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Panama City

$269+ Cheap flights from Roanoke to Panama City, FL (ROA - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — ECP
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Roanoke to Panama City

Cheapest flights from Roanoke to Panama City
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 am
ROA
-
ECP
1 stop3h 17m
Delta
Sun 6/147:05 pm
ECP
-
ROA
1 stop3h 44m
Delta
Deal found 1/27$269
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:00 am
ROA
-
ECP
1 stop3h 39m
Delta
Thu 2/196:06 pm
ECP
-
ROA
1 stop5h 00m
Delta
Deal found 1/27$274
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:51 pm
ROA
-
ECP
1 stop4h 13m
Delta
Tue 3/315:30 pm
ECP
-
ROA
1 stop5h 34m
Delta
Deal found 1/28$279
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:00 am
ROA
-
ECP
1 stop3h 40m
Delta
Mon 3/306:43 pm
ECP
-
ROA
1 stop4h 36m
Delta
Deal found 1/28$284
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:00 am
ROA
-
ECP
1 stop3h 17m
Delta
Fri 6/267:05 pm
ECP
-
ROA
1 stop3h 44m
Delta
Deal found 1/27$294
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/107:05 am
ROA
-
ECP
1 stop6h 05m
Delta
Wed 2/186:00 am
ECP
-
ROA
1 stop3h 30m
Delta
Deal found 1/27$299
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
ROA
-
ECP
1 stop3h 17m
Delta
Sun 5/316:00 am
ECP
-
ROA
1 stop3h 35m
Delta
Deal found 1/28$343
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
ROA
-
ECP
1 stop3h 40m
Delta
Thu 4/96:43 pm
ECP
-
ROA
1 stop4h 21m
Delta
Deal found 1/27$344
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:02 pm
ROA
-
ECP
1 stop4h 39m
American Airlines
Sun 5/316:43 pm
ECP
-
ROA
1 stop4h 00m
American Airlines
Deal found 1/28$348
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1112:43 pm
ROA
-
ECP
1 stop5h 50m
American Airlines
Thu 2/197:19 am
ECP
-
ROA
2 stops12h 11m
American Airlines
Deal found 1/27$367
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:00 am
ROA
-
ECP
1 stop3h 17m
Delta
Sun 6/287:05 pm
ECP
-
ROA
1 stop3h 44m
Delta
Deal found 1/27$369

Find flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

Popular in

November

Cheapest in

August

Average price

$318
Provider with most accurate pricing for Roanoke-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Panama City NW Florida Beaches flights.
Search Deals
From Roanoke to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Roanoke

Fly to

Panama City

Route

Depart

Return

Price

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Thu 6/11

6:00 am-8:17 am

1 stop3h 17m

Panama City NW Florida Beaches

Sun 6/14

7:05 pm-11:49 pm

1 stop3h 44m

$269

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 2/11

6:00 am-8:39 am

1 stop3h 39m

Panama City NW Florida Beaches

Thu 2/19

6:06 pm-12:06 am

1 stop5h 00m

$274

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Tue 3/24

6:00 am-10:23 am

1 stop5h 23m

Panama City NW Florida Beaches

Tue 3/31

5:30 pm-12:04 am

1 stop5h 34m

$279

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 3/25

7:51 pm-11:04 pm

1 stop4h 13m

Panama City NW Florida Beaches

Tue 3/31

5:30 pm-12:04 am

1 stop5h 34m

$279

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Fri 6/19

6:00 am-8:17 am

1 stop3h 17m

Panama City NW Florida Beaches

Fri 6/26

7:05 pm-11:49 pm

1 stop3h 44m

$279

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Sun 3/22

6:00 am-8:40 am

1 stop3h 40m

Panama City NW Florida Beaches

Mon 3/30

6:43 pm-12:19 am

1 stop4h 36m

$284

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Wed 5/27

6:00 am-8:17 am

1 stop3h 17m

Panama City NW Florida Beaches

Sun 5/31

6:00 am-10:35 am

1 stop3h 35m

$343

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Thu 4/2

6:00 am-8:40 am

1 stop3h 40m

Panama City NW Florida Beaches

Thu 4/9

6:43 pm-12:04 am

1 stop4h 21m

$344

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Thu 7/16

6:00 am-8:15 am

1 stop3h 15m

Panama City NW Florida Beaches

Sun 7/19

7:05 pm-11:50 pm

1 stop3h 45m

$344

RoanokePanama City

ROA - ECP

ROAECP

Roanoke

Thu 2/5

6:00 am-8:39 am

1 stop3h 39m

$390

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 11 results
1
2

Compare providers for flights from Roanoke to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama City

What is the cheapest month to book a flight from Roanoke to Panama City, Florida?

Currently, September is the cheapest month in which you can book a flight from Roanoke to Panama City, Florida (average of $186). Flying from Roanoke to Panama City, Florida in March is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Roanoke to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,205 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City, Florida?

    Airlines like Delta fly from Roanoke to Panama City, Florida in about 3h 17m. The time it takes to get you to your destination can typically vary by up to . The distance from Roanoke to Panama City, Florida is about 585 mi.

  • What are the cheapest airlines flying from Roanoke to Panama City, Florida round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, Florida, with prices starting at $248. Another option worth looking into is Delta, starting at $248 round trip. These flights start at 31% lower than the current average price 3 months from now.

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Panama City, Florida?

    Currently, September is the cheapest month in which you can book a flight from Roanoke to Panama City, Florida (average of $186). Flying from Roanoke to Panama City, Florida in March is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Top 2 airlines flying from Roanoke to Panama City

Discover the top 2 airlines that operate flights from Roanoke to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$308FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$395FlexibilityNo cancel feeOn-timeN/A

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