HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$206+ Cheap flights from Buffalo to Panama City, FL (BUF - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — ECP
oct. 11 — oct. 181
sam. 10/11
sam. 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Buffalo to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Buffalo to Panama City NW Florida Beaches are usually found in September or October, booked 46 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Buffalo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septembre 11, 2025.

Round-trip from

$206
(American Airlines)

Popular in

April

Cheapest in

September

Average price

$336
From Buffalo to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Buffalo to Panama City

Cheapest flights from Buffalo to Panama City
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 11/87:12 pmBUF - ECP
1 stop5h 41mAmerican Airlines
mar. 11/115:50 pmECP - BUF
1 stop4h 36mAmerican Airlines
Deal found 9/10$206
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 10/45:10 pmBUF - ECP
1 stop6h 53mDelta
mer. 10/86:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$214
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 10/255:14 pmBUF - ECP
1 stop6h 27mDelta
jeu. 10/306:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$222
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 10/247:30 pmBUF - ECP
1 stop4h 40mDelta
mar. 10/286:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$232
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/277:30 pmBUF - ECP
1 stop4h 40mDelta
ven. 10/316:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$248
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 10/266:03 amBUF - ECP
1 stop6h 29mDelta
jeu. 10/306:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$261
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 10/266:03 amBUF - ECP
1 stop6h 29mDelta
ven. 10/316:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$274
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 10/187:38 pmBUF - ECP
1 stop5h 06mAmerican Airlines
mer. 10/226:44 amECP - BUF
1 stop4h 40mAmerican Airlines
Deal found 9/11$276
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 10/237:30 pmBUF - ECP
1 stop4h 40mDelta
mar. 10/286:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$281
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/146:00 amBUF - ECP
1 stop5h 19mDelta
sam. 10/186:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$284
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 10/34:43 pmBUF - ECP
1 stop3h 47mDelta
mar. 10/76:00 amECP - BUF
1 stop4h 01mDelta
Deal found 9/11$289

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 11, 2025.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Buffalo

Fly to

Panama City

Route

Depart

Return

Price

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

mar. 10/21

7:30 pm-11:10 pm

1 stop4h 40m

Panama City NW Florida Beaches

sam. 10/25

5:32 pm-11:39 pm

1 stop5h 07m

$206

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

sam. 10/25

5:14 pm-10:41 pm

1 stop6h 27m

Panama City NW Florida Beaches

mer. 10/29

6:00 am-11:01 am

1 stop4h 01m

$206

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

sam. 11/8

12:50 pm-11:53 pm

2 stops12h 03m

Panama City NW Florida Beaches

mar. 11/11

5:50 pm-11:26 pm

1 stop4h 36m

$211

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

sam. 10/25

5:14 pm-10:41 pm

1 stop6h 27m

Panama City NW Florida Beaches

jeu. 10/30

6:00 am-11:01 am

1 stop4h 01m

$222

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

jeu. 10/23

7:30 pm-11:10 pm

1 stop4h 40m

Panama City NW Florida Beaches

mar. 10/28

6:00 am-11:01 am

1 stop4h 01m

$281

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

lun. 10/20

7:30 pm-11:10 pm

1 stop4h 40m

Panama City NW Florida Beaches

sam. 10/25

5:32 pm-11:39 pm

1 stop5h 07m

$284

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

mar. 10/14

6:00 am-10:19 am

1 stop5h 19m

Panama City NW Florida Beaches

sam. 10/18

6:00 am-11:01 am

1 stop4h 01m

$284

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

mar. 10/7

7:30 pm-11:10 pm

1 stop4h 40m

Panama City NW Florida Beaches

dim. 10/12

6:00 am-11:01 am

1 stop4h 01m

$289

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

jeu. 10/2

4:43 pm-7:30 pm

1 stop3h 47m

Panama City NW Florida Beaches

mar. 10/7

6:00 am-11:01 am

1 stop4h 01m

$289

BuffaloPanama City

BUF - ECP

BUFECP

Buffalo

sam. 10/18

7:38 pm-11:44 pm

1 stop5h 06m

Panama City NW Florida Beaches

jeu. 10/23

5:30 am-11:04 am

1 stop4h 34m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 12 results
1
2

Best time to book a flight from Buffalo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Panama City

How far ahead should I book a flight from Buffalo to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to Panama City. Price data was last updated on August 29, 2025.

The best time to book flights from Buffalo to Panama City, Florida is 46 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Panama City, Florida (average of $346). Flying from Buffalo to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to ECP?

Find hourly flight availability from Buffalo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septembre 11, 2025.

It’s typically best to fly out from Buffalo to Panama City, Florida in the evening. Doing so could potentially save you 16% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated septembre 11, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Buffalo to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Panama City, Florida?

    Delta and American Airlines can get you from Buffalo to Panama City, Florida in just under 4h 40m. Your travel time can differ by up to 7h 23m. Airlines will cover a distance of 952 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to Panama City, Florida round-trip?

    Our cheapest airline available from Buffalo to Panama City, Florida is Delta. Our recent data shows that you can find tickets from as low as $286 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $347 and $396 round-trip. Delta is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Buffalo to Panama City that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama City.

  • Can I find deals for business class flights from Buffalo to Panama City?

    Yes. Cheapflights offers flight deals from Buffalo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Panama City, Florida (average of $346). Flying from Buffalo to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Buffalo to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Miami flights
Newark to Fort Lauderdale flights
Newark to Miami flights
LaGuardia to Fort Lauderdale flights
LaGuardia to Miami flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to Fort Lauderdale flights
Newark to Orlando flights
LaGuardia to Orlando flights
LaGuardia to Tampa flights
John F Kennedy Intl to West Palm Beach flights
Newark to Tampa flights
John F Kennedy Intl to Tampa flights
Newark to West Palm Beach flights
LaGuardia to West Palm Beach flights
Islip to Orlando flights
Newark to Fort Myers flights
John F Kennedy Intl to Fort Myers flights
Buffalo to Orlando flights
White Plains to Orlando flights
John F Kennedy Intl to Sarasota flights
LaGuardia to Fort Myers flights
John F Kennedy Intl to Jacksonville flights
Newark to Jacksonville flights
Syracuse to Orlando flights
Newark to Sarasota flights
Newark to Key West flights
Buffalo to Fort Lauderdale flights
LaGuardia to Jacksonville flights
Albany to Orlando flights
LaGuardia to Sarasota flights
Stewart to Orlando flights
White Plains to Fort Lauderdale flights
Rochester to Orlando flights
White Plains to West Palm Beach flights
John F Kennedy Intl to Key West flights
Stewart to Fort Lauderdale flights
Islip to West Palm Beach flights
White Plains to Miami flights
White Plains to Fort Myers flights
Islip to Tampa flights
Islip to Fort Lauderdale flights
White Plains to Tampa flights
LaGuardia to Pensacola flights
Buffalo to Miami flights
Rochester to Fort Lauderdale flights
Buffalo to Tampa flights
LaGuardia to Key West flights
Albany to Fort Lauderdale flights
Islip to Fort Myers flights

Top 3 airlines flying from Buffalo to Panama City

Discover the top 3 airlines that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$286Average$441FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$347Average$495FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$396Average$582FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.