$146+ Cheap flights from Portland (PDX) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Portland to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This CheapOair deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:38 pm -
1 stop27h 21m
Sun 9/277:54 pm -
1 stop18h 49m
Deal found 9/3![Frontier logo]()
$323
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:35 pm -
1 stop8h 05m
Tue 11/37:40 am -
1 stop7h 55m
Deal found 9/3![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:35 pm -
1 stop13h 15m
Sat 10/3110:30 am -
2 stops11h 05m
Deal found 9/2![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:35 pm -
1 stop8h 20m
Tue 10/277:25 am -
1 stop8h 05m
Deal found 9/2![Southwest logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:12 pm -
1 stop7h 47m
Wed 10/213:41 pm -
1 stop10h 58m
Deal found 9/3![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:10 pm -
1 stop6h 39m
Sat 10/102:00 pm -
1 stop8h 09m
Deal found 9/3![Delta logo]()
$361
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:49 pm -
2 stops13h 21m
Wed 10/214:20 pm -
2 stops10h 39m
Deal found 9/6![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:33 pm -
2 stops11h 13m
Sat 10/105:38 pm -
1 stop7h 45m
Deal found 9/2![United Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop7h 34m
Thu 10/16:23 pm -
1 stop8h 44m
Deal found 9/2![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:30 pm -
1 stop7h 16m
Sat 10/35:38 pm -
1 stop7h 45m
Deal found 9/3![United Airlines logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:49 am -
2 stops17h 48m
Mon 10/194:47 pm -
1 stop21h 07m
Deal found 9/4![Frontier logo]()
$373
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:55 am -
2 stops8h 15m
Sat 12/1212:50 pm -
2 stops11h 35m
Deal found 9/4![Southwest logo]()
$379
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:35 pm -
2 stops10h 00m
Tue 11/36:40 am -
2 stops11h 20m
Deal found 9/3![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:30 pm -
2 stops11h 57m
Tue 11/104:15 pm -
1 stop7h 58m
Deal found 9/3![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:24 pm -
1 stop6h 34m
Tue 12/152:51 pm -
1 stop10h 05m
Deal found 9/3![Delta logo]()
$385
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:20 am -
1 stop8h 15m
Mon 11/25:17 pm -
1 stop7h 53m
Deal found 9/6![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:55 pm -
2 stops11h 52m
Sat 10/35:38 pm -
1 stop7h 45m
Deal found 9/3![United Airlines logo]()
$375
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:44 pm -
2 stops10h 26m
Sat 10/312:25 pm -
2 stops11h 17m
Deal found 9/4![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:35 pm -
2 stops9h 35m
Fri 10/301:05 pm -
2 stops10h 40m
Deal found 9/4![Southwest logo]()
$401
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:25 am -
1 stop7h 40m
Sat 10/243:00 pm -
2 stops10h 23m
Deal found 9/7![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:44 pm -
1 stop7h 53m
Fri 10/232:11 pm -
1 stop9h 33m
Deal found 9/6![American Airlines logo]()
$441
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:35 pm -
1 stop8h 20m
Mon 10/264:15 pm -
2 stops9h 30m
Deal found 9/3![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am -
1 stop7h 40m
Wed 11/43:35 pm -
1 stop10h 40m
Deal found 9/2![United Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:44 pm -
2 stops11h 51m
Wed 10/2111:15 am -
2 stops11h 45m
Deal found 9/5![Delta logo]()
$424
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:49 pm -
2 stops12h 53m
Tue 11/1712:02 pm -
1 stop10h 52m
Deal found 9/2![American Airlines logo]()
$451
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:35 pm -
1 stop8h 00m
Thu 10/227:25 pm -
1 stop7h 50m
Deal found 9/2![Southwest logo]()
$412
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:30 pm -
1 stop7h 52m
Tue 12/153:28 pm -
1 stop10h 40m
Deal found 9/3![United Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:52 am -
1 stop6h 52m
Wed 11/1112:24 pm -
2 stops12h 33m
Deal found 9/3![Delta logo]()
$431
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:01 am -
1 stop7h 18m
Wed 9/235:21 pm -
1 stop9h 02m
Deal found 9/4![American Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:55 am -
2 stops8h 15m
Wed 11/117:05 am -
2 stops9h 05m
Deal found 9/6![Southwest logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:30 pm -
1 stop7h 16m
Sat 10/33:03 pm -
1 stop8h 07m
Deal found 9/5![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:51 am -
1 stop9h 07m
Sun 11/155:30 am -
1 stop8h 11m
Deal found 9/3![Delta logo]()
$441
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:06 pm -
1 stop10h 09m
Sat 9/261:40 pm -
1 stop8h 56m
Deal found 9/7![American Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:30 pm -
1 stop7h 16m
Tue 10/275:37 pm -
1 stop7h 50m
Deal found 9/3![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:00 pm -
1 stop6h 59m
Thu 11/123:22 pm -
2 stops11h 14m
Deal found 9/3![Delta logo]()
$441
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:45 pm -
1 stop8h 30m
Wed 9/306:30 pm -
1 stop7h 45m
Deal found 9/2![Southwest logo]()
$442
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:30 pm -
1 stop7h 16m
Sat 10/310:29 am -
2 stops10h 17m
Deal found 9/6![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:20 am -
1 stop13h 30m
Mon 11/27:00 pm -
1 stop7h 55m
Deal found 9/6![Southwest logo]()
$445
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:25 am -
2 stops9h 34m
Tue 11/108:00 am -
2 stops13h 55m
Deal found 9/6![Delta logo]()
$449
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:24 pm -
1 stop6h 35m
Sun 11/155:20 am -
1 stop8h 21m
Deal found 9/2![Delta logo]()
$456
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:35 pm -
1 stop8h 05m
Mon 10/197:25 pm -
1 stop7h 50m
Deal found 9/4![Southwest logo]()
$463
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:30 am -
1 stop9h 47m
Tue 9/294:25 pm -
1 stop7h 45m
Deal found 9/2![United Airlines logo]()
$432
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated September 7, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:38 pm -
1 stop27h 21m
Sun 9/277:54 pm -
1 stop18h 49m
Deal found 9/3![Frontier logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop7h 34m
Thu 10/16:23 pm -
1 stop8h 44m
Deal found 9/2![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:30 pm -
1 stop7h 16m
Sat 10/310:29 am -
1 stop8h 27m
Deal found 9/3![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:10 pm -
1 stop6h 39m
Sat 10/102:00 pm -
1 stop8h 09m
Deal found 9/3![Delta logo]()
$361
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:33 pm -
2 stops11h 13m
Sat 10/105:38 pm -
1 stop7h 45m
Deal found 9/2![United Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:49 am -
2 stops17h 48m
Mon 10/194:47 pm -
1 stop21h 07m
Deal found 9/4![Frontier logo]()
$373
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:12 pm -
1 stop7h 47m
Wed 10/213:41 pm -
1 stop10h 58m
Deal found 9/3![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:49 pm -
2 stops13h 21m
Wed 10/214:20 pm -
2 stops10h 39m
Deal found 9/6![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:15 pm -
1 stop10h 56m
Sat 10/316:00 am -
1 stop7h 42m
Deal found 9/4![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:35 pm -
1 stop8h 20m
Tue 10/277:25 am -
1 stop8h 05m
Deal found 9/2![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:35 pm -
1 stop13h 15m
Sat 10/3110:30 am -
2 stops11h 05m
Deal found 9/2![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:35 pm -
1 stop8h 05m
Tue 11/37:40 am -
1 stop7h 55m
Deal found 9/3![Southwest logo]()
$337
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Trip.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:02 pm -
2 stops17h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:49 am -
2 stops17h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:02 pm -
2 stops26h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:02 am -
2 stops18h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$152
This Trip.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:38 pm -
2 stops16h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$154
This Trip.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:38 pm -
2 stops16h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:25 pm -
2 stops41h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:02 pm -
2 stops41h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:45 pm -
2 stops23h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$166
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:45 pm -
1 stop8h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Southwest logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:02 am -
2 stops25h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:31 pm -
2 stops25h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$171
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $323 (CheapOair) |
One-way from | $146 (Trip.com) |
Popular in | April |
Cheapest in | January |
Average price | $546 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandCharlotte
PDX Portland - CLT Charlotte Douglas
PDXCLT
Portland
Wed 12/2
6:00 am-4:25 pm
1 stop7h 25m
Charlotte Douglas
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$169
Quickest round-trip
PortlandGreenville
PDX Portland - GSP Greenville
PDXGSP
Portland
Sat 10/24
11:00 pm-9:23 am
1 stop7h 23m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$185
PortlandGreenville
PDX Portland - GSP Greenville
PDXGSP
Portland
Sat 2/27
9:45 pm-9:25 am
1 stop8h 40m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$185
PortlandGreenville
PDX Portland - GSP Greenville
PDXGSP
Portland
Sat 10/24
6:50 am-8:58 pm
2 stops11h 08m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$190
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Tue 10/13
11:30 pm-10:27 am
1 stop7h 57m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$190
PortlandGreenville
PDX Portland - GSP Greenville
PDXGSP
Portland
Fri 10/23
11:30 pm-9:58 am
1 stop7h 28m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$196
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Fri 10/23
5:49 pm-9:25 am
2 stops12h 36m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$212
PortlandCharleston
PDX Portland - CHS Charleston
PDXCHS
Portland
Thu 10/22
11:30 pm-10:27 am
1 stop7h 57m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$219
PortlandCharlotte
PDX Portland - CLT Charlotte Douglas
PDXCLT
Portland
Mon 10/26
11:35 pm-10:40 am
1 stop8h 05m
Charlotte Douglas
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$220
PortlandGreenville
PDX Portland - GSP Greenville
PDXGSP
Portland
Sat 9/26
6:50 am-8:58 pm
2 stops11h 08m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$222
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PDX-CLT
PDX-CHS
PDX-CAE
PDX-GSP
PDX-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PDX-USSC
PDX-CLT
PDX-CHS
PDX-CAE
PDX-GSP
What is the cheapest month to book a flight from Portland to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Portland to South Carolina (average of $379). Flying from Portland to South Carolina in March is currently the most expensive (average of $620). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to South Carolina?
Airfare is below average for this route at the moment.
Portland to South Carolina flights typically cost between $397 and $512 in October.The cheapest round-trip price found within the last 5 days was $359 on American Airlines (Oct 17-Oct 21).
How far ahead should I book a flight from Portland to South Carolina?
Booking 88 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 7, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to South Carolina by cabin class
Find flights from Portland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$479 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$290 | Average$453 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$304 | Average$479 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$304 | Average$542 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$358 | Average$566 | FlexibilityNo cancel fee | On-time63% |