$170+ Cheap flights from Knoxville to Portland, ME (TYS - PWM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PWM
May 9 — May 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Portland with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Portland
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to PortlandExplore the most affordable flight options available from Knoxville to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Knoxville to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:15 am
TYS
- PWM
1 stop7h 05m
Southwest
Tue 5/123:55 pm
PWM
- TYS
1 stop4h 55m
Southwest
Deal found 4/4![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:30 am
TYS
- PWM
1 stop7h 56m
United Airlines
Sat 5/306:25 pm
PWM
- TYS
1 stop6h 05m
United Airlines
Deal found 4/9![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:15 am
TYS
- PWM
1 stop7h 05m
Southwest
Mon 5/412:45 pm
PWM
- TYS
2 stops7h 35m
Southwest
Deal found 4/6![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:45 pm
TYS
- PWM
2 stops9h 20m
Southwest
Tue 8/117:45 am
PWM
- TYS
2 stops12h 05m
Southwest
Deal found 4/4![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:50 am
TYS
- PWM
1 stop7h 15m
Southwest
Sat 10/310:35 am
PWM
- TYS
1 stop7h 05m
Southwest
Deal found 4/6![Southwest logo]()
$339
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:50 pm
TYS
- PWM
2 stops9h 45m
Southwest
Sat 5/305:40 am
PWM
- TYS
2 stops12h 50m
Southwest
Deal found 4/9![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:07 pm
TYS
- PWM
1 stop5h 11m
Delta
Tue 6/96:57 pm
PWM
- TYS
1 stop4h 57m
Delta
Deal found 4/7![Delta logo]()
$345
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:54 pm
TYS
- PWM
1 stop7h 21m
Delta
Mon 6/156:57 pm
PWM
- TYS
1 stop4h 57m
Delta
Deal found 4/6![Delta logo]()
$358
Best flights from Knoxville to PortlandDiscover carefully curated flight deals from Knoxville to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Knoxville to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
TYS
- PWM
1 stop4h 23m
Delta
Tue 6/96:57 pm
PWM
- TYS
1 stop4h 57m
Delta
Deal found 4/4![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:30 am
TYS
- PWM
1 stop7h 56m
United Airlines
Sat 5/306:25 pm
PWM
- TYS
1 stop6h 05m
United Airlines
Deal found 4/9![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:45 pm
TYS
- PWM
2 stops10h 10m
Southwest
Wed 7/83:45 pm
PWM
- TYS
1 stop5h 30m
Southwest
Deal found 4/4![Southwest logo]()
$330
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:10 pm
TYS
- PWM
1 stop7h 13m
American Airlines
Sat 9/265:30 pm
PWM
- TYS
1 stop4h 04m
American Airlines
Deal found 4/9![American Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:00 am
TYS
- PWM
1 stop7h 15m
Southwest
Tue 8/117:45 am
PWM
- TYS
2 stops11h 10m
Southwest
Deal found 4/4![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:35 pm
TYS
- PWM
1 stop5h 54m
Delta
Mon 6/2911:02 am
PWM
- TYS
1 stop5h 41m
Delta
Deal found 4/8![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:20 pm
TYS
- PWM
2 stops9h 45m
Southwest
Wed 7/223:45 pm
PWM
- TYS
1 stop5h 30m
Southwest
Deal found 4/5![Southwest logo]()
$344
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:19 pm
TYS
- PWM
1 stop4h 32m
United Airlines
Wed 7/225:15 am
PWM
- TYS
1 stop5h 27m
United Airlines
Deal found 4/5![United Airlines logo]()
$401
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:50 am
TYS
- PWM
2 stops8h 10m
Southwest
Sat 10/35:40 am
PWM
- TYS
2 stops8h 40m
Southwest
Deal found 4/6![Southwest logo]()
$349
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
TYS
- PWM
1 stop7h 14m
United Airlines
Tue 5/129:50 am
PWM
- TYS
1 stop4h 44m
United Airlines
Deal found 4/5![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:15 am
TYS
- PWM
1 stop7h 05m
Southwest
Sat 4/255:40 am
PWM
- TYS
2 stops11h 15m
Southwest
Deal found 4/6![Southwest logo]()
$394
Last-minute flights from Knoxville to PortlandDiscover last-minute flight deals from Knoxville to Portland. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Portland. Data last updated April 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
TYS
- PWM
1 stop4h 07m
American Airlines
Sat 4/256:00 am
PWM
- TYS
1 stop5h 01m
American Airlines
Deal found 4/6![American Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:15 am
TYS
- PWM
1 stop7h 05m
Southwest
Sat 4/255:40 am
PWM
- TYS
2 stops11h 15m
Southwest
Deal found 4/6![Southwest logo]()
$394
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:15 am
TYS
- PWM
1 stop7h 05m
Southwest
Mon 5/412:45 pm
PWM
- TYS
2 stops7h 35m
Southwest
Deal found 4/6![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:15 am
TYS
- PWM
1 stop7h 05m
Southwest
Tue 5/123:55 pm
PWM
- TYS
1 stop4h 55m
Southwest
Deal found 4/4![Southwest logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:38 pm
TYS
- PWM
1 stop4h 48m
American Airlines
Sun 5/176:00 am
PWM
- TYS
1 stop7h 15m
American Airlines
Deal found 4/5![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:05 am
TYS
- PWM
1 stop6h 05m
Southwest
Sun 5/175:30 am
PWM
- TYS
2 stops15h 35m
Southwest
Deal found 4/5![Southwest logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:00 am
TYS
- PWM
2 stops30h 31m
Multiple Airlines
Mon 5/259:52 am
PWM
- TYS
1 stop13h 45m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:30 am
TYS
- PWM
1 stop7h 56m
United Airlines
Sat 5/306:25 pm
PWM
- TYS
1 stop6h 05m
United Airlines
Deal found 4/9![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:50 pm
TYS
- PWM
2 stops9h 45m
Southwest
Sat 5/305:40 am
PWM
- TYS
2 stops12h 50m
Southwest
Deal found 4/9![Southwest logo]()
$341
One-way flights from Knoxville to PortlandSearch for one-way flight options from Knoxville to Portland. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Knoxville to Portland. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:12 am
TYS
- PWM
1 stop6h 19m
American Airlines
Deal found 4/6![American Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:52 pm
TYS
- PWM
2 stops10h 07m
United Airlines
Deal found 4/9![United Airlines logo]()
$175
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:35 pm
TYS
- PWM
2 stops11h 30m
Southwest
Deal found 4/7![Southwest logo]()
$181
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:45 am
TYS
- PWM
1 stop4h 10m
Southwest
Deal found 4/9![Southwest logo]()
$195
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:45 am
TYS
- PWM
1 stop4h 22m
United Airlines
Deal found 4/6![United Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:40 pm
TYS
- PWM
3 stops42h 36m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/221:02 pm
TYS
- PWM
3 stops25h 29m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$211
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2212:35 pm
TYS
- PWM
2 stops11h 30m
Southwest
Deal found 4/7![Southwest logo]()
$216
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:00 am
TYS
- PWM
2 stops7h 40m
American Airlines
Deal found 4/7![American Airlines logo]()
$224
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:07 pm
TYS
- PWM
1 stop4h 40m
American Airlines
Deal found 4/7![American Airlines logo]()
$239
Find flight deals from Knoxville to Portland
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Portland (PWM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (Southwest) |
One-way from | $170 (American Airlines) |
Popular in | November |
Cheapest in | September |
Average price | $446 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Knoxville to Portland that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Thu 6/4
6:00 am-10:23 am
1 stop4h 23m
Portland
Tue 6/9
6:57 pm-11:54 pm
1 stop4h 57m
$325
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Wed 5/27
6:30 am-2:26 pm
1 stop7h 56m
Portland
Sat 5/30
6:25 pm-12:30 am
1 stop6h 05m
$325
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Wed 7/1
12:45 pm-10:55 pm
2 stops10h 10m
Portland
Wed 7/8
3:45 pm-9:15 pm
1 stop5h 30m
$330
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Tue 8/4
7:00 am-2:15 pm
1 stop7h 15m
Portland
Tue 8/11
7:45 am-6:55 pm
2 stops11h 10m
$330
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Wed 6/24
5:35 pm-11:29 pm
1 stop5h 54m
Portland
Mon 6/29
11:02 am-4:43 pm
1 stop5h 41m
$335
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Thu 7/16
2:20 pm-12:05 am
2 stops9h 45m
Portland
Wed 7/22
3:45 pm-9:15 pm
1 stop5h 30m
$344
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Sat 9/26
6:50 am-3:00 pm
2 stops8h 10m
Portland
Sat 10/3
5:40 am-2:20 pm
2 stops8h 40m
$349
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Sat 9/19
1:10 pm-8:23 pm
1 stop7h 13m
Portland
Sat 9/26
5:30 pm-9:34 pm
1 stop4h 04m
$359
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Tue 4/21
8:15 am-3:20 pm
1 stop7h 05m
Portland
Sat 4/25
5:40 am-4:55 pm
2 stops11h 15m
$394
KnoxvillePortland
TYS - PWM
TYSPWM
Knoxville McGhee Tyson
Thu 7/16
7:19 pm-11:51 pm
1 stop4h 32m
Portland
Wed 7/22
5:15 am-10:42 am
1 stop5h 27m
$401
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Portland
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Portland in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Portland, Maine flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Portland, Maine flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Portland, Maine flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Portland, Maine flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Portland, Maine flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Portland
Have a flexible travel schedule? Discover the best time to fly to Portland from Knoxville with our price prediction graph.
TYS-PWM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Portland
What is the cheapest month to book a flight from Knoxville to Portland, Maine?
Currently, July is the cheapest month in which you can book a flight from Knoxville to Portland, Maine (average of $63). Flying from Knoxville to Portland, Maine in January is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Portland, Maine?
Reviews of airlines servicing Portland
Get insights into the airlines that provide service to Portland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portland. Reviews last updated April 9, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Knoxville to Portland. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Portland?
Book flights to Portland if you plan to visit one of these locationsNorth Conway
Brunswick
Auburn
Lewiston
Conway
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Knoxville
Popular flights
Portland flight routes
Alternative routes for Knoxville to Portland
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Portland by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Portland by cabin class
Find flights from Knoxville to Portland, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Portland flights
Browse other Knoxville and Portland flight options. Last updated on April 9, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Portland
Explore flights to Portland departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 9, 2026.
Top 4 airlines flying from Knoxville to Portland
Discover the top 4 airlines that operate flights from Knoxville to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$389 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$258 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$423 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$328 | FlexibilityNo cancel fee | On-time63% |