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$92+ Cheap flights from Knoxville (TYS) to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CVG
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Knoxville to Ohio

Keep the following information in mind while searching for Knoxville to Ohio flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$180
(Booking.com)

One-way from

$92
(American Airlines)

Popular in

December

Cheapest in

June

Average price

$275
From Knoxville McGhee Tyson to Ohio
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One-way flight from Knoxville McGhee Tyson to Ohio
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Highest demand for flights based on searches. 6% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to Ohio

Cheapest flights from Knoxville to Ohio
Explore the most affordable flight options available from Knoxville to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Booking.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/67:17 pmTYS - CVG
1 stop25h 03mFrontier
dom. 11/96:05 amCVG - TYS
1 stop12h 17mFrontier
Deal found 9/11$180
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/87:00 amTYS - CLE
1 stop5h 31mAmerican Airlines
mié. 10/155:25 amCLE - TYS
1 stop7h 31mAmerican Airlines
Deal found 9/10$183
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/88:09 amTYS - CMH
1 stop5h 38mAmerican Airlines
mié. 10/156:50 amCMH - TYS
1 stop6h 06mAmerican Airlines
Deal found 9/9$183
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/261:06 pmTYS - PIT
1 stop4h 45mAmerican Airlines
mar. 9/3010:24 amPIT - TYS
1 stop6h 25mAmerican Airlines
Deal found 9/11$221
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/305:45 amTYS - CMH
1 stop4h 54mDelta
mié. 10/16:00 amCMH - TYS
1 stop3h 44mDelta
Deal found 9/10$228
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/255:55 pmTYS - CMH
1 stop17h 46mMultiple Airlines
vie. 10/312:31 pmCMH - TYS
1 stop11h 05mMultiple Airlines
Deal found 9/10$230
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/245:59 pmTYS - PIT
2 stops20h 23mMultiple Airlines
lun. 10/276:51 pmPIT - TYS
1 stop15h 42mMultiple Airlines
Deal found 9/11$232
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/255:55 pmTYS - CMH
1 stop17h 46mMultiple Airlines
sáb. 9/275:15 amCMH - TYS
1 stop10h 26mMultiple Airlines
Deal found 9/10$233
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/266:24 pmTYS - DTW
2 stops20h 22mMultiple Airlines
mar. 9/307:10 pmDTW - TYS
1 stop16h 45mMultiple Airlines
Deal found 9/10$234
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/244:31 pmTYS - PIT
2 stops27h 25mMultiple Airlines
dom. 9/287:00 amPIT - TYS
1 stop11h 45mMultiple Airlines
Deal found 9/8$236
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/148:26 amTYS - CMH
1 stop6h 56mUnited Airlines
mar. 11/1810:30 amCMH - TYS
1 stop4h 13mUnited Airlines
Deal found 9/10$236
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/75:44 amTYS - CMH
1 stop5h 29mDelta
mar. 10/1410:02 amCMH - TYS
1 stop3h 40mDelta
Deal found 9/9$239

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Knoxville to Ohio that are best for you.

Fly from

Knoxville

Fly to

Ohio

Route

Depart

Return

Price

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

jue. 11/6

7:17 pm-8:20 pm

1 stop25h 03m

Cincinnati Cinci./N. Kentucky

dom. 11/9

6:05 am-6:22 pm

1 stop12h 17m

$180

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

mié. 10/8

7:00 am-12:31 pm

1 stop5h 31m

Cleveland Hopkins Intl

mié. 10/15

5:25 am-12:56 pm

1 stop7h 31m

$183

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

mié. 10/8

8:09 am-1:47 pm

1 stop5h 38m

Columbus

mié. 10/15

6:50 am-12:56 pm

1 stop6h 06m

$183

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

vie. 9/26

1:06 pm-5:51 pm

1 stop4h 45m

Pittsburgh

mar. 9/30

10:24 am-4:49 pm

1 stop6h 25m

$221

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

mar. 9/30

5:45 am-10:39 am

1 stop4h 54m

Columbus

mié. 10/1

6:00 am-9:44 am

1 stop3h 44m

$228

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

jue. 9/25

5:55 pm-11:41 am

1 stop17h 46m

Columbus

vie. 10/3

12:31 pm-11:36 pm

1 stop11h 05m

$230

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

vie. 10/24

5:59 pm-2:22 pm

2 stops20h 23m

Pittsburgh

lun. 10/27

6:51 pm-10:33 am

1 stop15h 42m

$232

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

jue. 9/25

5:55 pm-11:41 am

1 stop17h 46m

Columbus

sáb. 9/27

5:15 am-3:41 pm

1 stop10h 26m

$233

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

vie. 9/26

6:24 pm-2:46 pm

2 stops20h 22m

Detroit Metropolitan Wayne County

mar. 9/30

7:10 pm-11:55 am

1 stop16h 45m

$234

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

dom. 11/2

5:45 am-12:09 pm

1 stop6h 24m

Pittsburgh

mié. 11/5

4:01 pm-10:55 pm

1 stop6h 54m

$236

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 60 results
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Best time to book a flight from Knoxville to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Ohio

What is the cheapest month to book a flight from Knoxville to Ohio?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $239). Flying from Knoxville to Ohio in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to OH?

Find hourly flight availability from Knoxville to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Knoxville to Ohio, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated septiembre 11, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Ohio have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Ohio?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Ohio. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Ohio?

    Departing from Knoxville to Ohio will take you 4h 54m. Airlines will cover a distance of 296 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Knoxville to Ohio one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $92. Delta flights start at $99 while deals on Frontier start at $99 one-way.

  • What are the most popular routes from Knoxville to Ohio?

    The most popular flight routes from Knoxville to Ohio are Knoxville McGhee Tyson - Detroit Metropolitan Wayne County, Knoxville McGhee Tyson - Columbus and Knoxville McGhee Tyson - Pittsburgh.

  • Can I find deals for flights from Knoxville to Ohio that include hotel bookings?

    Yes. In addition to deals on Knoxville to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Ohio.

  • Can I find deals for business class flights from Knoxville to Ohio?

    Yes. Cheapflights offers flight deals from Knoxville to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Ohio?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $239). Flying from Knoxville to Ohio in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Ohio

Discover the top 3 airlines that operate flights from Knoxville to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$213Average$444FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$213Average$291FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$302FlexibilityNo cancel feeOn-timeN/A

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