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Panama City

$172+ Cheap flights from Guayaquil (GYE) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — PTY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl are usually found in May or June, booked 67 days in advance, depart on a Friday or Saturday and return on a Saturday

Cheap flight deals from Guayaquil to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$339
(Avianca)

One-way from

$172
(FlightHub)

Popular in

October

Cheapest in

May

Average price

$346

Good round-trip deal

$379 or less

Good one-way deal

$297 or less
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Panama City Tocumen Intl flights.
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From Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl
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One-way flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl
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Highest demand for flights based on searches. 12% potential increase in price ($42 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl.
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Find flight deals from Guayaquil to Panama City

Cheapest flights from Guayaquil to Panama City
Explore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/183:30 amGYE - PTY
1 stop5h 20mAvianca
Thu 11/209:45 amPTY - GYE
1 stop4h 45mAvianca
Deal found 10/30$339
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/183:30 amGYE - PTY
1 stop5h 20mAvianca
Sat 11/225:50 pmPTY - GYE
1 stop5h 45mAvianca
Deal found 10/29$344
This Priceline deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/163:30 amGYE - PTY
1 stop5h 20mAvianca
Fri 11/212:55 amPTY - GYE
1 stop6h 20mAvianca
Deal found 10/29$347
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:30 amGYE - PTY
1 stop5h 20mAvianca
Sat 11/292:55 amPTY - GYE
1 stop6h 20mAvianca
Deal found 10/29$349
This FlightHub deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/273:30 amGYE - PTY
1 stop5h 20mAvianca
Sun 12/75:50 pmPTY - GYE
1 stop7h 15mAvianca
Deal found 10/30$351
This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1810:25 amGYE - PTY
1 stop6h 30mAvianca
Mon 11/242:55 amPTY - GYE
2 stops8h 30mAvianca
Deal found 10/30$359
This FlightHub deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/63:30 amGYE - PTY
1 stop13h 25mAvianca
Sat 11/82:55 amPTY - GYE
1 stop6h 20mAvianca
Deal found 10/29$363
This Priceline deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:55 pmGYE - PTY
1 stop5h 45mAvianca
Wed 12/32:55 amPTY - GYE
2 stops8h 30mAvianca
Deal found 10/29$367
This Priceline deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:30 amGYE - PTY
1 stop10h 30mAvianca
Sun 12/142:55 amPTY - GYE
1 stop11h 30mAvianca
Deal found 10/30$374
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/273:30 amGYE - PTY
1 stop10h 30mAvianca
Mon 12/12:55 amPTY - GYE
2 stops8h 30mAvianca
Deal found 10/29$379

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Guayaquil to Panama City that are best for you.

Fly from

Guayaquil

Fly to

Panama City

Route

Depart

Return

Price

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 1/7

12:20 pm-2:28 pm

Nonstop2h 08m

Panama City Tocumen Intl

Sat 1/10

11:17 am-1:34 pm

Nonstop2h 17m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 12/18

6:34 pm-8:41 pm

Nonstop2h 07m

Panama City Tocumen Intl

Tue 12/30

11:17 am-1:34 pm

Nonstop2h 17m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 12/22

4:32 am-6:41 am

Nonstop2h 09m

Panama City Tocumen Intl

Sat 12/27

9:02 am-11:18 am

Nonstop2h 16m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Tue 12/23

12:20 pm-2:32 pm

Nonstop2h 12m

Panama City Tocumen Intl

Sun 12/28

11:17 am-1:34 pm

Nonstop2h 17m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 12/17

4:32 am-6:41 am

Nonstop2h 09m

Panama City Tocumen Intl

Tue 12/23

9:02 am-11:18 am

Nonstop2h 16m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Sat 11/29

6:37 pm-8:43 pm

Nonstop2h 06m

Panama City Tocumen Intl

Mon 12/1

9:02 am-11:18 am

Nonstop2h 16m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 12/15

4:32 am-6:41 am

Nonstop2h 09m

Panama City Tocumen Intl

Sun 12/21

11:17 am-1:34 pm

Nonstop2h 17m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 1/8

4:33 am-6:41 am

Nonstop2h 08m

Panama City Tocumen Intl

Mon 1/12

6:27 pm-8:46 pm

Nonstop2h 19m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Sun 1/4

12:20 pm-2:28 pm

Nonstop2h 08m

Panama City Tocumen Intl

Thu 1/8

6:27 pm-8:46 pm

Nonstop2h 19m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 12/22

4:32 am-6:41 am

Nonstop2h 09m

Panama City Tocumen Intl

Fri 12/26

9:02 am-11:18 am

Nonstop2h 16m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 18 results
1
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Compare providers for flights from Guayaquil to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to Panama City in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Guayaquil-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Guayaquil-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Guayaquil-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guayaquil-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guayaquil to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to Panama City

How far ahead should I book a flight from Guayaquil to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to Panama City. Price data was last updated on October 24, 2025.

The best time to book flights from Guayaquil to Panama City is 67 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Guayaquil to Panama City?

Currently, May is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $120). Flying from Guayaquil to Panama City in September is currently the most expensive (average of $169). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to PTY?

Find hourly flight availability from Guayaquil to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Guayaquil to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 21% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Guayaquil to Panama City?

Use this chart to determine the cheapest time to fly round-trip from Guayaquil to Panama City. Price data was last updated on October 26, 2025.

Travelers seeking maximum savings on their Guayaquil to Panama City flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Guayaquil to Panama City?

The best insider tips for Guayaquil to Panama City flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Guayaquil to Panama City trip
Airlines
United Airlines

United’s Economy Plus provides extra legroom and priority boarding, enhancing comfort on international flights.


United’s Premium Plus offers upgraded comfort with bigger seats, extra legroom, and priority check-in.

Read more about United Airlinesby Harriet Baskas
Copa Airlines

Copa’s punctuality is impressive, ranking third globally with 89.46% on-time arrivals in 2023.


Copa’s Economy Classic offers one checked bag and advance seat selection, ideal for value-conscious travelers.

Read more about Copa Airlinesby Paul Rubio
Our travel experts
Harriet Baskas

Harriet Baskas

Expert on United Airlines

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more
Paul Rubio

Paul Rubio

Expert on Copa Airlines

Paul Rubio

Paul Rubio

Travel journalist and photographer Paul Rubio is a Miami native (and current resident), who has lived in nine countries and traveled to 137. He is an expert in luxury travel, eco-travel, loyalty programs, hotels, airports and airlines. He is a contributing editor at AFAR, Condé Nast Traveler, LUXURY Magazine, and Palm Beach Illustrated.

Read more

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Guayaquil to Panama City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Crew

8.1

Comfort

7.4

Overall

7.6

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,561 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Crew

8.1

Comfort

7.4

Overall

7.6

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.6
Okay
2,467 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Crew

8.1

Comfort

7.4

Overall

7.6

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Guayaquil to Panama City?

    You will need to book a flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl if you want to fly from Guayaquil to Panama City. At least 2 different airlines have flights from Jose Joaquin de Olmedo (GYE) to Tocumen Intl (PTY) on a regular basis. There are 6 flights to Panama City from the Guayaquil airport per day. If you manage to book one that is nonstop, then you can expect the flight time from GYE to PTY to be around 2h 06m.

  • How popular is this Guayaquil to Panama City flight route?

    This flight path from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl was viewed by 78 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Guayaquil to Panama City?

    There are many flights that can get you from Guayaquil to Panama City in 2h 08m. Fly via Copa Airlines to get the fastest option. There are 776 mi between Guayaquil and Panama City. All flights are typically nonstop.

  • What are the cheapest airlines flying from Guayaquil to Panama City round-trip?

    Our cheapest airline available from Guayaquil to Panama City is Copa Airlines. Our recent data shows that you can find tickets from as low as $222 on this airline. An additional option worth looking into is Avianca, starting at $230. Copa Airlines is currently priced 24% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Guayaquil to Panama City?

    No one likes to see their flight delayed. When booking a flight from Guayaquil to Panama City consider choosing Copa Airlines (92%), United Airlines (89%) or KLM (89%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Guayaquil to Panama City?

    Looking at all options, your cheapest flight can be booked for $229. While the most popular route (Guayaquil Jose Joaquin de Olmedo - Panama City Tocumen Intl) can be booked for $354 on average, our data indicates $744 when flying from Guayaquil to Panama City.

  • Can I find deals for flights from Guayaquil to Panama City that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Panama City.

  • Can I find deals for business class flights from Guayaquil to Panama City?

    Yes. Cheapflights offers flight deals from Guayaquil to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Panama City?

    Currently, May is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $120). Flying from Guayaquil to Panama City in September is currently the most expensive (average of $169). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Guayaquil to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Quito to Panama City flights

Top 2 airlines flying from Guayaquil to Panama City

Discover the top 2 airlines that operate flights from Guayaquil to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$222Average$369FlexibilityNo cancel feeOn-time70%
AviancaCheapest$230Average$328FlexibilityNo cancel feeOn-time71%

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