$200+ Cheap flights from San Francisco (SFO) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from San Francisco to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Panama
Cheapest flights from San Francisco to PanamaExplore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 5, 2026.
Explore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 5, 2026.
This Avianca deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Priceline deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Priceline deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Priceline deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Priceline deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Trip.com deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from San Francisco to Panama
Keep the following information in mind while searching for San Francisco to Panama flight deals. Data was last updated January 5, 2026.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $562 (Avianca) |
One-way from | $200 (Super.com) |
Popular in | December |
Cheapest in | October |
Average price | $658 |
Good round-trip deal | $622 or less |
Good one-way deal | $320 or less |
Cheapflights Fare Finder
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Thu 3/26
12:10 am-4:55 pm
2 stops14h 45m
Panama City Tocumen Intl
Thu 4/2
3:40 pm-11:55 pm
1 stop10h 15m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Mon 2/2
11:10 pm-4:55 pm
2 stops14h 45m
Panama City Tocumen Intl
Sun 2/15
3:50 pm-7:31 am
2 stops18h 41m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Mon 2/2
11:10 pm-10:30 am
1 stop8h 20m
Panama City Tocumen Intl
Sun 2/15
7:50 pm-12:00 pm
1 stop19h 10m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Tue 2/24
12:42 am-10:46 am
Nonstop7h 04m
Panama City Tocumen Intl
Wed 3/18
5:51 pm-11:40 pm
Nonstop7h 49m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Tue 3/10
1:54 am-10:46 am
Nonstop6h 52m
Panama City Tocumen Intl
Wed 3/25
5:51 pm-11:40 pm
Nonstop7h 49m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sun 4/26
1:23 am-10:27 am
Nonstop7h 04m
Panama City Tocumen Intl
Fri 5/1
5:55 pm-11:40 pm
Nonstop7h 45m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Mon 3/23
1:54 am-10:46 am
Nonstop6h 52m
Panama City Tocumen Intl
Tue 3/31
5:51 pm-11:40 pm
Nonstop7h 49m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Mon 4/27
1:23 am-10:27 am
Nonstop7h 04m
Panama City Tocumen Intl
Sun 5/3
5:55 pm-11:40 pm
Nonstop7h 45m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Tue 3/31
1:23 am-10:27 am
Nonstop7h 04m
Panama City Tocumen Intl
Mon 4/20
5:53 pm-11:40 pm
Nonstop7h 47m
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Thu 3/5
12:54 am-10:46 am
Nonstop6h 52m
Panama City Tocumen Intl
Fri 3/13
5:51 pm-11:40 pm
Nonstop7h 49m
Best time to book a flight from San Francisco to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Francisco with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama
What is the cheapest month to book a flight from San Francisco to Panama?
Currently, June is the cheapest month in which you can book a flight from San Francisco to Panama (average of $222). Flying from San Francisco to Panama in November is currently the most expensive (average of $502). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to PA?
Find hourly flight availability from San Francisco to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 5, 2026.
When flying from San Francisco to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from San Francisco to Panama
Explore weekly flight availability from San Francisco to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 5, 2026.
The most flights from SFO to PA0 are scheduled on a Monday (5 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (1 on average).
How often are flights from San Francisco to Panama delayed?
About 8% of weekly flights between San Francisco and Panama have experienced delays in the past year, with the average delay time being 142 minutes.
What is the most punctual flight time for San Francisco to Panama flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on San Francisco to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 6% of flights being delayed.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 5, 2026.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from San Francisco to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
Overall
Entertainment
Boarding
Crew
Comfort
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Overall
Entertainment
Boarding
Crew
Comfort
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Overall
Entertainment
Boarding
Crew
Comfort
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Overall
Entertainment
Boarding
Crew
Comfort
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Overall
Entertainment
Boarding
Crew
Comfort
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Overall
Entertainment
Boarding
Crew
Comfort
Reviews
Aaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Francisco to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from San Francisco to Panama
Discover the top 5 airlines that operate flights from San Francisco to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$387 | Average$527 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$399 | Average$570 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$503 | Average$728 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$533 | Average$733 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$588 | Average$895 | FlexibilityNo cancel fee | On-time71% |