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$461+ Cheap flights from Istanbul (IST) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
IST — PTY
Sep 2 — Sep 91
Tue 9/2
Tue 9/9
1 adult, Economy
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Cheap flight deals from Istanbul to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Istanbul (IST) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 28, 2025.

Round-trip from

$957
(Air Europa)

One-way from

$461
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$1,295
From Istanbul to Panama City Tocumen Intl
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One-way flight from Istanbul to Panama City Tocumen Intl
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Highest demand for flights based on searches. 3% potential increase in price ($50 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Istanbul to Panama City

Cheapest flights from Istanbul to Panama City
Explore the most affordable flight options available from Istanbul to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2025.

This Air Europa deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:15 pmIST - PTY
1 stop34h 30mAir Europa
Thu 12/119:30 pmPTY - IST
1 stop33h 25mAir Europa
Deal found 8/28$957
This Air Europa deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:45 pmIST - PTY
1 stop34h 55mAir Europa
Wed 10/158:25 pmPTY - IST
1 stop33h 30mAir Europa
Deal found 8/28$958
This Air Europa deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:15 pmIST - PTY
1 stop34h 30mAir Europa
Thu 12/119:30 pmPTY - IST
1 stop33h 25mAir Europa
Deal found 8/28$987
This KLM deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/145:05 pmIST - PTY
1 stop31h 45mMultiple Airlines
Mon 9/297:55 pmPTY - IST
1 stop23h 30mMultiple Airlines
Deal found 8/26$1,005
This KLM deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:05 pmIST - PTY
1 stop31h 45mMultiple Airlines
Sun 10/127:55 pmPTY - IST
1 stop23h 30mMultiple Airlines
Deal found 8/26$1,013
This Air Europa deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:45 pmIST - PTY
1 stop34h 55mAir Europa
Sun 10/58:25 pmPTY - IST
1 stop33h 30mAir Europa
Deal found 8/27$1,018
This SmartFares deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/233:45 pmIST - PTY
1 stop34h 55mAir Europa
Wed 10/18:25 pmPTY - IST
1 stop33h 30mAir Europa
Deal found 8/27$1,028
This KLM deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/96:10 amIST - PTY
1 stop18h 40mKLM
Sun 10/126:50 pmPTY - IST
2 stops24h 35mKLM
Deal found 8/26$1,032
This KLM deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:20 amIST - PTY
1 stop21h 25mMultiple Airlines
Wed 10/16:50 pmPTY - IST
2 stops24h 35mMultiple Airlines
Deal found 8/27$1,039
This KLM deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:20 amIST - PTY
1 stop21h 25mMultiple Airlines
Sat 10/46:50 pmPTY - IST
2 stops24h 35mMultiple Airlines
Deal found 8/28$1,051
This KLM deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/104:20 amIST - PTY
2 stops20h 30mKLM
Mon 10/136:50 pmPTY - IST
2 stops24h 35mKLM
Deal found 8/26$1,052
This KLM deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:10 amIST - PTY
2 stops19h 35mKLM
Wed 10/16:50 pmPTY - IST
2 stops24h 35mKLM
Deal found 8/27$1,059

Cheapflights Fare Finder

 
Customize your flight search to find flights from Istanbul to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Istanbul Airport to Panama City that are best for you.

Fly from

Istanbul

Fly to

Panama City

Route

Depart

Return

Price

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Thu 11/6

5:15 pm-7:45 pm

1 stop34h 30m

Panama City Tocumen Intl

Thu 12/11

9:30 pm-2:55 pm

1 stop33h 25m

$957

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Wed 11/5

5:15 pm-7:45 pm

1 stop34h 30m

Panama City Tocumen Intl

Thu 12/11

9:30 pm-2:55 pm

1 stop33h 25m

$957

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Fri 11/7

5:15 pm-7:45 pm

1 stop34h 30m

Panama City Tocumen Intl

Thu 12/11

9:30 pm-2:55 pm

1 stop33h 25m

$957

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Mon 11/10

5:15 pm-7:45 pm

1 stop34h 30m

Panama City Tocumen Intl

Thu 12/11

9:30 pm-2:55 pm

1 stop33h 25m

$957

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Tue 10/7

3:45 pm-6:40 pm

1 stop34h 55m

Panama City Tocumen Intl

Wed 10/15

8:25 pm-1:55 pm

1 stop33h 30m

$958

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Sun 11/9

5:15 pm-7:45 pm

1 stop34h 30m

Panama City Tocumen Intl

Thu 12/11

9:30 pm-2:55 pm

1 stop33h 25m

$987

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Sun 9/14

5:05 pm-4:50 pm

1 stop31h 45m

Panama City Tocumen Intl

Mon 9/29

7:55 pm-3:25 am

1 stop23h 30m

$1,005

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Thu 9/11

5:05 pm-4:50 pm

1 stop31h 45m

Panama City Tocumen Intl

Mon 10/13

7:55 pm-3:25 am

1 stop23h 30m

$1,013

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Wed 9/10

5:05 pm-4:50 pm

1 stop31h 45m

Panama City Tocumen Intl

Mon 10/13

7:55 pm-3:25 am

1 stop23h 30m

$1,013

IstanbulPanama City

IST - PTY

ISTPTY

Istanbul

Thu 9/11

6:10 am-4:50 pm

1 stop18h 40m

Panama City Tocumen Intl

Sun 10/12

7:55 pm-3:25 am

1 stop23h 30m

$1,013

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/27

Showing 1-10 of 17 results
1
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Best time to book a flight from Istanbul to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Istanbul with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Istanbul Airport to Panama City

What is the cheapest month to book a flight from Istanbul Airport to Panama City?

Currently, October is the cheapest month in which you can book a flight from Istanbul Airport to Panama City (average of $478). Flying from Istanbul Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IST to PTY?

Find hourly flight availability from Istanbul to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 28, 2025.

It’s typically best to fly out from Istanbul Airport to Panama City in the morning. Doing so could potentially save you 32% on the flight price compared to flying at noon, which is usually more expensive.

How much does it cost to fly round-trip from Istanbul Airport to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 28, 2025.
Read through reviews of airlines operating flights from Istanbul Airport to Panama City, such as Turkish Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Turkish Airlines
7.3
Good
3,954 reviews

Boarding

7.3

Comfort

7.3

Crew

7.7

Food

7.4

Entertainment

7.4

Overall

7.3

Reviews

1 / 20
4.0
Okay

Leslie,Feb 2025

IST - LAX

Food and staff were nice but difficulty with WIFI, console sound not working. X-cover insurance a scam. Denying purchase of insurance even with proof. Ridiculous.
Turkish Airlines
7.3
Good
3,954 reviews
Turkish Airlines
7.3
Good
3,954 reviews

Boarding

7.3

Comfort

7.3

Crew

7.7

Food

7.4

Entertainment

7.4

Overall

7.3

Reviews

1 / 20
4.0
Okay

Leslie,Feb 2025

IST - LAX

Food and staff were nice but difficulty with WIFI, console sound not working. X-cover insurance a scam. Denying purchase of insurance even with proof. Ridiculous.

Related info for your journey

Find useful and relevant information for your journey from Istanbul to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Istanbul?

    If you book a flight to Panama City from Istanbul, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 2 flights from Istanbul to Tocumen Intl per day from 1 airline.

  • How long is the flight from Istanbul Airport to Panama City?

    For as low as $957, Air Europa can have you in Panama City from Istanbul Airport in 34h 30m. The distance between Istanbul Airport and Panama City is about 6717 mi.

  • What is the cheapest airline to fly from Istanbul Airport to Panama City round-trip?

    Cheapflights users have booked flights from Istanbul Airport to Panama City round-trip from $1,319.

  • Can I find deals for flights from Istanbul to Panama City that include hotel bookings?

    Yes. In addition to deals on Istanbul to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Istanbul to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Istanbul to Panama City.

  • Can I find deals for business class flights from Istanbul to Panama City?

    Yes. Cheapflights offers flight deals from Istanbul to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Istanbul Airport to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Istanbul Airport to Panama City (average of $478). Flying from Istanbul Airport to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Istanbul to Panama City

Discover the top airline that operate flights from Istanbul to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$1,319Average$1,502FlexibilityNo cancel feeOn-time77%

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