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$500+ Cheap flights from Wilmington (ILM) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — PTY
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Wilmington to Panama

Keep the following information in mind while searching for Wilmington to Panama flight deals. Data was last updated September 17, 2025.

Round-trip from

$500
(Delta)

Popular in

June

Cheapest in

August

Average price

$572
From Wilmington New Hanover County to Panama
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($108 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Wilmington to Panama

Cheapest flights from Wilmington to Panama
Explore the most affordable flight options available from Wilmington to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2010:16 amILM - PTY
1 stop27h 40mDelta
Tue 10/282:21 pmPTY - ILM
1 stop7h 18mDelta
Deal found 9/16$500
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/204:26 pmILM - PTY
2 stops22h 37mAmerican Airlines
Tue 10/283:15 pmPTY - ILM
2 stops17h 18mAmerican Airlines
Deal found 9/16$514
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:18 pmILM - PTY
2 stops19h 35mAmerican Airlines
Mon 1/54:56 pmPTY - ILM
1 stop26h 03mAmerican Airlines
Deal found 9/15$840
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amILM - PTY
1 stop14h 00mDelta
Mon 1/58:10 amPTY - ILM
1 stop15h 44mDelta
Deal found 9/15$2,157
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:23 amILM - PTY
1 stop27h 32mDelta
Sun 1/48:00 amPTY - ILM
1 stop25h 37mDelta
Deal found 9/15$2,182

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Wilmington to Panama that are best for you.

Fly from

Wilmington

Fly to

Panama

Route

Depart

Return

Price

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Mon 10/20

10:16 am-12:56 pm

1 stop27h 40m

Panama City Tocumen Intl

Tue 10/28

2:21 pm-10:39 pm

1 stop7h 18m

$500

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 1/17

6:00 am-1:10 pm

1 stop7h 10m

Panama City Tocumen Intl

Sun 2/15

2:30 pm-11:07 pm

1 stop8h 37m

$512

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Mon 10/20

4:26 pm-2:03 pm

2 stops22h 37m

Panama City Tocumen Intl

Tue 10/28

3:15 pm-9:33 am

2 stops17h 18m

$514

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Wilmington to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to Panama

What is the cheapest time of day to fly from ILM to PA?

Find hourly flight availability from Wilmington to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Wilmington to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown American Airlines from Wilmington to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Wilmington to Panama?

    Most people fly from Wilmington New Hanover County (ILM) if they book a flight from Wilmington to Panama. Wilmington New Hanover County is conveniently located just 4.3 mi from Wilmington’s city center.

  • How long is the flight from Wilmington to Panama?

    There are many flights that can get you from Wilmington to Panama in 7h 10m. Fly via Delta or American Airlines to get the fastest option. There are 1742 mi between Wilmington and Panama. This flight may include one or multiple stops.

  • Can I find deals for flights from Wilmington to Panama that include hotel bookings?

    Yes. In addition to deals on Wilmington to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Panama.

  • Can I find deals for business class flights from Wilmington to Panama?

    Yes. Cheapflights offers flight deals from Wilmington to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilmington to Panama?

    Currently, October is the cheapest month in which you can book a flight from Wilmington to Panama (average of $478). Flying from Wilmington to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Wilmington to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Wilmington to Panama

Discover the top airline that operate flights from Wilmington to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$491Average$632FlexibilityNo cancel feeOn-time71%

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