![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
1 stop6h 56m
Thu 11/195:12 pm -
1 stop9h 03m
Deal found 10/24![United Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:55 am -
2 stops8h 20m
Thu 11/192:50 pm -
2 stops11h 35m
Deal found 10/24![Southwest logo]()
$429
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:17 pm -
1 stop8h 24m
Sat 12/124:04 pm -
1 stop8h 54m
Deal found 10/22![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:30 pm -
1 stop7h 00m
Sat 11/146:00 am -
3 stops15h 24m
Deal found 10/22![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:55 am -
2 stops8h 15m
Wed 11/116:35 am -
2 stops9h 35m
Deal found 10/22![Southwest logo]()
$462
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:20 pm -
1 stop7h 51m
Wed 11/255:10 pm -
1 stop7h 47m
Deal found 10/21![Delta logo]()
$426
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:13 pm -
2 stops11h 57m
Wed 12/165:10 pm -
1 stop9h 39m
Deal found 10/23![American Airlines logo]()
$483
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 am -
2 stops12h 10m
Sat 11/146:40 am -
2 stops10h 40m
Deal found 10/25![Southwest logo]()
$462
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:20 pm -
1 stop7h 51m
Wed 11/255:10 pm -
1 stop7h 47m
Deal found 10/21![Delta logo]()
$436
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:26 pm -
2 stops11h 25m
Tue 11/176:20 am -
3 stops15h 00m
Deal found 10/22![United Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:00 am -
2 stops14h 59m
Wed 11/252:35 pm -
1 stop9h 25m
Deal found 10/21![American Airlines logo]()
$506
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:50 pm -
2 stops17h 05m
Sat 12/1210:35 am -
2 stops12h 30m
Deal found 10/23![Southwest logo]()
$476
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:00 am -
2 stops10h 06m
Sat 11/144:15 pm -
1 stop8h 13m
Deal found 10/25![United Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:20 pm -
1 stop8h 20m
Sun 11/156:00 am -
1 stop7h 41m
Deal found 10/23![Delta logo]()
$449
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:00 am -
1 stop8h 30m
Sun 11/225:10 pm -
1 stop10h 06m
Deal found 10/25![American Airlines logo]()
$542
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:30 pm -
2 stops9h 55m
Tue 12/12:50 pm -
2 stops10h 30m
Deal found 10/25![Southwest logo]()
$495
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:10 pm -
1 stop7h 11m
Thu 11/266:00 am -
1 stop7h 41m
Deal found 10/21![Delta logo]()
$459
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:26 pm -
2 stops11h 33m
Tue 11/1010:37 am -
1 stop7h 46m
Deal found 10/22![United Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:00 pm -
1 stop7h 35m
Tue 12/292:25 pm -
1 stop10h 48m
Deal found 10/25![American Airlines logo]()
$576
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:30 pm -
1 stop7h 00m
Wed 11/254:29 pm -
1 stop9h 40m
Deal found 10/21![United Airlines logo]()
$489
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:51 am -
1 stop8h 47m
Thu 11/269:15 am -
1 stop9h 50m
Deal found 10/21![Delta logo]()
$497
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:25 am -
1 stop14h 00m
Sun 1/34:55 pm -
2 stops11h 20m
Deal found 10/26![Southwest logo]()
$584
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated October 26, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:30 pm -
1 stop8h 51m
Wed 11/112:52 pm -
1 stop8h 23m
Deal found 10/22![United Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:50 pm -
1 stop8h 36m
Tue 11/1712:02 pm -
1 stop10h 52m
Deal found 10/22![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:40 pm -
2 stops15h 41m
Tue 11/1711:27 am -
2 stops14h 00m
Deal found 10/22![United Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:26 pm -
2 stops11h 55m
Tue 11/1711:27 am -
2 stops14h 48m
Deal found 10/21![United Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:10 pm -
1 stop8h 11m
Tue 11/1711:27 am -
2 stops14h 00m
Deal found 10/21![United Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:24 pm -
1 stop6h 35m
Sun 11/155:20 am -
1 stop8h 21m
Deal found 10/21![Delta logo]()
$296
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:10 pm -
1 stop7h 25m
Sat 11/142:00 pm -
1 stop8h 14m
Deal found 10/22![Delta logo]()
$265
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:30 pm -
1 stop7h 00m
Sat 11/141:56 pm -
2 stops10h 32m
Deal found 10/22![United Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:50 pm -
1 stop9h 32m
Tue 11/177:51 am -
1 stop8h 53m
Deal found 10/22![American Airlines logo]()
$301
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:30 pm -
1 stop7h 00m
Thu 11/262:51 pm -
1 stop8h 24m
Deal found 10/21![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:11 pm -
1 stop9h 15m
Thu 11/267:00 am -
1 stop9h 39m
Deal found 10/22![American Airlines logo]()
$371
This Expedia deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:30 pm -
1 stop16h 47m
Thu 12/36:20 pm -
1 stop8h 35m
Deal found 10/21![Alaska Airlines logo]()
$247
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:10 am -
1 stop10h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$124
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:25 pm -
2 stops12h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:10 pm -
3 stops26h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$164
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1311:30 pm -
2 stops10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Southwest logo]()
$178
This Alaska Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:59 pm -
2 stops11h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Alaska Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:11 pm -
1 stop9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$190
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:10 pm -
1 stop7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Delta logo]()
$193
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:15 pm -
2 stops11h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$198
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:30 pm -
1 stop7h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![United Airlines logo]()
$199
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:42 pm -
1 stop7h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:51 pm -
3 stops46h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:02 pm -
3 stops40h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$216
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $247 (Delta) |
One-way from | $124 (Delta) |
Popular in | November |
Cheapest in | January |
Average price | $508 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Tue 12/8
7:10 am-8:19 pm
1 stop10h 09m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$124
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Mon 12/7
11:17 pm-12:21 pm
1 stop10h 04m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$124
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Mon 12/7
7:25 pm-11:03 am
2 stops12h 38m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$129
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Tue 12/8
5:10 pm-10:55 pm
3 stops26h 45m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$164
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Sun 12/13
11:10 pm-10:15 am
1 stop8h 05m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$173
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Sun 12/13
11:30 pm-12:45 pm
2 stops10h 15m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$178
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Sat 11/21
9:30 pm-11:26 am
2 stops10h 56m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$179
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Sat 11/21
11:11 pm-11:26 am
1 stop9h 15m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$190
PortlandGreenville
PDX Portland - GSP Greenville
PDXGSP
Portland
Wed 11/18
11:30 pm-9:30 am
1 stop7h 00m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$193
Quickest round-trip
PortlandGreenville
PDX Portland - GSP Greenville
PDXGSP
Portland
Wed 12/9
7:00 am-4:53 pm
1 stop6h 53m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$193
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PDX-MYR
PDX-CHS
PDX-CAE
PDX-GSP
PDX-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PDX-USSC
PDX-MYR
PDX-CHS
PDX-CAE
PDX-GSP
What is the cheapest month to book a flight from Portland to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Portland to South Carolina (average of $403). Flying from Portland to South Carolina in March is currently the most expensive (average of $641). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to South Carolina?
Airfare is below average for this route at the moment.
Portland to South Carolina flights typically cost between $404 and $665 in January.The cheapest round-trip price found within the last 5 days was $247 on Delta (Jan 26-Feb 2).
How far ahead should I book a flight from Portland to South Carolina?
Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 26, 2026.
See what other customers who have flown with Alaska Airlines,Southwest, andDelta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.0
Food
7.0
Overall
7.9
Crew
8.5
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentAnonymous,Nov 2025
PDX - BNA
Boarding
8.1
Entertainment
7.0
Food
7.0
Overall
7.9
Crew
8.5
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentAnonymous,Nov 2025
PDX - BNA
Boarding
8.1
Entertainment
7.0
Food
7.0
Overall
7.9
Crew
8.5
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentAnonymous,Nov 2025
PDX - BNA
Boarding
8.1
Entertainment
7.0
Food
7.0
Overall
7.9
Crew
8.5
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentAnonymous,Nov 2025
PDX - BNA
Boarding
8.1
Entertainment
7.0
Food
7.0
Overall
7.9
Crew
8.5
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentAnonymous,Nov 2025
PDX - BNA
Boarding
8.1
Entertainment
7.0
Food
7.0
Overall
7.9
Crew
8.5
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentAnonymous,Nov 2025
PDX - BNA
Related info for your journey
Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to South Carolina
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Complete your trip
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Search flights from Portland to South Carolina by cabin class
Find flights from Portland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on October 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$208 | Average$483 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$266 | Average$505 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$298 | Average$476 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$304 | Average$509 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$393 | Average$571 | FlexibilityNo cancel fee | On-time63% |