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$189+ Cheap flights from Columbus (CMH) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Oct 8 — Oct 151
Wed 10/8
Wed 10/15
1 adult, Economy
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Cheapflights Tip: The best prices from Columbus to Panama City Tocumen Intl are usually found in October or July, booked 16 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Columbus to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 8, 2025.

Round-trip from

$413
(United Airlines)

One-way from

$189
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$529
From Columbus to Panama City Tocumen Intl
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One-way flight from Columbus to Panama City Tocumen Intl
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Highest demand for flights based on searches. 19% potential increase in price ($148 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($39 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Columbus to Panama City

Cheapest flights from Columbus to Panama City
Explore the most affordable flight options available from Columbus to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2025.

This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:15 amCMH - PTY
1 stop8h 59mUnited Airlines
Mon 10/203:30 pmPTY - CMH
1 stop18h 29mUnited Airlines
Deal found 9/8$413
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:30 amCMH - PTY
2 stops9h 33mAmerican Airlines
Mon 10/203:15 pmPTY - CMH
2 stops18h 21mAmerican Airlines
Deal found 9/6$435
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amCMH - PTY
2 stops9h 37mAmerican Airlines
Sun 12/72:50 pmPTY - CMH
1 stop10h 05mAmerican Airlines
Deal found 9/6$440
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:37 amCMH - PTY
1 stop29h 30mUnited Airlines
Tue 12/164:41 pmPTY - CMH
2 stops20h 33mUnited Airlines
Deal found 9/7$444
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amCMH - PTY
1 stop13h 59mDelta
Sun 12/73:46 pmPTY - CMH
1 stop8h 33mDelta
Deal found 9/6$447
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amCMH - PTY
1 stop8h 12mDelta
Thu 11/273:37 pmPTY - CMH
1 stop8h 41mDelta
Deal found 9/7$461
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/244:44 pmCMH - PTY
2 stops20h 54mAmerican Airlines
Thu 11/272:43 pmPTY - CMH
2 stops19h 40mAmerican Airlines
Deal found 9/7$468
This Avianca Connect deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:15 amCMH - PTY
2 stops19h 55mMultiple Airlines
Wed 9/243:20 amPTY - CMH
2 stops15h 42mMultiple Airlines
Deal found 9/7$486
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:30 amCMH - PTY
1 stop10h 37mUnited Airlines
Fri 12/194:41 pmPTY - CMH
1 stop30h 48mUnited Airlines
Deal found 9/6$487
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:55 pmCMH - PTY
1 stop21h 08mAmerican Airlines
Thu 10/303:15 pmPTY - CMH
2 stops18h 21mAmerican Airlines
Deal found 9/6$493

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 8, 2025.
Use the filters below to find and compare flights from Columbus Airport to Panama City that are best for you.

Fly from

Columbus

Fly to

Panama City

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 10/8

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

Mon 10/20

3:30 pm-10:59 am

1 stop18h 29m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 10/21

7:05 am-12:56 pm

1 stop6h 51m

Panama City Tocumen Intl

Tue 10/28

2:21 pm-11:59 pm

1 stop8h 38m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 12/9

5:07 pm-1:48 pm

2 stops20h 41m

Panama City Tocumen Intl

Fri 12/19

2:53 pm-12:09 pm

2 stops21h 16m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 10/21

11:44 am-6:37 pm

1 stop7h 53m

Panama City Tocumen Intl

Tue 10/28

9:30 am-11:44 pm

2 stops13h 14m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 10/8

5:30 am-2:03 pm

2 stops9h 33m

Panama City Tocumen Intl

Mon 10/20

3:15 pm-10:36 am

2 stops18h 21m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 11/24

4:45 pm-7:38 pm

1 stop26h 53m

$189

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 11/24

6:00 am-2:12 pm

1 stop8h 12m

$222

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 11/24

4:44 pm-1:38 pm

2 stops20h 54m

$224

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 12/25

5:53 pm-1:53 pm

2 stops20h 00m

$401

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 11/24

10:50 am-12:40 am

3 stops13h 50m

$498

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/7

Showing 1-10 of 12 results
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Best time to book a flight from Columbus to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama City

How far ahead should I book a flight from Columbus Airport to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Columbus to Panama City. Price data was last updated on August 29, 2025.

The best time to book flights from Columbus Airport to Panama City is 12 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Columbus Airport to Panama City?

Currently, October is the cheapest month in which you can book a flight from Columbus Airport to Panama City (average of $478). Flying from Columbus Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PTY?

Find hourly flight availability from Columbus to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 8, 2025.

It’s typically best to fly out from Columbus Airport to Panama City in the afternoon. Doing so could potentially save you 20% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 8, 2025.
Read through reviews of airlines operating flights from Columbus Airport to Panama City, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,966 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,966 reviews
Delta
8.0
Very good
7,966 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,944 reviews
Delta
8.0
Very good
7,966 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,966 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Columbus?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Columbus to Panama City. 3 airlines have flights to Tocumen Intl from Columbus on a regular basis. Booking flights from Columbus to Panama City Tocumen Intl should not be difficult; the airport handles an average of 0 inbound flights from Columbus per day.

  • How long is the flight from Columbus Airport to Panama City?

    There are many flights that can get you from Columbus Airport to Panama City in 6h 51m. Fly via United Airlines or Delta to get the fastest option. There are 2146 mi between Columbus Airport and Panama City. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Columbus Airport to Panama City round-trip?

    Flying on Delta is currently your cheapest option to Panama City, with prices starting at $393. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $434 and $450, respectively. Users have found that Delta is 34% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Columbus Airport to Panama City one-way?

    $189 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $222 and $224, respectively.

  • Can I find deals for flights from Columbus to Panama City that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama City.

  • Can I find deals for business class flights from Columbus to Panama City?

    Yes. Cheapflights offers flight deals from Columbus to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Columbus Airport to Panama City (average of $478). Flying from Columbus Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Columbus to Panama City

Discover the top 3 airlines that operate flights from Columbus to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$558FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$434Average$548FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$450Average$575FlexibilityNo cancel feeOn-time71%

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