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$114+ Cheap flights from Knoxville (TYS) to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CVG
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Knoxville to Ohio

Cheapest flights from Knoxville to Ohio
Explore the most affordable flight options available from Knoxville to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:13 pmTYS - CLE
1 stop13h 30mMultiple Airlines
Tue 12/2311:43 amCLE - TYS
2 stops23h 28mMultiple Airlines
Deal found 12/9$253
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:30 amTYS - CAK
1 stop26h 50mAllegiant Air
Mon 12/226:37 pmCAK - TYS
1 stop26h 34mAllegiant Air
Deal found 12/11$286
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:42 amTYS - PIT
1 stop4h 08mAmerican Airlines
Mon 12/292:12 pmPIT - TYS
1 stop7h 17mAmerican Airlines
Deal found 12/10$330
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:35 pmTYS - CLE
1 stop6h 03mUnited Airlines
Mon 12/297:49 pmCLE - TYS
1 stop4h 10mUnited Airlines
Deal found 12/10$337
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:00 amTYS - CAK
1 stop6h 08mUnited Airlines
Sat 12/205:44 pmCAK - TYS
1 stop4h 55mUnited Airlines
Deal found 12/11$355
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:52 pmTYS - CLE
1 stop18h 15mMultiple Airlines
Tue 12/164:48 pmCLE - TYS
1 stop17h 54mMultiple Airlines
Deal found 12/10$357
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:39 amTYS - DTW
Nonstop1h 50mDelta
Fri 1/26:52 pmDTW - TYS
Nonstop1h 40mDelta
Deal found 12/10$359
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:30 amTYS - CAK
1 stop26h 50mMultiple Airlines
Mon 12/221:03 pmCAK - TYS
2 stops19h 15mMultiple Airlines
Deal found 12/11$363
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:42 amTYS - CMH
1 stop6h 27mAmerican Airlines
Sun 1/46:35 amCMH - TYS
1 stop4h 15mAmerican Airlines
Deal found 12/10$377
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:39 amTYS - DTW
Nonstop1h 50mDelta
Fri 1/27:00 amDTW - TYS
1 stop4h 58mDelta
Deal found 12/11$379
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:59 pmTYS - CMH
1 stop5h 14mDelta
Sat 1/172:16 pmCMH - TYS
1 stop5h 08mDelta
Deal found 12/10$379
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:45 amTYS - CMH
1 stop6h 45mUnited Airlines
Mon 12/297:45 pmCMH - TYS
1 stop4h 14mUnited Airlines
Deal found 12/9$386

Find flight deals from Knoxville to Ohio

Keep the following information in mind while searching for Knoxville to Ohio flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$195
(Kiwi.com)

One-way from

$114
(Kiwi.com)

Popular in

October

Cheapest in

June

Average price

$454
Provider with most accurate pricing for Knoxville McGhee Tyson-Cleveland Hopkins Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Cleveland Hopkins Intl flights.
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From Knoxville McGhee Tyson to Ohio
Search Deals
One-way flight from Knoxville McGhee Tyson to Ohio
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($124 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Knoxville to Ohio that are best for you.

Fly from

Knoxville

Fly to

Ohio

Route

Depart

Return

Price

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Wed 1/21

4:47 pm-11:44 pm

1 stop6h 57m

Pittsburgh

Tue 1/27

5:50 pm-3:57 pm

1 stop22h 07m

$195

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Sat 1/17

11:59 am-11:44 pm

1 stop11h 45m

Pittsburgh

Sun 1/18

11:00 am-11:05 pm

1 stop12h 05m

$208

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Wed 1/14

4:47 pm-5:04 pm

1 stop24h 17m

Detroit Metropolitan Wayne County

Tue 2/3

6:36 pm-3:57 pm

1 stop21h 21m

$227

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 1/8

1:39 pm-10:20 am

2 stops44h 41m

Detroit Metropolitan Wayne County

Thu 1/15

1:18 pm-5:28 pm

1 stop28h 10m

$245

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Thu 1/8

9:29 am-11:10 pm

1 stop13h 41m

Cleveland Hopkins Intl

Fri 1/9

7:01 pm-11:09 am

1 stop16h 08m

$249

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Sat 1/24

5:40 am-12:08 pm

1 stop6h 28m

Pittsburgh

Sat 1/31

4:59 pm-11:45 pm

1 stop6h 46m

$251

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 2/24

1:00 pm-5:13 pm

1 stop4h 13m

Columbus

Wed 2/25

6:00 am-11:08 am

1 stop5h 08m

$251

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

Mon 1/26

12:55 pm-3:03 pm

1 stop26h 08m

Cincinnati Cinci./N. Kentucky

Mon 2/2

2:43 pm-10:21 pm

1 stop7h 38m

$251

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 1/9

12:55 pm-11:41 pm

1 stop10h 46m

Detroit Metropolitan Wayne County

Sun 1/11

5:15 pm-5:28 pm

1 stop24h 13m

$262

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 1/16

7:20 pm-11:44 pm

1 stop4h 24m

Columbus

Sun 1/18

6:00 am-10:57 am

1 stop4h 57m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 54 results
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Best time to book a flight from Knoxville to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Ohio

What is the cheapest month to book a flight from Knoxville to Ohio?

Currently, December is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $154). Flying from Knoxville to Ohio in November is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to OH?

Find hourly flight availability from Knoxville to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s typically best to fly out from Knoxville to Ohio at noon. Doing so could potentially save you 26% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Ohio have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Ohio?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Ohio. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Ohio?

    Departing from Knoxville to Ohio will take you 4h 13m. Airlines will cover a distance of 296 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Knoxville to Ohio one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $99. Delta flights start at $133 while deals on United Airlines start at $191 one-way.

  • What are the most popular routes from Knoxville to Ohio?

    The most popular flight routes from Knoxville to Ohio are Knoxville McGhee Tyson - Detroit Metropolitan Wayne County, Knoxville McGhee Tyson - Columbus and Knoxville McGhee Tyson - Pittsburgh.

  • Can I find deals for flights from Knoxville to Ohio that include hotel bookings?

    Yes. In addition to deals on Knoxville to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Ohio.

  • Can I find deals for business class flights from Knoxville to Ohio?

    Yes. Cheapflights offers flight deals from Knoxville to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Ohio?

    Currently, December is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $154). Flying from Knoxville to Ohio in November is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Ohio

Discover the top 3 airlines that operate flights from Knoxville to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$444FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$213Average$290FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$333FlexibilityNo cancel feeOn-timeN/A

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