Panama

$169+ Cheap flights from North Carolina to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
Jun 21 — Jun 281
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Cheap flight deals from North Carolina to Panama

Keep the following information in mind while searching for North Carolina to Panama flight deals. Data was last updated June 16, 2025.

Round-trip from

$351
(Delta)

One-way from

$169
(Delta)

Popular in

December

Cheapest in

September

Average price

$569

Good round-trip deal

$362 or less

Good one-way deal

$161 or less
From North Carolina to Panama
One-way flight from North Carolina to Panama
Highest demand for flights based on searches. 16% potential increase in price ($112 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($29 potential savings vs. average RT price).
Average for round-trip flights in June 2025
Price to beat on a round-trip flight from North Carolina to Panama.
Price to beat on a one-way flight from North Carolina to Panama.

Find flight deals from North Carolina to Panama

Cheapest flights from North Carolina to Panama
Explore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.

This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/135:30 amORF - PTY
1 stop8h 20mDelta
Wed 8/272:05 pmPTY - ORF
1 stop9h 19mDelta
Deal found 6/15$351
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/137:28 pmORF - PTY
2 stops20h 02mAmerican Airlines
Wed 8/273:30 pmPTY - ORF
2 stops20h 45mAmerican Airlines
Deal found 6/13$356
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:00 amORF - PTY
1 stop8h 50mUnited Airlines
Tue 9/23:30 pmPTY - ORF
1 stop30h 00mUnited Airlines
Deal found 6/14$368
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:25 amGSO - PTY
1 stop8h 24mDelta
Thu 10/22:14 pmPTY - GSO
1 stop8h 40mDelta
Deal found 6/15$393
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/45:40 amAVL - PTY
1 stop8h 33mDelta
Thu 8/72:28 pmPTY - AVL
1 stop8h 16mDelta
Deal found 6/14$393
This Copa Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/74:21 pmRDU - PTY
Nonstop4h 25mCopa Airlines
Fri 9/128:57 amPTY - RDU
Nonstop4h 31mCopa Airlines
Deal found 6/14$403
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/76:30 amRDU - PTY
1 stop7h 20mDelta
Fri 9/122:14 pmPTY - RDU
1 stop8h 41mDelta
Deal found 6/16$417
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:00 amRDU - PTY
2 stops9h 30mAmerican Airlines
Wed 8/273:30 pmPTY - RDU
2 stops19h 50mAmerican Airlines
Deal found 6/15$422
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/39:15 amAVL - PTY
1 stop12h 04mMultiple Airlines
Fri 8/812:03 pmPTY - AVL
1 stop9h 01mMultiple Airlines
Deal found 6/14$439
This Mytrip deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/306:00 amCLT - PTY
1 stop15h 19mMultiple Airlines
Wed 8/612:03 pmPTY - CLT
1 stop9h 13mMultiple Airlines
Deal found 6/15$458
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2810:25 pmCLT - PTY
1 stop17h 05mAmerican Airlines
Tue 9/23:30 pmPTY - CLT
1 stop16h 43mAmerican Airlines
Deal found 6/14$467
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/75:36 amCLT - PTY
1 stop8h 37mDelta
Wed 8/132:05 pmPTY - CLT
1 stop8h 46mDelta
Deal found 6/16$468

Cheapflights Fare Finder

Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
Use the filters below to find and compare flights from North Carolina to Panama that are best for you.

Fly from

North Carolina

Fly to

Panama

Route

Depart

Return

Price

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 8/13

5:30 am-12:50 pm

1 stop8h 20m

Panama City Tocumen Intl

Wed 8/27

2:05 pm-12:24 am

1 stop9h 19m

$351

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 8/13

7:28 pm-2:30 pm

2 stops20h 02m

Panama City Tocumen Intl

Wed 8/27

3:30 pm-1:15 pm

2 stops20h 45m

$356

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 8/27

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Tue 9/2

3:30 pm-10:30 pm

1 stop30h 00m

$368

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Thu 9/11

5:25 am-12:49 pm

1 stop8h 24m

Panama City Tocumen Intl

Thu 10/2

2:14 pm-11:54 pm

1 stop8h 40m

$393

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Mon 8/4

5:40 am-1:13 pm

1 stop8h 33m

Panama City Tocumen Intl

Thu 8/7

2:28 pm-11:44 pm

1 stop8h 16m

$393

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 9/7

4:21 pm-7:46 pm

Nonstop4h 25m

Panama City Tocumen Intl

Fri 9/12

8:57 am-2:28 pm

Nonstop4h 31m

$403

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 9/7

6:30 am-12:50 pm

1 stop7h 20m

Panama City Tocumen Intl

Fri 9/12

2:14 pm-11:55 pm

1 stop8h 41m

$417

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 8/22

6:00 am-2:30 pm

2 stops9h 30m

Panama City Tocumen Intl

Wed 8/27

3:30 pm-12:20 pm

2 stops19h 50m

$422

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Sun 8/3

9:15 am-8:19 pm

1 stop12h 04m

Panama City Tocumen Intl

Fri 8/8

12:03 pm-10:04 pm

1 stop9h 01m

$439

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 7/30

6:00 am-8:19 pm

1 stop15h 19m

Panama City Tocumen Intl

Wed 8/6

12:03 pm-10:16 pm

1 stop9h 13m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Showing 1-10 of 46 results
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Best time to book a flight from North Carolina to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama

What is the cheapest month to book a flight from North Carolina to Panama?

Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PA?

Find hourly flight availability from North Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated June 16, 2025.
Read through reviews of airlines operating flights from North Carolina to Panama, such as Delta, Copa Airlines and Aeromexico. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this North Carolina to Panama flight route?

  • What are the cheapest airlines to fly from North Carolina to Panama one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $169. Users have also found prices from $175 and $194 on United Airlines and American Airlines, respectively.

  • Can I find deals for flights from North Carolina to Panama that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama.

  • Can I find deals for business class flights from North Carolina to Panama?

    Yes. Cheapflights offers flight deals from North Carolina to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from North Carolina to Panama

Discover the top 4 airlines that operate flights from North Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$588FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$282Average$415FlexibilityNo cancel feeOn-time70%
DeltaCheapest$302Average$564FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$498FlexibilityNo cancel feeOn-time69%

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