$230+ Cheap flights from San Diego (SAN) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
May 2 — May 91
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Panama
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to PanamaExplore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
Explore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:18 pm
SAN
- PTY
Nonstop6h 02m
Copa Airlines
Wed 5/61:39 pm
PTY
- SAN
Nonstop6h 51m
Copa Airlines
Deal found 4/1![Copa Airlines logo]()
$570
This Copa Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:18 pm
SAN
- DAV
1 stop8h 25m
Copa Airlines
Fri 4/178:32 am
DAV
- SAN
1 stop11h 58m
Copa Airlines
Deal found 3/28![Copa Airlines logo]()
$590
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:04 pm
SAN
- PTY
2 stops20h 42m
American Airlines
Sun 5/101:49 pm
PTY
- SAN
2 stops23h 24m
American Airlines
Deal found 4/1![American Airlines logo]()
$594
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:59 pm
SAN
- PTY
2 stops18h 56m
Multiple Airlines
Sat 11/143:50 pm
PTY
- SAN
2 stops24h 04m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$618
This eDestinos deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:24 pm
SAN
- PTY
2 stops18h 06m
Multiple Airlines
Thu 9/173:50 pm
PTY
- SAN
2 stops29h 45m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$619
This Expedia deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:25 am
SAN
- PTY
2 stops22h 05m
Multiple Airlines
Wed 4/225:30 am
PTY
- SAN
2 stops16h 11m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$620
This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:00 pm
SAN
- PTY
Nonstop6h 14m
Copa Airlines
Sun 7/52:01 pm
PTY
- SAN
Nonstop6h 29m
Copa Airlines
Deal found 3/30![Copa Airlines logo]()
$636
This Orbitz deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:15 am
SAN
- PTY
2 stops15h 40m
Multiple Airlines
Wed 5/65:30 am
PTY
- SAN
2 stops36h 58m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:16 pm
SAN
- PTY
2 stops21h 30m
American Airlines
Wed 5/61:49 pm
PTY
- SAN
2 stops20h 26m
American Airlines
Deal found 4/1![American Airlines logo]()
$639
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:15 pm
SAN
- PTY
1 stop18h 59m
United Airlines
Mon 6/297:55 am
PTY
- SAN
1 stop13h 55m
United Airlines
Deal found 3/31![United Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:27 pm
SAN
- PTY
2 stops19h 45m
United Airlines
Fri 7/310:00 am
PTY
- SAN
2 stops14h 25m
United Airlines
Deal found 3/31![United Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:00 pm
SAN
- PTY
Nonstop6h 14m
Copa Airlines
Fri 7/242:01 pm
PTY
- SAN
Nonstop6h 29m
Copa Airlines
Deal found 4/1![Copa Airlines logo]()
$656
Best flights from San Diego to PanamaDiscover carefully curated flight deals from San Diego to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
Discover carefully curated flight deals from San Diego to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:18 pm
SAN
- PTY
Nonstop6h 02m
Copa Airlines
Wed 5/61:39 pm
PTY
- SAN
Nonstop6h 51m
Copa Airlines
Deal found 4/1![Copa Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:15 am
SAN
- PTY
1 stop10h 22m
United Airlines
Mon 7/1310:00 am
PTY
- SAN
2 stops15h 54m
United Airlines
Deal found 3/29![United Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:00 pm
SAN
- PTY
Nonstop6h 22m
Copa Airlines
Mon 7/132:01 pm
PTY
- SAN
Nonstop6h 29m
Copa Airlines
Deal found 3/28![Copa Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:15 pm
SAN
- PTY
1 stop18h 59m
United Airlines
Sun 7/53:30 pm
PTY
- SAN
2 stops19h 35m
United Airlines
Deal found 3/30![United Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:00 pm
SAN
- PTY
Nonstop6h 07m
Copa Airlines
Wed 6/32:01 pm
PTY
- SAN
Nonstop6h 39m
Copa Airlines
Deal found 3/29![Copa Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:15 am
SAN
- PTY
1 stop10h 22m
United Airlines
Tue 6/210:00 am
PTY
- SAN
2 stops11h 51m
United Airlines
Deal found 3/29![United Airlines logo]()
$655
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:15 am
SAN
- PTY
1 stop10h 22m
United Airlines
Mon 7/273:30 pm
PTY
- SAN
2 stops20h 38m
United Airlines
Deal found 4/1![United Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:00 pm
SAN
- PTY
Nonstop6h 14m
Copa Airlines
Fri 7/312:01 pm
PTY
- SAN
Nonstop6h 29m
Copa Airlines
Deal found 4/1![Copa Airlines logo]()
$656
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:15 pm
SAN
- PTY
1 stop18h 59m
United Airlines
Wed 6/37:55 am
PTY
- SAN
2 stops13h 56m
United Airlines
Deal found 3/29![United Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:00 pm
SAN
- PTY
Nonstop6h 14m
Copa Airlines
Fri 7/242:01 pm
PTY
- SAN
Nonstop6h 29m
Copa Airlines
Deal found 4/1![Copa Airlines logo]()
$656
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:00 pm
SAN
- PTY
Nonstop6h 22m
Copa Airlines
Sun 7/262:01 pm
PTY
- SAN
Nonstop6h 29m
Copa Airlines
Deal found 3/31![Copa Airlines logo]()
$656
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:00 am
SAN
- DAV
2 stops23h 10m
United Airlines
Tue 9/229:50 am
DAV
- SAN
2 stops33h 56m
United Airlines
Deal found 3/29![United Airlines logo]()
$1,076
This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:42 pm
SAN
- DAV
2 stops20h 35m
Copa Airlines
Sat 8/159:50 am
DAV
- SAN
2 stops12h 05m
Copa Airlines
Deal found 3/30![Copa Airlines logo]()
$1,059
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:15 am
SAN
- DAV
2 stops24h 43m
United Airlines
Wed 5/69:38 am
DAV
- SAN
2 stops37h 47m
United Airlines
Deal found 3/30![United Airlines logo]()
$1,162
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/812:33 pm
SAN
- DAV
2 stops18h 35m
United Airlines
Sat 8/159:50 am
DAV
- SAN
3 stops16h 39m
United Airlines
Deal found 3/30![United Airlines logo]()
$7,895
Last-minute flights from San Diego to PanamaDiscover last-minute flight deals from San Diego to Panama. Data last updated April 2, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Panama. Data last updated April 2, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:18 pm
SAN
- DAV
1 stop8h 25m
Copa Airlines
Fri 4/178:32 am
DAV
- SAN
1 stop11h 58m
Copa Airlines
Deal found 3/28![Copa Airlines logo]()
$590
This Expedia deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:25 am
SAN
- PTY
2 stops22h 05m
Multiple Airlines
Wed 4/225:30 am
PTY
- SAN
2 stops16h 11m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$620
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:18 pm
SAN
- PTY
Nonstop6h 02m
Copa Airlines
Sun 4/191:33 pm
PTY
- SAN
Nonstop6h 57m
Copa Airlines
Deal found 3/31![Copa Airlines logo]()
$670
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:53 pm
SAN
- PTY
1 stop21h 53m
American Airlines
Tue 4/281:49 pm
PTY
- SAN
1 stop10h 39m
American Airlines
Deal found 4/1![American Airlines logo]()
$678
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:18 pm
SAN
- PTY
Nonstop6h 02m
Copa Airlines
Wed 5/61:39 pm
PTY
- SAN
Nonstop6h 51m
Copa Airlines
Deal found 4/1![Copa Airlines logo]()
$570
This Orbitz deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:15 am
SAN
- PTY
2 stops15h 40m
Multiple Airlines
Wed 5/65:30 am
PTY
- SAN
2 stops36h 58m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:16 pm
SAN
- PTY
2 stops21h 30m
American Airlines
Wed 5/61:49 pm
PTY
- SAN
2 stops20h 26m
American Airlines
Deal found 4/1![American Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:04 pm
SAN
- PTY
2 stops20h 42m
American Airlines
Sun 5/101:49 pm
PTY
- SAN
2 stops23h 24m
American Airlines
Deal found 4/1![American Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:15 am
SAN
- DAV
2 stops24h 43m
United Airlines
Wed 5/69:38 am
DAV
- SAN
2 stops37h 47m
United Airlines
Deal found 3/30![United Airlines logo]()
$1,162
This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:00 pm
SAN
- PTY
Nonstop6h 07m
Copa Airlines
Sun 5/241:39 pm
PTY
- SAN
Nonstop6h 51m
Copa Airlines
Deal found 3/30![Copa Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:15 am
SAN
- PTY
1 stop10h 22m
United Airlines
Wed 6/310:00 am
PTY
- SAN
1 stop11h 50m
United Airlines
Deal found 3/29![United Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:15 pm
SAN
- PTY
1 stop18h 59m
United Airlines
Sat 6/273:30 pm
PTY
- SAN
2 stops19h 32m
United Airlines
Deal found 3/31![United Airlines logo]()
$655
One-way flights from San Diego to PanamaSearch for one-way flight options from San Diego to Panama. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
Search for one-way flight options from San Diego to Panama. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:25 am
SAN
- PTY
3 stops24h 50m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:12 pm
SAN
- PTY
3 stops24h 03m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:20 am
SAN
- PTY
3 stops23h 55m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:45 am
SAN
- PTY
3 stops23h 30m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:00 am
SAN
- PTY
3 stops29h 15m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:42 am
SAN
- PTY
3 stops24h 33m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:12 pm
SAN
- PTY
3 stops32h 23m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:00 am
SAN
- PTY
3 stops24h 15m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$280
This Expedia deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:22 pm
SAN
- PTY
2 stops15h 08m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$297
Find flight deals from San Diego to Panama
Keep the following information in mind while searching for San Diego to Panama flight deals. Data was last updated April 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $570 (Copa Airlines) |
One-way from | $230 (Kiwi.com) |
Popular in | January |
Cheapest in | September |
Average price | $658 |
Good round-trip deal | $475 or less |
Good one-way deal | $285 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Wed 4/29
9:18 pm-5:20 am
Nonstop6h 02m
Panama City Tocumen Intl
Wed 5/6
1:39 pm-6:30 pm
Nonstop6h 51m
$570
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Mon 7/6
10:00 pm-6:22 am
Nonstop6h 22m
Panama City Tocumen Intl
Mon 7/13
2:01 pm-6:30 pm
Nonstop6h 29m
$636
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Fri 5/29
10:00 pm-6:07 am
Nonstop6h 07m
Panama City Tocumen Intl
Wed 6/3
2:01 pm-6:40 pm
Nonstop6h 39m
$636
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Mon 7/6
6:15 am-6:37 pm
1 stop10h 22m
Panama City Tocumen Intl
Mon 7/13
10:00 am-11:54 pm
2 stops15h 54m
$655
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Thu 7/2
5:15 pm-2:14 pm
1 stop18h 59m
Panama City Tocumen Intl
Sun 7/5
3:30 pm-9:05 am
2 stops19h 35m
$655
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Fri 5/29
6:15 am-6:37 pm
1 stop10h 22m
Panama City Tocumen Intl
Tue 6/2
10:00 am-7:51 pm
2 stops11h 51m
$655
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Wed 6/24
6:15 am-6:37 pm
1 stop10h 22m
Panama City Tocumen Intl
Mon 7/27
3:30 pm-10:08 am
2 stops20h 38m
$655
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Fri 5/29
5:15 pm-2:14 pm
1 stop18h 59m
Panama City Tocumen Intl
Wed 6/3
7:55 am-7:51 pm
2 stops13h 56m
$655
Quickest round-trip
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Fri 6/26
10:00 pm-6:14 am
Nonstop6h 14m
Panama City Tocumen Intl
Fri 7/31
2:01 pm-6:30 pm
Nonstop6h 29m
$656
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Wed 6/24
10:00 pm-6:14 am
Nonstop6h 14m
Panama City Tocumen Intl
Fri 7/24
2:01 pm-6:30 pm
Nonstop6h 29m
$656
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from San Diego to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Diego with our price prediction graph.
SAN-PTY
SAN-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Panama
SAN-PA0
SAN-PTY
SAN-DAV
What is the cheapest month to book a flight from San Diego to Panama?
Currently, September is the cheapest month in which you can book a flight from San Diego to Panama (average of $200). Flying from San Diego to Panama in April is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to PA?
Find hourly flight availability from San Diego to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2026.
When flying from San Diego to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 2, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andUnited Airlines from San Diego to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Alternative routes for San Diego to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Panama by cabin class
Find flights from San Diego to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Panama flights
Browse other San Diego and Panama flight options. Last updated on April 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Diego to Panama
Discover the top 3 airlines that operate flights from San Diego to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$234 | Average$553 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$243 | Average$561 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$285 | Average$463 | FlexibilityNo cancel fee | On-timeN/A |