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$92+ Cheap flights from Knoxville (TYS) to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CVG
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Knoxville to Ohio

Cheapest flights from Knoxville to Ohio
Explore the most affordable flight options available from Knoxville to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:56 pm
TYS
-
CLE
2 stops29h 15m
Multiple Airlines
Sun 3/16:29 pm
CLE
-
TYS
1 stop24h 02m
Multiple Airlines
Deal found 1/24$214
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/232:06 pm
TYS
-
CLE
2 stops29h 08m
Multiple Airlines
Mon 3/29:06 am
CLE
-
TYS
1 stop9h 25m
Multiple Airlines
Deal found 1/24$241
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:20 am
TYS
-
DTW
2 stops24h 47m
Multiple Airlines
Mon 3/95:09 am
DTW
-
TYS
1 stop6h 51m
Multiple Airlines
Deal found 1/25$251
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/217:38 am
TYS
-
CMH
1 stop5h 54m
Delta
Sat 2/286:00 am
CMH
-
TYS
1 stop5h 08m
Delta
Deal found 1/26$251
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/101:00 pm
TYS
-
CVG
1 stop25h 41m
Multiple Airlines
Sat 2/147:05 pm
CVG
-
TYS
2 stops27h 20m
Multiple Airlines
Deal found 1/26$264
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/129:32 pm
TYS
-
DTW
1 stop22h 08m
Multiple Airlines
Thu 2/1910:10 am
DTW
-
TYS
2 stops12h 00m
Multiple Airlines
Deal found 1/25$266
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/31:00 pm
TYS
-
CLE
1 stop11h 43m
Multiple Airlines
Wed 2/47:02 pm
CLE
-
TYS
1 stop23h 26m
Multiple Airlines
Deal found 1/26$266
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:05 am
TYS
-
CLE
1 stop5h 35m
Southwest
Wed 4/84:20 pm
CLE
-
TYS
1 stop4h 30m
Southwest
Deal found 1/26$267
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:30 am
TYS
-
DTW
2 stops31h 00m
Multiple Airlines
Sun 3/110:59 pm
DTW
-
TYS
1 stop13h 01m
Multiple Airlines
Deal found 1/25$268
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:54 am
TYS
-
PIT
1 stop6h 51m
Multiple Airlines
Sun 3/89:09 pm
PIT
-
TYS
1 stop13h 52m
Multiple Airlines
Deal found 1/26$269
This Southwest deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:50 pm
TYS
-
CLE
1 stop3h 45m
Southwest
Thu 5/1410:55 am
CLE
-
TYS
1 stop7h 15m
Southwest
Deal found 1/24$274
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:15 am
TYS
-
DTW
1 stop24h 34m
Multiple Airlines
Mon 2/235:09 am
DTW
-
TYS
1 stop6h 51m
Multiple Airlines
Deal found 1/25$275

Find flight deals from Knoxville to Ohio

Keep the following information in mind while searching for Knoxville to Ohio flight deals. Data was last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$251
(Kiwi.com)

One-way from

$92
(CheapOair)

Popular in

October

Cheapest in

June

Average price

$288
Provider with most accurate pricing for Knoxville McGhee Tyson-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Cleveland Hopkins Intl flights.
Search Deals
From Knoxville McGhee Tyson to Ohio
Search Deals
One-way flight from Knoxville McGhee Tyson to Ohio
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($124 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Knoxville to Ohio that are best for you.

Fly from

Knoxville

Fly to

Ohio

Route

Depart

Return

Price

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Sun 2/22

5:56 pm-11:11 pm

2 stops29h 15m

Cleveland Hopkins Intl

Sun 3/1

6:29 pm-6:31 pm

1 stop24h 02m

$214

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Mon 2/23

2:06 pm-7:14 pm

2 stops29h 08m

Cleveland Hopkins Intl

Mon 3/2

9:06 am-6:31 pm

1 stop9h 25m

$241

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 2/21

7:38 am-1:32 pm

1 stop5h 54m

Columbus

Sat 2/28

6:00 am-11:08 am

1 stop5h 08m

$251

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 3/5

7:20 am-8:07 am

2 stops24h 47m

Detroit Metropolitan Wayne County

Mon 3/9

5:09 am-12:00 pm

1 stop6h 51m

$251

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

Tue 2/10

1:00 pm-2:41 pm

1 stop25h 41m

Cincinnati Cinci./N. Kentucky

Sat 2/14

7:05 pm-10:25 pm

2 stops27h 20m

$264

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Tue 4/7

8:15 am-12:10 pm

1 stop3h 55m

Cleveland Hopkins Intl

Wed 4/8

4:20 pm-8:50 pm

1 stop4h 30m

$267

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 2/12

9:32 pm-7:40 pm

1 stop22h 08m

Detroit Metropolitan Wayne County

Thu 2/19

10:59 pm-12:00 pm

1 stop13h 01m

$273

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Wed 5/6

5:50 pm-9:35 pm

1 stop3h 45m

Cleveland Hopkins Intl

Thu 5/14

10:55 am-6:10 pm

1 stop7h 15m

$274

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Mon 2/16

7:15 am-12:09 am

1 stop16h 54m

Detroit Metropolitan Wayne County

Thu 2/19

10:10 am-10:10 pm

2 stops12h 00m

$277

KnoxvilleAkron

TYS - CAK

TYSCAK

Knoxville McGhee Tyson

Thu 2/5

2:57 pm-9:18 pm

1 stop6h 21m

Akron/Canton

Mon 2/9

6:28 am-12:46 pm

1 stop6h 18m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 60 results
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Best time to book a flight from Knoxville to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Ohio

What is the cheapest month to book a flight from Knoxville to Ohio?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $171). Flying from Knoxville to Ohio in November is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated January 26, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Ohio have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,111 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,199 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,189 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Ohio?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Ohio. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Ohio?

    Departing from Knoxville to Ohio will take you 3h 55m. Airlines will cover a distance of 404 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Knoxville to Ohio one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $99. Delta flights start at $133 while deals on United Airlines start at $191 one-way.

  • What are the most popular routes from Knoxville to Ohio?

    The most popular flight routes from Knoxville to Ohio are Knoxville McGhee Tyson - Detroit Metropolitan Wayne County, Knoxville McGhee Tyson - Pittsburgh and Knoxville McGhee Tyson - Cleveland Hopkins Intl.

  • Can I find deals for flights from Knoxville to Ohio that include hotel bookings?

    Yes. In addition to deals on Knoxville to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Ohio.

  • Can I find deals for business class flights from Knoxville to Ohio?

    Yes. Cheapflights offers flight deals from Knoxville to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Ohio?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $171). Flying from Knoxville to Ohio in November is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Ohio

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Ohio

Discover the top 3 airlines that operate flights from Knoxville to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$355FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$213Average$282FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$344FlexibilityNo cancel feeOn-timeN/A

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