$171+ Cheap flights from Buffalo (BUF) to Panama City Beach, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PNS
Mar 9 — Mar 161
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Buffalo to Panama City BeachExplore the most affordable flight options available from Buffalo to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.
Explore the most affordable flight options available from Buffalo to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:01 am
BUF
- ECP
1 stop7h 09m
Delta
Mon 3/96:43 pm
ECP
- BUF
1 stop4h 03m
Delta
Deal found 2/6![Delta logo]()
$341
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:23 am
BUF
- ECP
2 stops10h 24m
Delta
Wed 3/185:30 pm
ECP
- BUF
2 stops15h 12m
Delta
Deal found 2/5![Delta logo]()
$345
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:28 pm
BUF
- ECP
1 stop5h 18m
American Airlines
Mon 5/47:21 am
ECP
- BUF
1 stop4h 44m
American Airlines
Deal found 2/6![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:30 pm
BUF
- ECP
1 stop23h 44m
Delta
Sat 5/165:30 pm
ECP
- BUF
1 stop5h 29m
Delta
Deal found 2/5![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:28 pm
BUF
- ECP
1 stop5h 18m
American Airlines
Sat 5/23:38 pm
ECP
- BUF
1 stop4h 56m
American Airlines
Deal found 2/6![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:40 pm
BUF
- ECP
1 stop5h 09m
American Airlines
Thu 4/97:21 am
ECP
- BUF
2 stops8h 14m
American Airlines
Deal found 2/6![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:25 pm
BUF
- ECP
2 stops8h 24m
American Airlines
Mon 3/91:20 pm
ECP
- BUF
2 stops8h 30m
American Airlines
Deal found 2/6![American Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:00 pm
BUF
- ECP
1 stop4h 50m
Southwest
Sun 5/175:35 am
ECP
- BUF
2 stops7h 40m
Southwest
Deal found 2/4![Southwest logo]()
$379
Best flights from Buffalo to Panama City BeachDiscover carefully curated flight deals from Buffalo to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 7, 2026.
Discover carefully curated flight deals from Buffalo to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 7, 2026.
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:23 am
BUF
- ECP
2 stops10h 24m
Delta
Wed 3/185:30 pm
ECP
- BUF
2 stops15h 12m
Delta
Deal found 2/5![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:00 pm
BUF
- ECP
1 stop4h 50m
Southwest
Sun 5/175:35 am
ECP
- BUF
2 stops7h 40m
Southwest
Deal found 2/4![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:00 am
BUF
- ECP
1 stop7h 14m
United Airlines
Tue 3/102:10 pm
ECP
- BUF
1 stop5h 36m
United Airlines
Deal found 2/5![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:30 pm
BUF
- ECP
1 stop23h 44m
Delta
Mon 5/186:47 pm
ECP
- BUF
1 stop4h 12m
Delta
Deal found 2/5![Delta logo]()
$361
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:20 pm
BUF
- ECP
1 stop5h 50m
Southwest
Tue 3/101:20 pm
ECP
- BUF
1 stop4h 00m
Southwest
Deal found 2/5![Southwest logo]()
$397
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:10 pm
BUF
- ECP
1 stop4h 54m
Delta
Mon 5/186:47 pm
ECP
- BUF
1 stop4h 12m
Delta
Deal found 2/5![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:32 pm
BUF
- ECP
1 stop4h 56m
Delta
Sat 5/165:30 pm
ECP
- BUF
1 stop5h 29m
Delta
Deal found 2/5![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:10 pm
BUF
- ECP
1 stop6h 50m
Delta
Sat 5/166:00 am
ECP
- BUF
2 stops8h 12m
Delta
Deal found 2/5![Delta logo]()
$392
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:04 am
BUF
- ECP
2 stops7h 46m
Delta
Mon 5/186:47 pm
ECP
- BUF
1 stop4h 12m
Delta
Deal found 2/5![Delta logo]()
$392
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:01 am
BUF
- ECP
1 stop7h 09m
Delta
Mon 3/96:00 am
ECP
- BUF
1 stop4h 01m
Delta
Deal found 2/3![Delta logo]()
$397
Last-minute flights from Buffalo to Panama City BeachDiscover last-minute flight deals from Buffalo to Panama City Beach. Data last updated February 7, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Panama City Beach. Data last updated February 7, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:01 am
BUF
- ECP
1 stop7h 09m
Delta
Mon 3/96:43 pm
ECP
- BUF
1 stop4h 03m
Delta
Deal found 2/6![Delta logo]()
$341
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:25 pm
BUF
- ECP
2 stops8h 24m
American Airlines
Mon 3/91:20 pm
ECP
- BUF
2 stops8h 30m
American Airlines
Deal found 2/6![American Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:25 pm
BUF
- ECP
2 stops7h 45m
Southwest
Sat 3/145:00 pm
ECP
- BUF
1 stop5h 55m
Southwest
Deal found 2/5![Southwest logo]()
$428
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:23 am
BUF
- ECP
2 stops10h 24m
Delta
Wed 3/185:30 pm
ECP
- BUF
2 stops15h 12m
Delta
Deal found 2/5![Delta logo]()
$345
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:40 pm
BUF
- ECP
1 stop5h 09m
American Airlines
Wed 3/184:34 pm
ECP
- BUF
1 stop6h 16m
American Airlines
Deal found 2/5![American Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:40 pm
BUF
- ECP
1 stop5h 09m
American Airlines
Mon 3/164:34 pm
ECP
- BUF
1 stop6h 16m
American Airlines
Deal found 2/5![American Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:02 am
BUF
- ECP
2 stops10h 34m
Delta
Mon 3/236:43 pm
ECP
- BUF
1 stop4h 03m
Delta
Deal found 2/5![Delta logo]()
$392
One-way flights from Buffalo to Panama City BeachSearch for one-way flight options from Buffalo to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated February 7, 2026.
Search for one-way flight options from Buffalo to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated February 7, 2026.
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:00 am
BUF
- ECP
1 stop7h 14m
United Airlines
Deal found 2/6![United Airlines logo]()
$171
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:15 am
BUF
- ECP
2 stops10h 21m
Delta
Deal found 2/6![Delta logo]()
$176
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:35 pm
BUF
- ECP
1 stop19h 09m
American Airlines
Deal found 2/6![American Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:19 am
BUF
- ECP
1 stop4h 47m
American Airlines
Deal found 2/4![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/47:45 pm
BUF
- ECP
2 stops14h 53m
United Airlines
Deal found 2/4![United Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/151:05 pm
BUF
- ECP
1 stop6h 40m
Southwest
Deal found 2/6![Southwest logo]()
$379
Find flight deals from Buffalo to Panama City Beach
Keep the following information in mind while searching for Buffalo to Panama City Beach flight deals. Data was last updated February 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $341 (Delta) |
One-way from | $171 (American Airlines) |
Popular in | April |
Cheapest in | November |
Average price | $407 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Panama City Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City Beach that are best for you.
Fly from
Buffalo
Fly to
Panama City Beach
Route
Depart
Return
Price
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Wed 3/11
10:23 am-7:47 pm
2 stops10h 24m
Panama City NW Florida Beaches
Wed 3/18
5:30 pm-9:42 am
2 stops15h 12m
$345
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Sat 5/9
1:30 pm-12:14 pm
1 stop23h 44m
Panama City NW Florida Beaches
Mon 5/18
6:47 pm-11:59 pm
1 stop4h 12m
$361
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Sat 5/9
2:00 pm-5:50 pm
1 stop4h 50m
Panama City NW Florida Beaches
Sun 5/17
5:35 am-2:15 pm
2 stops7h 40m
$379
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Sun 5/10
12:10 pm-4:04 pm
1 stop4h 54m
Panama City NW Florida Beaches
Mon 5/18
6:47 pm-11:59 pm
1 stop4h 12m
$387
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Fri 5/8
7:32 pm-11:28 pm
1 stop4h 56m
Panama City NW Florida Beaches
Sat 5/16
5:30 pm-11:59 pm
1 stop5h 29m
$387
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Sun 5/10
12:10 pm-6:00 pm
1 stop6h 50m
Panama City NW Florida Beaches
Sat 5/16
6:00 am-3:12 pm
2 stops8h 12m
$392
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Fri 5/8
6:04 am-12:50 pm
2 stops7h 46m
Panama City NW Florida Beaches
Mon 5/18
6:47 pm-11:59 pm
1 stop4h 12m
$392
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Thu 3/5
7:00 am-1:14 pm
1 stop7h 14m
Panama City NW Florida Beaches
Tue 3/10
2:10 pm-8:46 pm
1 stop5h 36m
$397
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Tue 3/3
1:20 pm-6:10 pm
1 stop5h 50m
Panama City NW Florida Beaches
Tue 3/10
1:20 pm-6:20 pm
1 stop4h 00m
$397
BuffaloPanama City
BUF - ECP
BUFECP
Buffalo
Mon 3/2
6:01 am-12:10 pm
1 stop7h 09m
Panama City NW Florida Beaches
Mon 3/9
6:00 am-11:01 am
1 stop4h 01m
$397
Showing 1-10 of 17 results
Best time to book a flight from Buffalo to Panama City Beach
Have a flexible travel schedule? Discover the best time to fly to Panama City Beach from Buffalo with our price prediction graph.
BUF-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Panama City Beach
BUF-PA9
BUF-ECP
What is the cheapest month to book a flight from Buffalo to Panama City Beach?
Currently, December is the cheapest month in which you can book a flight from Buffalo to Panama City Beach (average of $82). Flying from Buffalo to Panama City Beach in July is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Panama City Beach
Get insights into the airlines that provide service to Panama City Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City Beach. Reviews last updated February 7, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Buffalo to Panama City Beach to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Panama City Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Panama City Beach by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Buffalo to Panama City Beach, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and Panama City Beach flights
Browse other Buffalo and Panama City Beach flight options. Last updated on February 7, 2026.
Other flights from Buffalo
Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on February 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Buffalo to Panama City Beach flights
Consider these flights traveling from Buffalo to Panama City Beach.
Top 3 airlines flying from Buffalo to Panama City Beach
Discover the top 3 airlines that operate flights from Buffalo to Panama City Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$199 | Average$412 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$457 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$295 | Average$542 | FlexibilityNo cancel fee | On-time63% |