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Panama City

$179+ Cheap flights from LaGuardia, NY (LGA) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — PTY
Mar 23 — Mar 301
Mon 3/23
Mon 3/30
1 adult, Economy
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Cheap flight deals from LaGuardia to Panama City

Cheapest flights from LaGuardia to Panama City
Explore the most affordable flight options available from LaGuardia to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.

This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:59 pm
LGA
-
PTY
2 stops26h 16m
Multiple Airlines
Mon 4/203:05 am
PTY
-
LGA
2 stops31h 59m
Multiple Airlines
Deal found 2/18$415
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:59 am
LGA
-
PTY
2 stops13h 41m
Multiple Airlines
Tue 3/242:55 am
PTY
-
LGA
2 stops29h 05m
Multiple Airlines
Deal found 2/20$417
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:45 pm
LGA
-
PTY
2 stops18h 15m
Multiple Airlines
Mon 3/162:55 pm
PTY
-
LGA
2 stops17h 05m
Multiple Airlines
Deal found 2/19$423
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:45 pm
LGA
-
PTY
2 stops29h 15m
Multiple Airlines
Thu 3/122:55 am
PTY
-
LGA
2 stops15h 05m
Multiple Airlines
Deal found 2/17$426
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:30 pm
LGA
-
PTY
2 stops29h 30m
Multiple Airlines
Sun 3/222:55 am
PTY
-
LGA
3 stops27h 42m
Multiple Airlines
Deal found 2/17$428
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:59 am
LGA
-
PTY
2 stops12h 41m
Multiple Airlines
Thu 3/59:45 am
PTY
-
LGA
2 stops33h 15m
Multiple Airlines
Deal found 2/17$430
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:30 pm
LGA
-
PTY
2 stops18h 30m
Multiple Airlines
Mon 3/239:45 am
PTY
-
LGA
2 stops22h 15m
Multiple Airlines
Deal found 2/17$434
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1010:59 am
LGA
-
PTY
2 stops15h 01m
Multiple Airlines
Tue 3/172:55 pm
PTY
-
LGA
2 stops17h 05m
Multiple Airlines
Deal found 2/18$435
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:59 pm
LGA
-
PTY
2 stops21h 16m
Multiple Airlines
Mon 4/279:33 pm
PTY
-
LGA
1 stop10h 27m
Multiple Airlines
Deal found 2/18$436
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/248:45 pm
LGA
-
PTY
2 stops20h 10m
Multiple Airlines
Fri 2/279:45 am
PTY
-
LGA
2 stops33h 14m
Multiple Airlines
Deal found 2/17$442

Find flight deals from LaGuardia to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from LaGuardia (LGA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$415
(Mytrip)

One-way from

$179
(Kiwi.com)

Popular in

May

Cheapest in

March

Average price

$575
Provider with most accurate pricing for New York LaGuardia-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York LaGuardia-Panama City Tocumen Intl flights.
Search Deals
From New York LaGuardia to Panama City Tocumen Intl
Search Deals
One-way flight from New York LaGuardia to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($6 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from LaGuardia to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Panama City that are best for you.

Fly from

LaGuardia

Fly to

Panama City

Route

Depart

Return

Price

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 3/3

10:59 am-1:00 am

2 stops14h 01m

Panama City Tocumen Intl

Mon 3/9

2:55 pm-9:00 am

2 stops17h 05m

$444

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 3/3

8:45 pm-2:00 pm

2 stops17h 15m

Panama City Tocumen Intl

Tue 3/10

2:55 pm-9:00 am

2 stops17h 05m

$444

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sat 4/25

7:59 pm-9:15 am

2 stops14h 16m

Panama City Tocumen Intl

Wed 4/29

5:55 pm-9:00 am

2 stops14h 05m

$448

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 4/22

7:59 pm-2:15 pm

2 stops19h 16m

Panama City Tocumen Intl

Sun 4/26

5:55 pm-9:00 am

2 stops14h 05m

$449

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 4/9

10:59 am-1:55 am

2 stops15h 56m

Panama City Tocumen Intl

Wed 4/15

3:10 pm-9:00 am

2 stops16h 50m

$454

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Mon 3/23

8:30 pm-8:50 am

2 stops13h 20m

Panama City Tocumen Intl

Wed 3/25

2:55 pm-9:00 am

2 stops17h 05m

$460

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sun 3/22

7:59 am-1:00 am

2 stops18h 01m

Panama City Tocumen Intl

Wed 3/25

2:55 pm-9:00 am

2 stops17h 05m

$468

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 5/13

8:00 am-1:05 am

2 stops18h 05m

Panama City Tocumen Intl

Fri 5/15

3:05 am-7:04 pm

2 stops14h 59m

$470

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 3/24

8:30 pm-8:50 am

2 stops13h 20m

Panama City Tocumen Intl

Thu 3/26

5:50 pm-9:00 am

2 stops14h 10m

$470

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 4/16

7:59 pm-9:15 am

2 stops14h 16m

Panama City Tocumen Intl

Mon 4/27

3:10 pm-9:00 am

2 stops16h 50m

$471

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Showing 1-10 of 20 results
1
2

Compare providers for flights from LaGuardia to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from LaGuardia to Panama City in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on New York LaGuardia Airport-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on New York LaGuardia Airport-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from New York LaGuardia Airport-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on New York LaGuardia Airport-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New York LaGuardia Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from LaGuardia to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from LaGuardia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 21, 2026.
Peruse reviews from past customers who have flown with American Airlines from New York LaGuardia Airport to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,334 reviews

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,334 reviews
American Airlines
7.2
Good
11,334 reviews

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from LaGuardia to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from New York LaGuardia?

    Most people fly into Panama City Tocumen Intl (PTY) if they book a flight to Panama City from New York LaGuardia. On average, Tocumen Intl has 0 inbound flights from New York LaGuardia per day from 1 airline. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • What is the cheapest airline to fly from New York LaGuardia Airport to Panama City round-trip?

    Currently priced at $225, American Airlines will fly you from New York LaGuardia Airport to Panama City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. This flight start at 59% lower than the current average price 3 months from now.

  • Can I find deals for flights from LaGuardia to Panama City that include hotel bookings?

    Yes. In addition to deals on LaGuardia to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from LaGuardia to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from LaGuardia to Panama City.

  • Can I find deals for business class flights from LaGuardia to Panama City?

    Yes. Cheapflights offers flight deals from LaGuardia to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for LaGuardia to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Panama City flights
Newark to Panama City flights
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Stewart to Panama City flights

Top airline flying from LaGuardia to Panama City

Discover the top airline that operate flights from LaGuardia to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$225Average$383FlexibilityNo cancel feeOn-time71%

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