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$204+ Cheap flights from Panama City, FL to Buffalo (ECP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — BUF
mai 28 — juin 41
jeu. 5/28
jeu. 6/4
1 adult, Economy
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Cheap flight deals from Panama City to Buffalo

Cheapest flights from Panama City to Buffalo
Explore the most affordable flight options available from Panama City to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on avril 28, 2026.

This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/155:07 pm
ECP
-
BUF
1 stop5h 52m
Delta
mer. 8/197:40 pm
BUF
-
ECP
1 stop4h 06m
Delta
Deal found 4/26$371
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/159:00 am
ECP
-
BUF
2 stops13h 59m
United Airlines
mer. 8/197:00 am
BUF
-
ECP
1 stop6h 58m
United Airlines
Deal found 4/26$376
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 7/235:07 pm
ECP
-
BUF
1 stop5h 52m
Delta
dim. 7/265:12 pm
BUF
-
ECP
1 stop4h 34m
Delta
Deal found 4/28$407
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/114:40 pm
ECP
-
BUF
1 stop6h 10m
American Airlines
jeu. 5/287:31 pm
BUF
-
ECP
1 stop5h 09m
American Airlines
Deal found 4/26$426
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/1312:05 pm
ECP
-
BUF
2 stops8h 40m
Southwest
sam. 5/162:00 pm
BUF
-
ECP
1 stop4h 50m
Southwest
Deal found 4/24$431
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/119:55 am
ECP
-
BUF
1 stop7h 20m
Southwest
jeu. 5/2812:40 pm
BUF
-
ECP
2 stops10h 00m
Southwest
Deal found 4/26$452
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/181:39 pm
ECP
-
BUF
1 stop6h 29m
United Airlines
mer. 8/197:00 am
BUF
-
ECP
1 stop6h 58m
United Airlines
Deal found 4/27$485
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 5/99:50 am
ECP
-
BUF
1 stop5h 25m
Southwest
mer. 5/139:25 am
BUF
-
ECP
1 stop4h 55m
Southwest
Deal found 4/24$487

Find flight deals from Panama City to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated avril 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$371
(Delta)

One-way from

$204
(Delta)

Popular in

December

Cheapest in

September

Average price

$729
Provider with most accurate pricing for Panama City NW Florida Beaches-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Buffalo flights.
Search Deals
From Panama City NW Florida Beaches to Buffalo
Search Deals
One-way flight from Panama City NW Florida Beaches to Buffalo
Search Deals
Highest demand for flights based on searches. 41% potential increase in price ($312 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated avril 28, 2026.
Use the filters below to find and compare flights from Panama City to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

mer. 7/15

10:25 am-11:59 pm

2 stops12h 34m

Buffalo

mer. 8/19

6:00 am-12:58 pm

2 stops7h 58m

$399

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

jeu. 7/23

5:07 pm-11:59 pm

1 stop5h 52m

Buffalo

dim. 7/26

5:12 pm-8:46 pm

1 stop4h 34m

$407

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

ven. 7/24

6:41 pm-11:59 pm

1 stop4h 18m

Buffalo

dim. 7/26

6:05 am-12:23 pm

1 stop7h 18m

$407

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

mer. 5/13

4:40 pm-11:50 pm

1 stop6h 10m

Buffalo

sam. 5/16

7:28 pm-11:46 pm

1 stop5h 18m

$426
Quickest round-trip

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

sam. 5/9

9:50 am-4:15 pm

1 stop5h 25m

Buffalo

mer. 5/13

9:25 am-1:20 pm

1 stop4h 55m

$487

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

lun. 5/11

9:55 am-6:15 pm

1 stop7h 20m

Buffalo

ven. 5/15

6:00 am-11:35 am

1 stop6h 35m

$487
Cheapest one-way

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

lun. 7/13

6:41 pm-11:59 pm

1 stop4h 18m

$204

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

mar. 7/14

5:07 pm-11:59 pm

1 stop5h 52m

$204

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

mer. 5/13

4:40 pm-11:50 pm

1 stop6h 10m

$244

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

mer. 5/13

11:46 am-6:44 pm

1 stop5h 58m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Panama City to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Buffalo in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated avril 28, 2026.
Read reviews from past customers who have flown American Airlines from Panama City to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,674 reviews

Boarding

7.5

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,674 reviews
American Airlines
7.1
Good
11,674 reviews

Boarding

7.5

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Panama City to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Buffalo?

    United Airlines and Delta can get you from Panama City, Florida to Buffalo in just under 5h 52m. Your travel time can differ by up to 6h 42m. Panama City, Florida and Buffalo are separated by a distance of 952 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Panama City, Florida to Buffalo round-trip?

    Flying on American Airlines is currently your cheapest option to Buffalo, with prices starting at $236. You may be able to fly from Panama City, Florida to Buffalo for 45% less than the average price by searching for this airline.

  • Can I find deals for flights from Panama City to Buffalo that include hotel bookings?

    Yes. In addition to deals on Panama City to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Buffalo.

  • Can I find deals for business class flights from Panama City to Buffalo?

    Yes. Cheapflights offers flight deals from Panama City to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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Top airline flying from Panama City to Buffalo

Discover the top airline that operate flights from Panama City to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated avril 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$367FlexibilityNo cancel feeOn-time71%

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