$165+ Cheap flights from Guayaquil (GYE) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Guayaquil to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guayaquil to Panama City
Cheapest flights from Guayaquil to Panama CityExplore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
Explore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
This Avianca deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Copa Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Copa Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from Guayaquil to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $287 (Avianca) |
One-way from | $165 (Super.com) |
Popular in | December |
Cheapest in | May |
Average price | $341 |
Good round-trip deal | $383 or less |
Good one-way deal | $246 or less |
Cheapflights Fare Finder
Use the filters below to find and compare flights from Guayaquil to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Thu 2/12
6:33 pm-8:41 pm
Nonstop2h 08m
Panama City Tocumen Intl
Mon 2/16
9:02 am-11:18 am
Nonstop2h 16m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Fri 2/13
5:29 am-7:39 am
Nonstop2h 10m
Panama City Tocumen Intl
Fri 2/13
9:40 pm-11:55 pm
Nonstop2h 15m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Mon 2/23
12:20 pm-2:28 pm
Nonstop2h 08m
Panama City Tocumen Intl
Mon 2/23
9:40 pm-11:55 pm
Nonstop2h 15m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Fri 2/20
6:33 pm-8:41 pm
Nonstop2h 08m
Panama City Tocumen Intl
Mon 2/23
9:40 pm-11:55 pm
Nonstop2h 15m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Fri 2/20
6:33 pm-8:41 pm
Nonstop2h 08m
Panama City Tocumen Intl
Sun 2/22
11:17 am-1:34 pm
Nonstop2h 17m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sun 2/8
5:29 am-7:39 am
Nonstop2h 10m
Panama City Tocumen Intl
Sun 2/15
6:27 pm-8:46 pm
Nonstop2h 19m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Fri 2/13
5:29 am-7:39 am
Nonstop2h 10m
Panama City Tocumen Intl
Mon 2/16
9:02 am-11:18 am
Nonstop2h 16m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Mon 2/9
6:33 pm-8:41 pm
Nonstop2h 08m
Panama City Tocumen Intl
Tue 2/10
9:02 am-11:18 am
Nonstop2h 16m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Sat 2/21
5:29 am-7:39 am
Nonstop2h 10m
Panama City Tocumen Intl
Mon 2/23
9:40 pm-11:55 pm
Nonstop2h 15m
GuayaquilPanama City
GYE - PTY
GYEPTY
Guayaquil Jose Joaquin de Olmedo
Mon 2/9
6:33 pm-8:41 pm
Nonstop2h 08m
Panama City Tocumen Intl
Sun 2/15
9:02 am-11:18 am
Nonstop2h 16m
Compare providers for flights from Guayaquil to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to Panama City in January.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guayaquil-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Guayaquil with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to Panama City
How far ahead should I book a flight from Guayaquil to Panama City?
The best time to book flights from Guayaquil to Panama City is 66 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Guayaquil to Panama City?
Currently, May is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $120). Flying from Guayaquil to Panama City in November is currently the most expensive (average of $188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from GYE to PTY?
A simple way to save on the total cost of your ticket is to fly from Guayaquil to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 24% on your trip compared to booking a flight at noon.
What is the cheapest day to fly from Guayaquil to Panama City?
Travelers seeking maximum savings on their Guayaquil to Panama City flight should consider departing on Friday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How often are flights from Guayaquil to Panama City delayed?
About 3% of weekly flights between Guayaquil and Panama City have experienced delays in the past year, with the average delay time being 101 minutes.
What is the most punctual flight time for Guayaquil to Panama City flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Guayaquil to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 3% of flights being delayed.
The best insider tips for Guayaquil to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Guayaquil to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 29, 2026.
Read through reviews of airlines operating flights from Guayaquil to Panama City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
Entertainment
Food
Boarding
Crew
Overall
Reviews
Juan,Dec 2025
EZE - PTY
Comfort
Entertainment
Food
Boarding
Crew
Overall
Reviews
Juan,Dec 2025
EZE - PTY
Comfort
Entertainment
Food
Boarding
Crew
Overall
Reviews
Juan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Guayaquil to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Guayaquil to Panama City
Discover the top 2 airlines that operate flights from Guayaquil to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$172 | Average$382 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$224 | Average$339 | FlexibilityNo cancel fee | On-time71% |