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$539+ Cheap flights from Midway (MDW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — PTY
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Midway to Panama

Cheapest flights from Midway to Panama
Explore the most affordable flight options available from Midway to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:15 amMDW - PTY
1 stop12h 18mMultiple Airlines
Tue 12/232:55 pmPTY - MDW
2 stops24h 42mMultiple Airlines
Deal found 12/13$858
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:42 pmMDW - PTY
1 stop21h 51mMultiple Airlines
Mon 12/227:50 pmPTY - MDW
2 stops43h 47mMultiple Airlines
Deal found 12/14$871
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:32 pmMDW - PTY
1 stop15h 34mMultiple Airlines
Mon 1/510:28 pmPTY - MDW
2 stops24h 49mMultiple Airlines
Deal found 12/15$1,020
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:12 amMDW - PTY
1 stop12h 21mMultiple Airlines
Thu 1/111:48 amPTY - MDW
2 stops33h 57mMultiple Airlines
Deal found 12/13$1,126
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amMDW - PTY
1 stop12h 33mMultiple Airlines
Sun 1/410:28 pmPTY - MDW
2 stops23h 17mMultiple Airlines
Deal found 12/14$1,129
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:50 amMDW - PTY
1 stop9h 10mDelta
Wed 12/313:22 pmPTY - MDW
1 stop8h 00mDelta
Deal found 12/15$1,202
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amMDW - PTY
1 stop13h 00mDelta
Thu 1/18:00 amPTY - MDW
1 stop7h 44mDelta
Deal found 12/15$1,242
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:15 amMDW - PTY
2 stops25h 35mMultiple Airlines
Sat 12/279:25 amPTY - MDW
1 stop13h 47mMultiple Airlines
Deal found 12/14$1,254
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:32 pmMDW - PTY
1 stop15h 34mMultiple Airlines
Sun 1/410:28 pmPTY - MDW
2 stops23h 17mMultiple Airlines
Deal found 12/14$1,270
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amMDW - PTY
1 stop13h 00mDelta
Mon 1/53:20 pmPTY - MDW
1 stop7h 47mDelta
Deal found 12/15$1,271
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amMDW - PTY
1 stop13h 00mDelta
Thu 1/18:00 amPTY - MDW
1 stop7h 44mDelta
Deal found 12/13$1,351

Find flight deals from Midway to Panama

Keep the following information in mind while searching for Midway to Panama flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$595
(Delta)

One-way from

$539
(Delta)

Popular in

May

Cheapest in

July

Average price

$603
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
Search Deals
From Chicago Midway to Panama
Search Deals
One-way flight from Chicago Midway to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama that are best for you.

Fly from

Midway

Fly to

Panama

Route

Depart

Return

Price

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 2/25

6:00 am-1:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Sun 3/1

3:20 pm-10:42 pm

1 stop8h 22m

$604

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/24

5:38 pm-12:55 pm

1 stop19h 17m

Panama City Tocumen Intl

Wed 6/3

2:20 pm-8:42 am

2 stops18h 22m

$618

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 3/25

5:38 pm-12:55 pm

1 stop19h 17m

Panama City Tocumen Intl

Wed 6/3

2:20 pm-8:42 am

2 stops18h 22m

$618

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 3/23

5:38 pm-12:55 pm

1 stop19h 17m

Panama City Tocumen Intl

Fri 5/29

2:20 pm-8:42 am

2 stops18h 22m

$618

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 3/23

5:38 pm-12:55 pm

1 stop19h 17m

Panama City Tocumen Intl

Wed 6/3

2:20 pm-8:42 am

2 stops18h 22m

$618

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 2/5

6:20 am-8:34 pm

1 stop13h 14m

Panama City Tocumen Intl

Sun 2/8

10:26 am-10:19 pm

1 stop12h 53m

$622

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 1/29

5:01 pm-8:06 am

2 stops14h 05m

Panama City Tocumen Intl

Sun 2/1

10:26 am-10:19 pm

1 stop12h 53m

$635

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 2/8

6:00 am-1:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Fri 2/13

3:20 pm-10:42 pm

1 stop8h 22m

$657

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 4/20

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Sat 4/25

2:20 pm-8:42 am

2 stops18h 22m

$661

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 3/28

4:30 pm-12:55 pm

1 stop20h 25m

Panama City Tocumen Intl

Fri 5/29

2:20 pm-9:51 am

1 stop19h 31m

$677

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 19 results
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Best time to book a flight from Midway to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Midway to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago Midway Airport to Panama?

    Delta can get you from Chicago Midway Airport to Panama in just under 6h 55m. Your travel time can differ by up to . The distance between Chicago Midway Airport and Panama is about 2316 mi.

  • Can I find deals for flights from Midway to Panama that include hotel bookings?

    Yes. In addition to deals on Midway to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Panama.

  • Can I find deals for business class flights from Midway to Panama?

    Yes. Cheapflights offers flight deals from Midway to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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