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$92+ Cheap flights from Knoxville (TYS) to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CVG
Apr 11 — Apr 181
Sa 4/11
Sa 4/18
1 adult, Economy
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Cheap flight deals from Knoxville to Ohio

Cheapest flights from Knoxville to Ohio
Explore the most affordable flight options available from Knoxville to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on März 12, 2026.

This Frontier deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/164:28 pm
TYS
-
CLE
1 stop8h 29m
Frontier
Sa 4/255:21 pm
CLE
-
TYS
1 stop22h 12m
Frontier
Deal found 3/7$161
This CheapOair deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 4/104:20 pm
TYS
-
DTW
1 stop18h 38m
Frontier
So 4/1211:54 am
DTW
-
TYS
1 stop27h 34m
Frontier
Deal found 3/10$212
This Expedia deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 5/118:32 pm
TYS
-
CLE
1 stop14h 25m
Frontier
Mo 5/1812:08 pm
CLE
-
TYS
1 stop7h 25m
Frontier
Deal found 3/11$222
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/84:25 pm
TYS
-
DTW
1 stop8h 14m
Multiple Airlines
Mi 4/151:37 pm
DTW
-
TYS
1 stop25h 08m
Multiple Airlines
Deal found 3/11$242
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/304:31 pm
TYS
-
CLE
1 stop15h 08m
Multiple Airlines
Fr 5/16:32 pm
CLE
-
TYS
1 stop18h 37m
Multiple Airlines
Deal found 3/10$255
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 3/277:15 am
TYS
-
DTW
1 stop8h 35m
Multiple Airlines
Di 3/315:12 pm
DTW
-
TYS
2 stops25h 06m
Multiple Airlines
Deal found 3/9$259
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/72:56 pm
TYS
-
DTW
2 stops17h 06m
Multiple Airlines
Di 4/141:37 pm
DTW
-
TYS
1 stop20h 59m
Multiple Airlines
Deal found 3/9$262
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/2312:37 pm
TYS
-
PIT
1 stop10h 47m
Allegiant Air
So 4/267:00 am
PIT
-
TYS
1 stop13h 27m
Allegiant Air
Deal found 3/10$262
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/84:25 pm
TYS
-
CLE
2 stops18h 21m
Multiple Airlines
Mi 4/157:38 pm
CLE
-
TYS
1 stop25h 04m
Multiple Airlines
Deal found 3/7$262
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/149:40 pm
TYS
-
CVG
2 stops20h 56m
Multiple Airlines
Mo 5/257:56 pm
CVG
-
TYS
1 stop17h 36m
Multiple Airlines
Deal found 3/7$262
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/225:50 pm
TYS
-
DTW
1 stop3h 45m
Southwest
Mi 4/294:10 pm
DTW
-
TYS
1 stop3h 30m
Southwest
Deal found 3/10$263
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/243:00 pm
TYS
-
CLE
1 stop8h 28m
Multiple Airlines
Mo 3/306:45 pm
CLE
-
TYS
1 stop19h 25m
Multiple Airlines
Deal found 3/10$263

Find flight deals from Knoxville to Ohio

Keep the following information in mind while searching for Knoxville to Ohio flight deals. Data was last updated März 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$161
(Frontier)

One-way from

$92
(CheapOair)

Popular in

October

Cheapest in

June

Average price

$271
Provider with most accurate pricing for Knoxville McGhee Tyson-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Cleveland Hopkins Intl flights.
Search Deals
From Knoxville McGhee Tyson to Ohio
Search Deals
One-way flight from Knoxville McGhee Tyson to Ohio
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($105 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 12, 2026.
Use the filters below to find and compare flights from Knoxville to Ohio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Mi 4/8

4:25 pm-10:46 am

2 stops18h 21m

Cleveland Hopkins Intl

Mi 4/15

7:38 pm-8:42 pm

1 stop25h 04m

$262

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Mi 4/22

8:15 am-9:15 pm

2 stops13h 00m

Detroit Metropolitan Wayne County

Mi 4/29

12:40 pm-8:50 pm

2 stops8h 10m

$273

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Mi 4/8

7:00 am-1:19 pm

1 stop6h 19m

Cleveland Hopkins Intl

Mi 4/8

6:00 pm-11:08 pm

1 stop5h 08m

$279

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Mi 4/8

7:05 am-12:45 pm

1 stop5h 40m

Cleveland Hopkins Intl

Mi 4/15

4:20 pm-8:50 pm

1 stop4h 30m

$279

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Mi 4/8

5:53 pm-11:59 pm

1 stop6h 06m

Cleveland Hopkins Intl

Mi 4/15

12:25 pm-5:01 pm

1 stop4h 36m

$279

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Do 4/16

6:35 am-3:05 pm

2 stops8h 30m

Cleveland Hopkins Intl

Sa 4/25

6:05 am-11:40 am

1 stop5h 35m

$284

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Mi 4/8

5:53 pm-11:53 pm

1 stop6h 00m

Pittsburgh

Do 4/9

10:30 am-3:09 pm

1 stop4h 39m

$286

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

Do 4/16

6:00 am-10:25 am

1 stop4h 25m

Cincinnati Cinci./N. Kentucky

Mi 4/22

7:53 pm-11:55 pm

1 stop4h 02m

$287

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

Do 4/16

7:20 pm-11:59 pm

1 stop4h 39m

Cincinnati Cinci./N. Kentucky

Mi 4/22

6:15 pm-11:08 pm

1 stop4h 53m

$287

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Di 4/7

7:05 am-12:30 pm

1 stop5h 25m

Columbus

Do 4/9

1:15 pm-8:20 pm

2 stops7h 05m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Ohio

What is the cheapest month to book a flight from Knoxville to Ohio?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $171). Flying from Knoxville to Ohio in November is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated März 12, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Ohio have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,285 reviews

Comfort

7.9

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,285 reviews
Delta
7.9
Good
8,285 reviews

Comfort

7.9

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,418 reviews
Delta
7.9
Good
8,285 reviews

Comfort

7.9

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,446 reviews
Delta
7.9
Good
8,285 reviews

Comfort

7.9

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Ohio?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Ohio. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Ohio?

    Departing from Knoxville to Ohio will take you 5h 40m. Airlines will cover a distance of 404 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Knoxville to Ohio one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $99. United Airlines flights start at $131 while deals on Delta start at $133 one-way.

  • What are the most popular routes from Knoxville to Ohio?

    The most popular flight routes from Knoxville to Ohio are Knoxville McGhee Tyson - Cleveland Hopkins Intl, Knoxville McGhee Tyson - Detroit Metropolitan Wayne County and Knoxville McGhee Tyson - Pittsburgh.

  • Can I find deals for flights from Knoxville to Ohio that include hotel bookings?

    Yes. In addition to deals on Knoxville to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Ohio.

  • Can I find deals for business class flights from Knoxville to Ohio?

    Yes. Cheapflights offers flight deals from Knoxville to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Ohio?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $171). Flying from Knoxville to Ohio in November is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Ohio

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Top 3 airlines flying from Knoxville to Ohio

Discover the top 3 airlines that operate flights from Knoxville to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$373FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$213Average$315FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$360FlexibilityNo cancel feeOn-timeN/A

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