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$124+ Cheap flights from Knoxville to Portland, ME (TYS - PWM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PWM
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Portland are usually found in January or September, booked 72 days in advance, depart on a Wednesday or Thursday and return on a Saturday

Find flight deals from Knoxville to Portland

Cheapest flights from Knoxville to Portland
Explore the most affordable flight options available from Knoxville to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/610:55 amTYS - PWM
1 stop7h 20mAmerican Airlines
Sun 12/75:34 amPWM - TYS
1 stop5h 19mAmerican Airlines
Deal found 11/6$279
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/24:38 pmTYS - PWM
2 stops7h 03mAmerican Airlines
Tue 12/95:34 amPWM - TYS
1 stop5h 16mAmerican Airlines
Deal found 11/5$284
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:55 amTYS - PWM
1 stop27h 14mMultiple Airlines
Fri 12/56:05 pmPWM - TYS
2 stops17h 58mMultiple Airlines
Deal found 11/5$298
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:59 pmTYS - PWM
1 stop6h 38mAmerican Airlines
Sat 12/135:34 amPWM - TYS
2 stops7h 31mAmerican Airlines
Deal found 11/4$314
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:12 pmTYS - PWM
1 stop18h 57mMultiple Airlines
Fri 12/56:05 pmPWM - TYS
2 stops17h 58mMultiple Airlines
Deal found 11/5$325
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/193:37 pmTYS - PWM
1 stop7h 17mAmerican Airlines
Sun 11/235:21 pmPWM - TYS
1 stop4h 12mAmerican Airlines
Deal found 11/4$329
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:55 amTYS - PWM
1 stop27h 14mMultiple Airlines
Wed 12/36:18 pmPWM - TYS
2 stops38h 15mMultiple Airlines
Deal found 11/5$338

Cheap flight deals from Knoxville to Portland

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Portland (PWM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(Delta)

One-way from

$124
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$376
Provider with most accurate pricing for Knoxville McGhee Tyson-Portland flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Portland flights.
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From Knoxville McGhee Tyson to Portland
Search Deals
One-way flight from Knoxville McGhee Tyson to Portland
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Knoxville to Portland that are best for you.

Fly from

Knoxville

Fly to

Portland

Route

Depart

Return

Price

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sat 12/6

10:55 am-6:15 pm

1 stop7h 20m

Portland

Sun 12/7

5:34 am-10:53 am

1 stop5h 19m

$279

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 3/25

7:30 am-11:57 am

1 stop4h 27m

Portland

Sat 3/28

4:50 pm-9:32 pm

1 stop4h 42m

$279

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Thu 12/11

4:59 pm-11:37 pm

1 stop6h 38m

Portland

Sat 12/13

5:34 am-10:50 am

1 stop5h 16m

$309

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Tue 12/2

4:38 pm-11:41 pm

2 stops7h 03m

Portland

Tue 12/9

5:34 am-12:04 pm

2 stops6h 30m

$319

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 11/19

3:37 pm-10:54 pm

1 stop7h 17m

Portland

Sun 11/23

5:21 pm-9:33 pm

1 stop4h 12m

$329

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Mon 12/1

12:50 pm-10:36 am

2 stops45h 46m

Portland

Mon 12/8

9:46 am-9:49 pm

1 stop12h 03m

$343

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Mon 12/22

3:45 pm-10:09 am

1 stop18h 24m

$124

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 12/24

8:35 am-10:09 am

1 stop25h 34m

$130

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Thu 12/25

7:39 am-12:17 pm

1 stop4h 38m

$140

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Mon 11/17

5:35 am-12:30 pm

1 stop6h 55m

$165

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 17 results
1
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Compare providers for flights from Knoxville to Portland

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Portland in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Portland, Maine flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Portland, Maine flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Portland, Maine flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Portland, Maine flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Portland, Maine flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Portland

How far ahead should I book a flight from Knoxville to Portland, Maine?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Portland. Price data was last updated on October 31, 2025.

Booking 24 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Portland, Maine. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Portland, Maine?

Currently, July is the cheapest month in which you can book a flight from Knoxville to Portland, Maine (average of $63). Flying from Knoxville to Portland, Maine in January is currently the most expensive (average of $193). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to PWM?

Find hourly flight availability from Knoxville to Portland. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

It’s typically best to fly out from Knoxville to Portland, Maine at noon. Doing so could potentially save you 56% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Portland

Get insights into the airlines that provide service to Portland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portland. Reviews last updated November 6, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Portland. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,007 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Portland, Maine?

    There are many flights that can get you from Knoxville to Portland, Maine in 4h 27m. Fly via American Airlines or Delta to get the fastest option. The distance from Knoxville to Portland, Maine is about 904 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Portland, Maine round-trip?

    Cheapflights users have booked flights from Knoxville to Portland, Maine round-trip from $246. Other airlines that can offer you cheap pricing are United Airlines, from $258, and American Airlines, from $258. Delta is 31% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Portland that include hotel bookings?

    Yes. In addition to deals on Knoxville to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Portland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Portland.

  • Can I find deals for business class flights from Knoxville to Portland?

    Yes. Cheapflights offers flight deals from Knoxville to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Portland, Maine?

    Currently, July is the cheapest month in which you can book a flight from Knoxville to Portland, Maine (average of $63). Flying from Knoxville to Portland, Maine in January is currently the most expensive (average of $193). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
North Conway
Brunswick
Auburn
Conway

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Top 3 airlines flying from Knoxville to Portland

Discover the top 3 airlines that operate flights from Knoxville to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$246Average$333FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$442FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$258Average$359FlexibilityNo cancel feeOn-time71%

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