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Panama City

$163+ Cheap flights from Guayaquil (GYE) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — PTY
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl are usually found in May or June, booked 67 days in advance, depart on a Thursday or Wednesday and return on a Tuesday

Cheap flight deals from Guayaquil to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$333
(Gotogate)

One-way from

$163
(FlightHub)

Popular in

August

Cheapest in

May

Average price

$291

Good round-trip deal

$333 or less

Good one-way deal

$258 or less
From Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl
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One-way flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl
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Highest demand for flights based on searches. 4% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl.
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Find flight deals from Guayaquil to Panama City

Cheapest flights from Guayaquil to Panama City
Explore the most affordable flight options available from Guayaquil to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:55 pmGYE - PTY
1 stop5h 45mAvianca
Sun 12/143:19 amPTY - GYE
1 stop6h 31mAvianca
Deal found 7/29$332
This Copa Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/86:32 pmGYE - PTY
Nonstop2h 09mCopa Airlines
Fri 9/129:01 amPTY - GYE
Nonstop2h 14mCopa Airlines
Deal found 7/29$340
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2911:05 amGYE - PTY
1 stop5h 25mMultiple Airlines
Fri 9/56:20 pmPTY - GYE
Nonstop2h 14mMultiple Airlines
Deal found 7/30$373

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Guayaquil to Panama City that are best for you.

Fly from

Guayaquil

Fly to

Panama City

Route

Depart

Return

Price

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 11/26

6:55 pm-12:40 am

1 stop5h 45m

Panama City Tocumen Intl

Sun 12/14

3:19 am-9:50 am

1 stop6h 31m

$332

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 9/8

6:32 pm-8:41 pm

Nonstop2h 09m

Panama City Tocumen Intl

Fri 9/12

9:01 am-11:15 am

Nonstop2h 14m

$340

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Fri 8/29

11:05 am-4:30 pm

1 stop5h 25m

Panama City Tocumen Intl

Fri 9/5

6:20 pm-8:34 pm

Nonstop2h 14m

$373

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 9/1

3:35 am-8:55 am

1 stop5h 20m

$163

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 8/21

12:17 pm-2:27 pm

Nonstop2h 10m

$188

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 10/23

3:35 am-12:15 pm

2 stops8h 40m

$366

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 8/11

3:15 am-1:50 pm

2 stops34h 35m

$1,584

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

The best insider tips for Guayaquil to Panama City flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Guayaquil to Panama City trip
Airlines
United Airlines

United’s Economy Plus provides extra legroom and priority boarding, enhancing comfort on international flights.


United’s Premium Plus offers upgraded comfort with bigger seats, extra legroom, and priority check-in.

Read more about United Airlinesby Harriet Baskas
Copa Airlines

Copa’s punctuality is impressive, ranking third globally with 89.46% on-time arrivals in 2023.


Copa’s Economy Classic offers one checked bag and advance seat selection, ideal for value-conscious travelers.

Read more about Copa Airlinesby Paul Rubio
Our travel experts
Harriet Baskas

Harriet Baskas

Expert on United Airlines

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more
Paul Rubio

Paul Rubio

Expert on Copa Airlines

Paul Rubio

Paul Rubio

Travel journalist and photographer Paul Rubio is a Miami native (and current resident), who has lived in nine countries and traveled to 137. He is an expert in luxury travel, eco-travel, loyalty programs, hotels, airports and airlines. He is a contributing editor at AFAR, Condé Nast Traveler, LUXURY Magazine, and Palm Beach Illustrated.

Read more

Best time to book a flight from Guayaquil to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to Panama City

How far ahead should I book a flight from Guayaquil to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to Panama City. Price data was last updated on July 25, 2025.

The best time to book flights from Guayaquil to Panama City is 67 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Guayaquil to Panama City?

Currently, October is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $478). Flying from Guayaquil to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to PTY?

Find hourly flight availability from Guayaquil to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Guayaquil to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 27% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Guayaquil to Panama City?

Use this chart to determine the cheapest time to fly round-trip from Guayaquil to Panama City. Price data was last updated on July 27, 2025.

Travelers seeking maximum savings on their Guayaquil to Panama City flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Guayaquil to Panama City

Explore weekly flight availability from Guayaquil to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 30, 2025.

The most flights from GYE to PTY are scheduled on a Monday (15 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Guayaquil to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 30, 2025.
Read through reviews of airlines operating flights from Guayaquil to Panama City, such as Copa Airlines, United Airlines, and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,493 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.5

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

LIM - PTY

This was my first tome flying with this airline and needless to say, I was not impressed! The seats were not comfortable at all. You could feel the metal digging into your skin. Also, there was a kid behind me that kept putting his knees up on the seat and usually this doesn’t bother me, but I was able to feel his knees dig into my back every single time. The food was mediocore at best. There were no phone chargers on an almost 5 hour flight! Horrible experience. Will never fly with Copa airlines again!
Copa Airlines
7.5
Good
1,493 reviews
Copa Airlines
7.5
Good
1,493 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.5

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

LIM - PTY

This was my first tome flying with this airline and needless to say, I was not impressed! The seats were not comfortable at all. You could feel the metal digging into your skin. Also, there was a kid behind me that kept putting his knees up on the seat and usually this doesn’t bother me, but I was able to feel his knees dig into my back every single time. The food was mediocore at best. There were no phone chargers on an almost 5 hour flight! Horrible experience. Will never fly with Copa airlines again!
United Airlines
7.4
Good
8,896 reviews
Copa Airlines
7.5
Good
1,493 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.5

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

LIM - PTY

This was my first tome flying with this airline and needless to say, I was not impressed! The seats were not comfortable at all. You could feel the metal digging into your skin. Also, there was a kid behind me that kept putting his knees up on the seat and usually this doesn’t bother me, but I was able to feel his knees dig into my back every single time. The food was mediocore at best. There were no phone chargers on an almost 5 hour flight! Horrible experience. Will never fly with Copa airlines again!
Avianca
6.7
Okay
2,387 reviews
Copa Airlines
7.5
Good
1,493 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.5

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

LIM - PTY

This was my first tome flying with this airline and needless to say, I was not impressed! The seats were not comfortable at all. You could feel the metal digging into your skin. Also, there was a kid behind me that kept putting his knees up on the seat and usually this doesn’t bother me, but I was able to feel his knees dig into my back every single time. The food was mediocore at best. There were no phone chargers on an almost 5 hour flight! Horrible experience. Will never fly with Copa airlines again!

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Guayaquil to Panama City?

    You will need to book a flight from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl if you want to fly from Guayaquil to Panama City. At least 2 different airlines have flights from Jose Joaquin de Olmedo (GYE) to Tocumen Intl (PTY) on a regular basis. There are 8 flights to Panama City from the Guayaquil airport per day. If you manage to book one that is nonstop, then you can expect the flight time from GYE to PTY to be around 2h 06m.

  • How popular is this Guayaquil to Panama City flight route?

    This flight path from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl was viewed by 103 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Guayaquil to Panama City round-trip?

    Our cheapest airline available from Guayaquil to Panama City is Avianca. Our recent data shows that you can find tickets from as low as $333 on this airline. An additional option worth looking into is Copa Airlines, starting at $340.

  • What are the cheapest airlines to fly from Guayaquil to Panama City one-way?

    $163 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from $188 and $1,584, respectively.

  • What are the most reliable airlines from Guayaquil to Panama City?

    No one likes to see their flight delayed. When booking a flight from Guayaquil to Panama City consider choosing Copa Airlines (93%), Air France (90%) or Turkish Airlines (90%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Guayaquil to Panama City?

    Looking at all options, your cheapest flight can be booked for $181. While the most popular route (Guayaquil Jose Joaquin de Olmedo - Panama City Tocumen Intl) can be booked for $330 on average our data indicates $463 when flying from Guayaquil to Panama City.

  • Can I find deals for flights from Guayaquil to Panama City that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Panama City.

  • Can I find deals for business class flights from Guayaquil to Panama City?

    Yes. Cheapflights offers flight deals from Guayaquil to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Guayaquil to Panama City (average of $478). Flying from Guayaquil to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Guayaquil to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Quito to Panama City flights

Top 2 airlines flying from Guayaquil to Panama City

Discover the top 2 airlines that operate flights from Guayaquil to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$221Average$328FlexibilityNo cancel feeOn-time70%
AviancaCheapest$223Average$312FlexibilityNo cancel feeOn-time71%

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