HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$175+ Cheap flights from San Diego (SAN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
ene. 14 — ene. 211
mié. 1/14
mié. 1/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Diego to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Diego to Panama

Cheapest flights from San Diego to Panama
Explore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 15, 2025.

This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/285:10 pmSAN - PTY
1 stop18h 35mUnited Airlines
mié. 12/314:41 pmPTY - SAN
2 stops27h 53mUnited Airlines
Deal found 12/14$453
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/263:00 pmSAN - PTY
1 stop20h 45mUnited Airlines
mié. 12/314:41 pmPTY - SAN
2 stops27h 53mUnited Airlines
Deal found 12/14$489
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/2411:00 amSAN - PTY
2 stops24h 45mUnited Airlines
mié. 12/314:41 pmPTY - SAN
2 stops27h 53mUnited Airlines
Deal found 12/14$519
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/295:10 pmSAN - PTY
1 stop18h 35mUnited Airlines
lun. 2/238:55 amPTY - SAN
1 stop10h 43mUnited Airlines
Deal found 12/13$524
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/263:00 pmSAN - PTY
1 stop20h 45mUnited Airlines
dom. 12/284:41 pmPTY - SAN
2 stops25h 20mUnited Airlines
Deal found 12/14$530
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/318:12 pmSAN - DAV
1 stop9h 58mCopa Airlines
sáb. 1/106:16 pmDAV - SAN
1 stop26h 25mCopa Airlines
Deal found 12/15$1,024
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/318:12 pmSAN - DAV
1 stop9h 58mMultiple Airlines
mié. 1/78:20 pmDAV - SAN
2 stops25h 31mMultiple Airlines
Deal found 12/15$1,084
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/318:12 pmSAN - DAV
1 stop9h 58mMultiple Airlines
mar. 1/68:32 amDAV - SAN
2 stops38h 14mMultiple Airlines
Deal found 12/15$1,112
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/305:10 pmSAN - DAV
2 stops37h 00mUnited Airlines
sáb. 2/79:48 amDAV - SAN
2 stops29h 00mUnited Airlines
Deal found 12/15$1,124
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/318:12 pmSAN - DAV
1 stop9h 58mMultiple Airlines
sáb. 1/106:16 pmDAV - SAN
2 stops27h 35mMultiple Airlines
Deal found 12/15$1,146
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/318:12 pmSAN - DAV
1 stop9h 58mMultiple Airlines
jue. 1/88:32 amDAV - SAN
2 stops30h 11mMultiple Airlines
Deal found 12/15$1,184
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/295:10 pmSAN - DAV
2 stops36h 59mUnited Airlines
mié. 1/79:50 amDAV - SAN
2 stops39h 43mUnited Airlines
Deal found 12/15$1,204

Find flight deals from San Diego to Panama

Keep the following information in mind while searching for San Diego to Panama flight deals. Data was last updated diciembre 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$409
(Copa Airlines)

One-way from

$175
(Copa Airlines)

Popular in

January

Cheapest in

September

Average price

$623

Good round-trip deal

$355 or less

Good one-way deal

$209 or less
Provider with most accurate pricing for San Diego-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Panama City Tocumen Intl flights.
Search Deals
From San Diego to Panama
Search Deals
One-way flight from San Diego to Panama
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($104 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from San Diego to Panama.
Search Deals
Price to beat on a one-way flight from San Diego to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

San Diego

Fly to

Panama

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mié. 1/21

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

lun. 1/26

1:45 pm-5:41 pm

Nonstop6h 56m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

vie. 1/16

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

lun. 1/19

1:45 pm-5:41 pm

Nonstop6h 56m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mar. 1/6

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

mié. 1/14

1:45 pm-5:41 pm

Nonstop6h 56m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

lun. 1/19

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

mié. 1/21

4:41 pm-10:27 am

2 stops20h 46m

$428

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mar. 1/6

4:00 pm-5:07 pm

2 stops22h 07m

Panama City Tocumen Intl

mié. 1/14

4:41 pm-10:27 am

2 stops20h 46m

$428

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mié. 1/7

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

mié. 1/21

4:41 pm-4:36 pm

1 stop26h 55m

$433

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

vie. 1/16

11:08 am-2:45 pm

2 stops24h 37m

Panama City Tocumen Intl

lun. 1/19

4:41 pm-10:27 am

2 stops20h 46m

$494

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

dom. 12/28

5:10 pm-2:45 pm

1 stop18h 35m

Panama City Tocumen Intl

mié. 12/31

4:41 pm-5:34 pm

2 stops27h 53m

$519

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mar. 12/23

5:10 pm-7:38 pm

1 stop23h 28m

Panama City Tocumen Intl

jue. 2/19

8:55 am-4:38 pm

1 stop10h 43m

$559

San DiegoDavid

SAN - DAV

SANDAV

San Diego

dom. 4/12

9:18 pm-7:43 am

1 stop8h 25m

David Enrique Malek

dom. 4/19

8:32 am-6:30 pm

1 stop11h 58m

$647

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from San Diego to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Panama

What is the cheapest month to book a flight from San Diego to Panama?

Currently, September is the cheapest month in which you can book a flight from San Diego to Panama (average of $200). Flying from San Diego to Panama in April is currently the most expensive (average of $483). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to PA?

Find hourly flight availability from San Diego to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 15, 2025.

One of the essential ways to save on airfare from San Diego to Panama is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 55% on airfare.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated diciembre 15, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from San Diego to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,557 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
9,093 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Panama?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to Panama from San Diego.

  • How popular is this San Diego to Panama flight route?

    The San Diego to Panama flight path was viewed by 13 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from San Diego to Panama?

    A quick flight from San Diego to Panama can take about 6h 04m. Copa Airlines provides one of the quickest options available for as low as $409. There are 2910 mi between San Diego and Panama. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from San Diego to Panama?

    Looking for the cheapest flight from San Diego to Panama? While on average our users pay $968, our data indicates the cheapest price to be $159. The most popular route (San Diego - Panama City Tocumen Intl), is priced around $409.

  • Can I find deals for flights from San Diego to Panama that include hotel bookings?

    Yes. In addition to deals on San Diego to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Panama.

  • Can I find deals for business class flights from San Diego to Panama?

    Yes. Cheapflights offers flight deals from San Diego to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Panama?

    Currently, September is the cheapest month in which you can book a flight from San Diego to Panama (average of $200). Flying from San Diego to Panama in April is currently the most expensive (average of $483). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to San Salvador flights
Los Angeles to Guatemala City flights
Los Angeles to San José flights
San Francisco to San José flights
Los Angeles to Panama City flights
Los Angeles to Liberia flights
San Francisco to Panama City flights
Los Angeles to Philip S.W.Goldson flights
Ontario to San Salvador flights
San Francisco to San Salvador flights
San Francisco to Liberia flights
Ontario to Guatemala City flights
Los Angeles to Managua flights
San Francisco to Guatemala City flights
Ontario to San José flights
San Diego to San José flights
Las Vegas to San Salvador flights
Burbank to San Salvador flights
San Francisco to Philip S.W.Goldson flights
San Francisco to Managua flights
Burbank to Guatemala City flights
Oakland to San José flights
Los Angeles to San Pedro Sula flights
San Diego to Liberia flights
Burbank to San José flights
San Jose to San José flights
San Diego to Panama City flights
Ontario to Philip S.W.Goldson flights
Sacramento to San José flights
Las Vegas to Panama City flights
San Francisco to San Pedro Sula flights
Las Vegas to San José flights
Santa Ana to San José flights
Ontario to Liberia flights
Ontario to Managua flights
Santa Ana to San Salvador flights
Oakland to San Salvador flights
Las Vegas to Guatemala City flights
Ontario to Panama City flights
Sacramento to Philip S.W.Goldson flights
Reno to San Salvador flights
Los Angeles to Coxen Hole flights
Las Vegas to Liberia flights
Ontario to San Pedro Sula flights
Las Vegas to Managua flights
Oakland to Guatemala City flights
San Diego to Philip S.W.Goldson flights
San Jose to Liberia flights
Sacramento to Guatemala City flights
Reno to San José flights

Top 4 airlines flying from San Diego to Panama

Discover the top 4 airlines that operate flights from San Diego to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$334Average$520FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$355Average$607FlexibilityNo cancel feeOn-time69%
DeltaCheapest$355Average$562FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$489Average$723FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.