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$175+ Cheap flights from San Diego (SAN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
nov. 27 — dic. 41
jue. 11/27
jue. 12/4
1 adult, Economy
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Cheap flight deals from San Diego to Panama

Keep the following information in mind while searching for San Diego to Panama flight deals. Data was last updated octubre 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$409
(Copa Airlines)

One-way from

$175
(Copa Airlines)

Popular in

January

Cheapest in

September

Average price

$489

Good round-trip deal

$438 or less

Good one-way deal

$189 or less
Provider with most accurate pricing for San Diego-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for San Diego-Panama City Tocumen Intl flights.
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From San Diego to Panama
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One-way flight from San Diego to Panama
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Highest demand for flights based on searches. 16% potential increase in price ($107 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from San Diego to Panama.
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Price to beat on a one-way flight from San Diego to Panama.
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Find flight deals from San Diego to Panama

Cheapest flights from San Diego to Panama
Explore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/78:12 pmSAN - PTY
Nonstop6h 08mCopa Airlines
mar. 12/161:45 pmPTY - SAN
Nonstop6h 52mCopa Airlines
Deal found 10/28$409
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1010:30 pmSAN - PTY
1 stop12h 42mDelta
jue. 11/133:37 pmPTY - SAN
1 stop11h 06mDelta
Deal found 10/27$414
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/610:35 pmSAN - PTY
1 stop14h 07mAmerican Airlines
mar. 12/92:50 pmPTY - SAN
1 stop11h 10mAmerican Airlines
Deal found 10/27$423
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/28:00 pmSAN - PTY
2 stops20h 38mUnited Airlines
mié. 12/108:55 amPTY - SAN
1 stop12h 26mUnited Airlines
Deal found 10/27$424
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/710:35 pmSAN - PTY
1 stop12h 12mAmerican Airlines
mar. 12/164:43 pmPTY - SAN
2 stops18h 45mAmerican Airlines
Deal found 10/26$428
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1010:30 pmSAN - PTY
1 stop12h 42mDelta
mié. 11/123:37 pmPTY - SAN
1 stop31h 36mDelta
Deal found 10/27$434
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/77:50 pmSAN - PTY
1 stop19h 59mUnited Airlines
sáb. 11/228:55 amPTY - SAN
1 stop15h 58mUnited Airlines
Deal found 10/28$439
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/85:55 pmSAN - PTY
2 stops22h 43mUnited Airlines
sáb. 11/228:55 amPTY - SAN
1 stop14h 10mUnited Airlines
Deal found 10/28$443
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/71:10 pmSAN - PTY
1 stop26h 39mUnited Airlines
dom. 11/163:35 pmPTY - SAN
1 stop11h 38mUnited Airlines
Deal found 10/28$445
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/218:10 pmSAN - PTY
Nonstop6h 10mCopa Airlines
lun. 12/11:45 pmPTY - SAN
Nonstop6h 52mCopa Airlines
Deal found 10/27$456
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/38:00 pmSAN - DAV
2 stops34h 09mUnited Airlines
mié. 12/109:50 amDAV - SAN
2 stops37h 06mUnited Airlines
Deal found 10/27$839
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2911:02 amSAN - DAV
2 stops20h 01mUnited Airlines
mié. 11/59:53 amDAV - SAN
2 stops17h 20mUnited Airlines
Deal found 10/28$1,189

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

San Diego

Fly to

Panama

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mié. 1/21

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

lun. 1/26

1:45 pm-5:41 pm

Nonstop6h 56m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

lun. 12/8

8:12 pm-5:20 am

Nonstop6h 08m

Panama City Tocumen Intl

lun. 12/22

1:45 pm-5:37 pm

Nonstop6h 52m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mié. 11/26

8:10 pm-5:20 am

Nonstop6h 10m

Panama City Tocumen Intl

mié. 12/3

1:45 pm-5:37 pm

Nonstop6h 52m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mié. 1/7

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

mié. 1/21

1:45 pm-5:41 pm

Nonstop6h 56m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

vie. 11/28

6:24 am-7:59 pm

1 stop10h 35m

Panama City Tocumen Intl

dom. 12/7

8:05 am-11:35 pm

1 stop18h 30m

$424

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

lun. 12/8

10:30 pm-2:21 pm

1 stop12h 51m

Panama City Tocumen Intl

lun. 12/22

3:22 pm-11:28 pm

1 stop11h 06m

$424

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

lun. 11/10

5:55 pm-2:45 pm

3 stops17h 50m

Panama City Tocumen Intl

jue. 11/13

8:55 am-11:44 pm

2 stops17h 49m

$428

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mié. 12/3

8:00 pm-7:38 pm

2 stops20h 38m

Panama City Tocumen Intl

jue. 12/11

8:55 am-11:42 pm

2 stops17h 47m

$428

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mar. 12/2

4:08 pm-2:45 pm

2 stops19h 37m

Panama City Tocumen Intl

mié. 12/10

8:55 am-7:52 pm

2 stops13h 57m

$428

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

mié. 1/7

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

mié. 1/21

4:41 pm-4:36 pm

1 stop26h 55m

$433

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 20 results
1
2

Best time to book a flight from San Diego to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Panama

What is the cheapest month to book a flight from San Diego to Panama?

Currently, September is the cheapest month in which you can book a flight from San Diego to Panama (average of $200). Flying from San Diego to Panama in December is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to PA?

Find hourly flight availability from San Diego to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 28, 2025.

One of the essential ways to save on airfare from San Diego to Panama is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 29% on airfare.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated octubre 28, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from San Diego to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
7,995 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,560 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,996 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Panama?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to Panama from San Diego.

  • How popular is this San Diego to Panama flight route?

    The San Diego to Panama flight path was viewed by 13 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from San Diego to Panama?

    A quick flight from San Diego to Panama can take about 6h 04m. Copa Airlines provides one of the quickest options available for as low as $409. There are 2910 mi between San Diego and Panama. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Diego to Panama one-way?

    $175 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $210 and $245, respectively.

  • What are the cheapest flights from San Diego to Panama?

    Looking for the cheapest flight from San Diego to Panama? While on average our users pay $886, our data indicates the cheapest price to be $136. The most popular route (San Diego - Panama City Tocumen Intl), is priced around $409.

  • Can I find deals for flights from San Diego to Panama that include hotel bookings?

    Yes. In addition to deals on San Diego to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Panama.

  • Can I find deals for business class flights from San Diego to Panama?

    Yes. Cheapflights offers flight deals from San Diego to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Panama?

    Currently, September is the cheapest month in which you can book a flight from San Diego to Panama (average of $200). Flying from San Diego to Panama in December is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from San Diego to Panama

Discover the top 4 airlines that operate flights from San Diego to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$270Average$501FlexibilityNo cancel feeOn-time70%
DeltaCheapest$355Average$562FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$403Average$616FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$528Average$701FlexibilityNo cancel feeOn-time71%

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