HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$850+ Cheap flights from Spain to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
May 31 — Jun 71
Sun 5/31
Sun 6/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Spain to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Spain to Panama City

Cheapest flights from Spain to Panama City
Explore the most affordable flight options available from Spain to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.

This KLM deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:05 pm
MAD
-
ECP
2 stops16h 46m
KLM
Sun 8/3011:15 am
ECP
-
MAD
1 stop18h 00m
KLM
Deal found 4/29$850
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:55 am
MAD
-
ECP
2 stops34h 49m
United Airlines
Wed 6/172:05 pm
ECP
-
MAD
2 stops33h 45m
United Airlines
Deal found 4/26$875
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:55 am
MAD
-
ECP
2 stops21h 06m
United Airlines
Mon 6/12:05 pm
ECP
-
MAD
2 stops35h 00m
United Airlines
Deal found 4/27$895
This Kissandfly.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:05 pm
MAD
-
ECP
2 stops27h 39m
Lufthansa
Wed 6/1710:25 am
ECP
-
MAD
2 stops16h 25m
Lufthansa
Deal found 4/26$912
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
MAD
-
ECP
2 stops24h 28m
Delta
Mon 6/16:45 pm
ECP
-
MAD
1 stop10h 30m
Delta
Deal found 4/27$1,005
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/109:50 am
MAD
-
ECP
1 stop29h 24m
Delta
Wed 6/176:00 am
ECP
-
MAD
2 stops20h 55m
Delta
Deal found 4/26$1,010
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/103:55 pm
MAD
-
ECP
1 stop26h 57m
American Airlines
Wed 6/171:15 pm
ECP
-
MAD
1 stop13h 20m
American Airlines
Deal found 4/26$1,038
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:05 pm
MAD
-
ECP
2 stops26h 09m
Delta
Sat 8/296:00 am
ECP
-
MAD
2 stops20h 55m
Delta
Deal found 4/29$1,055

Find flight deals from Spain to Panama City

Keep the following information in mind while searching for Spain to Panama City flight deals. Data was last updated May 1, 2026.

Round-trip from

$850
(KLM)
From Spain to Panama City NW Florida Beaches
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spain to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Spain to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 6/3

1:05 pm-10:51 pm

2 stops16h 46m

Panama City NW Florida Beaches

Sun 8/30

11:15 am-12:15 pm

1 stop18h 00m

$850

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 5/25

5:55 am-8:01 pm

2 stops21h 06m

Panama City NW Florida Beaches

Mon 6/1

2:05 pm-8:05 am

2 stops35h 00m

$895

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 5/25

6:00 am-11:28 pm

2 stops24h 28m

Panama City NW Florida Beaches

Mon 6/1

6:45 pm-12:15 pm

1 stop10h 30m

$1,005

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 6/10

9:50 am-8:14 am

1 stop29h 24m

Panama City NW Florida Beaches

Wed 6/17

6:00 am-9:55 am

2 stops20h 55m

$1,010

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 6/10

3:55 pm-11:52 am

1 stop26h 57m

Panama City NW Florida Beaches

Wed 6/17

1:15 pm-9:35 am

1 stop13h 20m

$1,038

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/30

1:05 pm-8:14 am

2 stops26h 09m

Panama City NW Florida Beaches

Sat 8/29

4:10 pm-7:15 pm

2 stops20h 05m

$1,051

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 6/10

6:20 am-8:01 pm

3 stops20h 41m

Panama City NW Florida Beaches

Wed 6/17

10:25 am-9:50 am

2 stops16h 25m

$1,070
Cheapest one-way

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sat 5/16

12:20 pm-10:03 am

2 stops28h 43m

$1,045

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 5/13

11:45 am-12:36 pm

1 stop31h 51m

$1,137
Quickest one-way

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 5/18

7:35 pm-11:35 am

2 stops23h 00m

$1,137

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Spain to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Spain with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spain to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Spain to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Spain?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Spain to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Spain to Panama City, Florida?

    There are many flights that can get you from Spain to Panama City, Florida in 16h 46m. Fly via KLM, United Airlines, or Delta to get the fastest option. The distance between Spain and Panama City, Florida is about 4513 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Spain to Panama City that include hotel bookings?

    Yes. In addition to deals on Spain to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spain to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spain to Panama City.

  • Can I find deals for business class flights from Spain to Panama City?

    Yes. Cheapflights offers flight deals from Spain to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.