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$210+ Cheap flights from San Francisco (SFO) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Aug 16 — Aug 231
Sat 8/16
Sat 8/23
1 adult, Economy
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Cheap flight deals from San Francisco to Panama

Keep the following information in mind while searching for San Francisco to Panama flight deals. Data was last updated August 11, 2025.

Round-trip from

$500
(Cheapflightsfares)

One-way from

$210
(Cheapflightsfares)

Popular in

December

Cheapest in

August

Average price

$593

Good round-trip deal

$496 or less

Good one-way deal

$243 or less
From San Francisco to Panama
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One-way flight from San Francisco to Panama
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Highest demand for flights based on searches. 13% potential increase in price ($102 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from San Francisco to Panama.
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Price to beat on a one-way flight from San Francisco to Panama.
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Find flight deals from San Francisco to Panama

Cheapest flights from San Francisco to Panama
Explore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/212:20 pmSFO - PTY
1 stop18h 05mAvianca
Sat 8/303:20 amPTY - SFO
2 stops21h 25mAvianca
Deal found 8/10$500
This Priceline deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/102:20 pmSFO - PTY
2 stops28h 50mAvianca
Wed 9/175:25 pmPTY - SFO
2 stops21h 10mAvianca
Deal found 8/10$501
This Priceline deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/111:35 amSFO - PTY
2 stops28h 15mAvianca
Sun 11/162:55 amPTY - SFO
2 stops21h 55mAvianca
Deal found 8/9$502
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:45 amSFO - PTY
Nonstop7h 04mUnited Airlines
Thu 11/273:35 pmPTY - SFO
Nonstop7h 54mUnited Airlines
Deal found 8/10$504
This Avianca deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1912:05 amSFO - PTY
1 stop32h 20mAvianca
Sat 9/279:55 amPTY - SFO
2 stops14h 50mAvianca
Deal found 8/9$506
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2112:43 amSFO - PTY
1 stop15h 54mUnited Airlines
Tue 11/253:35 pmPTY - SFO
Nonstop7h 54mUnited Airlines
Deal found 8/9$508
This Cheapflightsfares deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1112:05 amSFO - PTY
2 stops19h 05mAvianca
Sun 8/173:20 amPTY - SFO
2 stops21h 25mAvianca
Deal found 8/11$511
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1512:05 amSFO - PTY
1 stop12h 40mAvianca
Sun 10/193:40 pmPTY - SFO
1 stop9h 05mAvianca
Deal found 8/10$513
This Avianca deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:15 pmSFO - PTY
1 stop8h 10mAvianca
Sun 12/148:05 pmPTY - SFO
1 stop18h 55mAvianca
Deal found 8/9$516
This Cheapflightsfares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/142:30 amSFO - PTY
1 stop10h 15mAvianca
Mon 8/183:25 amPTY - SFO
2 stops21h 20mAvianca
Deal found 8/9$518
This Copa Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/91:30 amSFO - DAV
1 stop13h 59mCopa Airlines
Sat 10/119:44 amDAV - SFO
1 stop15h 55mCopa Airlines
Deal found 8/11$544
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/109:04 amSFO - DAV
2 stops21h 54mMultiple Airlines
Sat 10/116:17 pmDAV - SFO
1 stop31h 22mMultiple Airlines
Deal found 8/10$655

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.

Fly from

San Francisco

Fly to

Panama

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 8/21

2:20 pm-10:25 am

1 stop18h 05m

Panama City Tocumen Intl

Sat 8/30

3:20 am-10:45 pm

2 stops21h 25m

$500

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 9/10

2:20 pm-9:10 pm

2 stops28h 50m

Panama City Tocumen Intl

Wed 9/17

5:25 pm-12:35 pm

2 stops21h 10m

$501

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 11/11

1:35 am-8:50 am

2 stops28h 15m

Panama City Tocumen Intl

Sun 11/16

2:55 am-9:50 pm

2 stops21h 55m

$502

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 1/22

1:20 pm-10:25 am

1 stop18h 05m

Panama City Tocumen Intl

Mon 1/26

8:05 pm-12:00 pm

1 stop18h 55m

$504

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Fri 1/16

11:15 pm-9:00 pm

2 stops18h 45m

Panama City Tocumen Intl

Thu 1/22

3:19 am-9:55 pm

2 stops21h 36m

$506

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 10/21

12:43 am-6:37 pm

1 stop15h 54m

Panama City Tocumen Intl

Tue 11/25

3:35 pm-8:29 pm

Nonstop7h 54m

$508

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sat 9/20

2:20 pm-4:30 pm

2 stops24h 10m

Panama City Tocumen Intl

Sat 9/27

10:05 pm-10:45 pm

2 stops26h 40m

$512

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 10/15

12:05 am-2:45 pm

1 stop12h 40m

Panama City Tocumen Intl

Sun 10/19

3:40 pm-10:45 pm

1 stop9h 05m

$513

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 11/20

8:45 am-6:49 pm

Nonstop7h 04m

Panama City Tocumen Intl

Thu 11/27

8:55 am-7:25 pm

1 stop13h 30m

$514

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Fri 12/5

11:15 pm-10:25 am

1 stop8h 10m

Panama City Tocumen Intl

Sun 12/14

8:05 pm-12:00 pm

1 stop18h 55m

$516

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/10

Showing 1-10 of 36 results
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Best time to book a flight from San Francisco to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama

What is the cheapest month to book a flight from San Francisco to Panama?

Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to PA?

Find hourly flight availability from San Francisco to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 11, 2025.

When flying from San Francisco to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 10% versus a flight in the morning.

What is the cheapest day to fly from San Francisco to Panama?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Panama. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Panama flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Panama

Explore weekly flight availability from San Francisco to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 11, 2025.

The most flights from SFO to PA0 are scheduled on a Monday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (5 on average).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 11, 2025.
Read reviews from past customers who have flown Copa Airlines, United Airlines, and Avianca from San Francisco to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,505 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.5

Food

6.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Copa Airlines
7.5
Good
1,505 reviews
Copa Airlines
7.5
Good
1,505 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.5

Food

6.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
United Airlines
7.4
Good
8,920 reviews
Copa Airlines
7.5
Good
1,505 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.5

Food

6.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Avianca
6.7
Okay
2,397 reviews
Copa Airlines
7.5
Good
1,505 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.5

Food

6.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Panama?

    If you book a flight to Panama from San Francisco, you will be flying from San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.

  • How popular is this San Francisco to Panama flight route?

    Within the past month, 117 users have taken a look at flights from San Francisco to Panama.

  • What are the most popular routes from San Francisco to Panama?

    The most popular route from San Francisco to Panama is San Francisco - Panama City Tocumen Intl. You may also consider San Francisco - David Enrique Malek or San Francisco - Bocas Del Toro.

  • What are the most reliable airlines from San Francisco to Panama?

    No one likes to see their flight delayed. When booking a flight from San Francisco to Panama consider choosing EVA Air (87%), Copa Airlines (78%) or United Airlines (78%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from San Francisco to Panama?

    The cheapest flight price from San Francisco to Panama is $209. On average you can expect to pay $947. The most popular route, (San Francisco - Panama City Tocumen Intl), can usually be booked for $501.

  • Can I find deals for flights from San Francisco to Panama that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama.

  • Can I find deals for business class flights from San Francisco to Panama?

    Yes. Cheapflights offers flight deals from San Francisco to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama?

    Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Francisco to Panama

Discover the top 5 airlines that operate flights from San Francisco to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$387Average$611FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$400Average$607FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$503Average$675FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$536Average$705FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$544Average$590FlexibilityNo cancel feeOn-time71%

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