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Panama City

$239+ Cheap flights from Roanoke to Panama City, FL (ROA - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — ECP
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from Roanoke to Panama City

Best flights from Roanoke to Panama City
Discover carefully curated flight deals from Roanoke to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 3, 2025.

This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/96:47 pmROA - ECP
1 stop5h 08mDelta
Mon 1/126:00 amECP - ROA
1 stop3h 44mDelta
Deal found 11/2$249
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/91:56 pmROA - ECP
1 stop4h 37mAmerican Airlines
Mon 1/1212:03 pmECP - ROA
2 stops7h 13mAmerican Airlines
Deal found 11/2$368
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/910:15 amROA - ECP
2 stops12h 44mUnited Airlines
Mon 1/126:30 amECP - ROA
2 stops12h 32mUnited Airlines
Deal found 11/2$453
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:27 pmROA - ECP
1 stop3h 58mAmerican Airlines
Sat 3/77:19 amECP - ROA
2 stops9h 17mAmerican Airlines
Deal found 11/1$369
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 amROA - ECP
1 stop3h 41mDelta
Sat 3/75:14 pmECP - ROA
1 stop5h 35mDelta
Deal found 11/2$384
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 amROA - ECP
1 stop3h 17mDelta
Fri 5/17:05 pmECP - ROA
1 stop3h 44mDelta
Deal found 11/1$477
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:24 amROA - ECP
2 stops6h 14mAmerican Airlines
Thu 3/122:58 pmECP - ROA
1 stop3h 18mAmerican Airlines
Deal found 11/2$482
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:00 amROA - ECP
2 stops10h 06mUnited Airlines
Fri 5/13:10 pmECP - ROA
2 stops21h 48mUnited Airlines
Deal found 11/1$542
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:00 amROA - ECP
1 stop5h 17mDelta
Thu 3/127:45 amECP - ROA
1 stop5h 54mDelta
Deal found 11/2$477
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:45 amROA - ECP
2 stops10h 26mUnited Airlines
Sat 3/74:55 pmECP - ROA
2 stops14h 39mUnited Airlines
Deal found 11/1$618

Cheap flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$239
(Delta)

Popular in

May

Cheapest in

February

Average price

$258
Provider with most accurate pricing for Roanoke-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Panama City NW Florida Beaches flights.
Search Deals
From Roanoke to Panama City NW Florida Beaches
Search Deals
One-way flight from Roanoke to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Roanoke

Fly to

Panama City

Route

Depart

Return

Price

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Fri 1/9

6:47 pm-10:55 pm

1 stop5h 08m

Panama City NW Florida Beaches

Mon 1/12

6:00 am-10:44 am

1 stop3h 44m

$249

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Fri 1/9

1:56 pm-5:33 pm

1 stop4h 37m

Panama City NW Florida Beaches

Mon 1/12

12:03 pm-8:16 pm

2 stops7h 13m

$368

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 3/3

7:27 pm-10:25 pm

1 stop3h 58m

Panama City NW Florida Beaches

Sat 3/7

7:19 am-5:36 pm

2 stops9h 17m

$369

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 3/3

6:00 am-8:41 am

1 stop3h 41m

Panama City NW Florida Beaches

Sat 3/7

5:14 pm-11:49 pm

1 stop5h 35m

$384

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Fri 1/9

10:15 am-9:59 pm

2 stops12h 44m

Panama City NW Florida Beaches

Mon 1/12

6:30 am-8:02 pm

2 stops12h 32m

$453

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 4/29

6:00 am-8:17 am

1 stop3h 17m

Panama City NW Florida Beaches

Fri 5/1

7:05 pm-11:49 pm

1 stop3h 44m

$477

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Mon 3/9

6:00 am-10:17 am

1 stop5h 17m

Panama City NW Florida Beaches

Thu 3/12

7:45 am-2:39 pm

1 stop5h 54m

$477

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Mon 3/9

8:24 am-1:38 pm

2 stops6h 14m

Panama City NW Florida Beaches

Thu 3/12

2:58 pm-7:16 pm

1 stop3h 18m

$482

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 4/29

11:00 am-8:06 pm

2 stops10h 06m

Panama City NW Florida Beaches

Fri 5/1

3:10 pm-1:58 pm

2 stops21h 48m

$542

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 3/3

6:45 am-4:11 pm

2 stops10h 26m

Panama City NW Florida Beaches

Sat 3/7

4:55 pm-8:34 am

2 stops14h 39m

$618

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 14 results
1
2

Compare providers for flights from Roanoke to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama City

What is the cheapest month to book a flight from Roanoke to Panama City, Florida?

Currently, September is the cheapest month in which you can book a flight from Roanoke to Panama City, Florida (average of $186). Flying from Roanoke to Panama City, Florida in March is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to ECP?

Find hourly flight availability from Roanoke to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 44% on flights from Roanoke to Panama City, Florida by exploring options for tickets in the evening.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 3, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Roanoke to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,038 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City, Florida?

    Airlines like Delta and American Airlines fly from Roanoke to Panama City, Florida in about 4h 37m. The time it takes to get you to your destination can typically vary by up to 31m. The distance from Roanoke to Panama City, Florida is about 585 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Roanoke to Panama City, Florida round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, Florida, with prices starting at $248. Another option worth looking into is Delta, starting at $248 round trip. These flights start at 24% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Roanoke to Panama City, Florida one-way?

    The cheapest airlines for a one-way flight from Roanoke to Panama City, Florida are Delta ($239), United Airlines ($279), and American Airlines ($339).

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Panama City, Florida?

    Currently, September is the cheapest month in which you can book a flight from Roanoke to Panama City, Florida (average of $186). Flying from Roanoke to Panama City, Florida in March is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Roanoke to Panama City

Discover the top 2 airlines that operate flights from Roanoke to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$313FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$348FlexibilityNo cancel feeOn-timeN/A

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