South Carolina

$92+ Cheap flights from Portland (PDX) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
mag 27 — giu 31
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Cheap flight deals from Portland to South Carolina

Cheapest flights from Portland to South Carolina
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on aprile 27, 2026.

This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 6/311:20 am
PDX
-
CHS
1 stop8h 40m
American Airlines
mar 6/97:19 pm
CHS
-
PDX
1 stop8h 31m
American Airlines
Deal found 4/23$265
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 9/1511:55 am
PDX
-
GSP
1 stop7h 05m
Delta
mar 9/226:45 am
GSP
-
PDX
1 stop6h 52m
Delta
Deal found 4/23$269
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 8/2911:59 pm
PDX
-
CHS
1 stop9h 41m
American Airlines
mar 9/13:41 pm
CHS
-
PDX
1 stop10h 26m
American Airlines
Deal found 4/23$270
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/29:39 pm
PDX
-
GSP
1 stop8h 25m
Delta
mer 6/31:09 pm
GSP
-
PDX
2 stops11h 53m
Delta
Deal found 4/24$274
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/22:06 pm
PDX
-
CHS
1 stop6h 53m
Delta
sab 6/66:00 am
CHS
-
PDX
1 stop8h 46m
Delta
Deal found 4/23$275
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 9/1511:30 pm
PDX
-
GSP
2 stops9h 55m
Southwest
mar 9/227:00 am
GSP
-
PDX
2 stops11h 00m
Southwest
Deal found 4/23$281
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/25:07 am
PDX
-
GSP
1 stop8h 28m
American Airlines
mer 6/37:54 pm
GSP
-
PDX
1 stop7h 56m
American Airlines
Deal found 4/23$285
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/2912:34 pm
PDX
-
CHS
1 stop8h 22m
American Airlines
mar 6/96:18 pm
CHS
-
PDX
1 stop8h 41m
American Airlines
Deal found 4/22$294
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 6/19:39 pm
PDX
-
CHS
1 stop8h 59m
Delta
sab 6/66:00 am
CHS
-
PDX
1 stop8h 46m
Delta
Deal found 4/23$295
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 9/2111:30 pm
PDX
-
CHS
2 stops10h 05m
Southwest
mer 9/301:15 pm
CHS
-
PDX
1 stop7h 30m
Southwest
Deal found 4/23$299
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 6/111:12 pm
PDX
-
GSP
1 stop8h 43m
Delta
mer 6/1011:38 am
GSP
-
PDX
2 stops10h 46m
Delta
Deal found 4/23$302
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/282:44 pm
PDX
-
MYR
1 stop21h 34m
Allegiant Air
sab 6/69:59 pm
MYR
-
PDX
1 stop18h 49m
Allegiant Air
Deal found 4/26$307

Find flight deals from Portland to South Carolina

Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated aprile 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$265
(American Airlines)

One-way from

$92
(CheapOair)

Popular in

April

Cheapest in

January

Average price

$546
Provider with most accurate pricing for Portland-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Portland-Myrtle Beach Intl flights.
From Portland to South Carolina
One-way flight from Portland to South Carolina
Highest demand for flights based on searches. 7% potential increase in price ($39 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated aprile 27, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandGreenville

PDX - GSP

PDXGSP

Portland

mar 6/2

9:39 pm-9:04 am

1 stop8h 25m

Greenville

mer 6/3

1:09 pm-10:02 pm

2 stops11h 53m

$274

PortlandCharleston

PDX - CHS

PDXCHS

Portland

ven 6/5

11:12 pm-12:19 pm

1 stop10h 07m

Charleston

lun 6/8

1:11 pm-6:49 pm

1 stop8h 38m

$319

PortlandCharleston

PDX - CHS

PDXCHS

Portland

ven 5/29

6:50 pm-8:51 am

2 stops11h 01m

Charleston

mar 6/9

6:30 pm-11:53 pm

1 stop8h 23m

$336

PortlandCharleston

PDX - CHS

PDXCHS

Portland

ven 5/29

8:05 am-8:50 pm

2 stops9h 45m

Charleston

mar 6/9

4:15 pm-10:35 pm

2 stops9h 20m

$373

PortlandCharleston

PDX - CHS

PDXCHS

Portland

mar 7/14

11:40 pm-10:08 am

1 stop7h 28m

Charleston

mer 7/22

11:31 am-6:47 pm

1 stop10h 16m

$377

PortlandCharleston

PDX - CHS

PDXCHS

Portland

mer 6/24

11:40 pm-10:08 am

1 stop7h 28m

Charleston

lun 6/29

4:16 pm-11:03 pm

1 stop9h 47m

$386

PortlandCharleston

PDX - CHS

PDXCHS

Portland

gio 7/9

9:20 pm-9:55 am

1 stop9h 35m

Charleston

mar 7/14

2:10 pm-10:35 pm

2 stops11h 25m

$391

PortlandColumbia

PDX - CAE

PDXCAE

Portland

dom 5/17

9:39 pm-9:15 am

1 stop8h 36m

Columbia Metropolitan

dom 5/24

5:40 am-12:26 pm

2 stops9h 46m

$394

PortlandCharleston

PDX - CHS

PDXCHS

Portland

lun 6/1

10:40 pm-10:08 am

1 stop8h 28m

Charleston

lun 6/8

6:30 pm-11:53 pm

1 stop8h 23m

$395

PortlandMyrtle Beach

PDX - MYR

PDXMYR

Portland

sab 5/30

12:35 pm-9:50 am

2 stops18h 15m

Myrtle Beach Intl

sab 6/6

9:59 pm-1:48 pm

1 stop18h 49m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Portland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to South Carolina

How far ahead should I book a flight from Portland to South Carolina?

Booking 45 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Portland to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Portland to South Carolina (average of $129). Flying from Portland to South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Portland to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated aprile 27, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Portland to South Carolina?

    Portland (PDX), located 6.0 mi from the city center, is the airport you fly out of when you book flights from Portland to South Carolina.

  • How long is the flight from Portland to South Carolina?

    There are many flights that can get you from Portland to South Carolina in 8h 25m. Fly via Delta, United Airlines, or Southwest to get the fastest option. The distance between Portland and South Carolina is about 2225 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland to South Carolina one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $127. However, be on the lookout for offers from Delta and Alaska Airlines, as they are both options that can get you from Portland to South Carolina for a low price.

  • What are the most popular routes from Portland to South Carolina?

  • Can I find deals for flights from Portland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Portland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to South Carolina.

  • Can I find deals for business class flights from Portland to South Carolina?

    Yes. Cheapflights offers flight deals from Portland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Portland to South Carolina (average of $129). Flying from Portland to South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Portland to South Carolina

Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated aprile 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$452FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$276Average$452FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$294Average$523FlexibilityNo cancel feeOn-time71%
Alaska AirlinesCheapest$298Average$602FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$329Average$540FlexibilityNo cancel feeOn-time63%

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