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$178+ Cheap flights from Midway (MDW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Midway to Panama

Keep the following information in mind while searching for Midway to Panama flight deals. Data was last updated September 11, 2025.

Round-trip from

$465
(Delta)

One-way from

$178
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$479
From Chicago Midway to Panama
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One-way flight from Chicago Midway to Panama
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Highest demand for flights based on searches. 5% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Midway to Panama

Cheapest flights from Midway to Panama
Explore the most affordable flight options available from Midway to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:00 amMDW - PTY
1 stop6h 55mDelta
Mon 10/62:21 pmPTY - MDW
1 stop7h 53mDelta
Deal found 9/11$465
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:00 amMDW - PTY
1 stop6h 55mDelta
Tue 9/302:10 pmPTY - MDW
2 stops18h 30mDelta
Deal found 9/10$470
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:00 amMDW - PTY
1 stop6h 55mDelta
Fri 10/32:10 pmPTY - MDW
1 stop19h 38mDelta
Deal found 9/10$474
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2510:00 amMDW - PTY
2 stops22h 30mMultiple Airlines
Sat 11/112:33 pmPTY - MDW
1 stop8h 49mMultiple Airlines
Deal found 9/10$562
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/134:24 pmMDW - PTY
1 stop15h 47mMultiple Airlines
Fri 10/178:10 pmPTY - MDW
2 stops26h 37mMultiple Airlines
Deal found 9/11$566
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amMDW - PTY
1 stop12h 59mDelta
Wed 12/33:46 pmPTY - MDW
1 stop8h 46mDelta
Deal found 9/9$586
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:20 amMDW - PTY
1 stop13h 13mMultiple Airlines
Thu 10/309:25 amPTY - MDW
1 stop9h 14mMultiple Airlines
Deal found 9/10$590
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:00 amMDW - PTY
1 stop7h 12mDelta
Sat 12/68:05 amPTY - MDW
1 stop8h 38mDelta
Deal found 9/10$602
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:00 amMDW - PTY
1 stop6h 55mDelta
Tue 9/302:10 pmPTY - MDW
2 stops22h 18mDelta
Deal found 9/10$619
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:15 amMDW - PTY
1 stop13h 18mMultiple Airlines
Sat 9/279:25 amPTY - MDW
1 stop13h 52mMultiple Airlines
Deal found 9/10$621
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:00 amMDW - PTY
1 stop6h 55mDelta
Thu 10/22:10 pmPTY - MDW
1 stop19h 30mDelta
Deal found 9/10$623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama that are best for you.

Fly from

Midway

Fly to

Panama

Route

Depart

Return

Price

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 11/3

6:00 am-1:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Thu 11/6

3:21 pm-10:14 pm

1 stop7h 53m

$465

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 9/22

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Thu 10/2

2:10 pm-8:40 am

2 stops18h 30m

$470

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 9/22

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Tue 9/30

2:10 pm-8:40 am

2 stops18h 30m

$470

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 9/22

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 10/1

2:10 pm-9:40 am

1 stop19h 30m

$474

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 9/22

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Fri 10/3

2:10 pm-9:48 am

1 stop19h 38m

$474

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 10/25

10:00 am-8:30 am

2 stops22h 30m

Panama City Tocumen Intl

Sat 11/1

12:33 pm-9:22 pm

1 stop8h 49m

$562

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 3/11

2:20 pm-6:34 pm

2 stops28h 14m

$582

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 11/10

6:00 am-2:12 pm

1 stop7h 12m

Panama City Tocumen Intl

Thu 11/13

3:37 pm-11:32 pm

1 stop8h 55m

$586

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Fri 10/24

12:18 pm-12:45 am

2 stops12h 27m

$178

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 11/5

2:06 pm-10:20 am

3 stops43h 14m

$203

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 15 results
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Best time to book a flight from Midway to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Midway to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to Panama?

    Delta can get you from Chicago Midway Airport to Panama in just under 6h 56m. Your travel time can differ by up to . The distance between Chicago Midway Airport and Panama is about 2316 mi.

  • Can I find deals for flights from Midway to Panama that include hotel bookings?

    Yes. In addition to deals on Midway to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Panama.

  • Can I find deals for business class flights from Midway to Panama?

    Yes. Cheapflights offers flight deals from Midway to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to Panama?

    Currently, October is the cheapest month in which you can book a flight from Chicago Midway Airport to Panama (average of $478). Flying from Chicago Midway Airport to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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