$218+ Cheap flights from Buffalo to Panama City, FL (BUF - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — ECP
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Panama City
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Cheapest flights from Buffalo to Panama CityExplore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:45 pm -
2 stops6h 30m
Sat 12/57:50 am -
1 stop7h 10m
Deal found 9/14![Southwest logo]()
$286
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:50 am -
1 stop5h 38m
Sat 10/3111:04 am -
1 stop6h 59m
Deal found 9/16![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:58 pm -
1 stop5h 11m
Sat 12/511:54 am -
1 stop5h 11m
Deal found 9/14![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:53 pm -
1 stop5h 00m
Fri 10/237:15 am -
1 stop6h 51m
Deal found 9/16![American Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Tue 10/207:12 am -
1 stop6h 41m
Deal found 9/16![Delta logo]()
$321
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop6h 43m
Mon 10/266:20 pm -
1 stop4h 39m
Deal found 9/15![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:53 pm -
1 stop5h 00m
Fri 10/237:15 am -
1 stop6h 51m
Deal found 9/15![American Airlines logo]()
$340
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Mon 10/196:00 am -
1 stop4h 13m
Deal found 9/16![Delta logo]()
$342
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:35 am -
2 stops12h 01m
Sat 10/319:06 am -
2 stops10h 45m
Deal found 9/16![United Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Sat 10/176:00 am -
1 stop4h 16m
Deal found 9/16![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:55 pm -
1 stop5h 23m
Mon 10/266:20 pm -
1 stop4h 39m
Deal found 9/15![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Fri 10/236:00 am -
1 stop4h 16m
Deal found 9/16![Delta logo]()
$362
Best flights from Buffalo to Panama CityDiscover carefully curated flight deals from Buffalo to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Buffalo to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Wed 10/216:00 am -
1 stop4h 16m
Deal found 9/16![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:35 am -
2 stops12h 01m
Sat 10/319:06 am -
2 stops10h 45m
Deal found 9/16![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:30 pm -
2 stops8h 25m
Fri 10/231:50 pm -
2 stops8h 55m
Deal found 9/16![Southwest logo]()
$440
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:55 pm -
2 stops9h 58m
Fri 10/237:15 am -
2 stops10h 54m
Deal found 9/12![American Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
1 stop6h 43m
Mon 11/26:00 am -
1 stop4h 16m
Deal found 9/15![Delta logo]()
$335
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:46 am -
1 stop5h 28m
Wed 10/289:06 am -
2 stops12h 53m
Deal found 9/15![United Airlines logo]()
$366
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:55 pm -
1 stop5h 23m
Mon 10/266:20 pm -
1 stop4h 39m
Deal found 9/15![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:20 pm -
1 stop6h 58m
Mon 11/29:19 am -
1 stop5h 45m
Deal found 9/15![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Sun 10/186:00 am -
1 stop4h 16m
Deal found 9/16![Delta logo]()
$404
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop6h 43m
Sun 11/15:37 pm -
1 stop5h 22m
Deal found 9/16![Delta logo]()
$416
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:59 pm -
1 stop5h 04m
Sun 10/257:12 am -
1 stop6h 46m
Deal found 9/12![Delta logo]()
$457
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:59 pm -
1 stop5h 26m
Tue 10/67:12 am -
1 stop6h 41m
Deal found 9/14![Delta logo]()
$498
Last-minute flights from Buffalo to Panama CityDiscover last-minute flight deals from Buffalo to Panama City. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Panama City. Data last updated September 17, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Wed 10/216:00 am -
1 stop4h 16m
Deal found 9/16![Delta logo]()
$321
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Mon 10/196:00 am -
1 stop4h 13m
Deal found 9/16![Delta logo]()
$342
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Sat 10/176:00 am -
1 stop4h 16m
Deal found 9/16![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 43m
Fri 10/236:00 am -
1 stop4h 16m
Deal found 9/16![Delta logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:53 pm -
1 stop5h 00m
Fri 10/237:15 am -
1 stop6h 51m
Deal found 9/16![American Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop6h 43m
Mon 10/266:20 pm -
1 stop4h 39m
Deal found 9/15![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:53 pm -
1 stop5h 00m
Fri 10/237:15 am -
1 stop6h 51m
Deal found 9/15![American Airlines logo]()
$340
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:55 pm -
1 stop5h 23m
Mon 10/266:20 pm -
1 stop4h 39m
Deal found 9/15![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:46 am -
1 stop5h 28m
Wed 10/289:06 am -
2 stops12h 53m
Deal found 9/15![United Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:50 am -
1 stop5h 38m
Sat 10/3111:04 am -
1 stop6h 59m
Deal found 9/16![American Airlines logo]()
$291
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:35 am -
2 stops12h 01m
Sat 10/319:06 am -
2 stops10h 45m
Deal found 9/16![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:30 am -
1 stop7h 00m
Sat 10/317:40 am -
2 stops9h 15m
Deal found 9/16![Southwest logo]()
$365
One-way flights from Buffalo to Panama CitySearch for one-way flight options from Buffalo to Panama City. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Buffalo to Panama City. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:53 pm -
1 stop5h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$218
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:53 pm -
1 stop5h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:45 am -
1 stop5h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$404
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:02 pm -
2 stops10h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Delta logo]()
$485
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:00 am -
3 stops29h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$831
Find flight deals from Buffalo to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $286 (Southwest) |
One-way from | $218 (American Airlines) |
Popular in | April |
Cheapest in | August |
Average price | $586 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Sat 10/10
7:53 pm-11:53 pm
1 stop5h 00m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$218
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Wed 10/14
6:00 am-11:43 am
1 stop6h 43m
Panama City NW Florida Beaches
Wed 10/21
6:00 am-11:16 am
1 stop4h 16m
$321
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Thu 10/29
6:00 am-11:43 am
1 stop6h 43m
Panama City NW Florida Beaches
Mon 11/2
6:00 am-11:16 am
1 stop4h 16m
$335
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Wed 10/28
10:35 am-9:36 pm
2 stops12h 01m
Panama City NW Florida Beaches
Sat 10/31
9:06 am-8:51 pm
2 stops10h 45m
$345
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Fri 10/23
6:55 pm-11:18 pm
1 stop5h 23m
Panama City NW Florida Beaches
Mon 10/26
6:20 pm-11:59 pm
1 stop4h 39m
$355
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Fri 10/30
5:20 pm-11:18 pm
1 stop6h 58m
Panama City NW Florida Beaches
Mon 11/2
9:19 am-4:04 pm
1 stop5h 45m
$355
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Sat 10/24
10:46 am-3:14 pm
1 stop5h 28m
Panama City NW Florida Beaches
Wed 10/28
9:06 am-10:59 pm
2 stops12h 53m
$366
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Thu 9/24
11:45 am-3:45 pm
1 stop5h 00m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$404
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Wed 10/14
6:00 am-11:43 am
1 stop6h 43m
Panama City NW Florida Beaches
Sun 10/18
6:00 am-11:16 am
1 stop4h 16m
$404
BuffaloPanama City
BUF Buffalo - ECP Panama City NW Florida Beaches
BUFECP
Buffalo
Fri 10/30
6:00 am-11:43 am
1 stop6h 43m
Panama City NW Florida Beaches
Sun 11/1
5:37 pm-11:59 pm
1 stop5h 22m
$416
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
BUF-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Panama City
What is the cheapest month to book a flight from Buffalo to Panama City, Florida?
Currently, August is the cheapest month in which you can book a flight from Buffalo to Panama City, Florida (average of $340). Flying from Buffalo to Panama City, Florida in April is currently the most expensive (average of $676). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to Panama City, Florida?
Airfare is below average for this route at the moment.
Buffalo to Panama City, Florida flights typically cost between $404 and $597 in December.The cheapest round-trip price found within the last 5 days was $286 on Southwest (Dec 2-Dec 5).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 17, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Buffalo to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
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Top 3 airlines flying from Buffalo to Panama City
Discover the top 3 airlines that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$414 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$499 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$361 | Average$473 | FlexibilityNo cancel fee | On-time63% |