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Panama City

$545+ Cheap flights from Mexico to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheap flight deals from Mexico to Panama City

Cheapest flights from Mexico to Panama City
Explore the most affordable flight options available from Mexico to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This Aeromexico deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:05 amMEX - ECP
1 stop6h 14mAeromexico
Mon 12/292:04 pmECP - MEX
2 stops19h 46mAeromexico
Deal found 12/28$794

Find flight deals from Mexico to Panama City

Keep the following information in mind while searching for Mexico to Panama City flight deals. Data was last updated December 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Popular in

January

Cheapest in

July

Average price

$659
Provider with most accurate pricing for Mexico City Benito Juarez-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Panama City NW Florida Beaches flights.
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Mexico to Panama City that are best for you.

Fly from

Mexico

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 5/8

9:05 am-10:46 pm

2 stops12h 41m

Panama City NW Florida Beaches

Sun 5/10

6:00 am-3:30 pm

2 stops10h 30m

$545

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Best time to book a flight from Mexico to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico to Panama City

What is the cheapest month to book a flight from Mexico to Panama City, Florida?

Currently, August is the cheapest month in which you can book a flight from Mexico to Panama City, Florida (average of $377). Flying from Mexico to Panama City, Florida in December is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 30, 2025.
Read through reviews of airlines operating flights from Mexico to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,121 reviews

Entertainment

7.1

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,121 reviews
United Airlines
7.4
Good
9,121 reviews

Entertainment

7.1

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Mexico to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mexico?

    For a flight from Mexico to Panama City, you will be flying into NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • Can I find deals for flights from Mexico to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico to Panama City.

  • Can I find deals for business class flights from Mexico to Panama City?

    Yes. Cheapflights offers flight deals from Mexico to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico to Panama City, Florida?

    Currently, August is the cheapest month in which you can book a flight from Mexico to Panama City, Florida (average of $377). Flying from Mexico to Panama City, Florida in December is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top airline flying from Mexico to Panama City

Discover the top airline that operate flights from Mexico to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$468Average$578FlexibilityNo cancel feeOn-time69%

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