Panama City

$367+ Cheap flights from Mexico to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
Mar 20 — Mar 271
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Cheap flight deals from Mexico to Panama City

Cheapest flights from Mexico to Panama City
Explore the most affordable flight options available from Mexico to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:40 am
MEX
-
ECP
2 stops11h 11m
Delta
Tue 5/1911:39 am
ECP
-
MEX
1 stop7h 42m
Delta
Deal found 2/17$537
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:35 am
MEX
-
ECP
2 stops17h 11m
American Airlines
Tue 5/1911:43 am
ECP
-
MEX
2 stops11h 37m
American Airlines
Deal found 2/17$551
This Aeromexico deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:15 pm
MEX
-
ECP
1 stop6h 32m
Aeromexico
Fri 10/307:45 am
ECP
-
MEX
1 stop14h 25m
Aeromexico
Deal found 2/17$557
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:20 pm
MEX
-
ECP
2 stops18h 23m
United Airlines
Mon 3/162:10 pm
ECP
-
MEX
2 stops24h 10m
United Airlines
Deal found 2/17$560
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:50 am
MEX
-
ECP
1 stop14h 07m
United Airlines
Mon 3/165:03 pm
ECP
-
MEX
1 stop17h 02m
United Airlines
Deal found 2/17$581
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:20 pm
MEX
-
ECP
1 stop20h 44m
United Airlines
Sun 3/1510:24 am
ECP
-
MEX
2 stops23h 41m
United Airlines
Deal found 2/16$594
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:40 pm
MEX
-
ECP
2 stops16h 04m
United Airlines
Fri 5/82:14 pm
ECP
-
MEX
2 stops26h 26m
United Airlines
Deal found 2/14$601
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:50 am
MEX
-
ECP
2 stops9h 46m
Delta
Fri 5/811:39 am
ECP
-
MEX
2 stops11h 31m
Delta
Deal found 2/14$620
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/74:45 am
MEX
-
ECP
1 stop16h 12m
United Airlines
Thu 3/126:30 am
ECP
-
MEX
1 stop27h 35m
United Airlines
Deal found 2/16$635

Find flight deals from Mexico to Panama City

Keep the following information in mind while searching for Mexico to Panama City flight deals. Data was last updated February 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$537
(United Airlines)

One-way from

$367

Popular in

December

Cheapest in

April

Average price

$511
Provider with most accurate pricing for Mexico City Benito Juarez-Panama City NW Florida Beaches flight deals.
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Panama City NW Florida Beaches flights.
From Mexico to Panama City NW Florida Beaches
One-way flight from Mexico to Panama City NW Florida Beaches
Highest demand for flights based on searches. 18% potential increase in price ($127 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Mexico to Panama City that are best for you.

Fly from

Mexico

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 5/13

7:05 am-2:04 pm

1 stop5h 59m

Panama City NW Florida Beaches

Tue 5/19

11:39 am-9:21 pm

1 stop10h 42m

$537

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 5/13

5:35 am-11:46 pm

2 stops17h 11m

Panama City NW Florida Beaches

Tue 5/19

11:43 am-10:20 pm

2 stops11h 37m

$551

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sat 5/16

7:05 am-6:36 pm

1 stop10h 31m

Panama City NW Florida Beaches

Mon 5/18

1:50 pm-9:21 pm

1 stop8h 31m

$558

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 3/12

6:50 am-9:57 pm

1 stop14h 07m

Panama City NW Florida Beaches

Mon 3/16

5:03 pm-11:15 am

1 stop19h 12m

$560

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 3/13

6:50 am-9:57 pm

1 stop14h 07m

Panama City NW Florida Beaches

Mon 3/16

5:03 pm-9:05 am

1 stop17h 02m

$581

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Mon 5/4

8:40 am-6:00 pm

1 stop8h 20m

Panama City NW Florida Beaches

Fri 5/8

7:41 am-1:55 pm

1 stop7h 14m

$581

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 3/19

2:20 pm-9:57 pm

1 stop6h 37m

$367

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 3/18

9:05 am-4:12 pm

1 stop6h 07m

$367

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 3/26

4:45 pm-9:57 pm

1 stop28h 12m

$368

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 3/15

8:40 am-7:27 pm

1 stop9h 47m

$388

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/14

Showing 1-10 of 15 results
1
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Best time to book a flight from Mexico to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Panama City

What is the cheapest month to book a flight from Mexico to Panama City, Florida?

Currently, August is the cheapest month in which you can book a flight from Mexico to Panama City, Florida (average of $377). Flying from Mexico to Panama City, Florida in December is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 18, 2026.
Read through reviews of airlines operating flights from Mexico to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.3

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Comfort

7.3

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Related info for your journey

Find useful and relevant information for your journey from Mexico to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from Mexico?

    For a flight from Mexico to Panama City, you will be flying into NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • How long is the flight from Mexico to Panama City, Florida?

    A quick flight from Mexico to Panama City, Florida can take about 5h 59m. Delta provides one of the quickest options available for as low as $537. Mexico and Panama City, Florida are separated by a distance of 1121 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Mexico to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Panama City.

  • Can I find deals for business class flights from Mexico to Panama City?

    Yes. Cheapflights offers flight deals from Mexico to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Panama City, Florida?

    Currently, August is the cheapest month in which you can book a flight from Mexico to Panama City, Florida (average of $377). Flying from Mexico to Panama City, Florida in December is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Mexico to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Mexico to Panama City

Discover the top airline that operate flights from Mexico to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$468Average$578FlexibilityNo cancel feeOn-time69%

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