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$164+ Cheap flights from North Carolina to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
ago. 5 — ago. 121
mar. 8/5
mar. 8/12
1 adult, Economy
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Cheap flight deals from North Carolina to Panama

Keep the following information in mind while searching for North Carolina to Panama flight deals. Data was last updated julio 31, 2025.

Round-trip from

$353
(Copa Airlines)

One-way from

$164
(Delta)

Popular in

December

Cheapest in

September

Average price

$613

Good round-trip deal

$359 or less

Good one-way deal

$200 or less
From North Carolina to Panama
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One-way flight from North Carolina to Panama
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Highest demand for flights based on searches. 12% potential increase in price ($79 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from North Carolina to Panama.
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Price to beat on a one-way flight from North Carolina to Panama.
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Find flight deals from North Carolina to Panama

Cheapest flights from North Carolina to Panama
Explore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 31, 2025.

This Copa Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/254:22 pmRDU - PTY
Nonstop4h 24mCopa Airlines
dom. 9/78:57 amPTY - RDU
Nonstop4h 30mCopa Airlines
Deal found 7/30$353
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/145:15 amRDU - PTY
1 stop8h 41mDelta
mié. 10/222:21 pmPTY - RDU
1 stop8h 41mDelta
Deal found 7/30$367
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/196:00 amRDU - PTY
1 stop9h 31mAmerican Airlines
dom. 9/283:31 pmPTY - RDU
1 stop7h 14mAmerican Airlines
Deal found 7/30$372
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/36:15 amORF - PTY
1 stop7h 40mAmerican Airlines
vie. 9/123:31 pmPTY - ORF
1 stop7h 28mAmerican Airlines
Deal found 7/29$403
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/276:15 amORF - PTY
2 stops13h 22mUnited Airlines
lun. 9/83:30 pmPTY - ORF
2 stops18h 32mUnited Airlines
Deal found 7/29$408
This Avianca Connect deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/210:17 amCLT - PTY
2 stops14h 53mMultiple Airlines
mié. 10/83:20 amPTY - CLT
2 stops16h 41mMultiple Airlines
Deal found 7/31$415
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/65:30 amORF - PTY
1 stop8h 20mDelta
mar. 9/92:05 pmPTY - ORF
1 stop9h 19mDelta
Deal found 7/28$423
This Avianca Connect deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/225:45 amORF - PTY
2 stops16h 25mMultiple Airlines
mar. 9/233:20 amPTY - ORF
2 stops18h 28mMultiple Airlines
Deal found 7/29$431
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/136:00 amGSO - PTY
1 stop7h 55mUnited Airlines
mar. 11/1810:00 amPTY - GSO
1 stop11h 03mUnited Airlines
Deal found 7/31$465
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/255:18 amCLT - PTY
1 stop10h 13mAmerican Airlines
mar. 9/301:45 pmPTY - CLT
1 stop16h 40mAmerican Airlines
Deal found 7/30$467
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/138:11 pmGSO - PTY
2 stops17h 25mAmerican Airlines
mar. 11/182:43 pmPTY - GSO
2 stops19h 06mAmerican Airlines
Deal found 7/31$472
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/258:03 pmFAY - PTY
2 stops19h 28mAmerican Airlines
mar. 9/301:45 pmPTY - FAY
2 stops19h 00mAmerican Airlines
Deal found 7/30$472

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from North Carolina to Panama that are best for you.

Fly from

North Carolina

Fly to

Panama

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

lun. 8/25

4:22 pm-7:46 pm

Nonstop4h 24m

Panama City Tocumen Intl

dom. 9/7

8:57 am-2:27 pm

Nonstop4h 30m

$353

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

mar. 10/14

5:15 am-12:56 pm

1 stop8h 41m

Panama City Tocumen Intl

mié. 10/22

2:21 pm-12:02 am

1 stop8h 41m

$367

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

vie. 9/19

6:00 am-2:31 pm

1 stop9h 31m

Panama City Tocumen Intl

dom. 9/28

3:31 pm-11:45 pm

1 stop7h 14m

$372

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

mié. 9/3

6:15 am-12:55 pm

1 stop7h 40m

Panama City Tocumen Intl

vie. 9/12

3:31 pm-11:59 pm

1 stop7h 28m

$403

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

mié. 8/27

6:15 am-6:37 pm

2 stops13h 22m

Panama City Tocumen Intl

lun. 9/8

3:30 pm-11:02 am

2 stops18h 32m

$408

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 10/2

10:17 am-12:10 am

2 stops14h 53m

Panama City Tocumen Intl

mié. 10/8

3:20 am-9:01 pm

2 stops16h 41m

$415

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

sáb. 9/6

5:30 am-12:50 pm

1 stop8h 20m

Panama City Tocumen Intl

mar. 9/9

2:05 pm-12:24 am

1 stop9h 19m

$423

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

lun. 9/22

5:45 am-9:10 pm

2 stops16h 25m

Panama City Tocumen Intl

mar. 9/23

3:20 am-10:48 pm

2 stops18h 28m

$431

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

jue. 11/13

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

mar. 11/18

10:00 am-9:03 pm

1 stop11h 03m

$465

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 9/25

5:18 am-2:31 pm

1 stop10h 13m

Panama City Tocumen Intl

mar. 9/30

1:45 pm-7:25 am

1 stop16h 40m

$467

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 53 results
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Best time to book a flight from North Carolina to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama

What is the cheapest month to book a flight from North Carolina to Panama?

Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PA?

Find hourly flight availability from North Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated julio 31, 2025.
Read through reviews of airlines operating flights from North Carolina to Panama, such as Delta, Copa Airlines, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
WestJet
7.2
Good
2,978 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this North Carolina to Panama flight route?

    Flights from North Carolina to Panama have been viewed 36 times in the past calendar month.

  • What are the cheapest airlines to fly from North Carolina to Panama one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $164. Users have also found prices from $169 and $189 on United Airlines and American Airlines, respectively.

  • Can I find deals for flights from North Carolina to Panama that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama.

  • Can I find deals for business class flights from North Carolina to Panama?

    Yes. Cheapflights offers flight deals from North Carolina to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Atlanta to San José flights
LaGuardia to Panama City flights
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John F Kennedy Intl to Liberia flights
Baltimore to San Salvador flights
Newark to Liberia flights
George Bush Intcntl to San José flights
Denver to San José flights
Dulles Intl to Panama City flights
Boston to Panama City flights
Atlanta to Panama City flights
Dulles Intl to Guatemala City flights
Miami to San Salvador flights
O'Hare Intl to Liberia flights
Baltimore to San José flights
Fort Lauderdale to San José flights
O'Hare Intl to Panama City flights
Los Angeles to Liberia flights
Reagan-National to San Salvador flights
Dallas/Fort Worth to Guatemala City flights
LaGuardia to Guatemala City flights
Reagan-National to San José flights
Dallas/Fort Worth to San José flights
San Francisco to Guatemala City flights
Fort Lauderdale to Panama City flights

Top 4 airlines flying from North Carolina to Panama

Discover the top 4 airlines that operate flights from North Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$587FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$282Average$413FlexibilityNo cancel feeOn-time70%
DeltaCheapest$297Average$579FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$508FlexibilityNo cancel feeOn-time69%

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