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Panama City

$165+ Cheap flights from Houston to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — PTY
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Houston to Panama City Tocumen Intl are usually found in January or June, booked 86 days in advance, depart on a Saturday or Tuesday and return on a Saturday

Cheap flight deals from Houston to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$412
(Kiwi.com)

One-way from

$165
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$906
From Houston to Panama City Tocumen Intl
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One-way flight from Houston to Panama City Tocumen Intl
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Highest demand for flights based on searches. 4% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Houston to Panama City

Cheapest flights from Houston to Panama City
Explore the most affordable flight options available from Houston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2912:47 pmIAH - PTY
1 stop7h 32mMultiple Airlines
Thu 10/212:03 pmPTY - IAH
1 stop10h 39mMultiple Airlines
Deal found 9/13$412
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:55 amIAH - PTY
1 stop8h 25mMultiple Airlines
Sun 11/29:33 pmPTY - IAH
1 stop13h 27mMultiple Airlines
Deal found 9/13$415
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2010:55 amIAH - PTY
1 stop8h 34mMultiple Airlines
Thu 10/239:33 pmPTY - IAH
1 stop12h 27mMultiple Airlines
Deal found 9/14$419
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:55 amIAH - PTY
1 stop8h 34mMultiple Airlines
Sun 10/199:33 pmPTY - IAH
1 stop12h 27mMultiple Airlines
Deal found 9/15$420
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:45 amIAH - PTY
3 stops30h 50mMultiple Airlines
Mon 10/2010:05 pmPTY - IAH
3 stops23h 12mMultiple Airlines
Deal found 9/13$429
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:35 amIAH - PTY
1 stop10h 01mMultiple Airlines
Sun 11/99:33 pmPTY - IAH
1 stop13h 27mMultiple Airlines
Deal found 9/13$434
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:43 pmIAH - PTY
1 stop13h 28mMultiple Airlines
Sun 11/29:33 pmPTY - IAH
1 stop13h 27mMultiple Airlines
Deal found 9/13$435
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2710:54 amIAH - PTY
1 stop8h 35mMultiple Airlines
Thu 10/29:33 pmPTY - IAH
1 stop12h 21mMultiple Airlines
Deal found 9/13$437
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/258:00 pmIAH - PTY
1 stop12h 11mMultiple Airlines
Sat 11/89:43 pmPTY - IAH
1 stop11h 49mMultiple Airlines
Deal found 9/14$439
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1410:12 amIAH - PTY
2 stops13h 58mMultiple Airlines
Sun 10/127:55 amPTY - IAH
1 stop8h 30mMultiple Airlines
Deal found 9/12$442
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amHOU - PTY
1 stop6h 56mDelta
Tue 11/43:21 pmPTY - HOU
1 stop8h 39mDelta
Deal found 9/13$743
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:39 pmHOU - PTY
2 stops19h 24mAmerican Airlines
Fri 10/243:15 pmPTY - HOU
2 stops17h 13mAmerican Airlines
Deal found 9/14$758

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Houston to Panama City that are best for you.

Fly from

Houston

Fly to

Panama City

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Sun 10/12

6:43 pm-12:35 pm

3 stops17h 52m

Panama City Tocumen Intl

Thu 10/16

10:05 pm-12:28 am

3 stops26h 23m

$560

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Sat 10/11

6:35 am-7:29 pm

1 stop12h 54m

Panama City Tocumen Intl

Sat 10/18

12:48 pm-9:17 pm

1 stop8h 29m

$563

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 10/30

8:10 pm-7:25 pm

2 stops23h 15m

Panama City Tocumen Intl

Sun 11/2

2:55 pm-12:28 am

3 stops34h 33m

$578

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 2/11

9:47 am-10:20 am

1 stop23h 33m

Panama City Tocumen Intl

Wed 2/18

3:35 pm-4:57 pm

1 stop26h 22m

$624

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 10/14

2:05 pm-12:35 pm

2 stops22h 30m

Panama City Tocumen Intl

Thu 10/23

3:20 am-4:10 pm

2 stops12h 50m

$667

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 10/13

2:20 pm-6:37 pm

Nonstop4h 17m

Panama City Tocumen Intl

Mon 10/20

3:30 pm-7:50 pm

Nonstop4h 20m

$739

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 2/16

9:34 am-2:45 pm

Nonstop4h 11m

Panama City Tocumen Intl

Mon 2/23

8:55 am-12:14 pm

Nonstop4h 19m

$739

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 10/29

9:34 am-1:45 pm

Nonstop4h 11m

Panama City Tocumen Intl

Thu 11/13

4:41 pm-8:10 pm

Nonstop4h 29m

$739

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 3/4

11:56 am-5:07 pm

Nonstop4h 11m

Panama City Tocumen Intl

Wed 3/11

11:35 am-3:59 pm

Nonstop4h 24m

$739

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 10/28

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Tue 11/4

3:21 pm-11:00 pm

1 stop8h 39m

$743

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 43 results
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The best insider tips for Houston to Panama City flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Houston to Panama City trip
Airports
IAH

Check security wait times on the IAH website to save time before departure.

Read more about IAHby Evie Carrick
PTY

Use Uber for quick and cost-effective transport from PTY to Panama City.

Read more about PTYby Taryn White
Our travel experts
Evie Carrick

Evie Carrick

Expert on IAH

Evie Carrick

Evie Carrick

Evie Carrick is a writer and editor who has lived in five countries and traveled to over 50, with extensive experience flying around the world. She was born in Colorado, but has spent time flying to both coasts to visit family. She writes regularly for Travel + Leisure, BuzzFeed, and SKI and recently published seven travel journals with Simon & Schuster.

Read more
Taryn White

Taryn White

Expert on PTY

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more

Best time to book a flight from Houston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Panama City

How far ahead should I book a flight from Houston to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Houston to Panama City. Price data was last updated on September 12, 2025.

The price you pay for your flight from Houston to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Houston to Panama City?

Currently, October is the cheapest month in which you can book a flight from Houston to Panama City (average of $478). Flying from Houston to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to PTY?

Find hourly flight availability from Houston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

One of the essential ways to save on airfare from Houston to Panama City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 62% on airfare.

How much does it cost to fly round-trip from Houston to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, United Airlines, and Avianca from Houston to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
United Airlines
7.4
Good
8,929 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Comfort

7.4

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Houston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Houston?

    For a flight from Houston to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from Houston per day. 3 airlines have flights to Panama City Tocumen Intl from Houston on a regular basis.

  • How long is the flight from Houston to Panama City?

    Departing from Houston to Panama City will take you 6h 56m. The distance between Houston and Panama City is about 1753 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Houston to Panama City round-trip?

    Our cheapest airline available from Houston to Panama City is Avianca. Our recent data shows that you can find tickets from as low as $318 on this airline. Additional options worth looking into are United Airlines and Copa Airlines, starting at $738 and $824 round-trip. Avianca is currently priced 64% below the average price you’ll pay for this route.

  • Can I find deals for flights from Houston to Panama City that include hotel bookings?

    Yes. In addition to deals on Houston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Panama City.

  • Can I find deals for business class flights from Houston to Panama City?

    Yes. Cheapflights offers flight deals from Houston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Houston to Panama City (average of $478). Flying from Houston to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Houston to Panama City

Discover the top 3 airlines that operate flights from Houston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$318Average$565FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$738Average$895FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$824Average$1,078FlexibilityNo cancel feeOn-time70%

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