$337+ Cheap flights from Santiago (SCL) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — PTY
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Panama City Tocumen Intl are usually found in March or April, booked 11 days in advance, depart on a Wednesday or Friday and return on a Monday
Cheap flight deals from Santiago to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santiago to Panama CityExplore the most affordable flight options available from Santiago to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Santiago to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Avianca deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:30 am -
1 stop9h 45m
Sat 12/52:30 am -
1 stop10h 40m
Deal found 11/1![Avianca logo]()
$600
This Super.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:15 pm -
1 stop18h 55m
Sat 12/52:30 am -
1 stop10h 40m
Deal found 11/1![Avianca logo]()
$616
This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:15 pm -
1 stop11h 05m
Sat 11/212:30 am -
1 stop10h 40m
Deal found 10/30![Avianca logo]()
$637
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:20 pm -
Nonstop6h 51m
Fri 12/256:21 pm -
Nonstop6h 27m
Deal found 11/3![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:07 am -
Nonstop6h 56m
Tue 12/297:11 pm -
Nonstop6h 32m
Deal found 11/4![Copa Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:07 am -
Nonstop6h 56m
Sun 12/136:21 pm -
Nonstop6h 27m
Deal found 11/3![Copa Airlines logo]()
$664
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:48 am -
Nonstop6h 57m
Mon 1/257:11 pm -
Nonstop6h 35m
Deal found 11/3![Copa Airlines logo]()
$670
This Avianca deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:30 am -
1 stop11h 45m
Tue 12/2210:05 am -
1 stop13h 00m
Deal found 10/31![Avianca logo]()
$672
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:07 am -
Nonstop6h 56m
Sat 12/57:11 pm -
Nonstop6h 32m
Deal found 11/4![Copa Airlines logo]()
$688
This Avianca deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:30 am -
1 stop11h 45m
Fri 1/12:30 am -
1 stop10h 40m
Deal found 11/2![Avianca logo]()
$717
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:07 am -
Nonstop6h 56m
Wed 11/2511:48 am -
Nonstop6h 27m
Deal found 11/2![Copa Airlines logo]()
$720
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/213:48 am -
Nonstop6h 57m
Sat 1/26:21 pm -
Nonstop6h 32m
Deal found 11/3![Copa Airlines logo]()
$730
Best flights from Santiago to Panama CityDiscover carefully curated flight deals from Santiago to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Santiago to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Fri 12/412:20 pm -
Nonstop6h 51m
Fri 12/256:21 pm -
Nonstop6h 27m
Deal found 10/30![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2812:15 pm -
Nonstop6h 56m
Sat 12/53:08 pm -
Nonstop6h 27m
Deal found 10/31![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:20 pm -
Nonstop6h 51m
Tue 12/811:48 am -
Nonstop6h 23m
Deal found 11/3![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:20 pm -
Nonstop6h 51m
Wed 12/1611:48 am -
Nonstop6h 23m
Deal found 11/1![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:20 pm -
Nonstop6h 51m
Thu 12/316:26 pm -
Nonstop6h 27m
Deal found 10/31![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:07 am -
Nonstop6h 56m
Sun 12/67:11 pm -
Nonstop6h 32m
Deal found 11/3![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:07 am -
Nonstop6h 56m
Sun 12/67:11 pm -
Nonstop6h 32m
Deal found 11/1![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:07 am -
Nonstop6h 56m
Mon 12/77:11 pm -
Nonstop6h 32m
Deal found 10/30![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/211:31 am -
Nonstop6h 52m
Sat 1/211:48 am -
Nonstop6h 30m
Deal found 11/1![Copa Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/283:48 am -
Nonstop6h 57m
Sat 1/99:24 pm -
Nonstop6h 33m
Deal found 10/30![Copa Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:20 pm -
Nonstop6h 51m
Mon 12/213:56 pm -
Nonstop6h 27m
Deal found 11/4![Copa Airlines logo]()
$655
Last-minute flights from Santiago to Panama CityDiscover last-minute flight deals from Santiago to Panama City. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Panama City. Data last updated November 4, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:07 am -
Nonstop6h 56m
Wed 11/2511:48 am -
Nonstop6h 27m
Deal found 11/2![Copa Airlines logo]()
$720
This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:15 pm -
1 stop11h 05m
Sat 11/212:30 am -
1 stop10h 40m
Deal found 10/30![Avianca logo]()
$637
This Super.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:15 pm -
1 stop18h 55m
Sat 12/52:30 am -
1 stop10h 40m
Deal found 11/1![Avianca logo]()
$616
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:07 am -
Nonstop6h 56m
Sat 12/57:11 pm -
Nonstop6h 32m
Deal found 11/4![Copa Airlines logo]()
$688
This Avianca deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:30 am -
1 stop9h 45m
Sat 12/52:30 am -
1 stop10h 40m
Deal found 11/1![Avianca logo]()
$600
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:20 pm -
Nonstop6h 51m
Fri 12/256:21 pm -
Nonstop6h 27m
Deal found 11/3![Copa Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:07 am -
Nonstop6h 56m
Sun 12/136:21 pm -
Nonstop6h 27m
Deal found 11/3![Copa Airlines logo]()
$664
This Avianca deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:30 am -
1 stop11h 45m
Tue 12/2210:05 am -
1 stop13h 00m
Deal found 10/31![Avianca logo]()
$672
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:07 am -
Nonstop6h 56m
Tue 12/297:11 pm -
Nonstop6h 32m
Deal found 11/4![Copa Airlines logo]()
$655
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/213:48 am -
Nonstop6h 57m
Sat 1/26:21 pm -
Nonstop6h 32m
Deal found 11/3![Copa Airlines logo]()
$730
This Avianca deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:30 am -
1 stop11h 45m
Fri 1/12:30 am -
1 stop10h 40m
Deal found 11/2![Avianca logo]()
$717
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:48 am -
Nonstop6h 57m
Mon 1/257:11 pm -
Nonstop6h 35m
Deal found 11/3![Copa Airlines logo]()
$670
One-way flights from Santiago to Panama CitySearch for one-way flight options from Santiago to Panama City. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Santiago to Panama City. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Avianca deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:10 am -
1 stop15h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Avianca logo]()
$337
This Jetabroad deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jetabroad is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:10 am -
1 stop17h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Avianca logo]()
$344
This FlightHub deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:30 am -
1 stop9h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Avianca logo]()
$358
This deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:15 pm -
1 stop11h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Avianca logo]()
$371
This Avianca deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/314:15 pm -
1 stop11h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Avianca logo]()
$382
This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:30 am -
1 stop11h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Avianca logo]()
$383
This Avianca deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:30 am -
1 stop9h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Avianca logo]()
$421
This Super.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:30 am -
1 stop11h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Avianca logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:07 am -
2 stops16h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$428
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:45 am -
2 stops27h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$453
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:40 pm -
2 stops13h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$471
Find flight deals from Santiago to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $600 (Avianca) |
One-way from | $337 (Avianca) |
Popular in | September |
Cheapest in | March |
Average price | $599 |
Good round-trip deal | $527 or less |
Good one-way deal | $331 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Santiago to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Sat 11/21
2:10 am-3:15 pm
1 stop15h 05m
Panama City Tocumen Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$337
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Wed 1/6
7:30 am-5:15 pm
1 stop11h 45m
Panama City Tocumen Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$383
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Fri 12/4
12:20 pm-5:11 pm
Nonstop6h 51m
Panama City Tocumen Intl
Fri 12/25
6:21 pm-2:48 am
Nonstop6h 27m
$640
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Sat 11/28
12:15 pm-5:11 pm
Nonstop6h 56m
Panama City Tocumen Intl
Sat 12/5
3:08 pm-11:35 pm
Nonstop6h 27m
$640
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Tue 12/1
12:20 pm-5:11 pm
Nonstop6h 51m
Panama City Tocumen Intl
Tue 12/8
11:48 am-8:11 pm
Nonstop6h 23m
$640
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Mon 12/7
12:20 pm-5:11 pm
Nonstop6h 51m
Panama City Tocumen Intl
Wed 12/16
11:48 am-8:11 pm
Nonstop6h 23m
$640
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Tue 12/1
12:20 pm-5:11 pm
Nonstop6h 51m
Panama City Tocumen Intl
Thu 12/31
6:26 pm-2:53 am
Nonstop6h 27m
$640
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Tue 12/1
5:07 am-10:03 am
Nonstop6h 56m
Panama City Tocumen Intl
Sun 12/6
7:11 pm-3:43 am
Nonstop6h 32m
$640
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Sun 11/29
5:07 am-10:03 am
Nonstop6h 56m
Panama City Tocumen Intl
Sun 12/6
7:11 pm-3:43 am
Nonstop6h 32m
$640
SantiagoPanama City
SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl
SCLPTY
Santiago Arturo Merino Benitez
Thu 12/3
5:07 am-10:03 am
Nonstop6h 56m
Panama City Tocumen Intl
Mon 12/7
7:11 pm-3:43 am
Nonstop6h 32m
$640
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Santiago to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Panama City in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santiago-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago with our price prediction graph.
SCL-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Panama City
Prices
Airlines
Delays
How far ahead should I book a flight from Santiago to Panama City?
The best time to book flights from Santiago to Panama City is 6 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Santiago to Panama City?
Currently, March is the cheapest month in which you can book a flight from Santiago to Panama City (average of $534). Flying from Santiago to Panama City in September is currently the most expensive (average of $656). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SCL to PTY?
Find hourly flight availability from Santiago to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2026.
It’s typically best to fly out from Santiago to Panama City in the afternoon. Doing so could potentially save you 53% on the flight price compared to flying in the morning, which is usually more expensive.
How often are flights from Santiago to Panama City delayed?
About 4% of weekly flights between Santiago and Panama City have experienced delays in the past year, with the average delay time being 123 minutes.
What is the most punctual flight time for Santiago to Panama City flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Santiago to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 4% of flights being delayed.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 4, 2026.
Read through reviews of airlines operating flights from Santiago to Panama City, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Entertainment
6.9
Food
7.0
Boarding
7.8
Crew
8.1
Overall
7.6
Reviews
1 / 20
4.0
OkayMarcos,Nov 2026
BOS - PTY
Comfort
7.4
Entertainment
6.9
Food
7.0
Boarding
7.8
Crew
8.1
Overall
7.6
Reviews
1 / 20
4.0
OkayMarcos,Nov 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Santiago to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santiago and Panama City flights
Browse other Santiago and Panama City flight options. Last updated on November 4, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Santiago to Panama City
Discover the top airline that operate flights from Santiago to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$436 | Average$626 | FlexibilityNo cancel fee | On-time70% |