
Keep the following information in mind while searching for Honduras to Panama flight deals. Data was last updated November 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $338 (Avianca) |
One-way from | $308 (Avianca) |
Popular in | October |
Cheapest in | February |
Average price | $439 |
Good round-trip deal | $456 or less |
Good one-way deal | $258 or less |
Fly from
Fly to
Route
Depart
Return
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Fri 12/25
7:40 pm-2:10 am
1 stop5h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San Pedro SulaPanama City
SAP San Pedro Sula Ramon Villeda - PTY Panama City Tocumen Intl
SAPPTY
San Pedro Sula Ramon Villeda
Sat 12/19
9:30 am-2:10 am
1 stop15h 40m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Thu 1/7
10:00 am-2:10 am
1 stop15h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Wed 1/13
5:02 am-8:09 am
Nonstop2h 07m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Mon 11/23
1:56 pm-5:05 pm
Nonstop2h 09m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Tue 2/2
1:56 pm-5:05 pm
Nonstop2h 09m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Wed 2/3
5:01 am-8:09 am
Nonstop2h 08m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Thu 1/14
5:02 am-8:09 am
Nonstop2h 07m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Wed 12/23
4:42 am-7:54 am
Nonstop2h 12m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
ComayaguaPanama City
XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl
XPLPTY
Comayagua Palmerola Intl
Mon 1/4
5:02 am-8:09 am
Nonstop2h 07m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
Everything you need to know about your flight from Honduras to Panama
Overall
Comfort
Entertainment
Crew
Food
Boarding
Reviews
Marcos,Nov 2026
BOS - PTY
Overall
Comfort
Entertainment
Crew
Food
Boarding
Reviews
Marcos,Nov 2026
BOS - PTY
Overall
Comfort
Entertainment
Crew
Food
Boarding
Reviews
Marcos,Nov 2026
BOS - PTY
Find useful and relevant information for your journey from Honduras to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$362 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$284 | Average$405 | FlexibilityNo cancel fee | On-time70% |