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$169+ Cheap flights from North Carolina to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from North Carolina to Panama

Cheapest flights from North Carolina to Panama
Explore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:42 pmCLT - PTY
1 stop9h 24mMultiple Airlines
Thu 11/209:33 pmPTY - CLT
1 stop11h 16mMultiple Airlines
Deal found 11/2$389
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:42 pmCLT - PTY
1 stop9h 24mMultiple Airlines
Fri 11/1410:47 amPTY - CLT
1 stop11h 10mMultiple Airlines
Deal found 11/1$398
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:45 pmCLT - PTY
1 stop14h 58mAmerican Airlines
Wed 12/242:53 pmPTY - CLT
1 stop9h 06mAmerican Airlines
Deal found 11/2$400
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:36 pmCLT - PTY
2 stops15h 11mAmerican Airlines
Tue 12/92:50 pmPTY - CLT
2 stops15h 39mAmerican Airlines
Deal found 11/2$404
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:29 pmORF - PTY
2 stops18h 20mAmerican Airlines
Thu 11/202:43 pmPTY - ORF
1 stop9h 32mAmerican Airlines
Deal found 11/2$408
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:42 pmCLT - PTY
1 stop9h 24mMultiple Airlines
Wed 11/129:33 pmPTY - CLT
1 stop10h 14mMultiple Airlines
Deal found 11/1$409
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 amORF - PTY
1 stop13h 38mUnited Airlines
Thu 1/810:00 amPTY - ORF
2 stops28h 25mUnited Airlines
Deal found 11/3$416
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:42 pmCLT - PTY
1 stop9h 24mMultiple Airlines
Sat 11/159:33 pmPTY - CLT
1 stop10h 14mMultiple Airlines
Deal found 11/1$416
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1010:42 pmCLT - PTY
1 stop9h 48mMultiple Airlines
Tue 11/188:10 amPTY - CLT
2 stops11h 48mMultiple Airlines
Deal found 11/2$422
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:42 pmCLT - PTY
1 stop9h 24mMultiple Airlines
Thu 11/136:11 pmPTY - CLT
1 stop13h 36mMultiple Airlines
Deal found 11/1$425
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/88:05 pmORF - PTY
2 stops18h 40mUnited Airlines
Tue 11/114:41 pmPTY - ORF
2 stops21h 17mUnited Airlines
Deal found 11/2$428
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/39:38 pmCLT - PTY
1 stop10h 28mMultiple Airlines
Wed 11/59:33 pmPTY - CLT
1 stop10h 14mMultiple Airlines
Deal found 10/31$430

Cheap flight deals from North Carolina to Panama

Keep the following information in mind while searching for North Carolina to Panama flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$389
(Kiwi.com)

One-way from

$169
(United Airlines)

Popular in

December

Cheapest in

November

Average price

$317

Good round-trip deal

$356 or less

Good one-way deal

$200 or less
Provider with most accurate pricing for Raleigh-Durham-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City Tocumen Intl flights.
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From North Carolina to Panama
Search Deals
One-way flight from North Carolina to Panama
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from North Carolina to Panama.
Search Deals
Price to beat on a one-way flight from North Carolina to Panama.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from North Carolina to Panama that are best for you.

Fly from

North Carolina

Fly to

Panama

Route

Depart

Return

Price

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 1/29

6:20 am-1:55 pm

1 stop7h 35m

Panama City Tocumen Intl

Tue 2/3

3:20 pm-12:16 am

1 stop8h 56m

$404

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 1/29

6:10 am-1:27 pm

1 stop7h 17m

Panama City Tocumen Intl

Tue 2/3

2:27 pm-10:59 pm

1 stop8h 32m

$404

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Mon 11/24

8:05 pm-7:38 pm

2 stops23h 33m

Panama City Tocumen Intl

Wed 12/3

4:41 pm-2:03 pm

2 stops21h 22m

$408

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 1/29

6:30 am-1:27 pm

1 stop6h 57m

Panama City Tocumen Intl

Mon 2/2

4:50 pm-7:31 am

2 stops14h 41m

$410

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 2/17

9:54 am-2:02 pm

1 stop28h 08m

Panama City Tocumen Intl

Thu 2/26

3:27 pm-8:42 am

1 stop17h 15m

$412

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 11/13

9:38 pm-4:55 pm

2 stops19h 17m

Panama City Tocumen Intl

Thu 11/20

5:50 pm-8:49 am

2 stops14h 59m

$413

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 12/18

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Thu 1/8

10:00 am-2:25 pm

2 stops28h 25m

$416

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 3/11

7:37 pm-12:10 pm

1 stop17h 33m

Panama City Tocumen Intl

Sat 3/21

1:50 pm-11:09 am

2 stops20h 19m

$426

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Sun 11/23

8:05 pm-7:38 pm

2 stops23h 33m

Panama City Tocumen Intl

Fri 12/5

11:35 am-10:30 pm

1 stop10h 55m

$428

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 1/8

5:44 pm-3:38 pm

2 stops21h 54m

Panama City Tocumen Intl

Thu 3/12

1:50 pm-9:52 am

2 stops19h 02m

$440

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 58 results
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Best time to book a flight from North Carolina to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama

What is the cheapest month to book a flight from North Carolina to Panama?

Currently, August is the cheapest month in which you can book a flight from North Carolina to Panama (average of $234). Flying from North Carolina to Panama in June is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PA?

Find hourly flight availability from North Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

It’s optimal to fly from North Carolina to Panama at noon. By choosing this option you can save up to 42% on the cost of your flight, compared to a flight in the evening.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this North Carolina to Panama flight route?

    Flights from North Carolina to Panama have been viewed 21 times in the past calendar month.

  • How long is the flight from North Carolina to Panama?

    There are many flights that can get you from North Carolina to Panama in 7h 17m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance from North Carolina to Panama is about 1931 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from North Carolina to Panama that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama.

  • Can I find deals for business class flights from North Carolina to Panama?

    Yes. Cheapflights offers flight deals from North Carolina to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama?

    Currently, August is the cheapest month in which you can book a flight from North Carolina to Panama (average of $234). Flying from North Carolina to Panama in June is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from North Carolina to Panama

Discover the top 4 airlines that operate flights from North Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$586FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$318Average$460FlexibilityNo cancel feeOn-time70%
DeltaCheapest$367Average$544FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$517FlexibilityNo cancel feeOn-time69%

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