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Panama City

$157+ Cheap flights from Buffalo to Panama City, FL (BUF - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — ECP
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheapflights Tip: The best prices from Buffalo to Panama City NW Florida Beaches are usually found in February or July, booked 90 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Buffalo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$329
(Delta)

One-way from

$157
(American Airlines)

Popular in

April

Cheapest in

February

Average price

$436
Provider with most accurate pricing for Buffalo-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Panama City NW Florida Beaches flights.
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From Buffalo to Panama City NW Florida Beaches
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One-way flight from Buffalo to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 17% potential increase in price ($92 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Buffalo to Panama City

Cheapest flights from Buffalo to Panama City
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:10 pmBUF - ECP
1 stop4h 42mDelta
Tue 12/96:00 amECP - BUF
1 stop4h 04mDelta
Deal found 10/28$329
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:30 amBUF - ECP
2 stops9h 30mSouthwest
Tue 12/97:15 amECP - BUF
1 stop5h 10mSouthwest
Deal found 10/28$334
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:25 pmBUF - ECP
1 stop5h 42mDelta
Mon 12/86:00 amECP - BUF
1 stop4h 04mDelta
Deal found 10/28$350
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:04 amBUF - ECP
1 stop5h 34mAmerican Airlines
Wed 12/317:15 amECP - BUF
2 stops7h 49mAmerican Airlines
Deal found 10/27$380
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:43 pmBUF - ECP
2 stops7h 06mAmerican Airlines
Mon 12/81:23 pmECP - BUF
2 stops8h 34mAmerican Airlines
Deal found 10/28$390
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:05 pmBUF - ECP
1 stop4h 50mDelta
Fri 11/214:26 pmECP - BUF
1 stop6h 24mDelta
Deal found 10/28$427

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Buffalo

Fly to

Panama City

Route

Depart

Return

Price

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Sat 12/6

12:10 pm-3:52 pm

1 stop4h 42m

Panama City NW Florida Beaches

Tue 12/9

6:00 am-11:04 am

1 stop4h 04m

$329

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Sat 12/6

7:20 pm-12:04 am

1 stop5h 44m

Panama City NW Florida Beaches

Tue 12/9

12:08 pm-5:50 pm

1 stop4h 42m

$329

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Sat 12/6

8:30 am-5:00 pm

2 stops9h 30m

Panama City NW Florida Beaches

Tue 12/9

7:15 am-1:25 pm

1 stop5h 10m

$334

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Mon 12/1

6:25 pm-11:07 pm

1 stop5h 42m

Panama City NW Florida Beaches

Mon 12/8

6:59 pm-11:59 pm

1 stop4h 00m

$350

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Wed 12/17

7:04 am-11:38 am

1 stop5h 34m

Panama City NW Florida Beaches

Wed 12/31

7:15 am-4:04 pm

2 stops7h 49m

$380

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Sat 11/15

12:05 pm-3:55 pm

1 stop4h 50m

Panama City NW Florida Beaches

Fri 11/21

4:26 pm-11:50 pm

1 stop6h 24m

$427

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Thu 12/11

7:20 pm-11:55 pm

1 stop5h 35m

$157

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Sun 11/2

7:00 am-4:23 pm

2 stops10h 23m

$464

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Sun 11/2

5:00 am-9:19 am

1 stop5h 19m

$469

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

Thu 12/11

6:00 am-4:11 pm

3 stops11h 11m

$819

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Compare providers for flights from Buffalo to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Panama City

How far ahead should I book a flight from Buffalo to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to Panama City. Price data was last updated on October 24, 2025.

The best time to book flights from Buffalo to Panama City, Florida is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Panama City, Florida (average of $145). Flying from Buffalo to Panama City, Florida in July is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to ECP?

Find hourly flight availability from Buffalo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s typically best to fly out from Buffalo to Panama City, Florida in the evening. Doing so could potentially save you 15% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Buffalo to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,992 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Panama City, Florida?

    Delta, American Airlines, and Southwest can get you from Buffalo to Panama City, Florida in just under 4h 42m. Your travel time can differ by up to 4h 48m. Airlines will cover a distance of 952 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to Panama City, Florida round-trip?

    Our cheapest airline available from Buffalo to Panama City, Florida is Delta. Our recent data shows that you can find tickets from as low as $270 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $292 and $381 round-trip. Delta is priced at 38% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Buffalo to Panama City, Florida one-way?

    One-way options have recently been found by users for as low as $157 on American Airlines. Other airlines that offer cheap prices include United Airlines from $464 and Delta from $469 one-way.

  • Can I find deals for flights from Buffalo to Panama City that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama City.

  • Can I find deals for business class flights from Buffalo to Panama City?

    Yes. Cheapflights offers flight deals from Buffalo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Panama City, Florida (average of $145). Flying from Buffalo to Panama City, Florida in July is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top 3 airlines flying from Buffalo to Panama City

Discover the top 3 airlines that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$270Average$418FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$292Average$482FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$381Average$582FlexibilityNo cancel feeOn-time63%

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