Panama City

$908+ Cheap flights from Spain to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
Jul 18 — Jul 251
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Cheap flight deals from Spain to Panama City

Cheapest flights from Spain to Panama City
Explore the most affordable flight options available from Spain to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.

This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:20 am
MAD
-
ECP
2 stops36h 32m
United Airlines
Mon 9/211:54 pm
ECP
-
MAD
2 stops36h 06m
United Airlines
Deal found 6/17$908
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:30 pm
MAD
-
ECP
2 stops18h 06m
American Airlines
Mon 9/211:32 pm
ECP
-
MAD
1 stop13h 03m
American Airlines
Deal found 6/17$1,017
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:50 am
MAD
-
ECP
2 stops29h 54m
United Airlines
Sat 8/296:30 am
ECP
-
MAD
2 stops42h 35m
United Airlines
Deal found 6/14$1,047
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:55 pm
MAD
-
ECP
1 stop26h 59m
American Airlines
Tue 7/711:00 am
ECP
-
MAD
1 stop11h 30m
American Airlines
Deal found 6/17$1,053
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:25 am
MAD
-
ECP
2 stops28h 49m
Delta
Tue 7/75:03 pm
ECP
-
MAD
2 stops16h 42m
Delta
Deal found 6/17$1,060

Find flight deals from Spain to Panama City

Keep the following information in mind while searching for Spain to Panama City flight deals. Data was last updated June 18, 2026.

Round-trip from

$908
(United Airlines)
From Spain to Panama City NW Florida Beaches

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spain to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Spain to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 9/17

8:20 am-1:52 pm

2 stops36h 32m

Panama City NW Florida Beaches

Mon 9/21

1:54 pm-9:00 am

2 stops36h 06m

$908

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 9/17

12:30 pm-11:36 pm

2 stops18h 06m

Panama City NW Florida Beaches

Mon 9/21

1:32 pm-9:35 am

1 stop13h 03m

$1,019

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/30

10:50 am-9:44 am

2 stops29h 54m

Panama City NW Florida Beaches

Sat 8/29

6:30 am-8:05 am

2 stops42h 35m

$1,049

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 7/3

3:55 pm-11:54 am

1 stop26h 59m

Panama City NW Florida Beaches

Tue 7/7

11:00 am-5:30 am

1 stop11h 30m

$1,053

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 7/3

10:25 am-8:14 am

2 stops28h 49m

Panama City NW Florida Beaches

Tue 7/7

5:03 pm-4:45 pm

2 stops16h 42m

$1,060
Quickest round-trip

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/30

12:45 pm-9:59 pm

2 stops16h 14m

Panama City NW Florida Beaches

Sat 8/29

5:02 pm-12:15 pm

1 stop12h 13m

$1,155

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/17

Sorted by cheapest first

Best time to book a flight from Spain to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Spain with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spain to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Spain to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from Spain?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Spain to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Spain to Panama City, Florida?

    There are many flights that can get you from Spain to Panama City, Florida in 18h 06m. Fly via United Airlines or American Airlines to get the fastest option. The distance between Spain and Panama City, Florida is about 4513 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Spain to Panama City that include hotel bookings?

    Yes. In addition to deals on Spain to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spain to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spain to Panama City.

  • Can I find deals for business class flights from Spain to Panama City?

    Yes. Cheapflights offers flight deals from Spain to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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