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$456+ Cheap flights from Wilmington (ILM) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — PTY
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from Wilmington to Panama

Cheapest flights from Wilmington to Panama
Explore the most affordable flight options available from Wilmington to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amILM - PTY
1 stop9h 42mAmerican Airlines
Sun 12/212:53 pmPTY - ILM
1 stop9h 54mAmerican Airlines
Deal found 11/1$481
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:00 amILM - PTY
1 stop7h 43mAmerican Airlines
Wed 12/32:50 pmPTY - ILM
1 stop9h 09mAmerican Airlines
Deal found 11/2$496
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:19 pmILM - PTY
2 stops18h 28mAmerican Airlines
Sat 12/204:55 pmPTY - ILM
1 stop7h 52mAmerican Airlines
Deal found 11/1$500
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amILM - PTY
1 stop9h 42mAmerican Airlines
Tue 1/64:31 pmPTY - ILM
1 stop7h 26mAmerican Airlines
Deal found 11/2$506
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:00 amILM - PTY
1 stop7h 43mAmerican Airlines
Sat 12/62:50 pmPTY - ILM
1 stop9h 09mAmerican Airlines
Deal found 11/1$636
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/234:46 pmILM - PTY
1 stop17h 47mMultiple Airlines
Fri 12/52:55 amPTY - ILM
2 stops29h 45mMultiple Airlines
Deal found 11/1$1,016
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:10 pmILM - PTY
1 stop18h 12mMultiple Airlines
Sat 12/202:55 amPTY - ILM
2 stops17h 37mMultiple Airlines
Deal found 11/1$1,265

Cheap flight deals from Wilmington to Panama

Keep the following information in mind while searching for Wilmington to Panama flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$456
(American Airlines)

Popular in

June

Cheapest in

August

Average price

$727
Provider with most accurate pricing for Wilmington New Hanover County-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilmington New Hanover County-Panama City Tocumen Intl flights.
Search Deals
From Wilmington New Hanover County to Panama
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($107 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Wilmington to Panama that are best for you.

Fly from

Wilmington

Fly to

Panama

Route

Depart

Return

Price

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Fri 4/17

6:00 am-12:15 pm

1 stop7h 15m

Panama City Tocumen Intl

Mon 4/27

1:55 pm-11:00 pm

1 stop8h 05m

$456

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 1/17

6:00 am-3:52 pm

1 stop9h 52m

Panama City Tocumen Intl

Sun 2/15

2:52 pm-11:59 pm

1 stop9h 07m

$481

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Thu 12/11

6:00 am-3:42 pm

1 stop9h 42m

Panama City Tocumen Intl

Sun 12/21

2:53 pm-12:47 am

1 stop9h 54m

$481

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Best time to book a flight from Wilmington to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to Panama

What is the cheapest time of day to fly from ILM to PA?

Find hourly flight availability from Wilmington to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

One of the essential ways to save on airfare from Wilmington to Panama is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 58% on airfare.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 3, 2025.
Read reviews from past customers who have flown American Airlines from Wilmington to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,037 reviews

Crew

8.0

Overall

7.2

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,037 reviews
American Airlines
7.2
Good
11,037 reviews

Crew

8.0

Overall

7.2

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Wilmington to Panama?

    Most people fly from Wilmington New Hanover County (ILM) if they book a flight from Wilmington to Panama. Wilmington New Hanover County is conveniently located just 4.3 mi from Wilmington’s city center.

  • How long is the flight from Wilmington to Panama?

    There are many flights that can get you from Wilmington to Panama in 7h 15m. Fly via American Airlines to get the fastest option. There are 1742 mi between Wilmington and Panama.

  • Can I find deals for flights from Wilmington to Panama that include hotel bookings?

    Yes. In addition to deals on Wilmington to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Panama.

  • Can I find deals for business class flights from Wilmington to Panama?

    Yes. Cheapflights offers flight deals from Wilmington to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Wilmington to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Wilmington to Panama

Discover the top airline that operate flights from Wilmington to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$496Average$621FlexibilityNo cancel feeOn-time71%

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