$202+ Cheap flights from San Francisco (SFO) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Oct 26 — Nov 21
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Panama
Keep the following information in mind while searching for San Francisco to Panama flight deals. Data was last updated September 26, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $484 (FlightHub) |
One-way from | $207 (Mytrip) |
Popular in | December |
Cheapest in | August |
Average price | $668 |
Good round-trip deal | $519 or less |
Good one-way deal | $239 or less |
Find flight deals from San Francisco to Panama
Cheapest flights from San Francisco to PanamaExplore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2025.
Explore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2025.
This Priceline deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:35 amSFO - PTY
1 stop14h 20mAvianca
Fri 11/142:55 amPTY - SFO
2 stops21h 55mAvianca
Deal found 9/24![Avianca logo]()
$484
This Cheapflightsfares deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/162:20 pmSFO - PTY
2 stops17h 50mAvianca
Sat 10/183:20 amPTY - SFO
2 stops21h 25mAvianca
Deal found 9/25![Avianca logo]()
$485
This Mytrip deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/102:20 pmSFO - PTY
1 stop18h 05mAvianca
Sat 10/1810:05 pmPTY - SFO
2 stops16h 30mAvianca
Deal found 9/23![Avianca logo]()
$488
This Cheapflightsfares deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/222:20 pmSFO - PTY
1 stop18h 05mAvianca
Mon 11/242:55 pmPTY - SFO
2 stops24h 05mAvianca
Deal found 9/26![Avianca logo]()
$489
This Priceline deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:35 amSFO - PTY
1 stop14h 20mAvianca
Sat 11/152:55 amPTY - SFO
2 stops21h 55mAvianca
Deal found 9/25![Avianca logo]()
$494
This Cheapflightsfares deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/102:20 pmSFO - PTY
2 stops28h 50mAvianca
Thu 10/163:20 amPTY - SFO
2 stops21h 25mAvianca
Deal found 9/24![Avianca logo]()
$496
This Cheapflightsfares deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/211:10 pmSFO - PTY
2 stops22h 30mAvianca
Tue 12/99:45 amPTY - SFO
2 stops16h 35mAvianca
Deal found 9/24![Avianca logo]()
$500
This Cheapflightsfares deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/291:35 amSFO - PTY
2 stops20h 25mAvianca
Wed 12/102:55 amPTY - SFO
2 stops21h 55mAvianca
Deal found 9/24![Avianca logo]()
$501
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:36 amSFO - DAV
1 stop13h 48mCopa Airlines
Sat 11/159:53 amDAV - SFO
1 stop16h 24mCopa Airlines
Deal found 9/24![Copa Airlines logo]()
$987
This KAYAK deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:36 amSFO - DAV
1 stop16h 04mCopa Airlines
Mon 12/88:32 amDAV - SFO
1 stop17h 45mCopa Airlines
Deal found 9/24![Copa Airlines logo]()
$1,049
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:45 amSFO - DAV
1 stop29h 39mUnited Airlines
Mon 12/89:50 amDAV - SFO
1 stop13h 39mUnited Airlines
Deal found 9/24![United Airlines logo]()
$1,234
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/88:45 amSFO - DAV
1 stop29h 39mUnited Airlines
Sat 11/159:53 amDAV - SFO
1 stop13h 36mUnited Airlines
Deal found 9/24![United Airlines logo]()
$1,329
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 26, 2025.
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.
Fly from
San Francisco
Fly to
Panama
Route
Depart
Return
Price
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Thu 1/29
11:10 pm-12:40 am
2 stops22h 30m
Panama City Tocumen Intl
Sun 2/1
2:55 pm-12:00 pm
2 stops24h 05m
$484
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Thu 10/23
2:20 pm-10:25 am
1 stop18h 05m
Panama City Tocumen Intl
Sun 10/26
7:50 pm-1:00 pm
1 stop19h 10m
$499
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Wed 10/15
12:05 am-12:10 am
2 stops22h 05m
Panama City Tocumen Intl
Sat 10/18
3:20 am-10:45 pm
2 stops21h 25m
$507
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Tue 2/10
12:42 am-10:46 am
Nonstop7h 04m
Panama City Tocumen Intl
Wed 3/4
6:27 pm-11:16 pm
Nonstop7h 49m
$637
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Wed 1/28
12:42 am-10:46 am
Nonstop7h 04m
Panama City Tocumen Intl
Sun 2/1
6:27 pm-11:20 pm
Nonstop7h 53m
$637
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Fri 11/14
12:36 am-10:46 am
Nonstop7h 10m
Panama City Tocumen Intl
Sat 11/22
6:27 pm-11:17 pm
Nonstop7h 50m
$637
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sun 3/15
1:54 am-10:46 am
Nonstop6h 52m
Panama City Tocumen Intl
Tue 3/31
5:51 pm-11:40 pm
Nonstop7h 49m
$637
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Tue 2/17
12:42 am-10:46 am
Nonstop7h 04m
Panama City Tocumen Intl
Sat 2/28
6:27 pm-11:20 pm
Nonstop7h 53m
$637
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Mon 11/24
8:45 am-6:49 pm
Nonstop7h 04m
Panama City Tocumen Intl
Mon 12/1
3:35 pm-8:29 pm
Nonstop7h 54m
$659
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Fri 12/12
8:45 am-6:49 pm
Nonstop7h 04m
Panama City Tocumen Intl
Fri 12/19
3:35 pm-8:29 pm
Nonstop7h 54m
$659
Showing 1-10 of 33 results
Best time to book a flight from San Francisco to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama
What is the cheapest month to book a flight from San Francisco to Panama?
Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to PA?
Find hourly flight availability from San Francisco to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 26, 2025.
When flying from San Francisco to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 11% versus a flight at noon.
What is the cheapest day to fly from San Francisco to Panama?
Use this chart to determine the cheapest time to fly round-trip from San Francisco to Panama. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their San Francisco to Panama flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from San Francisco to Panama
Explore weekly flight availability from San Francisco to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 26, 2025.
The most flights from SFO to PA0 are scheduled on a Monday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (5 on average).
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 26, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from San Francisco to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Crew
8.5
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Crew
8.5
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Crew
8.5
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Crew
8.5
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Crew
8.5
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.9
Crew
8.5
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Francisco to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from San Francisco to Panama
Discover the top 5 airlines that operate flights from San Francisco to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 26, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$387 | Average$547 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$430 | Average$580 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$503 | Average$730 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$533 | Average$700 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$544 | Average$588 | FlexibilityNo cancel fee | On-time71% |