Panama

$220+ Cheap flights from San Diego (SAN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
Feb 28 — Mar 71
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Cheap flight deals from San Diego to Panama

Cheapest flights from San Diego to Panama
Explore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:18 pm
SAN
-
PTY
Nonstop6h 02m
Copa Airlines
Wed 4/11:33 pm
PTY
-
SAN
Nonstop6h 57m
Copa Airlines
Deal found 1/28$510
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:41 pm
SAN
-
PTY
2 stops14h 39m
American Airlines
Wed 4/13:51 pm
PTY
-
SAN
2 stops20h 07m
American Airlines
Deal found 1/28$519
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:15 am
SAN
-
PTY
1 stop10h 22m
United Airlines
Mon 4/277:55 am
PTY
-
SAN
1 stop14h 10m
United Airlines
Deal found 1/28$525
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:20 am
SAN
-
PTY
2 stops10h 17m
United Airlines
Sat 5/27:55 am
PTY
-
SAN
1 stop15h 30m
United Airlines
Deal found 1/28$529
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:00 pm
SAN
-
PTY
1 stop19h 14m
Copa Airlines
Sat 4/43:30 pm
PTY
-
SAN
2 stops20h 50m
Copa Airlines
Deal found 1/27$530
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/225:50 pm
SAN
-
PTY
1 stop17h 55m
United Airlines
Tue 3/313:30 pm
PTY
-
SAN
1 stop21h 34m
United Airlines
Deal found 1/27$536
This KAYAK deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:50 pm
SAN
-
PTY
1 stop22h 48m
Copa Airlines
Thu 3/267:55 am
PTY
-
SAN
1 stop14h 23m
Copa Airlines
Deal found 1/29$537
This Orbitz deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:59 pm
SAN
-
PTY
2 stops25h 56m
Multiple Airlines
Mon 4/275:30 am
PTY
-
SAN
2 stops17h 59m
Multiple Airlines
Deal found 1/27$538
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:50 pm
SAN
-
PTY
1 stop22h 48m
United Airlines
Tue 3/313:30 pm
PTY
-
SAN
2 stops20h 24m
United Airlines
Deal found 1/28$541
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:15 am
SAN
-
PTY
2 stops10h 23m
United Airlines
Tue 3/243:41 pm
PTY
-
SAN
2 stops20h 41m
United Airlines
Deal found 1/27$544
This Copa Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:13 pm
SAN
-
DAV
1 stop9h 55m
Copa Airlines
Sun 5/249:55 am
DAV
-
SAN
1 stop10h 35m
Copa Airlines
Deal found 1/26$668
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:50 pm
SAN
-
DAV
2 stops18h 41m
Copa Airlines
Fri 3/208:32 am
DAV
-
SAN
1 stop11h 42m
Copa Airlines
Deal found 1/27$809

Find flight deals from San Diego to Panama

Keep the following information in mind while searching for San Diego to Panama flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$510
(Copa Airlines)

One-way from

$220
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$708

Good round-trip deal

$472 or less

Good one-way deal

$293 or less
Provider with most accurate pricing for San Diego-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for San Diego-Panama City Tocumen Intl flights.
From San Diego to Panama
One-way flight from San Diego to Panama
Highest demand for flights based on searches. 18% potential increase in price ($122 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Average for round-trip flights in January 2026
Price to beat on a round-trip flight from San Diego to Panama.
Price to beat on a one-way flight from San Diego to Panama.

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

San Diego

Fly to

Panama

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 4/12

9:18 pm-5:20 am

Nonstop6h 02m

Panama City Tocumen Intl

Sun 4/19

1:33 pm-6:30 pm

Nonstop6h 57m

$510

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 4/13

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Sun 5/3

10:00 am-8:04 pm

1 stop12h 04m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 4/13

10:30 pm-1:02 pm

1 stop12h 32m

Panama City Tocumen Intl

Tue 4/28

2:27 pm-11:25 pm

1 stop10h 58m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 3/20

5:50 pm-1:45 pm

1 stop17h 55m

Panama City Tocumen Intl

Thu 3/26

7:55 am-6:33 pm

1 stop12h 38m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 4/14

10:30 pm-1:02 pm

1 stop12h 32m

Panama City Tocumen Intl

Wed 4/29

2:27 pm-11:25 pm

1 stop10h 58m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 4/12

5:00 pm-2:14 pm

1 stop19h 14m

Panama City Tocumen Intl

Sun 5/3

7:55 am-5:53 pm

1 stop11h 58m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 4/11

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Sun 4/19

7:55 am-9:26 pm

1 stop15h 31m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 4/10

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Mon 4/27

7:55 am-6:05 pm

1 stop12h 10m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 4/11

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Mon 4/27

7:55 am-8:05 pm

1 stop14h 10m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 4/11

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Sat 5/2

7:55 am-9:25 pm

1 stop15h 30m

$525

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 23 results
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Best time to book a flight from San Diego to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Panama

What is the cheapest month to book a flight from San Diego to Panama?

Currently, September is the cheapest month in which you can book a flight from San Diego to Panama (average of $200). Flying from San Diego to Panama in April is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to PA?

Find hourly flight availability from San Diego to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

When flying from San Diego to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from San Diego to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to Panama?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to Panama from San Diego.

  • How popular is this San Diego to Panama flight route?

  • How long is the flight from San Diego to Panama?

    A quick flight from San Diego to Panama can take about 6h 02m. Copa Airlines provides one of the quickest options available for as low as $510. There are 2910 mi between San Diego and Panama. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from San Diego to Panama?

    Looking for the cheapest flight from San Diego to Panama? While on average our users pay $466, our data indicates the cheapest price to be $229. The most popular route (San Diego - Panama City Tocumen Intl), is priced around $510.

  • Can I find deals for flights from San Diego to Panama that include hotel bookings?

    Yes. In addition to deals on San Diego to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Panama.

  • Can I find deals for business class flights from San Diego to Panama?

    Yes. Cheapflights offers flight deals from San Diego to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Panama?

    Currently, September is the cheapest month in which you can book a flight from San Diego to Panama (average of $200). Flying from San Diego to Panama in April is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from San Diego to Panama

Discover the top 4 airlines that operate flights from San Diego to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$234Average$522FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$279Average$597FlexibilityNo cancel feeOn-time69%
DeltaCheapest$355Average$562FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$489Average$746FlexibilityNo cancel feeOn-time71%

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