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$77+ Cheap flights from Knoxville (TYS) to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CVG
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheap flight deals from Knoxville to Ohio

Keep the following information in mind while searching for Knoxville to Ohio flight deals. Data was last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$198
(Kiwi.com)

One-way from

$77
(Kiwi.com)

Popular in

October

Cheapest in

June

Average price

$568
Provider with most accurate pricing for Knoxville McGhee Tyson-Cleveland Hopkins Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Cleveland Hopkins Intl flights.
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From Knoxville McGhee Tyson to Ohio
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One-way flight from Knoxville McGhee Tyson to Ohio
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Highest demand for flights based on searches. 24% potential increase in price ($102 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Knoxville to Ohio

Cheapest flights from Knoxville to Ohio
Explore the most affordable flight options available from Knoxville to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:22 pmTYS - PIT
1 stop25h 28mAllegiant Air
Sun 12/142:18 pmPIT - TYS
1 stop8h 24mAllegiant Air
Deal found 10/27$198
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:30 amTYS - DTW
1 stop10h 30mMultiple Airlines
Mon 11/176:10 amDTW - TYS
1 stop7h 47mMultiple Airlines
Deal found 10/28$203
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:32 pmTYS - PIT
1 stop18h 37mMultiple Airlines
Sun 11/167:00 amPIT - TYS
1 stop5h 26mMultiple Airlines
Deal found 10/28$217
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:30 amTYS - DTW
1 stop6h 33mMultiple Airlines
Tue 11/187:17 pmDTW - TYS
1 stop17h 40mMultiple Airlines
Deal found 10/27$218
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:22 pmTYS - PIT
1 stop25h 28mAllegiant Air
Sun 12/72:18 pmPIT - TYS
1 stop8h 24mAllegiant Air
Deal found 10/26$225
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:54 amTYS - CLE
1 stop14h 05mMultiple Airlines
Sat 11/154:45 pmCLE - TYS
1 stop16h 19mMultiple Airlines
Deal found 10/28$228
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:43 pmTYS - PIT
1 stop11h 58mMultiple Airlines
Mon 12/87:10 amPIT - TYS
1 stop14h 39mMultiple Airlines
Deal found 10/26$230
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/179:09 pmTYS - DTW
1 stop14h 47mMultiple Airlines
Wed 11/199:00 pmDTW - TYS
1 stop14h 34mMultiple Airlines
Deal found 10/28$232
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:32 pmTYS - DTW
2 stops19h 31mMultiple Airlines
Sun 11/168:00 pmDTW - TYS
1 stop17h 57mMultiple Airlines
Deal found 10/28$234
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:38 pmTYS - CLE
2 stops14h 44mMultiple Airlines
Mon 11/1711:14 amCLE - TYS
1 stop12h 00mMultiple Airlines
Deal found 10/27$236
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/94:52 pmTYS - DTW
1 stop21h 03mMultiple Airlines
Sat 12/137:42 pmDTW - TYS
1 stop26h 02mMultiple Airlines
Deal found 10/28$238
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/179:29 pmTYS - CLE
1 stop24h 06mMultiple Airlines
Mon 12/17:51 pmCLE - TYS
2 stops45h 21mMultiple Airlines
Deal found 10/26$238

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Knoxville to Ohio that are best for you.

Fly from

Knoxville

Fly to

Ohio

Route

Depart

Return

Price

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 11/15

7:30 am-6:00 pm

1 stop10h 30m

Detroit Metropolitan Wayne County

Mon 11/17

6:10 am-1:57 pm

1 stop7h 47m

$203

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Wed 11/12

4:32 pm-11:09 am

1 stop18h 37m

Pittsburgh

Sun 11/16

7:00 am-12:26 pm

1 stop5h 26m

$217

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 11/11

7:30 am-2:03 pm

1 stop6h 33m

Detroit Metropolitan Wayne County

Tue 11/18

7:17 pm-12:57 pm

1 stop17h 40m

$218

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Thu 12/4

1:22 pm-2:50 pm

1 stop25h 28m

Pittsburgh

Sun 12/7

2:18 pm-10:42 pm

1 stop8h 24m

$225

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Thu 11/13

9:54 am-11:59 pm

1 stop14h 05m

Cleveland Hopkins Intl

Sat 11/15

4:45 pm-9:04 am

1 stop16h 19m

$228

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Thu 12/4

12:43 pm-12:41 am

1 stop11h 58m

Pittsburgh

Mon 12/8

7:10 am-9:49 pm

1 stop14h 39m

$230

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Fri 11/14

9:38 pm-12:22 pm

2 stops14h 44m

Cleveland Hopkins Intl

Mon 11/17

11:14 am-11:14 pm

1 stop12h 00m

$236

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Mon 11/17

9:29 pm-9:35 pm

1 stop24h 06m

Cleveland Hopkins Intl

Mon 12/1

7:51 pm-5:12 pm

2 stops45h 21m

$238

KnoxvilleAkron

TYS - CAK

TYSCAK

Knoxville McGhee Tyson

Tue 11/11

6:16 pm-10:56 pm

1 stop4h 40m

Akron/Canton

Sat 11/15

6:28 pm-10:54 pm

1 stop4h 26m

$239

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 12/25

7:00 am-1:00 pm

1 stop6h 00m

Columbus

Wed 12/31

8:23 am-12:52 pm

1 stop4h 29m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 60 results
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Best time to book a flight from Knoxville to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Ohio

What is the cheapest month to book a flight from Knoxville to Ohio?

Currently, December is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $170). Flying from Knoxville to Ohio in October is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to OH?

Find hourly flight availability from Knoxville to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

It’s typically best to fly out from Knoxville to Ohio at noon. Doing so could potentially save you 26% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated October 28, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Ohio have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
9,001 reviews
Delta
7.9
Good
7,994 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Ohio?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Ohio. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Ohio?

    Departing from Knoxville to Ohio will take you 4h 40m. Airlines will cover a distance of 379 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Knoxville to Ohio one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $87. Allegiant Air flights start at $114 while deals on Delta start at $126 one-way.

  • What are the most popular routes from Knoxville to Ohio?

    The most popular flight routes from Knoxville to Ohio are Knoxville McGhee Tyson - Detroit Metropolitan Wayne County, Knoxville McGhee Tyson - Pittsburgh and Knoxville McGhee Tyson - Akron/Canton.

  • Can I find deals for flights from Knoxville to Ohio that include hotel bookings?

    Yes. In addition to deals on Knoxville to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Ohio.

  • Can I find deals for business class flights from Knoxville to Ohio?

    Yes. Cheapflights offers flight deals from Knoxville to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Ohio?

    Currently, December is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $170). Flying from Knoxville to Ohio in October is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Ohio

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Ohio

Discover the top 3 airlines that operate flights from Knoxville to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$213Average$444FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$213Average$290FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$303FlexibilityNo cancel feeOn-timeN/A

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