$187+ Cheap flights from Houston to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — PTY
Mar 18 — Mar 251
1 adult, Economy
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Find cheap flights from Houston to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Panama City
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Cheapest flights from Houston to Panama CityExplore the most affordable flight options available from Houston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 16, 2026.
Explore the most affordable flight options available from Houston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Tue 4/1410:10 am
PTY
- IAH
2 stops13h 39m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Wed 4/155:30 am
PTY
- IAH
3 stops12h 30m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$445
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Thu 4/1610:10 am
PTY
- IAH
2 stops12h 39m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$446
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Wed 4/155:30 am
PTY
- IAH
3 stops12h 30m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$447
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Sat 4/185:30 am
PTY
- IAH
2 stops12h 30m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Fri 4/1710:10 am
PTY
- IAH
2 stops12h 39m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Sat 4/185:30 am
PTY
- IAH
2 stops12h 30m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$450
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Wed 4/85:30 am
PTY
- IAH
1 stop8h 19m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$466
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:30 pm
IAH
- PTY
1 stop15h 36m
Multiple Airlines
Tue 5/123:10 pm
PTY
- IAH
2 stops16h 58m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$467
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:24 am
IAH
- PTY
1 stop9h 56m
Multiple Airlines
Thu 5/145:30 am
PTY
- IAH
3 stops18h 09m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:24 am
IAH
- PTY
1 stop9h 56m
Multiple Airlines
Thu 5/2810:10 am
PTY
- IAH
2 stops13h 29m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$469
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:45 pm
IAH
- PTY
1 stop8h 10m
Multiple Airlines
Sat 4/185:30 am
PTY
- IAH
2 stops12h 30m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$470
Best flights from Houston to Panama CityDiscover carefully curated flight deals from Houston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 16, 2026.
Discover carefully curated flight deals from Houston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Tue 4/1410:10 am
PTY
- IAH
2 stops13h 39m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
HOU
- PTY
1 stop6h 55m
Delta
Wed 5/272:20 pm
PTY
- HOU
1 stop8h 48m
Delta
Deal found 2/13![Delta logo]()
$785
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:22 pm
HOU
- PTY
2 stops15h 48m
American Airlines
Tue 8/113:20 pm
PTY
- HOU
2 stops17h 01m
American Airlines
Deal found 2/15![American Airlines logo]()
$789
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:45 am
IAH
- PTY
2 stops14h 30m
Multiple Airlines
Tue 4/79:33 pm
PTY
- IAH
1 stop26h 16m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$490
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Mon 4/69:33 pm
PTY
- IAH
1 stop26h 16m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$496
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:43 am
IAH
- PTY
1 stop7h 37m
Multiple Airlines
Sun 5/33:41 pm
PTY
- IAH
1 stop7h 58m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$518
This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:24 pm
IAH
- PTY
2 stops23h 31m
Multiple Airlines
Tue 4/2810:10 am
PTY
- IAH
3 stops34h 22m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$520
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Mon 4/69:33 pm
PTY
- IAH
2 stops25h 17m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$525
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:19 pm
HOU
- PTY
2 stops20h 27m
American Airlines
Wed 5/271:14 pm
PTY
- HOU
2 stops19h 43m
American Airlines
Deal found 2/13![American Airlines logo]()
$789
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
HOU
- PTY
1 stop7h 03m
Delta
Tue 4/142:27 pm
PTY
- HOU
1 stop19h 31m
Delta
Deal found 2/14![Delta logo]()
$797
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:20 pm
HOU
- PTY
2 stops16h 20m
American Airlines
Wed 4/81:49 pm
PTY
- HOU
2 stops19h 37m
American Airlines
Deal found 2/13![American Airlines logo]()
$789
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:24 pm
IAH
- PTY
1 stop14h 42m
Multiple Airlines
Mon 3/169:33 pm
PTY
- IAH
2 stops12h 51m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:20 pm
HOU
- PTY
2 stops16h 20m
American Airlines
Tue 4/281:49 pm
PTY
- HOU
2 stops19h 37m
American Airlines
Deal found 2/13![American Airlines logo]()
$789
This Mytrip deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:00 pm
IAH
- PTY
3 stops26h 55m
Multiple Airlines
Sun 3/152:55 am
PTY
- IAH
3 stops35h 10m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$568
This Mytrip deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:15 am
IAH
- PTY
3 stops19h 45m
Multiple Airlines
Mon 3/303:05 am
PTY
- IAH
2 stops20h 54m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$570
This Booking.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:24 pm
IAH
- PTY
2 stops20h 51m
Multiple Airlines
Mon 4/610:25 am
PTY
- IAH
3 stops37h 46m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$570
This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:47 pm
IAH
- PTY
2 stops26h 13m
Multiple Airlines
Mon 5/253:10 pm
PTY
- IAH
2 stops22h 07m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$591
Last-minute flights from Houston to Panama CityDiscover last-minute flight deals from Houston to Panama City. Data last updated February 16, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Panama City. Data last updated February 16, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:40 pm
IAH
- PTY
2 stops31h 53m
Multiple Airlines
Wed 4/15:30 am
PTY
- IAH
1 stop8h 19m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$507
This Mytrip deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:47 pm
IAH
- PTY
3 stops32h 53m
Multiple Airlines
Sat 2/289:45 am
PTY
- IAH
2 stops15h 14m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:46 am
IAH
- PTY
1 stop13h 33m
Multiple Airlines
Tue 3/1012:03 pm
PTY
- IAH
1 stop8h 20m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$503
This Mytrip deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:24 pm
IAH
- PTY
2 stops23h 31m
Multiple Airlines
Mon 3/303:10 pm
PTY
- IAH
2 stops32h 39m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$495
This Mytrip deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:24 pm
IAH
- PTY
2 stops20h 36m
Multiple Airlines
Sun 3/222:55 am
PTY
- IAH
3 stops43h 15m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:24 pm
IAH
- PTY
2 stops15h 26m
Multiple Airlines
Wed 4/15:30 am
PTY
- IAH
1 stop8h 19m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$480
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:45 am
IAH
- PTY
2 stops14h 30m
Multiple Airlines
Tue 4/79:33 pm
PTY
- IAH
1 stop26h 16m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$490
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:24 pm
IAH
- PTY
2 stops15h 26m
Multiple Airlines
Tue 4/286:34 pm
PTY
- IAH
1 stop13h 34m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$475
This BusinessClass deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:00 am
HOU
- PTY
1 stop7h 03m
LATAM Airlines
Tue 4/282:27 pm
PTY
- HOU
1 stop8h 38m
LATAM Airlines
Deal found 2/13![LATAM Airlines logo]()
$785
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:20 pm
HOU
- PTY
2 stops16h 20m
American Airlines
Tue 4/281:49 pm
PTY
- HOU
2 stops19h 37m
American Airlines
Deal found 2/13![American Airlines logo]()
$789
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:36 am
IAH
- PTY
1 stop10h 43m
Multiple Airlines
Tue 3/3112:03 pm
PTY
- IAH
1 stop11h 56m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$502
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:24 pm
IAH
- PTY
2 stops15h 51m
Multiple Airlines
Mon 4/69:33 pm
PTY
- IAH
1 stop26h 16m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$474
One-way flights from Houston to Panama CitySearch for one-way flight options from Houston to Panama City. Find affordable one-way fares based on user searches. Data last updated February 16, 2026.
Search for one-way flight options from Houston to Panama City. Find affordable one-way fares based on user searches. Data last updated February 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:29 pm
IAH
- PTY
1 stop10h 26m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:39 pm
IAH
- PTY
2 stops18h 36m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:39 pm
IAH
- PTY
2 stops23h 36m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:24 pm
IAH
- PTY
2 stops15h 51m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:24 pm
IAH
- PTY
2 stops15h 26m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:24 pm
IAH
- PTY
2 stops20h 36m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:19 pm
IAH
- PTY
3 stops32h 36m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:18 pm
HOU
- PTY
2 stops20h 28m
American Airlines
Deal found 2/15![American Airlines logo]()
$662
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:20 pm
HOU
- PTY
2 stops20h 20m
American Airlines
Deal found 2/15![American Airlines logo]()
$670
This BusinessClass deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
HOU
- PTY
1 stop7h 03m
LATAM Airlines
Deal found 2/15![LATAM Airlines logo]()
$700
This BusinessClass deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
HOU
- PTY
1 stop6h 55m
LATAM Airlines
Deal found 2/15![LATAM Airlines logo]()
$724
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:19 pm
HOU
- PTY
2 stops20h 27m
American Airlines
Deal found 2/15![American Airlines logo]()
$725
Find flight deals from Houston to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 16, 2026.
Round-trip from | $443 (Kiwi.com) |
|---|---|
One-way from | $187 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $893 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
Use the filters below to find and compare flights from Houston to Panama City that are best for you.
Fly from
Houston
Fly to
Panama City
Route
Depart
Return
Price
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 4/6
3:29 pm-1:55 am
1 stop10h 26m
Panama City Tocumen Intl
Tue 4/14
10:10 am-11:49 pm
2 stops13h 39m
$443
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Wed 3/18
5:45 am-8:15 pm
2 stops14h 30m
Panama City Tocumen Intl
Tue 4/7
9:33 pm-11:49 pm
1 stop26h 16m
$490
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Wed 4/1
3:29 pm-1:55 am
1 stop10h 26m
Panama City Tocumen Intl
Mon 4/6
9:33 pm-11:49 pm
1 stop26h 16m
$496
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 4/27
11:43 am-7:20 pm
1 stop7h 37m
Panama City Tocumen Intl
Sun 5/3
3:41 pm-11:39 pm
1 stop7h 58m
$518
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Wed 3/25
5:24 pm-4:55 pm
2 stops23h 31m
Panama City Tocumen Intl
Tue 4/28
10:10 am-8:32 pm
3 stops34h 22m
$520
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Fri 4/3
3:29 pm-1:55 am
1 stop10h 26m
Panama City Tocumen Intl
Mon 4/6
9:33 pm-10:50 pm
2 stops25h 17m
$525
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Fri 3/13
5:24 pm-8:06 am
1 stop14h 42m
Panama City Tocumen Intl
Mon 3/16
9:33 pm-10:24 am
2 stops12h 51m
$557
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 3/12
2:00 pm-4:55 pm
3 stops26h 55m
Panama City Tocumen Intl
Sun 3/15
2:55 am-2:05 pm
3 stops35h 10m
$568
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 3/26
5:15 am-1:00 am
3 stops19h 45m
Panama City Tocumen Intl
Mon 3/30
3:05 am-11:59 pm
2 stops20h 54m
$570
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 3/30
5:24 pm-2:15 pm
2 stops20h 51m
Panama City Tocumen Intl
Mon 4/6
10:25 am-12:11 am
3 stops37h 46m
$570
Showing 1-10 of 33 results
Best time to book a flight from Houston to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Houston with our price prediction graph.
HO1-PTY
IAH-PTY
HOU-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Panama City
HO1-PTY
IAH-PTY
HOU-PTY
How far ahead should I book a flight from Houston to Panama City?
Use this chart to determine the optimal time to book a round-trip flight from Houston to Panama City. Price data was last updated on February 13, 2026.
The price you pay for your flight from Houston to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Houston to Panama City?
Currently, March is the cheapest month in which you can book a flight from Houston to Panama City (average of $559). Flying from Houston to Panama City in October is currently the most expensive (average of $779). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from HOU to PTY?
Find hourly flight availability from Houston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 16, 2026.
When flying from Houston to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from Houston to Panama City delayed?
About 17% of weekly flights between Houston and Panama City have experienced delays in the past year, with the average delay time being 148 minutes.
What is the most punctual flight time for Houston to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Houston to Panama City flights?
Over the last year, United Airlines have had the lowest number of delays on this route, with just 17% of flights being delayed.
The best insider tips for Houston to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Houston to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 16, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Houston to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Boarding
7.8
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Boarding
7.8
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from Houston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Search flights from Houston to Panama City by cabin class
Find flights from Houston to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Houston and Panama City flights
Browse other Houston and Panama City flight options. Last updated on February 16, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Houston to Panama City
Discover the top 2 airlines that operate flights from Houston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$555 | Average$815 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$738 | Average$899 | FlexibilityNo cancel fee | On-time69% |