$147+ Cheap flights from Portland (PDX) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from Portland to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to South Carolina
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Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:15 pm
PDX
- CHS
1 stop10h 57m
Delta
Sat 11/78:50 am
CHS
- PDX
1 stop7h 48m
Delta
Deal found 7/28![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:25 am
PDX
- CHS
1 stop7h 45m
United Airlines
Sat 9/57:00 am
CHS
- PDX
2 stops11h 05m
United Airlines
Deal found 7/24![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:30 pm
PDX
- CHS
2 stops13h 40m
Southwest
Sat 9/1211:00 am
CHS
- PDX
2 stops10h 30m
Southwest
Deal found 7/24![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:02 pm
PDX
- CAE
1 stop7h 41m
United Airlines
Wed 9/91:48 pm
CAE
- PDX
1 stop11h 15m
United Airlines
Deal found 7/28![United Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:44 pm
PDX
- MYR
1 stop7h 51m
American Airlines
Tue 9/155:01 pm
MYR
- PDX
1 stop9h 22m
American Airlines
Deal found 7/26![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:27 am
PDX
- GSP
1 stop7h 11m
American Airlines
Wed 9/95:24 pm
GSP
- PDX
1 stop8h 59m
American Airlines
Deal found 7/26![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:45 am
PDX
- CHS
2 stops8h 35m
Southwest
Sat 9/511:00 am
CHS
- PDX
2 stops10h 30m
Southwest
Deal found 7/24![Southwest logo]()
$369
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:58 am
PDX
- CAE
1 stop7h 29m
American Airlines
Wed 9/97:00 am
CAE
- PDX
1 stop9h 17m
American Airlines
Deal found 7/26![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am
PDX
- GSP
1 stop7h 34m
American Airlines
Wed 9/165:24 pm
GSP
- PDX
1 stop8h 59m
American Airlines
Deal found 7/27![American Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:15 pm
PDX
- CHS
2 stops11h 51m
United Airlines
Thu 11/269:55 am
CHS
- PDX
1 stop8h 25m
United Airlines
Deal found 7/25![United Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:45 pm
PDX
- MYR
1 stop8h 20m
Southwest
Thu 8/273:20 pm
MYR
- PDX
2 stops10h 45m
Southwest
Deal found 7/25![Southwest logo]()
$374
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:40 am
PDX
- GSP
2 stops10h 18m
United Airlines
Wed 9/305:46 pm
GSP
- PDX
1 stop7h 37m
United Airlines
Deal found 7/28![United Airlines logo]()
$374
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:24 pm
PDX
- CHS
1 stop6h 35m
Delta
Tue 11/175:20 am
CHS
- PDX
1 stop8h 25m
Delta
Deal found 7/27![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:30 pm
PDX
- CHS
2 stops13h 40m
Southwest
Sat 9/126:45 am
CHS
- PDX
1 stop6h 55m
Southwest
Deal found 7/24![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:56 am
PDX
- CHS
2 stops10h 15m
United Airlines
Wed 9/306:30 am
CHS
- PDX
1 stop8h 03m
United Airlines
Deal found 7/25![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am
PDX
- CAE
1 stop7h 30m
American Airlines
Sun 11/157:30 am
CAE
- PDX
1 stop9h 14m
American Airlines
Deal found 7/28![American Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:02 pm
PDX
- CAE
1 stop7h 41m
United Airlines
Wed 9/91:48 pm
CAE
- PDX
1 stop11h 15m
United Airlines
Deal found 7/28![United Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:10 pm
PDX
- CAE
1 stop6h 39m
Delta
Thu 9/243:53 pm
CAE
- PDX
1 stop8h 54m
Delta
Deal found 7/27![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:45 pm
PDX
- MYR
1 stop8h 20m
Southwest
Thu 8/273:20 pm
MYR
- PDX
2 stops10h 45m
Southwest
Deal found 7/25![Southwest logo]()
$374
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:58 am
PDX
- CAE
1 stop7h 29m
American Airlines
Wed 9/97:00 am
CAE
- PDX
1 stop9h 17m
American Airlines
Deal found 7/25![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:27 pm
PDX
- CAE
2 stops11h 19m
United Airlines
Sat 9/265:37 pm
CAE
- PDX
1 stop7h 46m
United Airlines
Deal found 7/27![United Airlines logo]()
$366
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:08 pm
PDX
- CAE
1 stop6h 46m
Delta
Mon 9/71:59 pm
CAE
- PDX
1 stop7h 56m
Delta
Deal found 7/26![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:30 pm
PDX
- GSP
2 stops10h 10m
Southwest
Wed 9/305:30 pm
GSP
- PDX
2 stops8h 45m
Southwest
Deal found 7/28![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:30 pm
PDX
- GSP
1 stop7h 28m
United Airlines
Wed 9/306:20 am
GSP
- PDX
1 stop8h 13m
United Airlines
Deal found 7/28![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:30 pm
PDX
- GSP
2 stops10h 00m
Southwest
Tue 9/17:00 am
GSP
- PDX
2 stops10h 05m
Southwest
Deal found 7/26![Southwest logo]()
$379
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:30 am
PDX
- GSP
1 stop9h 41m
American Airlines
Sun 11/15:17 pm
GSP
- PDX
1 stop9h 24m
American Airlines
Deal found 7/24![American Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:00 am
PDX
- GSP
1 stop8h 49m
Delta
Fri 1/85:05 pm
GSP
- PDX
1 stop8h 21m
Delta
Deal found 7/27![Delta logo]()
$402
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:43 am
PDX
- GSP
1 stop7h 34m
United Airlines
Tue 10/202:16 pm
GSP
- PDX
2 stops9h 54m
United Airlines
Deal found 7/26![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:50 am
PDX
- GSP
2 stops12h 10m
Southwest
Wed 9/301:20 pm
GSP
- PDX
2 stops11h 55m
Southwest
Deal found 7/26![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:15 pm
PDX
- CHS
1 stop10h 57m
Delta
Fri 10/162:05 pm
CHS
- PDX
1 stop8h 04m
Delta
Deal found 7/28![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:44 pm
PDX
- MYR
1 stop9h 49m
American Airlines
Tue 9/158:08 am
MYR
- PDX
2 stops11h 46m
American Airlines
Deal found 7/24![American Airlines logo]()
$451
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:40 am
PDX
- GSP
2 stops10h 18m
United Airlines
Wed 9/305:46 pm
GSP
- PDX
1 stop7h 37m
United Airlines
Deal found 7/28![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:30 pm
PDX
- SAV
2 stops10h 00m
Southwest
Mon 8/314:10 pm
SAV
- PDX
2 stops10h 30m
Southwest
Deal found 7/26![Southwest logo]()
$395
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:50 pm
PDX
- CHS
1 stop8h 20m
Delta
Sat 11/76:00 am
CHS
- PDX
2 stops11h 54m
Delta
Deal found 7/25![Delta logo]()
$411
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:43 am
PDX
- SAV
1 stop7h 51m
United Airlines
Wed 10/212:10 pm
SAV
- PDX
1 stop9h 00m
United Airlines
Deal found 7/27![United Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:30 pm
PDX
- SAV
2 stops10h 00m
Southwest
Sat 10/31:05 pm
SAV
- PDX
2 stops11h 20m
Southwest
Deal found 7/25![Southwest logo]()
$395
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:00 pm
PDX
- HHH
2 stops17h 05m
American Airlines
Tue 10/2712:29 pm
HHH
- PDX
1 stop9h 10m
American Airlines
Deal found 7/26![American Airlines logo]()
$491
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:33 pm
PDX
- CHS
2 stops10h 10m
Delta
Mon 11/163:23 pm
CHS
- PDX
2 stops11h 33m
Delta
Deal found 7/27![Delta logo]()
$413
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:07 pm
PDX
- MYR
2 stops11h 37m
United Airlines
Thu 8/2710:23 am
MYR
- PDX
2 stops15h 29m
United Airlines
Deal found 7/28![United Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2710:45 pm
PDX
- CHS
1 stop9h 05m
Southwest
Wed 9/301:15 pm
CHS
- PDX
1 stop7h 30m
Southwest
Deal found 7/28![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:15 pm
PDX
- SAV
1 stop9h 20m
Delta
Tue 10/135:30 am
SAV
- PDX
1 stop8h 12m
Delta
Deal found 7/24![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:33 pm
PDX
- HHH
1 stop11h 02m
United Airlines
Sat 10/33:00 pm
HHH
- PDX
1 stop10h 23m
United Airlines
Deal found 7/25![United Airlines logo]()
$419
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated July 29, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:45 pm
PDX
- MYR
1 stop12h 05m
Southwest
Thu 8/273:20 pm
MYR
- PDX
2 stops10h 45m
Southwest
Deal found 7/28![Southwest logo]()
$380
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:02 pm
PDX
- CHS
1 stop8h 34m
United Airlines
Tue 9/13:20 pm
CHS
- PDX
1 stop9h 43m
United Airlines
Deal found 7/26![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:45 pm
PDX
- MYR
1 stop8h 20m
Southwest
Thu 8/273:20 pm
MYR
- PDX
2 stops10h 45m
Southwest
Deal found 7/25![Southwest logo]()
$374
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:02 pm
PDX
- CAE
2 stops12h 19m
United Airlines
Mon 8/315:38 pm
CAE
- PDX
1 stop8h 14m
United Airlines
Deal found 7/25![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:45 pm
PDX
- SAV
1 stop8h 25m
Southwest
Mon 8/3111:25 am
SAV
- PDX
2 stops10h 35m
Southwest
Deal found 7/26![Southwest logo]()
$390
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:55 pm
PDX
- MYR
1 stop8h 52m
Delta
Tue 9/16:00 am
MYR
- PDX
1 stop7h 27m
Delta
Deal found 7/26![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:58 am
PDX
- GSP
1 stop7h 19m
American Airlines
Sat 8/291:37 pm
GSP
- PDX
1 stop9h 11m
American Airlines
Deal found 7/24![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:25 am
PDX
- GSP
1 stop7h 40m
United Airlines
Sat 8/2910:17 am
GSP
- PDX
2 stops10h 33m
United Airlines
Deal found 7/24![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:05 am
PDX
- GSP
2 stops10h 50m
Southwest
Sat 8/296:45 am
GSP
- PDX
2 stops10h 15m
Southwest
Deal found 7/24![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:10 am
PDX
- SAV
1 stop8h 11m
United Airlines
Wed 9/23:23 pm
SAV
- PDX
1 stop9h 40m
United Airlines
Deal found 7/26![United Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:58 am
PDX
- CAE
1 stop7h 29m
American Airlines
Wed 9/97:00 am
CAE
- PDX
1 stop9h 17m
American Airlines
Deal found 7/26![American Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:08 pm
PDX
- CAE
1 stop6h 46m
Delta
Mon 9/71:59 pm
CAE
- PDX
1 stop7h 56m
Delta
Deal found 7/28![Delta logo]()
$379
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This Expedia deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:56 pm
PDX
- CLT
1 stop19h 30m
Frontier
Deal found 7/25![Frontier logo]()
$147
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:35 pm
PDX
- CLT
1 stop22h 16m
Frontier
Deal found 7/27![Frontier logo]()
$152
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:38 pm
PDX
- CLT
1 stop27h 21m
Frontier
Deal found 7/25![Frontier logo]()
$153
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:30 pm
PDX
- CLT
1 stop9h 25m
Southwest
Deal found 7/24![Southwest logo]()
$156
This Expedia deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:34 pm
PDX
- CLT
1 stop27h 17m
Frontier
Deal found 7/27![Frontier logo]()
$160
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:30 pm
PDX
- CLT
2 stops10h 15m
Southwest
Deal found 7/25![Southwest logo]()
$161
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:35 am
PDX
- CLT
1 stop7h 15m
Southwest
Deal found 7/28![Southwest logo]()
$165
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:35 pm
PDX
- CHS
1 stop10h 32m
Delta
Deal found 7/28![Delta logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:56 pm
PDX
- CHS
2 stops11h 42m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1412:39 pm
PDX
- CHS
2 stops16h 59m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:00 am
PDX
- CLT
2 stops10h 50m
Southwest
Deal found 7/28![Southwest logo]()
$179
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:08 pm
PDX
- CHS
1 stop6h 50m
Delta
Deal found 7/28![Delta logo]()
$180
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $349 (Delta) |
One-way from | $147 (Expedia) |
Popular in | April |
Cheapest in | February |
Average price | $502 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Wed 11/11
2:24 pm-11:59 pm
1 stop6h 35m
Charleston
Tue 11/17
5:20 am-10:45 am
1 stop8h 25m
$349
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Sat 9/5
11:30 pm-4:10 pm
2 stops13h 40m
Charleston
Sat 9/12
6:45 am-10:40 am
1 stop6h 55m
$354
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Wed 9/23
10:56 am-12:11 am
2 stops10h 15m
Charleston
Wed 9/30
6:30 am-11:33 am
1 stop8h 03m
$354
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Wed 9/2
11:02 pm-9:43 am
1 stop7h 41m
Columbia Metropolitan
Wed 9/9
1:48 pm-10:03 pm
1 stop11h 15m
$361
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Wed 9/23
7:27 pm-9:46 am
2 stops11h 19m
Columbia Metropolitan
Sat 9/26
5:37 pm-10:23 pm
1 stop7h 46m
$366
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Sat 9/26
11:30 pm-9:58 am
1 stop7h 28m
Greenville
Wed 9/30
6:20 am-11:33 am
1 stop8h 13m
$369
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Tue 11/10
6:00 am-4:30 pm
1 stop7h 30m
Columbia Metropolitan
Sun 11/15
7:30 am-1:44 pm
1 stop9h 14m
$370
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Thu 9/10
2:10 pm-11:49 pm
1 stop6h 39m
Columbia Metropolitan
Thu 9/24
3:53 pm-9:47 pm
1 stop8h 54m
$370
PortlandMyrtle Beach
PDX - MYR
PDXMYR
Portland
Mon 8/24
10:45 pm-10:05 am
1 stop8h 20m
Myrtle Beach Intl
Thu 8/27
3:20 pm-11:05 pm
2 stops10h 45m
$374
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Wed 9/30
10:43 am-9:17 pm
1 stop7h 34m
Greenville
Tue 10/20
2:16 pm-9:10 pm
2 stops9h 54m
$374
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PDX-CLT
PDX-CHS
PDX-GSP
PDX-CAE
PDX-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PDX-USSC
PDX-CLT
PDX-CHS
PDX-GSP
PDX-CAE
What is the cheapest month to book a flight from Portland to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Portland to South Carolina (average of $379). Flying from Portland to South Carolina in March is currently the most expensive (average of $620). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to South Carolina?
Airfare is typical for this route at the moment.
Portland to South Carolina flights typically cost between $348 and $496 in November.The cheapest round-trip price found within the last 5 days was $349 on Delta (Nov 3-Nov 7).
How far ahead should I book a flight from Portland to South Carolina?
Booking 45 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 29, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to South Carolina by cabin class
Find flights from Portland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on July 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$239 | Average$460 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$459 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$298 | Average$488 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$304 | Average$539 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$393 | Average$571 | FlexibilityNo cancel fee | On-time63% |