$92+ Cheap flights from Portland (PDX) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
mag 27 — giu 31
Round-trip
1 adult, Economy
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Find cheap flights from Portland to South Carolina with Cheapflights
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Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on aprile 27, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on aprile 27, 2026.
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 6/311:20 am
PDX
- CHS
1 stop8h 40m
American Airlines
mar 6/97:19 pm
CHS
- PDX
1 stop8h 31m
American Airlines
Deal found 4/23![American Airlines logo]()
$265
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 9/1511:55 am
PDX
- GSP
1 stop7h 05m
Delta
mar 9/226:45 am
GSP
- PDX
1 stop6h 52m
Delta
Deal found 4/23![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 8/2911:59 pm
PDX
- CHS
1 stop9h 41m
American Airlines
mar 9/13:41 pm
CHS
- PDX
1 stop10h 26m
American Airlines
Deal found 4/23![American Airlines logo]()
$270
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/29:39 pm
PDX
- GSP
1 stop8h 25m
Delta
mer 6/31:09 pm
GSP
- PDX
2 stops11h 53m
Delta
Deal found 4/24![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/22:06 pm
PDX
- CHS
1 stop6h 53m
Delta
sab 6/66:00 am
CHS
- PDX
1 stop8h 46m
Delta
Deal found 4/23![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 9/1511:30 pm
PDX
- GSP
2 stops9h 55m
Southwest
mar 9/227:00 am
GSP
- PDX
2 stops11h 00m
Southwest
Deal found 4/23![Southwest logo]()
$281
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/25:07 am
PDX
- GSP
1 stop8h 28m
American Airlines
mer 6/37:54 pm
GSP
- PDX
1 stop7h 56m
American Airlines
Deal found 4/23![American Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/2912:34 pm
PDX
- CHS
1 stop8h 22m
American Airlines
mar 6/96:18 pm
CHS
- PDX
1 stop8h 41m
American Airlines
Deal found 4/22![American Airlines logo]()
$294
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 6/19:39 pm
PDX
- CHS
1 stop8h 59m
Delta
sab 6/66:00 am
CHS
- PDX
1 stop8h 46m
Delta
Deal found 4/23![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 9/2111:30 pm
PDX
- CHS
2 stops10h 05m
Southwest
mer 9/301:15 pm
CHS
- PDX
1 stop7h 30m
Southwest
Deal found 4/23![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 6/111:12 pm
PDX
- GSP
1 stop8h 43m
Delta
mer 6/1011:38 am
GSP
- PDX
2 stops10h 46m
Delta
Deal found 4/23![Delta logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/282:44 pm
PDX
- MYR
1 stop21h 34m
Allegiant Air
sab 6/69:59 pm
MYR
- PDX
1 stop18h 49m
Allegiant Air
Deal found 4/26![Allegiant Air logo]()
$307
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated aprile 27, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated aprile 27, 2026.
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/29:39 pm
PDX
- GSP
1 stop8h 25m
Delta
mer 6/31:09 pm
GSP
- PDX
2 stops11h 53m
Delta
Deal found 4/24![Delta logo]()
$274
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/296:50 pm
PDX
- CHS
2 stops11h 01m
United Airlines
mar 6/96:30 pm
CHS
- PDX
1 stop8h 23m
United Airlines
Deal found 4/22![United Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/298:05 am
PDX
- CHS
2 stops9h 45m
Southwest
mar 6/94:15 pm
CHS
- PDX
2 stops9h 20m
Southwest
Deal found 4/22![Southwest logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/3012:35 pm
PDX
- MYR
2 stops18h 15m
Multiple Airlines
sab 6/69:59 pm
MYR
- PDX
1 stop18h 49m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 5/275:49 am
PDX
- AGS
1 stop9h 13m
American Airlines
mer 6/36:27 pm
AGS
- PDX
1 stop8h 32m
American Airlines
Deal found 4/24![American Airlines logo]()
$419
This Alaska Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/269:44 am
PDX
- CLT
2 stops11h 15m
Alaska Airlines
sab 5/301:05 pm
CLT
- PDX
2 stops13h 54m
Alaska Airlines
Deal found 4/25![Alaska Airlines logo]()
$605
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 6/511:12 pm
PDX
- CHS
1 stop10h 07m
Delta
lun 6/81:11 pm
CHS
- PDX
1 stop8h 38m
Delta
Deal found 4/22![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 7/1411:40 pm
PDX
- CHS
1 stop7h 28m
United Airlines
mer 7/2211:31 am
CHS
- PDX
1 stop10h 16m
United Airlines
Deal found 4/26![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 7/99:20 pm
PDX
- CHS
1 stop9h 35m
Southwest
mar 7/142:10 pm
CHS
- PDX
2 stops11h 25m
Southwest
Deal found 4/23![Southwest logo]()
$391
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 6/2411:40 pm
PDX
- CHS
1 stop7h 28m
United Airlines
lun 6/294:16 pm
CHS
- PDX
1 stop9h 47m
United Airlines
Deal found 4/26![United Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/179:39 pm
PDX
- CAE
1 stop8h 36m
Delta
dom 5/245:40 am
CAE
- PDX
2 stops9h 46m
Delta
Deal found 4/22![Delta logo]()
$394
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 7/1411:30 pm
PDX
- CHS
2 stops11h 00m
Southwest
mer 7/222:10 pm
CHS
- PDX
2 stops11h 25m
Southwest
Deal found 4/26![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 6/110:40 pm
PDX
- CHS
1 stop8h 28m
United Airlines
lun 6/86:30 pm
CHS
- PDX
1 stop8h 23m
United Airlines
Deal found 4/24![United Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 7/155:20 am
PDX
- SAV
2 stops10h 32m
American Airlines
mar 7/215:00 am
SAV
- PDX
2 stops10h 49m
American Airlines
Deal found 4/27![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 6/76:35 am
PDX
- SAV
1 stop6h 36m
Delta
mer 6/106:43 am
SAV
- PDX
1 stop9h 17m
Delta
Deal found 4/23![Delta logo]()
$415
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/265:40 am
PDX
- SAV
2 stops11h 20m
Southwest
mar 6/25:00 pm
SAV
- PDX
1 stop9h 10m
Southwest
Deal found 4/26![Southwest logo]()
$415
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/2611:40 pm
PDX
- SAV
1 stop7h 43m
United Airlines
mar 6/23:14 pm
SAV
- PDX
1 stop10h 16m
United Airlines
Deal found 4/26![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/237:40 pm
PDX
- GSP
2 stops11h 30m
Southwest
ven 5/296:25 pm
GSP
- PDX
2 stops8h 45m
Southwest
Deal found 4/24![Southwest logo]()
$418
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 5/272:06 pm
PDX
- AGS
1 stop6h 46m
Delta
mer 6/32:38 pm
AGS
- PDX
1 stop10h 08m
Delta
Deal found 4/25![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/511:23 pm
PDX
- HHH
1 stop10h 14m
American Airlines
mar 5/122:54 pm
HHH
- PDX
2 stops11h 54m
American Airlines
Deal found 4/26![American Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/2311:40 pm
PDX
- GSP
1 stop7h 31m
United Airlines
ven 5/295:41 pm
GSP
- PDX
1 stop8h 06m
United Airlines
Deal found 4/24![United Airlines logo]()
$408
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/195:18 pm
PDX
- CAE
2 stops12h 57m
Delta
mar 5/265:40 am
CAE
- PDX
2 stops13h 20m
Delta
Deal found 4/26![Delta logo]()
$424
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 6/247:40 pm
PDX
- CHS
2 stops14h 35m
Southwest
lun 6/295:55 pm
CHS
- PDX
1 stop9h 00m
Southwest
Deal found 4/26![Southwest logo]()
$427
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/245:49 am
PDX
- HHH
1 stop7h 43m
American Airlines
dom 5/312:03 pm
HHH
- PDX
1 stop10h 48m
American Airlines
Deal found 4/24![American Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 6/410:40 pm
PDX
- SAV
1 stop8h 43m
United Airlines
lun 6/83:14 pm
SAV
- PDX
1 stop10h 16m
United Airlines
Deal found 4/25![United Airlines logo]()
$421
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/306:00 am
PDX
- MYR
1 stop7h 40m
Delta
ven 7/36:00 am
MYR
- PDX
2 stops9h 40m
Delta
Deal found 4/25![Delta logo]()
$430
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/2911:55 pm
PDX
- MYR
1 stop8h 10m
Southwest
sab 6/62:00 pm
MYR
- PDX
1 stop8h 40m
Southwest
Deal found 4/27![Southwest logo]()
$436
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/710:23 pm
PDX
- CLT
Nonstop4h 59m
American Airlines
dom 5/106:34 pm
CLT
- PDX
Nonstop5h 29m
American Airlines
Deal found 4/22![American Airlines logo]()
$563
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/2210:40 pm
PDX
- CHS
1 stop8h 41m
United Airlines
dom 5/246:00 am
CHS
- PDX
1 stop8h 38m
United Airlines
Deal found 4/22![United Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/99:45 am
PDX
- GSP
2 stops11h 14m
Delta
dom 6/145:44 am
GSP
- PDX
2 stops8h 58m
Delta
Deal found 4/26![Delta logo]()
$451
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated aprile 27, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated aprile 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 5/279:47 pm
PDX
- CAE
1 stop9h 57m
American Airlines
sab 5/307:21 pm
CAE
- PDX
1 stop8h 29m
American Airlines
Deal found 4/27![American Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 5/278:11 pm
PDX
- CAE
2 stops12h 00m
Delta
sab 5/305:40 am
CAE
- PDX
1 stop7h 31m
Delta
Deal found 4/27![Delta logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/282:44 pm
PDX
- MYR
1 stop21h 34m
Allegiant Air
sab 6/69:59 pm
MYR
- PDX
1 stop18h 49m
Allegiant Air
Deal found 4/26![Allegiant Air logo]()
$307
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/289:39 pm
PDX
- CHS
1 stop8h 04m
Delta
ven 6/56:00 am
CHS
- PDX
1 stop8h 46m
Delta
Deal found 4/23![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/2810:59 pm
PDX
- CHS
2 stops10h 09m
American Airlines
ven 6/57:19 pm
CHS
- PDX
1 stop8h 31m
American Airlines
Deal found 4/22![American Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/289:39 pm
PDX
- CHS
1 stop8h 04m
Delta
gio 6/41:03 pm
CHS
- PDX
1 stop10h 58m
Delta
Deal found 4/23![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/2912:34 pm
PDX
- CHS
1 stop8h 22m
American Airlines
mar 6/96:18 pm
CHS
- PDX
1 stop8h 41m
American Airlines
Deal found 4/22![American Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/296:50 pm
PDX
- CHS
2 stops11h 01m
United Airlines
mar 6/96:30 pm
CHS
- PDX
1 stop8h 23m
United Airlines
Deal found 4/22![United Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/299:22 am
PDX
- MYR
2 stops32h 14m
Multiple Airlines
sab 6/69:59 pm
MYR
- PDX
1 stop18h 49m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$340
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/2911:30 pm
PDX
- CHS
1 stop7h 46m
United Airlines
ven 6/53:34 pm
CHS
- PDX
1 stop9h 14m
United Airlines
Deal found 4/22![United Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/3012:35 pm
PDX
- MYR
2 stops18h 15m
Multiple Airlines
sab 6/69:59 pm
MYR
- PDX
1 stop18h 49m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/312:44 pm
PDX
- MYR
1 stop21h 34m
Allegiant Air
sab 6/69:59 pm
MYR
- PDX
1 stop18h 49m
Allegiant Air
Deal found 4/26![Allegiant Air logo]()
$356
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated aprile 27, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated aprile 27, 2026.
This CheapOair deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/2312:35 pm
PDX
- CLT
1 stop26h 43m
Frontier
Deal found 4/25![Frontier logo]()
$92
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/95:20 pm
PDX
- CLT
1 stop25h 05m
Frontier
Deal found 4/23![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Allegiant Air
Deal found 4/27![Allegiant Air logo]()
$127
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/2911:15 am
PDX
- CLT
1 stop16h 44m
Frontier
Deal found 4/27![Frontier logo]()
$137
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 9/911:30 pm
PDX
- CLT
1 stop8h 40m
Southwest
Deal found 4/23![Southwest logo]()
$147
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/2311:43 pm
PDX
- CHS
1 stop9h 45m
American Airlines
Deal found 4/23![American Airlines logo]()
$148
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/2610:40 pm
PDX
- MYR
1 stop9h 05m
American Airlines
Deal found 4/23![American Airlines logo]()
$150
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 6/812:35 pm
PDX
- CLT
1 stop26h 44m
Frontier
Deal found 4/27![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/2412:35 pm
PDX
- CLT
2 stops24h 25m
Frontier
Deal found 4/23![Frontier logo]()
$153
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 5/2611:58 am
PDX
- MYR
2 stops9h 00m
Delta
Deal found 4/23![Delta logo]()
$155
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 6/1011:40 pm
PDX
- SAV
1 stop7h 43m
United Airlines
Deal found 4/23![United Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/242:44 pm
PDX
- CLT
3 stops44h 27m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$156
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated aprile 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $265 (American Airlines) |
One-way from | $92 (CheapOair) |
Popular in | April |
Cheapest in | January |
Average price | $546 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated aprile 27, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandGreenville
PDX - GSP
PDXGSP
Portland
mar 6/2
9:39 pm-9:04 am
1 stop8h 25m
Greenville
mer 6/3
1:09 pm-10:02 pm
2 stops11h 53m
$274
PortlandCharleston
PDX - CHS
PDXCHS
Portland
ven 6/5
11:12 pm-12:19 pm
1 stop10h 07m
Charleston
lun 6/8
1:11 pm-6:49 pm
1 stop8h 38m
$319
PortlandCharleston
PDX - CHS
PDXCHS
Portland
ven 5/29
6:50 pm-8:51 am
2 stops11h 01m
Charleston
mar 6/9
6:30 pm-11:53 pm
1 stop8h 23m
$336
PortlandCharleston
PDX - CHS
PDXCHS
Portland
ven 5/29
8:05 am-8:50 pm
2 stops9h 45m
Charleston
mar 6/9
4:15 pm-10:35 pm
2 stops9h 20m
$373
PortlandCharleston
PDX - CHS
PDXCHS
Portland
mar 7/14
11:40 pm-10:08 am
1 stop7h 28m
Charleston
mer 7/22
11:31 am-6:47 pm
1 stop10h 16m
$377
PortlandCharleston
PDX - CHS
PDXCHS
Portland
mer 6/24
11:40 pm-10:08 am
1 stop7h 28m
Charleston
lun 6/29
4:16 pm-11:03 pm
1 stop9h 47m
$386
PortlandCharleston
PDX - CHS
PDXCHS
Portland
gio 7/9
9:20 pm-9:55 am
1 stop9h 35m
Charleston
mar 7/14
2:10 pm-10:35 pm
2 stops11h 25m
$391
PortlandColumbia
PDX - CAE
PDXCAE
Portland
dom 5/17
9:39 pm-9:15 am
1 stop8h 36m
Columbia Metropolitan
dom 5/24
5:40 am-12:26 pm
2 stops9h 46m
$394
PortlandCharleston
PDX - CHS
PDXCHS
Portland
lun 6/1
10:40 pm-10:08 am
1 stop8h 28m
Charleston
lun 6/8
6:30 pm-11:53 pm
1 stop8h 23m
$395
PortlandMyrtle Beach
PDX - MYR
PDXMYR
Portland
sab 5/30
12:35 pm-9:50 am
2 stops18h 15m
Myrtle Beach Intl
sab 6/6
9:59 pm-1:48 pm
1 stop18h 49m
$399
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PDX-CHS
PDX-MYR
PDX-CAE
PDX-GSP
PDX-AGS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PDX-USSC
PDX-CHS
PDX-MYR
PDX-CAE
PDX-GSP
How far ahead should I book a flight from Portland to South Carolina?
Booking 45 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Portland to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Portland to South Carolina (average of $129). Flying from Portland to South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated aprile 27, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to South Carolina by cabin class
Find flights from Portland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on aprile 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated aprile 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$452 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$452 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$294 | Average$523 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$298 | Average$602 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$329 | Average$540 | FlexibilityNo cancel fee | On-time63% |