HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$265+ Cheap flights from Santiago (SCL) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — PTY
Sep 5 — Sep 121
Sat 9/5
Sat 9/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santiago to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Panama City Tocumen Intl are usually found in November or April, booked 11 days in advance, depart on a Wednesday or Friday and return on a Thursday

Cheap flight deals from Santiago to Panama City

Cheapest flights from Santiago to Panama City
Explore the most affordable flight options available from Santiago to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.

This Avianca deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/81:30 am -
1 stop14h 45m
Fri 10/2310:10 am -
1 stop12h 10m
Deal found 8/2$580
This Avianca deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:40 am -
1 stop11h 20m
Thu 10/1510:10 am -
1 stop17h 35m
Deal found 8/3$582
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:20 pm -
1 stop10h 15m
Mon 9/2110:10 am -
1 stop12h 10m
Deal found 8/2$584
This FlightHub deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:40 am -
1 stop8h 35m
Sun 8/235:55 pm -
1 stop9h 50m
Deal found 8/2$603
This Avianca deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:30 am -
1 stop17h 30m
Tue 9/2910:10 am -
1 stop12h 10m
Deal found 8/4$617
This Copa Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:23 pm -
Nonstop6h 48m
Sun 11/1511:48 am -
Nonstop6h 27m
Deal found 8/2$620
This deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:40 am -
1 stop8h 35m
Fri 8/2110:10 am -
1 stop12h 10m
Deal found 8/4$628
This Copa Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:06 am -
Nonstop6h 49m
Tue 12/156:21 pm -
Nonstop6h 27m
Deal found 8/3$635
This Copa Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:15 am -
Nonstop6h 48m
Sun 10/253:08 pm -
Nonstop6h 31m
Deal found 8/3$640
This Copa Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/223:19 am -
Nonstop6h 57m
Mon 1/43:51 pm -
Nonstop6h 32m
Deal found 8/3$650
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:40 pm -
2 stops27h 19m
Mon 9/71:20 pm -
1 stop9h 51m
Deal found 8/3$659

Find flight deals from Santiago to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$580
(Avianca)

One-way from

$265
(Super.com)

Popular in

September

Cheapest in

November

Average price

$610

Good round-trip deal

$477 or less

Good one-way deal

$305 or less
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Panama City Tocumen Intl flights.
Search Deals
From Santiago Arturo Merino Benitez to Panama City Tocumen Intl
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals
Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Santiago to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Thu 11/5

3:48 am-8:45 am

Nonstop6h 57m

Panama City Tocumen Intl

Mon 11/16

11:48 am-8:15 pm

Nonstop6h 27m

$620
Quickest round-trip

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Sun 11/15

5:07 am-10:03 am

Nonstop6h 56m

Panama City Tocumen Intl

Tue 11/24

6:25 pm-2:48 am

Nonstop6h 23m

$620

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Tue 10/6

3:57 am-8:45 am

Nonstop6h 48m

Panama City Tocumen Intl

Wed 10/14

6:15 pm-2:46 am

Nonstop6h 31m

$640

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Fri 10/9

12:23 pm-5:11 pm

Nonstop6h 48m

Panama City Tocumen Intl

Fri 10/23

3:08 pm-11:39 pm

Nonstop6h 31m

$640

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Mon 10/12

5:15 am-10:03 am

Nonstop6h 48m

Panama City Tocumen Intl

Sun 10/25

3:08 pm-11:39 pm

Nonstop6h 31m

$640

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Wed 11/18

5:07 am-10:03 am

Nonstop6h 56m

Panama City Tocumen Intl

Sun 11/22

3:51 pm-12:19 am

Nonstop6h 28m

$640
Cheapest one-way

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Sun 1/10

4:25 pm-1:00 am

1 stop10h 35m

$277

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Sat 9/26

7:40 am-2:15 pm

1 stop8h 35m

$277

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Fri 9/4

12:30 am-5:00 pm

1 stop17h 30m

$277

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Tue 9/15

4:20 pm-12:35 am

1 stop10h 15m

$278

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/6

Showing 1-10 of 16 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santiago-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Panama City

How far ahead should I book a flight from Santiago to Panama City?

The best time to book flights from Santiago to Panama City is 10 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Panama City?

Currently, November is the cheapest month in which you can book a flight from Santiago to Panama City (average of $474). Flying from Santiago to Panama City in September is currently the most expensive (average of $672). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to PTY?

Find hourly flight availability from Santiago to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 6, 2026.

When flying from Santiago to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Santiago to Panama City?

Airfare is typical for this route at the moment.

Santiago to Panama City flights typically cost between $558 and $650 in October.
The cheapest round-trip price found within the last 5 days was $580 on Avianca (Oct 8-Oct 23).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 6, 2026.
Read through reviews of airlines operating flights from Santiago to Panama City, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,564 reviews

Boarding

7.8

Crew

8.1

Overall

7.6

Food

6.9

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class
Copa Airlines
7.6
Good
1,564 reviews
Copa Airlines
7.6
Good
1,564 reviews

Boarding

7.8

Crew

8.1

Overall

7.6

Food

6.9

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class

Related info for your journey

Find useful and relevant information for your journey from Santiago to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santiago to Panama City?

    If you book a flight from Santiago to Panama City, you will be flying from Arturo Merino Benitez to Tocumen Intl. Flights to Panama City Tocumen Intl (PTY) from Santiago Arturo Merino Benitez (SCL) take 6h 48m for a nonstop flight. There are 11 flights from Arturo Merino Benitez to Panama City per day from 1 airline.

  • How popular is this Santiago to Panama City flight route?

    This flight path from Santiago Arturo Merino Benitez to Panama City Tocumen Intl was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Panama City?

    Airlines like Avianca fly from Santiago to Panama City in about 14h 45m. The time it takes to get you to your destination can typically vary by up to . The distance between Santiago and Panama City is about 2986 mi.

  • What is the cheapest airline to fly from Santiago to Panama City round-trip?

    According to our current data, Copa Airlines ($450), offers the cheapest pricing from Santiago to Panama City. Copa Airlines is 20% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the most reliable airlines from Santiago to Panama City?

    Consider KLM (95%), United Airlines (86%) or Copa Airlines (84%) when booking your flight. These represent the most reliable airlines when flying from Santiago to Panama City.

  • What are the cheapest flights from Santiago to Panama City?

    On average you can expect to pay $1,024 for a flight from Santiago to Panama City. The cheapest flight overall is $220 while the most popular route, (Santiago Arturo Merino Benitez - Panama City Tocumen Intl) is currently priced at $580.

  • Can I find deals for flights from Santiago to Panama City that include hotel bookings?

    Yes. In addition to deals on Santiago to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Panama City.

  • Can I find deals for business class flights from Santiago to Panama City?

    Yes. Cheapflights offers flight deals from Santiago to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Panama City?

    Currently, November is the cheapest month in which you can book a flight from Santiago to Panama City (average of $474). Flying from Santiago to Panama City in September is currently the most expensive (average of $672). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Santiago to Panama City

Discover the top airline that operate flights from Santiago to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$450Average$612FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.