HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$174+ Cheap flights from Columbus to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbus to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Columbus to Panama City Tocumen Intl are usually found in October or September, booked 16 days in advance, depart on a Wednesday or Monday and return on a Monday

Find flight deals from Columbus to Panama City

Cheapest flights from Columbus to Panama City
Explore the most affordable flight options available from Columbus to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:30 amCMH - PTY
1 stop10h 37mUnited Airlines
Sun 12/711:35 amPTY - CMH
1 stop10h 54mUnited Airlines
Deal found 10/12$431
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:25 pmCMH - PTY
2 stops20h 17mAmerican Airlines
Sun 12/74:43 pmPTY - CMH
2 stops19h 07mAmerican Airlines
Deal found 10/12$440
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:45 pmCMH - PTY
1 stop26h 53mUnited Airlines
Wed 11/264:41 pmPTY - CMH
2 stops16h 49mUnited Airlines
Deal found 10/12$445
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/264:45 pmCMH - PTY
1 stop26h 53mUnited Airlines
Wed 12/38:55 amPTY - CMH
1 stop13h 34mUnited Airlines
Deal found 10/12$467
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/268:17 pmCMH - PTY
2 stops17h 26mAmerican Airlines
Wed 12/34:43 pmPTY - CMH
2 stops17h 51mAmerican Airlines
Deal found 10/12$481
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/253:53 pmCMH - PTY
2 stops21h 50mAmerican Airlines
Tue 12/22:43 pmPTY - CMH
1 stop9h 46mAmerican Airlines
Deal found 10/10$517
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:32 pmCMH - PTY
2 stops20h 11mAmerican Airlines
Wed 11/262:43 pmPTY - CMH
2 stops19h 39mAmerican Airlines
Deal found 10/12$535
This Mytrip deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/33:08 pmCMH - PTY
3 stops25h 47mMultiple Airlines
Sun 12/72:55 pmPTY - CMH
3 stops31h 19mMultiple Airlines
Deal found 10/11$618
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1611:44 amCMH - PTY
1 stop7h 53mUnited Airlines
Sat 10/189:45 amPTY - CMH
1 stop11h 20mUnited Airlines
Deal found 10/12$632

Cheap flight deals from Columbus to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 13, 2025.

Round-trip from

$414
(Delta)

One-way from

$174
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$472
From Columbus to Panama City Tocumen Intl
Search Deals
One-way flight from Columbus to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from Columbus to Panama City that are best for you.

Fly from

Columbus

Fly to

Panama City

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 2/2

11:22 am-8:02 pm

1 stop8h 40m

Panama City Tocumen Intl

Tue 2/17

10:00 am-7:11 pm

1 stop9h 11m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 4/5

7:55 pm-12:55 pm

1 stop18h 00m

Panama City Tocumen Intl

Tue 4/7

2:20 pm-9:01 am

1 stop17h 41m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:07 pm-12:10 pm

1 stop19h 03m

Panama City Tocumen Intl

Tue 4/7

1:55 pm-12:07 pm

2 stops21h 12m

$428

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 12/3

6:30 am-5:07 pm

1 stop10h 37m

Panama City Tocumen Intl

Sun 12/7

8:55 am-10:29 pm

1 stop13h 34m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 12/3

7:25 pm-3:42 pm

2 stops20h 17m

Panama City Tocumen Intl

Sun 12/7

4:43 pm-11:50 am

2 stops19h 07m

$440

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sat 11/22

4:45 pm-7:38 pm

1 stop26h 53m

Panama City Tocumen Intl

Wed 11/26

4:41 pm-10:55 am

1 stop18h 14m

$440

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 1/29

6:30 am-2:45 pm

1 stop8h 15m

$174

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

8:25 pm-2:20 pm

2 stops18h 55m

$174

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:45 am-4:12 pm

1 stop10h 27m

$174

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sat 1/10

5:09 pm-1:27 pm

2 stops20h 18m

$191

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Showing 1-10 of 12 results
1
2

Best time to book a flight from Columbus to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Panama City

How far ahead should I book a flight from Columbus to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Columbus to Panama City. Price data was last updated on October 10, 2025.

The price you pay for your flight from Columbus to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 12 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Columbus to Panama City?

Currently, May is the cheapest month in which you can book a flight from Columbus to Panama City (average of $330). Flying from Columbus to Panama City in November is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PTY?

Find hourly flight availability from Columbus to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

It’s typically best to fly out from Columbus to Panama City in the evening. Doing so could potentially save you 36% on the flight price compared to flying at noon, which is usually more expensive.

How much does it cost to fly round-trip from Columbus to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 13, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Columbus to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,971 reviews

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,971 reviews
Delta
8.0
Very good
7,971 reviews

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,970 reviews
Delta
8.0
Very good
7,971 reviews

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,046 reviews
Delta
8.0
Very good
7,971 reviews

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Columbus?

    Panama City Tocumen Intl (PTY) is the airport you will fly into if you book a flight from Columbus to Panama City. You should not have trouble finding flights to Tocumen Intl from Columbus; the airport handles an average of 0 inbound flights from Columbus per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Panama City airport from Columbus. It is only a 11.4 mi journey from Tocumen Intl (PTY) to Panama City’s city center.

  • How long is the flight from Columbus to Panama City?

    Departing from Columbus to Panama City will take you 8h 40m. There are 2146 mi between Columbus and Panama City. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Columbus to Panama City round-trip?

    Currently priced at $393, Delta will fly you from Columbus to Panama City and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $430 and $450, respectively. Delta is 29% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Columbus to Panama City that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama City.

  • Can I find deals for business class flights from Columbus to Panama City?

    Yes. Cheapflights offers flight deals from Columbus to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Panama City?

    Currently, May is the cheapest month in which you can book a flight from Columbus to Panama City (average of $330). Flying from Columbus to Panama City in November is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Columbus to Panama City

Discover the top 3 airlines that operate flights from Columbus to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$571FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$430Average$545FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$450Average$575FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.