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Panama

$206+ Cheap flights from San Diego (SAN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from San Diego to Panama

Keep the following information in mind while searching for San Diego to Panama flight deals. Data was last updated September 11, 2025.

Round-trip from

$604
(Trip.com)

One-way from

$206
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$396

Good round-trip deal

$413 or less

Good one-way deal

$194 or less
From San Diego to Panama
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One-way flight from San Diego to Panama
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Highest demand for flights based on searches. 14% potential increase in price ($100 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from San Diego to Panama.
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Price to beat on a one-way flight from San Diego to Panama.
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Find flight deals from San Diego to Panama

Cheapest flights from San Diego to Panama
Explore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Trip.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:20 pmSAN - PTY
2 stops13h 05mMultiple Airlines
Sun 10/128:10 pmPTY - SAN
2 stops22h 22mMultiple Airlines
Deal found 9/11$604
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:10 pmSAN - PTY
Nonstop6h 10mCopa Airlines
Sun 11/161:15 pmPTY - SAN
Nonstop6h 48mCopa Airlines
Deal found 9/11$609
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:50 pmSAN - PTY
2 stops20h 48mUnited Airlines
Thu 11/138:55 amPTY - SAN
1 stop10h 30mUnited Airlines
Deal found 9/11$623
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:47 pmSAN - PTY
2 stops16h 58mUnited Airlines
Wed 11/128:55 amPTY - SAN
1 stop12h 29mUnited Airlines
Deal found 9/11$628
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:30 pmSAN - PTY
1 stop12h 42mDelta
Mon 11/103:37 pmPTY - SAN
1 stop21h 20mDelta
Deal found 9/11$638
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:50 pmSAN - PTY
1 stop19h 59mUnited Airlines
Sun 11/23:35 pmPTY - SAN
1 stop19h 31mUnited Airlines
Deal found 9/11$658
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:10 pmSAN - PTY
Nonstop6h 10mMultiple Airlines
Mon 11/104:12 pmPTY - SAN
3 stops34h 38mMultiple Airlines
Deal found 9/11$659
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:10 pmSAN - PTY
Nonstop6h 10mMultiple Airlines
Fri 11/145:55 pmPTY - SAN
3 stops22h 33mMultiple Airlines
Deal found 9/11$660
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:10 pmSAN - PTY
Nonstop6h 10mMultiple Airlines
Sat 11/155:55 pmPTY - SAN
3 stops24h 19mMultiple Airlines
Deal found 9/11$662
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:40 pmSAN - PTY
2 stops15h 05mUnited Airlines
Fri 11/78:55 amPTY - SAN
2 stops18h 18mUnited Airlines
Deal found 9/11$663
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:10 pmSAN - PTY
Nonstop6h 10mMultiple Airlines
Thu 11/135:55 pmPTY - SAN
3 stops27h 37mMultiple Airlines
Deal found 9/11$671
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/58:10 pmSAN - PTY
Nonstop6h 10mCopa Airlines
Wed 11/121:15 pmPTY - SAN
Nonstop6h 48mCopa Airlines
Deal found 9/11$675

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

San Diego

Fly to

Panama

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 11/12

7:50 pm-7:38 pm

2 stops20h 48m

Panama City Tocumen Intl

Wed 11/19

8:55 am-8:05 pm

1 stop14h 10m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 11/7

7:50 pm-6:49 pm

1 stop19h 59m

Panama City Tocumen Intl

Wed 11/12

8:55 am-6:24 pm

1 stop12h 29m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 11/7

7:50 pm-6:49 pm

1 stop19h 59m

Panama City Tocumen Intl

Sun 11/16

3:35 pm-12:13 am

1 stop11h 38m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 11/8

7:50 pm-2:45 pm

2 stops15h 55m

Panama City Tocumen Intl

Fri 11/14

8:55 am-4:25 pm

1 stop10h 30m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 2/23

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Mon 3/2

4:00 pm-12:12 am

1 stop11h 12m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 11/8

7:50 pm-2:45 pm

2 stops15h 55m

Panama City Tocumen Intl

Wed 11/12

3:35 pm-12:13 am

1 stop11h 38m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 11/11

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Sun 11/16

3:35 pm-12:13 am

1 stop11h 38m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 12/10

5:23 pm-2:45 pm

1 stop18h 22m

Panama City Tocumen Intl

Wed 12/17

11:35 am-9:51 pm

1 stop13h 16m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 11/4

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Fri 11/14

8:55 am-8:05 pm

1 stop14h 10m

$623

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 1/7

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Thu 1/22

8:55 am-4:36 pm

1 stop10h 41m

$623

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 21 results
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Best time to book a flight from San Diego to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Panama

What is the cheapest month to book a flight from San Diego to Panama?

Currently, October is the cheapest month in which you can book a flight from San Diego to Panama (average of $478). Flying from San Diego to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to PA?

Find hourly flight availability from San Diego to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from San Diego to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from San Diego to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Panama?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to Panama from San Diego.

  • How popular is this San Diego to Panama flight route?

    The San Diego to Panama flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from San Diego to Panama?

    A quick flight from San Diego to Panama can take about 17h 13m. United Airlines provides one of the quickest options available for as low as $1,009. There are 2783 mi between San Diego and Panama. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from San Diego to Panama?

    Looking for the cheapest flight from San Diego to Panama? While on average our users pay $372, our data indicates the cheapest price to be $170. The most popular route (San Diego - Panama City Tocumen Intl), is priced around $609.

  • Can I find deals for flights from San Diego to Panama that include hotel bookings?

    Yes. In addition to deals on San Diego to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Panama.

  • Can I find deals for business class flights from San Diego to Panama?

    Yes. Cheapflights offers flight deals from San Diego to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Panama?

    Currently, October is the cheapest month in which you can book a flight from San Diego to Panama (average of $478). Flying from San Diego to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to Panama

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Top 4 airlines flying from San Diego to Panama

Discover the top 4 airlines that operate flights from San Diego to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$224Average$473FlexibilityNo cancel feeOn-time70%
DeltaCheapest$355Average$564FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$403Average$623FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$586Average$701FlexibilityNo cancel feeOn-time71%

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