HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$209+ Cheap flights from San Francisco (SFO) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Francisco to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Francisco to Panama

Keep the following information in mind while searching for San Francisco to Panama flight deals. Data was last updated July 29, 2025.

Round-trip from

$499
(Cheapflightsfares)

One-way from

$209
(Justfly.com)

Popular in

December

Cheapest in

August

Average price

$616

Good round-trip deal

$506 or less

Good one-way deal

$290 or less
From San Francisco to Panama
Search Deals
One-way flight from San Francisco to Panama
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($118 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals
Price to beat on a round-trip flight from San Francisco to Panama.
Search Deals
Price to beat on a one-way flight from San Francisco to Panama.
Search Deals

Find flight deals from San Francisco to Panama

Cheapest flights from San Francisco to Panama
Explore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/52:20 pmSFO - PTY
1 stop18h 05mAvianca
Mon 9/158:10 pmPTY - SFO
1 stop18h 25mAvianca
Deal found 7/28$499
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:43 amSFO - PTY
1 stop13h 24mUnited Airlines
Sun 12/143:35 pmPTY - SFO
Nonstop7h 54mUnited Airlines
Deal found 7/29$508
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/49:38 pmSFO - PTY
1 stop13h 17mDelta
Fri 10/172:21 pmPTY - SFO
1 stop11h 35mDelta
Deal found 7/26$518
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:45 pmSFO - PTY
2 stops16h 46mAmerican Airlines
Thu 9/253:31 pmPTY - SFO
1 stop23h 34mAmerican Airlines
Deal found 7/28$520
This Copa Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/261:30 amSFO - PTY
Nonstop7h 11mCopa Airlines
Thu 9/45:50 pmPTY - SFO
Nonstop7h 35mCopa Airlines
Deal found 7/28$534
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/147:10 amSFO - PTY
1 stop20h 15mMultiple Airlines
Thu 9/1810:05 pmPTY - SFO
2 stops16h 30mMultiple Airlines
Deal found 7/28$558
This Copa Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/181:30 amSFO - DAV
1 stop14h 02mCopa Airlines
Thu 8/289:44 amDAV - SFO
1 stop15h 55mCopa Airlines
Deal found 7/28$709
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1910:55 amSFO - DAV
1 stop20h 04mUnited Airlines
Thu 8/289:44 amDAV - SFO
2 stops16h 15mUnited Airlines
Deal found 7/28$1,052
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/52:20 pmSFO - DAV
2 stops24h 55mMultiple Airlines
Thu 8/148:30 amDAV - SFO
1 stop17h 09mMultiple Airlines
Deal found 7/28$1,233

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.

Fly from

San Francisco

Fly to

Panama

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 8/12

2:20 pm-10:25 am

1 stop18h 05m

Panama City Tocumen Intl

Sun 8/17

3:20 am-10:45 pm

2 stops21h 25m

$499

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sat 10/4

9:38 pm-12:55 pm

1 stop13h 17m

Panama City Tocumen Intl

Fri 10/17

2:21 pm-11:56 pm

1 stop11h 35m

$518

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Fri 9/12

10:55 am-8:10 pm

Nonstop7h 15m

Panama City Tocumen Intl

Fri 9/19

3:35 pm-9:10 pm

Nonstop7h 35m

$519

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 9/18

7:45 pm-2:31 pm

2 stops16h 46m

Panama City Tocumen Intl

Thu 9/25

3:31 pm-1:05 pm

1 stop23h 34m

$520

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 8/26

1:30 am-10:41 am

Nonstop7h 11m

Panama City Tocumen Intl

Thu 9/4

5:50 pm-11:25 pm

Nonstop7h 35m

$534

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sun 9/14

7:10 am-5:25 am

1 stop20h 15m

Panama City Tocumen Intl

Thu 9/18

10:05 pm-12:35 pm

2 stops16h 30m

$558

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

Mon 8/18

1:30 am-5:32 pm

1 stop14h 02m

David Enrique Malek

Thu 8/28

9:44 am-11:39 pm

1 stop15h 55m

$709

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

Tue 8/19

10:55 am-8:59 am

1 stop20h 04m

David Enrique Malek

Thu 8/28

9:44 am-11:59 pm

2 stops16h 15m

$1,052

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

Fri 12/19

11:15 pm-5:24 pm

2 stops15h 09m

David Enrique Malek

Mon 12/29

9:50 am-12:00 pm

2 stops29h 10m

$2,282

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 8/12

12:05 am-10:25 am

1 stop8h 20m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 14 results
1
2

Best time to book a flight from San Francisco to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama

What is the cheapest month to book a flight from San Francisco to Panama?

Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to PA?

Find hourly flight availability from San Francisco to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

When flying from San Francisco to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 12% versus a flight in the morning.

What is the cheapest day to fly from San Francisco to Panama?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Panama. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Panama flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Panama

Explore weekly flight availability from San Francisco to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 29, 2025.

The most flights from SFO to PA0 are scheduled on a Monday (5 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 29, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from San Francisco to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,899 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,386 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Panama?

    If you book a flight to Panama from San Francisco, you will be flying from San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.

  • How popular is this San Francisco to Panama flight route?

    Within the past month, 128 users have taken a look at flights from San Francisco to Panama.

  • What are the cheapest airlines to fly from San Francisco to Panama one-way?

    $209 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on United Airlines and Copa Airlines, with prices starting from $400 and $604, respectively.

  • What are the most popular routes from San Francisco to Panama?

    The most popular route from San Francisco to Panama is San Francisco - Panama City Tocumen Intl. You may also consider San Francisco - David Enrique Malek or San Francisco - Bocas Del Toro.

  • What are the most reliable airlines from San Francisco to Panama?

    No one likes to see their flight delayed. When booking a flight from San Francisco to Panama consider choosing EVA Air (95%), Copa Airlines (91%) or United Airlines (86%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from San Francisco to Panama?

    The cheapest flight price from San Francisco to Panama is $209. On average you can expect to pay $1,422. The most popular route, (San Francisco - Panama City Tocumen Intl), can usually be booked for $479.

  • Can I find deals for flights from San Francisco to Panama that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama.

  • Can I find deals for business class flights from San Francisco to Panama?

    Yes. Cheapflights offers flight deals from San Francisco to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama?

    Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to San Salvador flights
Los Angeles to Guatemala City flights
Los Angeles to San José flights
Los Angeles to Panama City flights
Los Angeles to Philip S.W.Goldson flights
Ontario to San Salvador flights
San Francisco to San José flights
San Francisco to Panama City flights
San Francisco to San Salvador flights
Los Angeles to Liberia flights
San Francisco to Guatemala City flights
Ontario to Guatemala City flights
Ontario to San José flights
Los Angeles to Managua flights
San Francisco to Liberia flights
Oakland to San José flights
San Francisco to Managua flights
Reno to San José flights
Burbank to San Salvador flights
Ontario to Liberia flights
San Francisco to Philip S.W.Goldson flights
Burbank to Guatemala City flights
San Diego to San José flights
Oakland to San Salvador flights
Ontario to Panama City flights
San Jose to San José flights
Las Vegas to San José flights
Los Angeles to San Pedro Sula flights
Las Vegas to San Salvador flights
Ontario to Philip S.W.Goldson flights
San Diego to Panama City flights
San Diego to Managua flights
Burbank to San José flights
Sacramento to San José flights
San Diego to Liberia flights
Ontario to Managua flights
Las Vegas to Panama City flights
San Jose to Liberia flights
San Diego to Philip S.W.Goldson flights
Oakland to Guatemala City flights
Ontario to San Pedro Sula flights
San Jose to Philip S.W.Goldson flights
Sacramento to Liberia flights
Las Vegas to Philip S.W.Goldson flights
San Jose to Panama City flights
Santa Ana to San José flights
San Diego to Guatemala City flights
Las Vegas to Guatemala City flights
Sacramento to San Salvador flights
San Francisco to San Pedro Sula flights

Top 5 airlines flying from San Francisco to Panama

Discover the top 5 airlines that operate flights from San Francisco to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$387Average$611FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$400Average$611FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$503Average$675FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$539Average$712FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$544Average$590FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.