Question 1

What are the cheapest airlines flying from Portland, Maine to Panama City round-trip?

Accepted Answer

Currently priced at $425, Delta will fly you from Portland, Maine to Panama City and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $465.

Question 2

What is the cheapest month to book a flight from Portland, Maine to Panama City?

Accepted Answer

Currently, October is the cheapest month in which you can book a flight from Portland, Maine to Panama City (average of $478). Flying from Portland, Maine to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Question 3

What is the cheapest day to fly from Portland, Maine to Panama City?

Accepted Answer

Travelers seeking maximum savings on their Portland, Maine to Panama City flight should consider departing on Monday mornings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Question 4

E

Accepted Answer

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Question 5

E

Accepted Answer

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Question 6

What is the cheapest day to fly round-trip from Portland, Maine to Panama City?

Accepted Answer

Travelers have found that booking a Sunday departure is the best way to save up to 28% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

Question 7

What is the cheapest time of day to fly from PWM to PTY?

Accepted Answer

When flying from Portland, Maine to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Question 8

Can I find deals for flights from Portland to Panama City that include hotel bookings?

Accepted Answer

Yes. In addition to deals on Portland to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

Question 9

How can I find direct flights from Portland to Panama City?

Accepted Answer

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Panama City.

Question 10

Can I find deals for business class flights from Portland to Panama City?

Accepted Answer

Yes. Cheapflights offers flight deals from Portland to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$425	Average$711	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$465	Average$660	FlexibilityNo cancel fee	On-time69%

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Best time to book a flight from Portland to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Portland with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Portland to Panama City

What is the cheapest month to book a flight from Portland, Maine to Panama City?

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Delta and United Airlines from Portland to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Portland, Maine to Panama City round-trip?

Can I find deals for flights from Portland to Panama City that include hotel bookings?

How can I find direct flights from Portland to Panama City?

Can I find deals for business class flights from Portland to Panama City?

What is the cheapest month to book a flight from Portland, Maine to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Portland to Panama City by cabin class

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Portland and Panama City flights

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Other flights from Portland

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Other flights to Panama City

Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 14, 2025.

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Top 2 airlines flying from Portland to Panama City

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Cheap flights from Portland, ME (PWM) to Panama City (PTY)

Find cheap flights from Portland to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Best time to book a flight from Portland to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Portland with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Portland to Panama City

What is the cheapest month to book a flight from Portland, Maine to Panama City?

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Delta and United Airlines from Portland to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Portland, Maine to Panama City round-trip?

Can I find deals for flights from Portland to Panama City that include hotel bookings?

How can I find direct flights from Portland to Panama City?

Can I find deals for business class flights from Portland to Panama City?

What is the cheapest month to book a flight from Portland, Maine to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Portland to Panama City

100% Free

Book with Flexibility

Travel Smart