$158+ Cheap flights from Houston to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — PTY
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from Houston to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Panama City
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Cheapest flights from Houston to Panama CityExplore the most affordable flight options available from Houston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Houston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:24 pm
IAH
- PTY
1 stop13h 42m
Multiple Airlines
Tue 3/1010:25 am
PTY
- IAH
1 stop13h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$447
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:24 pm
IAH
- PTY
1 stop14h 42m
Multiple Airlines
Tue 4/143:41 pm
PTY
- IAH
1 stop8h 08m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:35 pm
IAH
- PTY
1 stop16h 55m
Multiple Airlines
Mon 3/99:45 am
PTY
- IAH
2 stops26h 39m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$450
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:24 pm
IAH
- PTY
1 stop14h 42m
Multiple Airlines
Wed 4/1510:25 am
PTY
- IAH
1 stop13h 26m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$453
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:24 pm
IAH
- PTY
1 stop14h 16m
Multiple Airlines
Wed 2/2510:25 am
PTY
- IAH
1 stop14h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$457
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:38 pm
IAH
- PTY
3 stops22h 22m
Multiple Airlines
Mon 5/185:55 pm
PTY
- IAH
2 stops29h 56m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:24 pm
IAH
- PTY
1 stop14h 42m
Multiple Airlines
Wed 3/1810:25 am
PTY
- IAH
1 stop13h 24m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:24 pm
IAH
- PTY
1 stop14h 16m
Multiple Airlines
Sat 2/2810:25 am
PTY
- IAH
1 stop8h 05m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:35 am
IAH
- PTY
1 stop10h 02m
Multiple Airlines
Tue 3/313:41 pm
PTY
- IAH
1 stop8h 08m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
HOU
- PTY
1 stop6h 55m
Delta
Wed 5/272:20 pm
PTY
- HOU
1 stop8h 48m
Delta
Deal found 2/1![Delta logo]()
$775
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:20 pm
HOU
- PTY
2 stops20h 20m
American Airlines
Wed 3/183:10 pm
PTY
- HOU
2 stops18h 33m
American Airlines
Deal found 2/1![American Airlines logo]()
$779
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:20 pm
HOU
- PTY
2 stops17h 55m
American Airlines
Tue 3/313:51 pm
PTY
- HOU
2 stops17h 52m
American Airlines
Deal found 2/1![American Airlines logo]()
$799
Best flights from Houston to Panama CityDiscover carefully curated flight deals from Houston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Houston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:40 pm
IAH
- PTY
3 stops26h 00m
Multiple Airlines
Tue 3/313:10 pm
PTY
- IAH
2 stops32h 39m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$490
This Trip.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:45 pm
IAH
- PTY
2 stops20h 30m
Avianca
Sun 5/245:55 pm
PTY
- IAH
2 stops22h 15m
Avianca
Deal found 1/31![Avianca logo]()
$610
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:25 am
HOU
- PTY
1 stop7h 25m
Delta
Tue 3/102:28 pm
PTY
- HOU
1 stop8h 14m
Delta
Deal found 2/2![Delta logo]()
$775
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:20 pm
HOU
- PTY
2 stops20h 20m
American Airlines
Wed 3/183:10 pm
PTY
- HOU
2 stops18h 33m
American Airlines
Deal found 2/1![American Airlines logo]()
$779
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:37 am
IAH
- PTY
2 stops21h 38m
Multiple Airlines
Mon 5/43:10 pm
PTY
- IAH
2 stops32h 41m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$523
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/155:24 pm
IAH
- PTY
2 stops19h 36m
Multiple Airlines
Mon 2/237:50 pm
PTY
- IAH
3 stops29h 09m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$527
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:24 am
IAH
- PTY
1 stop9h 56m
Multiple Airlines
Mon 5/189:33 pm
PTY
- IAH
1 stop10h 46m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$530
This Avianca deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:45 pm
IAH
- PTY
1 stop8h 10m
Avianca
Tue 5/265:55 pm
PTY
- IAH
2 stops18h 10m
Avianca
Deal found 1/31![Avianca logo]()
$643
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:45 pm
IAH
- PTY
1 stop8h 10m
Avianca
Sun 6/285:30 am
PTY
- IAH
1 stop10h 40m
Avianca
Deal found 2/2![Avianca logo]()
$643
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:24 pm
IAH
- PTY
1 stop15h 06m
Multiple Airlines
Mon 3/2310:25 am
PTY
- IAH
1 stop13h 24m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$541
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
HOU
- PTY
1 stop7h 03m
Delta
Tue 3/242:28 pm
PTY
- HOU
1 stop8h 14m
Delta
Deal found 2/1![Delta logo]()
$775
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:05 pm
IAH
- PTY
1 stop11h 50m
Avianca
Wed 7/223:05 am
PTY
- IAH
2 stops13h 05m
Avianca
Deal found 2/2![Avianca logo]()
$643
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:20 pm
HOU
- PTY
2 stops18h 41m
American Airlines
Wed 4/81:49 pm
PTY
- HOU
2 stops19h 37m
American Airlines
Deal found 2/1![American Airlines logo]()
$779
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:45 am
IAH
- PTY
3 stops19h 20m
Multiple Airlines
Tue 4/285:30 am
PTY
- IAH
3 stops15h 08m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:20 pm
HOU
- PTY
2 stops17h 55m
American Airlines
Tue 3/313:51 pm
PTY
- HOU
2 stops17h 52m
American Airlines
Deal found 2/1![American Airlines logo]()
$799
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
HOU
- PTY
1 stop7h 03m
Delta
Sat 4/182:27 pm
PTY
- HOU
1 stop8h 39m
Delta
Deal found 2/2![Delta logo]()
$800
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:25 am
HOU
- PTY
1 stop7h 25m
Delta
Tue 3/312:28 pm
PTY
- HOU
1 stop8h 14m
Delta
Deal found 2/1![Delta logo]()
$800
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:15 am
IAH
- PTY
3 stops34h 40m
Multiple Airlines
Mon 3/92:55 am
PTY
- IAH
3 stops41h 28m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$614
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
HOU
- PTY
1 stop7h 03m
Delta
Fri 4/172:27 pm
PTY
- HOU
1 stop8h 39m
Delta
Deal found 2/2![Delta logo]()
$800
This Avianca Connect deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:05 pm
IAH
- PTY
1 stop11h 50m
Multiple Airlines
Sat 7/115:30 am
PTY
- IAH
1 stop9h 07m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$635
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
HOU
- PTY
1 stop7h 03m
Delta
Fri 4/172:27 pm
PTY
- HOU
1 stop8h 39m
Delta
Deal found 2/2![Delta logo]()
$800
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
HOU
- PTY
1 stop7h 03m
Delta
Sat 4/182:27 pm
PTY
- HOU
1 stop8h 39m
Delta
Deal found 2/2![Delta logo]()
$800
Last-minute flights from Houston to Panama CityDiscover last-minute flight deals from Houston to Panama City. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Panama City. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:24 pm
IAH
- PTY
1 stop14h 16m
Multiple Airlines
Sat 2/2810:25 am
PTY
- IAH
1 stop8h 05m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:24 pm
IAH
- PTY
1 stop14h 16m
Multiple Airlines
Wed 2/2510:25 am
PTY
- IAH
1 stop14h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:24 pm
IAH
- PTY
1 stop13h 42m
Multiple Airlines
Thu 2/263:39 pm
PTY
- IAH
1 stop9h 20m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$467
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
IAH
- PTY
2 stops12h 20m
Multiple Airlines
Sat 2/2810:25 am
PTY
- IAH
1 stop8h 05m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$470
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:35 am
IAH
- PTY
1 stop10h 02m
Multiple Airlines
Tue 3/313:41 pm
PTY
- IAH
1 stop8h 08m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$465
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:20 pm
HOU
- PTY
2 stops17h 55m
American Airlines
Tue 3/313:51 pm
PTY
- HOU
2 stops17h 52m
American Airlines
Deal found 2/1![American Airlines logo]()
$799
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:25 am
HOU
- PTY
1 stop7h 25m
Delta
Tue 3/312:28 pm
PTY
- HOU
1 stop8h 14m
Delta
Deal found 2/1![Delta logo]()
$800
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:35 pm
IAH
- PTY
1 stop16h 55m
Multiple Airlines
Mon 3/99:45 am
PTY
- IAH
2 stops26h 39m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$450
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:24 pm
IAH
- PTY
1 stop13h 42m
Multiple Airlines
Tue 3/1010:25 am
PTY
- IAH
1 stop13h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:25 am
HOU
- PTY
1 stop7h 25m
Delta
Tue 3/102:28 pm
PTY
- HOU
1 stop8h 14m
Delta
Deal found 2/2![Delta logo]()
$775
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:24 pm
IAH
- PTY
1 stop14h 42m
Multiple Airlines
Wed 3/1810:25 am
PTY
- IAH
1 stop13h 24m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$461
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:20 pm
HOU
- PTY
2 stops20h 20m
American Airlines
Wed 3/183:10 pm
PTY
- HOU
2 stops18h 33m
American Airlines
Deal found 2/1![American Airlines logo]()
$779
One-way flights from Houston to Panama CitySearch for one-way flight options from Houston to Panama City. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Houston to Panama City. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:17 am
IAH
- PTY
2 stops20h 33m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:37 pm
IAH
- PTY
2 stops21h 23m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:24 pm
IAH
- PTY
3 stops31h 16m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/249:40 pm
IAH
- PTY
2 stops18h 36m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:40 pm
IAH
- PTY
2 stops31h 53m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:24 pm
IAH
- PTY
2 stops15h 26m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:49 pm
IAH
- PTY
3 stops20h 26m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$196
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:22 pm
IAH
- PTY
3 stops40h 53m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$199
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:21 pm
HOU
- PTY
2 stops20h 19m
American Airlines
Deal found 2/2![American Airlines logo]()
$660
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/34:21 pm
HOU
- PTY
2 stops20h 19m
American Airlines
Deal found 2/1![American Airlines logo]()
$673
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:20 pm
HOU
- PTY
2 stops20h 20m
American Airlines
Deal found 1/31![American Airlines logo]()
$682
This KAYAK deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:20 pm
HOU
- PTY
2 stops17h 55m
GOL
Deal found 1/31![GOL logo]()
$701
Find flight deals from Houston to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.
Round-trip from | $447 (Kiwi.com) |
|---|---|
One-way from | $158 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $900 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Houston to Panama City that are best for you.
Fly from
Houston
Fly to
Panama City
Route
Depart
Return
Price
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sun 3/1
9:40 pm-12:40 am
3 stops26h 00m
Panama City Tocumen Intl
Tue 3/31
3:10 pm-11:49 pm
2 stops32h 39m
$490
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 4/27
11:37 am-9:15 am
2 stops21h 38m
Panama City Tocumen Intl
Mon 5/4
3:10 pm-11:51 pm
2 stops32h 41m
$523
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sun 2/15
5:24 pm-2:00 pm
2 stops19h 36m
Panama City Tocumen Intl
Mon 2/23
7:50 pm-11:59 pm
3 stops29h 09m
$527
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 5/11
9:24 am-7:20 pm
1 stop9h 56m
Panama City Tocumen Intl
Mon 5/18
9:33 pm-8:19 am
1 stop10h 46m
$530
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Fri 3/13
5:24 pm-8:30 am
1 stop15h 06m
Panama City Tocumen Intl
Mon 3/23
10:25 am-11:49 pm
1 stop13h 24m
$541
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 4/13
5:45 am-1:05 am
3 stops19h 20m
Panama City Tocumen Intl
Tue 4/28
5:30 am-8:38 pm
3 stops15h 08m
$586
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 5/21
5:45 pm-2:15 pm
2 stops20h 30m
Panama City Tocumen Intl
Sun 5/24
5:55 pm-4:10 pm
2 stops22h 15m
$610
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Fri 3/6
5:15 am-4:55 pm
3 stops34h 40m
Panama City Tocumen Intl
Mon 3/9
2:55 am-8:23 pm
3 stops41h 28m
$614
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 7/2
2:05 pm-1:55 am
1 stop11h 50m
Panama City Tocumen Intl
Sat 7/11
5:30 am-2:37 pm
1 stop9h 07m
$635
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 5/18
5:45 pm-1:55 am
1 stop8h 10m
Panama City Tocumen Intl
Tue 5/26
5:55 pm-12:05 pm
2 stops18h 10m
$643
Showing 1-10 of 42 results
Best time to book a flight from Houston to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Houston with our price prediction graph.
HO1-PTY
IAH-PTY
HOU-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Panama City
HO1-PTY
IAH-PTY
HOU-PTY
How far ahead should I book a flight from Houston to Panama City?
Use this chart to determine the optimal time to book a round-trip flight from Houston to Panama City. Price data was last updated on January 30, 2026.
The price you pay for your flight from Houston to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Houston to Panama City?
Currently, May is the cheapest month in which you can book a flight from Houston to Panama City (average of $532). Flying from Houston to Panama City in December is currently the most expensive (average of $778). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from HOU to PTY?
Find hourly flight availability from Houston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.
When flying from Houston to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Houston to Panama City?
How often are flights from Houston to Panama City delayed?
About 18% of weekly flights between Houston and Panama City have experienced delays in the past year, with the average delay time being 151 minutes.
What is the most punctual flight time for Houston to Panama City flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Houston to Panama City flights?
Over the last year, United Airlines have had the lowest number of delays on this route, with just 18% of flights being delayed.
The best insider tips for Houston to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Houston to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 3, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Houston to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Overall
7.5
Crew
8.1
Comfort
7.4
Food
6.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Boarding
7.8
Overall
7.5
Crew
8.1
Comfort
7.4
Food
6.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Boarding
7.8
Overall
7.5
Crew
8.1
Comfort
7.4
Food
6.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from Houston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Houston to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Houston to Panama City
Discover the top 2 airlines that operate flights from Houston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$555 | Average$764 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$738 | Average$899 | FlexibilityNo cancel fee | On-time69% |