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$182+ Cheap flights from Midway (MDW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — PTY
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheap flight deals from Midway to Panama

Keep the following information in mind while searching for Midway to Panama flight deals. Data was last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$500
(Kiwi.com)

One-way from

$182
(Kiwi.com)

Popular in

October

Cheapest in

November

Average price

$700
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
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From Chicago Midway to Panama
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One-way flight from Chicago Midway to Panama
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Midway to Panama

Cheapest flights from Midway to Panama
Explore the most affordable flight options available from Midway to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Trip.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:57 pmMDW - PTY
2 stops13h 53mMultiple Airlines
Wed 12/35:50 pmPTY - MDW
2 stops29h 03mMultiple Airlines
Deal found 10/27$522
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:57 pmMDW - PTY
1 stop13h 09mMultiple Airlines
Thu 12/49:45 amPTY - MDW
2 stops13h 08mMultiple Airlines
Deal found 10/26$523
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:57 pmMDW - PTY
1 stop13h 09mMultiple Airlines
Thu 12/49:45 amPTY - MDW
2 stops13h 08mMultiple Airlines
Deal found 10/26$585
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:15 amMDW - PTY
2 stops22h 51mMultiple Airlines
Wed 1/149:33 pmPTY - MDW
1 stop18h 14mMultiple Airlines
Deal found 10/28$595
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:05 amMDW - PTY
1 stop12h 38mMultiple Airlines
Thu 12/49:45 amPTY - MDW
2 stops13h 08mMultiple Airlines
Deal found 10/26$597
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:05 amMDW - PTY
1 stop12h 38mMultiple Airlines
Wed 12/35:50 pmPTY - MDW
2 stops29h 03mMultiple Airlines
Deal found 10/27$601
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:12 amMDW - PTY
1 stop12h 21mMultiple Airlines
Wed 1/142:55 pmPTY - MDW
2 stops24h 52mMultiple Airlines
Deal found 10/28$612
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:59 pmMDW - PTY
1 stop16h 07mMultiple Airlines
Tue 12/912:33 pmPTY - MDW
2 stops21h 13mMultiple Airlines
Deal found 10/27$621
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:00 amMDW - PTY
1 stop7h 12mDelta
Thu 12/43:46 pmPTY - MDW
1 stop9h 01mDelta
Deal found 10/26$632

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama that are best for you.

Fly from

Midway

Fly to

Panama

Route

Depart

Return

Price

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 1/12

3:52 pm-8:06 am

1 stop15h 14m

Panama City Tocumen Intl

Thu 1/15

5:50 pm-2:47 pm

2 stops21h 57m

$500

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 11/26

5:57 pm-8:06 am

1 stop13h 09m

Panama City Tocumen Intl

Thu 12/4

8:25 am-9:53 pm

1 stop14h 28m

$566

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 3/1

9:30 am-2:02 pm

2 stops27h 32m

Panama City Tocumen Intl

Tue 3/3

3:27 pm-6:34 pm

2 stops28h 07m

$582

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 12/24

8:15 am-8:06 am

2 stops22h 51m

Panama City Tocumen Intl

Wed 1/14

9:33 pm-2:47 pm

1 stop18h 14m

$595

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 1/12

3:52 pm-8:06 am

1 stop15h 14m

Panama City Tocumen Intl

Wed 1/14

10:25 am-9:31 pm

2 stops12h 06m

$623

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 11/24

6:48 pm-2:12 pm

2 stops18h 24m

Panama City Tocumen Intl

Wed 12/3

3:46 pm-8:54 am

2 stops18h 08m

$632

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 11/24

12:25 pm-8:50 am

3 stops19h 25m

$191

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 1/12

3:52 pm-10:30 am

2 stops41h 38m

$201

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 12/11

2:16 pm-6:55 pm

3 stops27h 39m

$207

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Fri 11/7

12:14 pm-8:50 am

3 stops19h 36m

$243

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 13 results
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Best time to book a flight from Midway to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Midway to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to Panama?

    Delta can get you from Chicago Midway Airport to Panama in just under 27h 32m. Your travel time can differ by up to . The distance between Chicago Midway Airport and Panama is about 2316 mi.

  • Can I find deals for flights from Midway to Panama that include hotel bookings?

    Yes. In addition to deals on Midway to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Panama.

  • Can I find deals for business class flights from Midway to Panama?

    Yes. Cheapflights offers flight deals from Midway to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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