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$183+ Cheap flights from Midway (MDW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — PTY
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Midway to Panama

Cheapest flights from Midway to Panama
Explore the most affordable flight options available from Midway to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:00 am
MDW
-
PTY
1 stop10h 06m
Multiple Airlines
Wed 3/119:33 pm
PTY
-
MDW
1 stop16h 08m
Multiple Airlines
Deal found 2/2$458
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:15 am
MDW
-
PTY
1 stop8h 51m
Multiple Airlines
Sun 3/89:33 pm
PTY
-
MDW
1 stop16h 08m
Multiple Airlines
Deal found 2/1$490
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:25 am
MDW
-
PTY
1 stop13h 09m
Multiple Airlines
Thu 3/510:26 am
PTY
-
MDW
1 stop13h 03m
Multiple Airlines
Deal found 2/2$506
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:30 am
MDW
-
PTY
1 stop12h 04m
Multiple Airlines
Tue 3/1010:26 am
PTY
-
MDW
1 stop10h 28m
Multiple Airlines
Deal found 2/2$516
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 am
MDW
-
PTY
1 stop9h 06m
Multiple Airlines
Wed 3/119:33 pm
PTY
-
MDW
1 stop16h 08m
Multiple Airlines
Deal found 2/2$528
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:30 am
MDW
-
PTY
1 stop12h 04m
Multiple Airlines
Sat 3/710:26 am
PTY
-
MDW
1 stop12h 58m
Multiple Airlines
Deal found 2/2$529
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:30 am
MDW
-
PTY
1 stop12h 04m
Multiple Airlines
Sun 3/810:26 am
PTY
-
MDW
1 stop9h 21m
Multiple Airlines
Deal found 2/1$530
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:00 am
MDW
-
PTY
1 stop13h 34m
Multiple Airlines
Wed 2/255:50 pm
PTY
-
MDW
2 stops21h 06m
Multiple Airlines
Deal found 1/31$550
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:30 am
MDW
-
PTY
1 stop12h 04m
Multiple Airlines
Thu 3/1210:26 am
PTY
-
MDW
1 stop9h 21m
Multiple Airlines
Deal found 2/2$571
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:00 am
MDW
-
PTY
1 stop10h 06m
Multiple Airlines
Wed 3/189:33 pm
PTY
-
MDW
1 stop16h 08m
Multiple Airlines
Deal found 2/2$573

Find flight deals from Midway to Panama

Keep the following information in mind while searching for Midway to Panama flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$458
(Kiwi.com)

One-way from

$183
(Kiwi.com)

Popular in

May

Cheapest in

July

Average price

$572
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
Search Deals
From Chicago Midway to Panama
Search Deals
One-way flight from Chicago Midway to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama that are best for you.

Fly from

Midway

Fly to

Panama

Route

Depart

Return

Price

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 3/8

6:00 am-4:06 pm

1 stop10h 06m

Panama City Tocumen Intl

Thu 3/12

9:33 pm-1:41 pm

1 stop16h 08m

$531

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 4/20

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Thu 4/23

2:27 pm-10:28 pm

1 stop8h 01m

$580

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 4/15

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Mon 4/20

2:27 pm-10:28 pm

1 stop8h 01m

$580

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 2/26

5:16 pm-8:06 am

2 stops13h 50m

Panama City Tocumen Intl

Thu 3/5

10:26 am-10:29 pm

1 stop13h 03m

$616

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 3/4

6:00 am-1:50 pm

1 stop6h 50m

Panama City Tocumen Intl

Wed 3/11

2:28 pm-10:31 pm

1 stop8h 03m

$628

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 3/8

6:00 am-1:03 pm

1 stop7h 03m

Panama City Tocumen Intl

Tue 3/10

2:28 pm-10:31 pm

1 stop8h 03m

$628

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/3

6:40 pm-1:50 pm

1 stop18h 10m

Panama City Tocumen Intl

Wed 3/11

2:28 pm-10:31 pm

1 stop8h 03m

$628

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/3

6:00 am-1:50 pm

1 stop6h 50m

Panama City Tocumen Intl

Mon 3/9

2:28 pm-5:54 pm

2 stops27h 26m

$632

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/3

6:40 pm-1:50 pm

1 stop18h 10m

Panama City Tocumen Intl

Thu 3/12

2:28 pm-8:53 am

2 stops18h 25m

$632

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 3/2

6:40 pm-1:50 pm

1 stop18h 10m

Panama City Tocumen Intl

Thu 3/12

2:28 pm-8:53 am

2 stops18h 25m

$632

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 21 results
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Best time to book a flight from Midway to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Midway to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to Panama?

    Delta can get you from Chicago Midway Airport to Panama in just under 7h 02m. Your travel time can differ by up to . The distance between Chicago Midway Airport and Panama is about 2316 mi.

  • Can I find deals for flights from Midway to Panama that include hotel bookings?

    Yes. In addition to deals on Midway to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Panama.

  • Can I find deals for business class flights from Midway to Panama?

    Yes. Cheapflights offers flight deals from Midway to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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