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$517+ Cheap flights from Buffalo (BUF) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
ago 5 — ago 121
ter 8/5
ter 8/12
1 adult, Economy
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Cheap flight deals from Buffalo to Panama

Keep the following information in mind while searching for Buffalo to Panama flight deals. Data was last updated julho 31, 2025.

Round-trip from

$517
(Delta)

Popular in

March

Cheapest in

July

Average price

$465
From Buffalo to Panama
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Buffalo to Panama

Cheapest flights from Buffalo to Panama
Explore the most affordable flight options available from Buffalo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julho 31, 2025.

This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 8/226:00 amBUF - PTY
1 stop7h 50mDelta
seg 9/82:05 pmPTY - BUF
1 stop8h 52mDelta
Deal found 7/30$517
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 8/267:05 amBUF - PTY
2 stops13h 26mUnited Airlines
qui 9/43:30 pmPTY - BUF
2 stops24h 22mUnited Airlines
Deal found 7/30$549
This Avianca deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 9/228:00 pmBUF - PTY
3 stops17h 35mAvianca
sáb 9/2710:05 pmPTY - BUF
2 stops22h 08mAvianca
Deal found 7/28$868
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 9/126:59 pmBUF - PTY
1 stop20h 08mMultiple Airlines
qui 9/183:20 amPTY - BUF
2 stops13h 54mMultiple Airlines
Deal found 7/29$1,036
This Copa Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 9/2210:55 amBUF - PTY
1 stop10h 40mCopa Airlines
sáb 9/276:38 pmPTY - BUF
1 stop14h 05mCopa Airlines
Deal found 7/28$1,482

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julho 31, 2025.
Use the filters below to find and compare flights from Buffalo to Panama that are best for you.

Fly from

Buffalo

Fly to

Panama

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

sex 8/22

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

seg 9/8

2:05 pm-11:57 pm

1 stop8h 52m

$517

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

ter 8/26

7:05 am-7:31 pm

2 stops13h 26m

Panama City Tocumen Intl

qui 9/4

3:30 pm-4:52 pm

2 stops24h 22m

$549

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

sáb 8/23

8:00 pm-12:35 pm

3 stops17h 35m

Panama City Tocumen Intl

qua 9/3

10:05 pm-9:16 pm

2 stops22h 11m

$902

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

dom 9/14

7:41 pm-8:15 pm

2 stops25h 34m

Panama City Tocumen Intl

dom 9/21

8:03 am-5:27 pm

1 stop8h 24m

$1,031

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Buffalo to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Panama

What is the cheapest month to book a flight from Buffalo to Panama?

Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama (average of $478). Flying from Buffalo to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to PA?

Find hourly flight availability from Buffalo to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julho 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated julho 31, 2025.
Read through reviews of airlines operating flights from Buffalo to Panama, such as Delta, Copa Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Avianca
6.7
Okay
2,388 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Panama?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Panama.

  • Can I find deals for flights from Buffalo to Panama that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama.

  • Can I find deals for business class flights from Buffalo to Panama?

    Yes. Cheapflights offers flight deals from Buffalo to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Panama?

    Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama (average of $478). Flying from Buffalo to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Buffalo to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to Panama

Discover the top 2 airlines that operate flights from Buffalo to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julho 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$441Average$491FlexibilityNo cancel feeOn-time69%
DeltaCheapest$445Average$666FlexibilityNo cancel feeOn-timeN/A

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