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Panama

$236+ Cheap flights from Wilmington (ILM) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — PTY
Mar 8 — Mar 151
Sun 3/8
Sun 3/15
1 adult, Economy
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Cheap flight deals from Wilmington to Panama

Cheapest flights from Wilmington to Panama
Explore the most affordable flight options available from Wilmington to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.

This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
ILM
-
PTY
1 stop7h 10m
American Airlines
Thu 9/103:40 pm
PTY
-
ILM
1 stop6h 38m
American Airlines
Deal found 2/4$457
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
ILM
-
PTY
1 stop7h 46m
American Airlines
Sat 5/161:49 pm
PTY
-
ILM
2 stops21h 46m
American Airlines
Deal found 2/2$501
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:11 pm
ILM
-
PTY
2 stops19h 29m
American Airlines
Sun 5/31:49 pm
PTY
-
ILM
2 stops21h 40m
American Airlines
Deal found 2/6$506
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:33 pm
ILM
-
PTY
1 stop19h 13m
American Airlines
Sat 5/91:49 pm
PTY
-
ILM
2 stops21h 22m
American Airlines
Deal found 2/3$511
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
ILM
-
PTY
1 stop7h 55m
Delta
Sat 5/162:20 pm
PTY
-
ILM
1 stop7h 58m
Delta
Deal found 2/2$557
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:47 pm
ILM
-
PTY
1 stop17h 53m
American Airlines
Tue 3/101:40 pm
PTY
-
ILM
2 stops19h 53m
American Airlines
Deal found 2/3$562

Find flight deals from Wilmington to Panama

Keep the following information in mind while searching for Wilmington to Panama flight deals. Data was last updated February 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$457
(American Airlines)

One-way from

$236
(Delta)

Popular in

June

Cheapest in

August

Average price

$855
Provider with most accurate pricing for Wilmington New Hanover County-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Wilmington New Hanover County-Panama City Tocumen Intl flights.
Search Deals
From Wilmington New Hanover County to Panama
Search Deals
One-way flight from Wilmington New Hanover County to Panama
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Wilmington to Panama that are best for you.

Fly from

Wilmington

Fly to

Panama

Route

Depart

Return

Price

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 7/28

6:00 am-12:10 pm

1 stop7h 10m

Panama City Tocumen Intl

Thu 9/10

3:40 pm-11:18 pm

1 stop6h 38m

$457

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sun 5/10

6:00 am-12:46 pm

1 stop7h 46m

Panama City Tocumen Intl

Sat 5/16

1:49 pm-12:35 pm

2 stops21h 46m

$501

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 3/3

7:16 pm-1:40 pm

2 stops18h 24m

Panama City Tocumen Intl

Tue 3/10

3:10 pm-10:41 am

2 stops18h 31m

$501

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Mon 3/9

6:11 pm-12:40 pm

2 stops19h 29m

Panama City Tocumen Intl

Sun 5/3

1:49 pm-12:29 pm

2 stops21h 40m

$506

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 5/2

6:33 pm-12:46 pm

1 stop19h 13m

Panama City Tocumen Intl

Sat 5/9

1:49 pm-12:11 pm

2 stops21h 22m

$511

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sun 4/12

6:00 am-1:03 pm

1 stop8h 03m

$236

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sun 3/15

4:24 pm-12:40 pm

2 stops21h 16m

$241

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sun 4/12

4:24 pm-12:46 pm

2 stops21h 22m

$241

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sun 4/12

6:37 pm-9:15 am

3 stops39h 38m

$256

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sun 3/15

9:45 pm-2:00 pm

3 stops41h 15m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 11 results
1
2

Best time to book a flight from Wilmington to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to Panama
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 6, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,246 reviews

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,246 reviews
American Airlines
7.2
Good
11,246 reviews

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Wilmington to Panama?

    Most people fly from Wilmington New Hanover County (ILM) if they book a flight from Wilmington to Panama. Wilmington New Hanover County is conveniently located just 4.3 mi from Wilmington’s city center.

  • How long is the flight from Wilmington to Panama?

    There are many flights that can get you from Wilmington to Panama in 7h 10m. Fly via American Airlines to get the fastest option. There are 1742 mi between Wilmington and Panama.

  • Can I find deals for flights from Wilmington to Panama that include hotel bookings?

    Yes. In addition to deals on Wilmington to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Panama.

  • Can I find deals for business class flights from Wilmington to Panama?

    Yes. Cheapflights offers flight deals from Wilmington to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Wilmington to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Wilmington to Panama

Discover the top airline that operate flights from Wilmington to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$491Average$605FlexibilityNo cancel feeOn-time71%

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