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Panama City

$249+ Cheap flights from Roanoke to Panama City, FL (ROA - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — ECP
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$249
(Delta)

Popular in

May

Cheapest in

November

Average price

$333
From Roanoke to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Roanoke to Panama City

Cheapest flights from Roanoke to Panama City
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:00 amROA - ECP
1 stop5h 53mDelta
Tue 12/96:00 amECP - ROA
1 stop3h 40mDelta
Deal found 9/15$249
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:12 amROA - ECP
2 stops9h 35mAmerican Airlines
Wed 12/105:50 pmECP - ROA
1 stop4h 06mAmerican Airlines
Deal found 9/15$254
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:20 amROA - ECP
1 stop5h 18mAmerican Airlines
Mon 12/155:50 pmECP - ROA
1 stop4h 06mAmerican Airlines
Deal found 9/15$266
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:45 amROA - ECP
1 stop7h 25mUnited Airlines
Mon 10/61:55 pmECP - ROA
1 stop6h 46mUnited Airlines
Deal found 9/14$343
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/28:04 amROA - ECP
2 stops10h 11mAmerican Airlines
Tue 12/98:30 amECP - ROA
1 stop5h 36mAmerican Airlines
Deal found 9/15$390
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:20 amROA - ECP
2 stops12h 29mUnited Airlines
Tue 12/96:30 amECP - ROA
2 stops11h 26mUnited Airlines
Deal found 9/15$467
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:00 pmROA - ECP
1 stop3h 58mDelta
Sat 12/276:59 pmECP - ROA
1 stop4h 06mDelta
Deal found 9/14$498
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:00 amROA - ECP
2 stops7h 31mAmerican Airlines
Wed 9/246:06 pmECP - ROA
1 stop4h 02mAmerican Airlines
Deal found 9/14$710

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Roanoke

Fly to

Panama City

Route

Depart

Return

Price

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 12/2

7:00 am-11:53 am

1 stop5h 53m

Panama City NW Florida Beaches

Tue 12/9

6:00 am-10:40 am

1 stop3h 40m

$249

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 12/3

8:00 pm-10:38 pm

1 stop3h 38m

Panama City NW Florida Beaches

Wed 12/10

6:00 am-10:40 am

1 stop3h 40m

$249

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 12/3

8:12 am-4:47 pm

2 stops9h 35m

Panama City NW Florida Beaches

Wed 12/10

5:50 pm-10:56 pm

1 stop4h 06m

$254

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 12/10

7:20 am-11:38 am

1 stop5h 18m

Panama City NW Florida Beaches

Mon 12/15

5:50 pm-10:56 pm

1 stop4h 06m

$266

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 3/3

6:00 am-8:20 am

1 stop3h 20m

Panama City NW Florida Beaches

Sat 3/7

7:45 am-2:39 pm

1 stop5h 54m

$300

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Fri 10/3

6:45 am-1:10 pm

1 stop7h 25m

Panama City NW Florida Beaches

Mon 10/6

1:55 pm-9:41 pm

1 stop6h 46m

$343

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 12/2

8:04 am-5:15 pm

2 stops10h 11m

Panama City NW Florida Beaches

Tue 12/9

8:30 am-3:06 pm

1 stop5h 36m

$390

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 12/2

10:20 am-9:49 pm

2 stops12h 29m

Panama City NW Florida Beaches

Tue 12/9

6:30 am-6:56 pm

2 stops11h 26m

$467

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 9/23

6:00 am-8:08 am

1 stop3h 08m

$337

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 9/24

7:51 pm-11:03 pm

1 stop4h 12m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 11 results
1
2

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama City

What is the cheapest month to book a flight from Roanoke to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Roanoke to Panama City, Florida (average of $346). Flying from Roanoke to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to ECP?

Find hourly flight availability from Roanoke to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 25% on flights from Roanoke to Panama City, Florida by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 16, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Roanoke to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City, Florida?

    Airlines like Delta and American Airlines fly from Roanoke to Panama City, Florida in about 5h 53m. The time it takes to get you to your destination can typically vary by up to 3h 42m. The distance from Roanoke to Panama City, Florida is about 585 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Roanoke to Panama City, Florida round-trip?

    Flying on Delta is currently your cheapest option to Panama City, Florida, with prices starting at $248. Another option worth looking into is American Airlines, starting at $248 round trip. These flights start at 25% lower than the current average price 3 months from now.

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Roanoke to Panama City, Florida (average of $346). Flying from Roanoke to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top 2 airlines flying from Roanoke to Panama City

Discover the top 2 airlines that operate flights from Roanoke to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$334FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$308FlexibilityNo cancel feeOn-time71%

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